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工程建设与设计 2025年第1期 128-130页

作者：王琦佳丽水市城投基础设施建设有限公司浙江丽水323000

依托丽水市区某市政道路路网开展透水沥青路面结构设计,重点对不同设计参数的沥青路面储水效果进行对比研究。结果表明,基层厚度增加会导致结构透水能力增强;砂性土渗透系数较大,透水效果好,更适合于透水性沥青路面结构土基建设。

关键词：透水沥青路面结构设计储水效果

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向日葵锈菌冬孢子及锈孢子萌发条件的研究

中国油料作物学报 2025年第1期47卷 204-210页

作者：王佳运路妍孔祥久景岚内蒙古农业大学园艺与植物保护学院内蒙古呼和浩特010011

为了解向日葵锈菌(Puccinia helianthi)冬孢子及锈孢子的生物学特性,对这两种类型孢子最适萌发条件进行了筛选研究。结果表明,采集的新鲜冬孢子在室温下存放超过180 d才可萌发。存放于-20℃萌发效果较好,180 d萌发率可达到39.45%,420 d... 详细信息

为了解向日葵锈菌(Puccinia helianthi)冬孢子及锈孢子的生物学特性,对这两种类型孢子最适萌发条件进行了筛选研究。结果表明,采集的新鲜冬孢子在室温下存放超过180 d才可萌发。存放于-20℃萌发效果较好,180 d萌发率可达到39.45%,420 d时,冬孢子活性基本丧失。冬孢子在水琼脂培养基上于15℃12 h即可萌发,48 h后达到萌发高峰,萌发率为31.89%;锈孢子在水琼脂培养基上于20℃2 h开始萌发,24 h后萌发率最高,萌发率为54.33%;水琼脂培养基浓度对冬孢子的萌发无影响,0.50%琼脂培养基最适宜锈孢子的萌发;温度15℃、pH 6的条件有利于冬孢子萌发;20℃、 pH 7是锈孢子萌发的最适宜温度和pH值;光照对冬孢子萌发没有影响,但是对锈孢子萌发有促进作用。10 g/L低浓度的叶片浸出液可以促进两种孢子的萌发,高浓度抑制萌发。

关键词：向日葵锈菌冬孢子锈孢子萌发条件

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Tauroursodeoxycholic acid targets HSP90 to promote protein homeostasis and extends healthy lifespan

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Science China(Life Sciences) 2025年第2期68卷 416-430页

作者： jia-Yu Liu Yao Wang Yue Guo Run-qi Zheng Yun-Ying Wang Yan-Yan Shen Yan-Hong Liu Ai-Ping Cao Rui-Bo Wang Bo-Yang Xie Shuai jiang qiu-Ying Han Jing Chen Fang-Ting Dong Kun He Na Wang Xin Pan Tao Li Tao Zhou Ai-Ling Li qing Xia Wei-Na Zhang Nanhu Laboratory National Center of Biomedical AnalysisBeijing 100850China

As the elderly population expands,the pursuit of therapeutics to reduce morbidity and extend lifespan has become increasingly *** an FDA-approved drug for chronic cholestatic liver diseases,tauroursodeoxycholic acid(TUDCA),a natural bile acid,offers additional health benefits beyond liver ***,we show that TUDCA extends the lifespan and healthspan of ***,oral supplementation of TUDCA improves fitness in old mice,including clinically relevant phenotypes,exercise capacity and cognitive ***,TUDCA treatment drives broad transcriptional changes correlated with anti-aging ***,we discover that TUDCA targets the chaperone HSP90 to promote its protein refolding *** collaboration further alleviates aging-induced endoplasmic reticulum(ER)stress and facilitates protein homeostasis,thus offering resistance to *** summary,our findings uncover new molecular links between an endogenous metabolite and protein homeostasis,and propose a novel anti-aging strategy that could improve both lifespan and healthspan.

关键词： tauroursodeoxycholic acid lifespan healthspan protein homeostasis

Intervention and treatment of Alzheimer's disease

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Life Research 2025年第1期8卷 44-50页

作者： Dan-Lin Yue-Ran Ma Tian-Yang Jun-Ru Yang jia-Rui Ma Wen-Rui Wu Si-qi He Yu-Hong Lü Chang-Wu Yue Key Laboratory of Microbial Drug Innovation and Transformation School of MedicineYan’an UniversityYan’an 716000China Shaanxi Engineering Technological Research Center for Conversation Utilization of Regional Biological Resources Yan’an UniversityYan’an 716000China

Background:Alzheimer's disease(AD)is a degenerative disease that occurs in the central nervous system and is characterized by progressive cognitive dysfunction and behavioral *** main pathological mechanisms are amyloid-βaccumulation(Aβ)and hyperphosphorylation of tau protein(P-TAU).Objective:however,there are no effective drugs for the treatment of AD,so the intervention and treatment of AD still need further ***:We did a search and summary some of the new potential drugs and other interventions for the treatment of ***:We found relevant anti-Aβ,anti-tau,anti-aging,the Apolipoprotein(APOE)control drugs and intervention in AD through exercise and ***:because most of these drugs are in clinical trials,more effort is needed to develop anti-AD drugs.

关键词： AD aging APOE Aβ Tau drugs intervention

Spatial Variability of Soil Salinization and Alkalization in the Northern Plain Irrigation Area of Yinchuan,Ningxia

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Journal of Resources and Ecology 2025年第1期16卷 148-158页

作者： NIU Zilu SONG Chunling WANG Lei qi Tuoye CHEN Maosheng jiaNG Shuting ZHANG Li XU Lizhen LIU jia School of Ecology and Environment Ningxia UniversityYinchuan 750021China Rural Economics Institute Ningxia Academy of Social SciencesYinchuan 750021China Ningxia Yellow River Wetland Ecosystem National Positioning Observation and Research Station Yinchuan 750021China Huaqing Agricultural Co. LtdBeijing 100084China

Soil salinization is a type of soil degradation phenomenon caused by the gradual accumulation of salt in soil due to natural processes or improper irrigation *** the spatial variations of salinization is the basis for salinized land management and resource *** Yinbei Plain irrigation area of Ningxia as the research area,154 sampling points were set up and soil samples were collected at depths from 0-100 cm in six layers to determine the pH value and total salt content of the *** geostatistics and GIS were used to study the spatial variations of soil pH and total salt content in the irrigation *** results show three important aspects of this system.(1)The soil in the study area is alkaline soil with pH values ranging from 8.18 to 10.22,and the pH increases with increasing soil *** pH values of soil at 0-10 cm are significantly higher than at depths of 10-20 cm and 20-80 cm(P<0.05).The variation coefficients of the soil pH value in each layer are less than 10%,which is characterized as weak *** total salt content of soil decreases with increasing soil depth,ranging from 0.24 to 14.95 g kg^(-1).The total salt content of soil in the surface layer at 0-10 cm was significantly higher than in the lower soil layers(P<0.05).The coefficient of variation of total salt content showed moderate variability except at depths of 10-20 cm and 80-100 *** layers have variabilities of more than 100%,indicating strong variability.(2)The semi-variance function fitting of pH and total salt showed that the soil pH value in each soil layer depth block base ratio ranged from 28.1%to 61.2%,which indicates a medium spatial correlation,and the spatial variability was mainly influenced by the joint action of human activities and natural *** total salt block base ratio of each soil layer ranged from 5.5%to 13.3%,which indicates strong spatial *** variation among soil samples is mainly caused by natural str

关键词： soil total salt soil pH geostatistics Kriging interpolation spatial variation the northern plain irrigation area of Yinchuan

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气候金融实践与发展建议

气候变化研究进展 2025年第1期21卷 78-90页

作者：吕学都陈佳琪葛慧朱乙丹中国气象局国家气候中心广东南方碳捕集和封存产业中心中节能衡准科技服务(北京)有限公司

本文从气候金融的定义及起源出发，分析了气候金融在国内外的发展历程、目前的状况、面临的问题、挑战和机遇，重点剖析了多边开发银行气候金融的创新实践及借鉴意义。最后对促进中国未来气候金融发展提出了7条建议，即完善气候金融政... 详细信息

本文从气候金融的定义及起源出发，分析了气候金融在国内外的发展历程、目前的状况、面临的问题、挑战和机遇，重点剖析了多边开发银行气候金融的创新实践及借鉴意义。最后对促进中国未来气候金融发展提出了7条建议，即完善气候金融政策体系、建立多元化融资渠道、加强气候金融服务体系建设、提升数字化技术应用、建设高质量气候投融资项目库、探索气候金融量化方法，以及加强国际合作与交流。

关键词：气候变化气候金融绿色金融

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红色文化融入大学生思想政治教育的价值意蕴与实践路径

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教育理论与实践 2025年第3期45卷 47-50页

作者：李佳祺徐成芳内蒙古大学马克思主义学院内蒙古呼和浩特010021

红色文化是党的宝贵精神资源,具有鲜明的先进性、革命性、实践性、人民性和民族性。红色文化对于强化大学生对党和国家的认同,增强高校思想政治教育的丰富性、生动性与实效性,增强大学生文化自觉,坚定文化自信都具有重要意义。红色文化... 详细信息

红色文化是党的宝贵精神资源,具有鲜明的先进性、革命性、实践性、人民性和民族性。红色文化对于强化大学生对党和国家的认同,增强高校思想政治教育的丰富性、生动性与实效性,增强大学生文化自觉,坚定文化自信都具有重要意义。红色文化融入大学生思想政治教育应该精选教育内容,推进红色文化融入教学过程;丰富教育形式,助力红色文化融入校园活动;打造优质思政教育师资队伍,充分发挥教育者的主导作用;开展教育评价,保障融入的实效性等多个维度开展。

关键词：大学生思想政治教育红色文化教育内容教育形式教育评价

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Quantifcation of solvent-mediated host-ion interaction in graphite intercalation compounds for extreme-condition Li-ion batteries

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Journal of Energy Chemistry 2025年第2期 723-732页

作者： jia-Zhen Zhao Fu-Da Yu Ji-Huai Wu Zhang lan Yi-Ming Xie Le-qing Fan lan-Fang Que Zhen-Bo Wang Engineering Research Center of Environment-Friendly Functional Materials Ministry of Education Institute of Materials Physical Chemistry Huaqiao University MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage State Key Laboratory of Space Power-Sources School of Chemistry and Chemical Engineering Harbin Institute of Technology College of Materials Science and Engineering Shenzhen University

Achieving simultaneous fast-charging capabilities and low-temperature adaptability in graphite-based lithium-ion batteries（LIBs） with an acceptable cycle life remains ***,an ether-based electrolyte with temperature-adaptive Li+solvation structure is designed for graphite,and stable Li+/solvent co-intercalation has been achieved at *** revealed by in-situ variable temperature（-20℃） X-ray diffraction（XRD）,the poor compatibility of graphite in ether-based electrolyte at 25℃is mainly due to the continuous electrolyte decomposition and the in-plane rearrangement below0.5 *** results in a significant irreversible capacity,while latter maintains graphite in a prolonged state of extreme expansion,ultimately leading to its exfoliation and *** contrast,low temperature triggers the rearra ngement of Li+solvation structu re with stronger Li+/solvent binding energy and sho rter Li+-O bond length,which is conducive for reversible Li+/solvent co-intercalation and reducing the time of graphite in an extreme expansion *** addition,the co-intercalation of solvents minimizes the interaction between Li-ions and host graphite,endowing graphite with fast diffusion *** expected,the graphite anode delivers about 84% of the capacity at room temperature at-20℃.Moreover,within6 min,about 83%,73%,and 43% of the capacity could be charged at 25,-20,and-40℃,respectively.

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Advances in imaging techniques for tumor microenvironment evaluation in hepatocellular carcinoma

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World Journal of Gastroenterology 2025年第10期31卷 30-37页

作者： Li-Li Wang Fa-Chang Zhang Han-Xin Xu Dian-Dian Deng Bing-Jie Ren qi Tan Ya-Xin Liu Wen-Hui Zhao jia-Le Lu Department of Radiology The First Hospital of Lanzhou UniversityLanzhou 730030Gansu ProvinceChina First Clinical Medical School of lanzhou University Lanzhou UniversityLanzhou 730030Gansu ProvinceChina

The tumor microenvironment(TME)plays a critical role in the development and treatment of liver cancer,which ranks sixth in incidence and third in mortality worldwide,according to the“Global Cancer Statistics 2022”.Hepatocellular carcinoma(HCC),the most common form of liver cancer,is heavily influenced by the TME,which affects tumor growth,invasion,metastasis,and the response to various *** advancements in surgery,liver transplantation,targeted therapies,and immunotherapy,the complexity of the TME often limits treatment efficacy,especially in advanced-stage HCC *** TME consists of a dynamic interaction between tumor cells,immune cells,fibroblasts,blood vessels,and signaling molecules,all of which contribute to cancer progression and therapy *** the HCC TME is essential for designing effective,personalized treatments and improving patient *** research highlights the value of imaging technologies as non-invasive tools to evaluate the TME,offering new possibilities for more targeted therapies and better prognosis monitoring in HCC patients.

关键词： Hepatocellular carcinoma Tumor microenvironment Imaging diagnosis Non-invasive assessment Molecular imaging

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有头疽治疗方式研究进展

中外医学研究 2025年第3期23卷 176-180页

作者：贾岚李大勇辽宁中医药大学辽宁沈阳110847 辽宁中医药大学附属医院

有头疽作为糖尿病严重并发症之一,其患病感染者,可合并剧烈疼痛、高热、脓毒血症等,严重影响患者的生活质量,甚至危及生命。随着医学领域及医疗研究的不断完善,对有头疽的研究逐渐深入,其治疗方式也变得多样化,文章通过查阅文献,汇总从2... 详细信息

有头疽作为糖尿病严重并发症之一,其患病感染者,可合并剧烈疼痛、高热、脓毒血症等,严重影响患者的生活质量,甚至危及生命。随着医学领域及医疗研究的不断完善,对有头疽的研究逐渐深入,其治疗方式也变得多样化,文章通过查阅文献,汇总从2000年至今有头疽的中西医治疗方法,针对有头疽一病阐述合理、有效、经济且快速的治疗方法,为患病者治疗疾病提供新的思路。

关键词：有头疽中医治法西医治法综述