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Attributable Causes of Breast Cancer and Ovarian Cancer in China:Reproductive Factors,Oral Contraceptives and Hormone Replacement Therapy

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Chinese Journal of Cancer Research 2012年第1期24卷 9-17页

作者： Li Li jia ji jian-bing Wang Mayineur Niyazi You-lin Qiao Paolo Boffettas Deportment of Gynecology the People's Hospitul of Xinjiung Uygur Autonomous RegionUrumqi 830011China Department of Cancer Epidemiology Cancer InstituteChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China Division of Pharmaceutics College of Pharmacythe Ohio State UniversityColumbusOH 43210USA Department of Epidemiology and Statistics Institute of Basic Medical SciencesChinese Academy of Medical Sciences&School of Basic MedicinePeking Union Medical CollegeBeijing 100730China The Tisch Cancer Institute Mount Sinai School of MedicineNew YorkNY 10029USA International Prevention Research Institute Lyon 69006France

Objective： To provide an evidence-based, consistent assessment of the burden of breast cancer attributable to reproductive factors （RFs, including nulliparity, mean number of children, age at first birth and breastfeeding）, use of oral contraceptives （OCs, restricted to the age group of 15-49 years）, and hormone replacement therapy （HRT）, as well as of the burden of ovarian cancer attributable to the mean number of children in China in 2005. Methods： We derived the prevalence of these risk factors and the relative risk of breast and ovarian cancer from national surveys or large-scale studies conducted in China. In the case of RFs, we compared the exposure distributions in 2001 and counterfactual exposure. Results： Exposure of RFs in 2002 was found to account for 6.74% of breast cancer, corresponding to 9,617 cases and 2,769 deaths, and for 2.78% of ovarian cancer （712 cases, 294 deaths）. The decrease in mean number of children alone was responsible for 1.47% of breast cancer and 2.78% of ovarian cancer. The prevalence of OC use was 1.74% and the population attributable fraction （PAF） of breast cancer was 0.71%, corresponding to 310 cases and 90 deaths. The PAF of breast cancer due to HRT was 0.31%, resulting in 297 cases and 85 deaths. Conclusion： RFs changes in China contributed to a sizable fraction of breast and ovarian cancer incidence and mortality, whereas HRT and OCs accounted for relatively low incidence of breast cancer in China.

关键词： Reproductive factors Oral contraceptives Hormone replacement therapy Cancer Population attributable fraction

一例Mn配合物对有机染料分子的光催化降解性能

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凯里学院学报 2024年第3期42卷 31-37页

作者：侯银玲季甲任小花黄乖徐超凯里学院贵州凯里556011

采用水热法,以MnSO_(4)·H_(2)O和4-(3,5-二羧基苯基)-吡啶甲酸(H_(3)pja)为原料合成了一例新的Mn配合物,其分子式为[Mn_(3)(H_(2)pja)_(2)(Hpja)_(2)(H_(2)O)_(8)]·2H_(2)O(简称配合物Mn).采用X-射线单晶衍射对其进行了结构解析,结果表明该配合物为零维结构.采用X射线粉末衍射表征了其相纯度.并且重点研究了配合物Mn在可见光照射下对有机染料分子甲基橙(MO)、罗丹明B(RhB)的光催化降解性能.结果表明,配合物Mn对甲基橙有一定的催化降解效果,降解率为61.9%,而对罗丹明B的催化降解效果更好,降解率可达98.5%.

关键词：配合物晶体结构有机染料分子光催化降解

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Self-Supervised Graph Neural Networks for Accurate Prediction of Néel Temperature

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Chinese Physics Letters 2022年第6期39卷 5-11页

作者： jian-Gang Kong Qing-Xu Li jian Li Yu Liu jia-ji Zhu School of Science Chongqing University of Posts and TelecommunicationsChongqing 400065China Institute for Advanced Sciences Chongqing University of Posts and TelecommunicationsChongqing 400065China Southwest Center for Theoretical Physics Chongqing UniversityChongqing 401331China Inspur Electronic Information Industry Co. LtdBeijing 100085China

Antiferromagnetic materials are exciting quantum materials with rich physics and great potential for *** the other hand, an accurate and efficient theoretical method is highly demanded for determining critical transition temperatures, Néel temperatures, of antiferromagnetic materials. The powerful graph neural networks(GNNs) that succeed in predicting material properties lose their advantage in predicting magnetic properties due to the small dataset of magnetic materials, while conventional machine learning models heavily depend on the quality of material descriptors. We propose a new strategy to extract high-level material representations by utilizing self-supervised training of GNNs on large-scale unlabeled datasets. According to the dimensional reduction analysis, we find that the learned knowledge about elements and magnetism transfers to the generated atomic vector representations. Compared with popular manually constructed descriptors and crystal graph convolutional neural networks, self-supervised material representations can help us to obtain a more accurate and efficient model for Néel temperatures, and the trained model can successfully predict high Néel temperature antiferromagnetic materials. Our self-supervised GNN may serve as a universal pre-training framework for various material properties.

关键词： utilizing networks neural

Asymmetric twin-field quantum key distribution with both statistical and intensity fluctuations

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Communications in Theoretical Physics 2020年第6期72卷 37-42页

作者： Shao-Fu He Yang Wang jia-ji Li Wan-Su Bao Henan Key Laboratory of Quantum Information and Cryptography SSF IEUZhengzhouHenan 450001China Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefeiAnhui 230026China

Twin-field quantum key distribution(TF-QKD)is a disruptive innovation which is able to overcome the rate-distance limit of QKD without trusted *** the proposal of the first TF-QKD protocol,theoretical and experimental breakthroughs have been made to enhance its ***,there still exist some practical issues waiting for *** this paper,we examine the performances of asymmetric TF-QKD protocol with unstable light sources and limited data *** statistical fluctuations of the parameters are estimated employing Azuma’s *** numerical simulations,we compare the secret key rates of the asymmetric TF-QKD protocol with different data sizes and variant intensity fluctuation *** results demonstrate that both statistical and intensity fluctuations have significant impacts on the performance of asymmetric TF-QKD.

关键词： twin-field quantum key distribution asymmetrical losses statistical fluctuations intensity fluctuations

Electrical and thermoelectric study of two-dimensional crystal of NbSe2

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Chinese Physics B 2020年第8期29卷 137-142页

作者： Xin-Qi Li Zhi-Lin Li jia-ji Zhao Xiao-Song Wu State Key Laboratory for Artificial Microstructure and Mesoscopic Physics Beijing Key Laboratory of Quantum DevicesPeking UniversityBeijing 100871China Frontiers Science Center for Nano-optoelectronics and Collaborative Innovation Center of Quantum Matter Beijing 100871China

We report experimental investigation of the resistivity and Nernst effect in two-dimensional(2D)NbSe2 crystals.A strongly enhanced Nernst effect,100 times larger than that in bulk NbSe2,caused by moving vortices is observed in thin *** is found that in the low temperature,high magnetic field regime,pinning effects show little dependence on the thickness and resistivity of the superconductor *** Nernst signals persist above the superconducting transition,suggesting that the Nernst effect is a sensitive probe to superconducting fluctuations.A magnetic field induced superconductor-insulator transition(SIT)is evident,which is surprising in that such a SIT usually takes place in disordered dirty superconductors,while our samples are highly crystalline and close to the clean ***,our results expand the scope of SIT into 2D crystal clean superconductors.

关键词： two-dimensional superconductivity Nernst effect superconducting fluctuations superconductor-insulator transition

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不同有机物添加的营养液对生菜生长的影响

浙江农业科学 2024年第5期65卷 1169-1173页

作者：张兴洪季佳南刘灿光倪维晨江苏善港生态农业科技有限公司江苏苏州215600 南农大(常熟)新农村发展研究院有限公司江苏苏州215500

试验以意大利耐抽薹生菜为试材,采用基质栽培的方式,研究添加不同有机物(尿素、腐殖酸、黄腐酸钾、EDTA-2Na(乙二胺四乙酸二钠))的营养液配方对生菜生长及品质的影响。试验结果表明,低浓度尿素替代无机营养液中的硝态氮能有效提升生菜... 详细信息

试验以意大利耐抽薹生菜为试材,采用基质栽培的方式,研究添加不同有机物(尿素、腐殖酸、黄腐酸钾、EDTA-2Na(乙二胺四乙酸二钠))的营养液配方对生菜生长及品质的影响。试验结果表明,低浓度尿素替代无机营养液中的硝态氮能有效提升生菜地上部和地下部鲜重,更高浓度的尿素则会起抑制作用;添加50 mg·L^(-1)和100 mg·L^(-1)的EDTA-2Na可明显提升生菜中的可溶性糖含量;腐殖酸营养液和尿素替代40%硝态氮处理均能有效提升可溶性蛋白含量。综合研究,用尿素替代40%硝态氮处理可作为生菜水培的优化营养液配方。

关键词：生菜营养液营养品质

Identification of Differentially Expressed Genes During Anther Abortion of Taigu Genic Male Sterile Wheat by Combining Suppression Subtractive Hybridization and cDNA Array

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Journal of Integrative Plant Biology 2006年第11期48卷 1348-1354页

作者： Qing-Shan Chang Rong-Hua Zhou Xiu-Ying Kong Zeng-Liang Yu ji-Zeng jia Key Laboratory of Crop Germplasm and Biotechnology Ministry of Agriculture Institute of Crop Sciences Chinese Academy of Agricultural Sciences the National Key Facility for Crop Gene Resources and Genetic Improvement Beijing 100081 China Ion Beam Bioengineering Laboratory Institute of Plasma Physics the Chinese Academy of Sciences Hefei 230031 China

Talgu Genlc Male Sterile Wheat （TGMSW; Trltlcum aestlvum L.）, a dominant genic male sterile germplasm, is of considerable value in the genetic Improvement of wheat because of Its stable Inherence, complete male abortion, and high cross-fertilization rate. To Identify specially transcribed genes In sterile anther, a suppression subtractlve hybridization （aSH） library was constructed with sterile anther as the tester and fertile anther as the driver. A total of 2 304 SSH Inserts amplified by polymerase chain reaction were arrayed using robotic printing. The cDNA arrays were hybridized with 32P-labeled probes prepared from the RNA of forward- and reverse-subtracted anthers. Ninety-six clones were scored as upregulated in sterile anthers compared with the corresponding fertile anthers and some clones were selected for sequencing and analysis In GenBank. Based on their putative functions, 87 non-redundant clones were classified Into the following groups：（i） eight genes Involved In metabolic processes; （11） four material transportation genes; （iii） three signal transductlon-assoclated genes; （iv） four stress response and senescence-associated protein genes; （v） seven other functional protein genes; （vi） five genes with no known function; and （vii） another 56 genes with no match to the databases. To test the hybridization efficiency, eight genes were selected and analyzed by Northern blot. The results of the present study provide a comprehensive overview of the genes and gene products Involved In anther abortion In TGMSW.

关键词： anther cDNA array suppression subtractive hybridization Taigu Genic Male Sterile Wheat.

Detecting Environmental Contamination of Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2)in Isolation Wards and Fever Clinics

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Biomedical and Environmental Sciences 2020年第12期33卷 943-947页

作者： CHEN Guo Min ji jia jia jiaNG Shuai XIAO Ya Qi ZHANG Ren Li HUANG Da Na LIU Hui YU Shu Yuan Environment and Health Department Shenzhen Center for Disease Control and PreventionShenzhen 518055GuangdongChina Institute of Pathogen Biology Shenzhen Center for Disease Control and PreventionShenzhen 518055GuangdongChina

Coronavirus disease 2019(COVID-19)is an acute respiratory disease with an incubation period of 1 to14 d,which is caused by a novel coronavirus(SARS-CoV-2),which has spread throughout China and *** from SARS,MERS,and influenza,the dominant clinical manifestations of COVID-19 are fever and cough,whereas upper respiratory symptoms and gastrointestinal symptoms are ***,the elderly and those with underlying diseases become more seriously ill after infection[1].

关键词： respiratory acute diseases

The Characterization and Geographical Distribution of the Genes Responsible for Vernalization Requirement in Chinese Bread Wheat

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Journal of Integrative Plant Biology 2009年第4期51卷 423-432页

作者： Qing-Ming Sun Rong-Hua Zhou Li-Feng Gao Guang-Yao Zhao ji-Zeng jia College of Biological Sciences China Agricultural University Beijing 100094 China Department of Crop Molecular Biology Institute of Crop Sciences Chinese Academy of Agricultural Sciences Beijing 100081 China

The frequency and distribution of the major vernalization requirement genes and their effects on growth habits were studied. Of the 551 bread wheat genotypes tested, seven allelic combinations of the three Vrn-1 genes were found to be responsible for the spring habit, three for the facultative habit and one for the winter habit. The three Vrn-1 genes behaved additiveiy with the dominant allele of Vrn-A1 exerting the strongest effect. The allele combinations of the facultative genotypes and the discovery of spring genotypes with ＂winter＂ allele of Vrn-1 implied the presence of as yet unidentified alleles/genes for vernalization response. The dominant alleles of the three Vrn-1 genes were found in all ten ecological regions where wheat is cultivated in China, with Vrn-D1 as the most common allele in nine and Vrn-A1 in one. The combination of vrn-A1vrn-B1Vrn-D1 was the predominant genotype in seven of the regions. Compared with landraces, improved varieties contain a higher proportion of the spring type. This was attributed by a higher frequency of the dominant Vrn-A1 and Vrn-B1 alleles in the latter, Correlations between Vrn-1 allelic constitutions and heading date, spike length, plant type as well as cold tolerance were established.

关键词： common wheat genotyping geographical distribution vernalization.