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Phosphomonoesterase Activities,Kinetics and Thermodynamics in a Paddy Soil After Receiving Swine Manure for Six Years

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Pedosphere 2015年第2期25卷 294-306页

作者： LI Liang LIANG Xin-Qiang LI Hua ji yuan-jing LIU jin YE Yu-Shi TIAN Guang-Ming CHEN Ying-Xu LUO Yong-Ming Institute of Environmental Science and Technology College of Environmental and Resources SciencesZhejiang University Zhejiang Academy of Agricultural Sciences Key Laboratory for Water Pollution Control and Environmental Safety Yantai Institute of Coastal Zone Research Chinese Academy of Sciences

Soil phosphomonoesterase plays a critical role in controlling phosphorus(P) cycling for crop nutrition,especially in P-deficient soils.A 6-year field experiment was conducted to evaluate soil phosphomonoesterase activities,kinetics and thermodynamics during rice growth stages after consistent swine manure application,to understand the impacts of swine manure amendment rates on soil chemical and enzymatic properties,and to investigate the correlations between soil enzymatic and chemical *** experiment was set out in a randomized complete block design with three replicates and five treatments including three swine manure rates(26,39,and 52 kg P ha^(-1),representing low,middle,and high application rates,respectively) and two controls(no-fertilizer and superphosphate at 26 kg P ha^(-1)).The results indicated that the grain yield and soil chemical properties were significantly improved with the application of P-based swine manure from 0 to 39 kg P ha^(-1);however,the differences between the 39(M_(39)) and 52 kg P ha^(-1) treatments(M_(52)) were not *** enzymatic property analysis indicated that acid phosphomonoesterase was the predominant phosphomonoesterase in the tested *** M_(39) and M_(52) treatments had relatively high initial velocity(V_0),maximal velocity(V_(max)),and activation grade(lgN_a) but low Michaelis constant(K_m),temperature coefficient(Q_(10)),activation energy(E_a),and activation enthalpy(ΔH),implying that the M_(39) and M_(52) treatments could stimulate the enzyme-catalyzed reactions more easily than all other *** correlation analysis showed that the distribution of soil phosphomonoesterase activities mainly followed the distributions of total C and total *** on these results,39 kg P ha^(-1) could be recommended as the most appropriate rate of swine manure amendment.

关键词： activation energy activation enthalpy enzyme-catalyzed reaction maximal velocity Michaelis constant

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球面收敛二元矢量喷管气动及红外特性研究:模拟地面状态

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航空动力学报 2017年第3期32卷 614-620页

作者：季靖远张靖周单勇征建生南京航空航天大学能源与动力学院江苏省航空动力系统重点实验室南京210016 先进航空发动机协同创新中心北京100191

采用数值模拟方法对涡扇发动机排气系统球面收敛二元矢量喷管的气动和红外辐射特性进行了研究,研究仅针对地面状态和俯仰偏转.结果表明:俯仰偏转角在小于20°范围内,俯仰偏转对排气系统推力系数和总压恢复系数的影响微弱,气动推力矢量... 详细信息

采用数值模拟方法对涡扇发动机排气系统球面收敛二元矢量喷管的气动和红外辐射特性进行了研究,研究仅针对地面状态和俯仰偏转.结果表明:俯仰偏转角在小于20°范围内,俯仰偏转对排气系统推力系数和总压恢复系数的影响微弱,气动推力矢量角与俯仰偏转角几乎相等;由于气体的容积性热辐射特征,喷管俯仰偏转角的变化引起高温喷流红外辐射的方向性变化明显,喷管俯仰偏转时的热喷流在3~5μm波段红外辐射呈现一定幅度的增加;排气系统在3~5μm波段的红外辐射峰值随俯仰偏转角的增加而趋于减小,其出现位置小于俯仰偏转角;在大的俯仰偏转角下,排气系统在垂直探测平面上方的红外辐射较无矢量偏转情形有所降低,但在探测面下方却有明显的增强,导致另一个峰值的出现.

关键词：排气系统球面收敛二元矢量喷管俯仰偏转气动特性红外辐射

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球面收敛二元矢量喷管气动及红外特性研究:模拟高空状态

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航空动力学报 2017年第2期32卷 390-397页

作者：征建生张靖周单勇季靖远南京航空航天大学能源与动力学院江苏省航空动力系统重点实验室南京210016 先进航空发动机协同创新中心北京100191

针对高空状态下球面收敛二元矢量喷管排气系统,通过数值模拟研究了喷管俯仰偏转角对排气系统气动和红外辐射特性的影响,并与地面状态进行了对比分析.在该研究参数范围内,研究结果表明:在俯仰偏转角为20°范围内,俯仰偏转对排气系统推力... 详细信息

针对高空状态下球面收敛二元矢量喷管排气系统,通过数值模拟研究了喷管俯仰偏转角对排气系统气动和红外辐射特性的影响,并与地面状态进行了对比分析.在该研究参数范围内,研究结果表明:在俯仰偏转角为20°范围内,俯仰偏转对排气系统推力系数和总压恢复系数的影响微弱,气动推力矢量角与俯仰偏转角几乎相等,高空状态下,喷管的推力系数和总压恢复系数下降0.5%与1.1%;热喷流峰值红外辐射强度仅为地面状态的12%~24%,排气系统的总体红外辐射强度峰值与地面状态下的比值峰值在0.35~0.45之间;随着下俯仰偏转角的增加,排气系统红外辐射峰值呈现下降的趋势.

关键词：高空状态球面收敛二元矢量喷管俯仰偏转气动特性红外辐射特性

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Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑yuan Yu jing Wu Guang Yin Fan‑Zhen jiao Zhong‑Zhen Yu jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

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FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression

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Neural Regeneration Research 2025年第7期20卷 2068-2083页

作者： jing Yao yuan Li Xi Liu Wenping Liang Yu Li Liyong Wu Zhe Wang Weihong Song The National Clinical Research Center for Geriatric Disease Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Neurology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Pediatrics The Second Affiliated Hospital and Yuying Children’s HospitalKey Laboratory of Alzheimer’s Disease of Zhejiang ProvinceInstitute of AgingWenzhou Medical UniversityWenzhouZhejiang ProvinceChina Oujiang Laboratory(Zhejiang Laboratory for Regenerative Medicine Visionand Brain Health)WenzhouZhejiang ProvinceChina

Alzheimer's disease is characterized by deposition of amyloid-β,which forms extracellular neuritic plaques,and accumulation of hyperphosphorylated tau,which aggregates to form intraneuronal neurofibrillary tangles,in the *** NLRP3 inflammasome may play a role in the transition from amyloid-βdeposition to tau phosphorylation and *** NLRP3 is primarily found in brain microglia,and tau is predominantly located in neurons,it has been suggested that NLRP3 expressed by microglia indirectly triggers tau phosphorylation by upregulating the expression of pro-inflammatory ***,we found that neurons also express NLRP3 in vitro and in vivo,and that neuronal NLRP3 regulates tau *** biochemical methods,we mapped the minimal NLRP3 promoter and identified FUBP3 as a transcription factor regulating NLRP3 expression in *** primary neurons and the neuroblastoma cell line Neuro2A,FUBP3 is required for endogenous NLRP3 expression and tau phosphorylation only when amyloid-βis *** the brains of aged wild-type mice and a mouse model of Alzheimer's disease,FUBP3 expression was markedly increased in cortical *** analysis suggested that FUBP3 plays a role in neuron-mediated immune *** also found that FUBP3 trimmed the 5′end of DNA fragments that it bound,implying that FUBP3 functions in stress-induced *** findings suggest that neuronal NLRP3 may be more directly involved in the amyloid-β-to–phospho-tau transition than microglial NLRP3,and that amyloid-βfundamentally alters the regulatory mechanism of NLRP3 expression in *** that FUBP3 was only expressed at low levels in young wild-type mice and was strongly upregulated in the brains of aged mice and Alzheimer's disease mice,FUBP3 could be a safe therapeutic target for preventing Alzheimer's disease progression.

关键词： 5′end trimming Alzheimer's disease amyloid-beta amyloid-β-dependent transcription FUBP3 inflammasome inflammation neuron NLRP3 tau transcription factor

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早期综合康复护理干预对换瓣术后患者康复的影响

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医学信息 2020年第7期33卷 178-180+189页

作者：季景媛张静天津市胸科医院内分泌科天津市胸科医院心脏康复科

目的观察早期综合康复护理干预对风湿性心脏病患者换瓣术后康复效果的影响。方法选择2018年1～12月于我院行单纯换瓣术治疗的254例风湿性心脏病患者作为研究对象,按随机数字表法为康复组(129例)与对照组(125例)。对照组患者术后给予常... 详细信息

目的观察早期综合康复护理干预对风湿性心脏病患者换瓣术后康复效果的影响。方法选择2018年1～12月于我院行单纯换瓣术治疗的254例风湿性心脏病患者作为研究对象,按随机数字表法为康复组(129例)与对照组(125例)。对照组患者术后给予常规护理,康复组患者在此基础上给予早期综合康复护理,比较两组术后心功能改善、生活质量及术后并发症发生情况。结果康复组心功能改善总有效率(96.90%)高于对照组(75.20%),差异有统计学意义(P<0.05);康复组并发症总发生率(6.98%)低于对照组(26.40%),差异有统计学意义(P<0.05);护理后,两组患者QOL-C30评分均较护理前上升,且康复组QOL-C30评分高于对照组,差异有统计学意义(P<0.05)。结论针对行换瓣术治疗的风湿性心脏病患者,术后实施早期综合康复护理干预有利于患者心功能改善,可降低术后并发症发生率及提高患者生活质量,值得应用。

关键词：风湿性心脏病心脏瓣膜置换术综合康复护理心功能生活质量

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基于FIB-SEM制备尖晶石微米颗粒的球差校正透射电镜样品

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电子显微学报 2021年第1期40卷 50-54页

作者：王磊曲迪姬静远白国人天津华慧芯科技集团有限公司天津300467 清华大学天津电子信息研究院高端光电子芯片创新中心天津300467

针对尖晶石微米颗粒材料,利用聚焦离子束扫描电镜双束系统(FIB-SEM),在传统透射电镜样品制备方法的基础上进行技术性改进,成功制备了高质量的球差校正透射电镜样品。并利用球差校正透射电镜成功观察到了尖晶石颗粒的截面原子结构,为更... 详细信息

针对尖晶石微米颗粒材料,利用聚焦离子束扫描电镜双束系统(FIB-SEM),在传统透射电镜样品制备方法的基础上进行技术性改进,成功制备了高质量的球差校正透射电镜样品。并利用球差校正透射电镜成功观察到了尖晶石颗粒的截面原子结构,为更深入地研究尖晶石材料的结构和性能奠定了基础。

关键词：聚焦离子束扫描电镜双束系统微米颗粒球差校正透射电镜样品

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3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration

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Nano-Micro Letters 2025年第2期17卷 18-45页

作者： Ke Yao Gaoying Hong Ximin yuan Weicheng Kong Pengcheng Xia yuanrong Li Yuewei Chen Nian Liu jing He Jue Shi Zihe Hu Yanyan Zhou Zhijian Xie Yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Liangzhu Laboratory Zhejiang UniversityHangzhou 310027People’s Republic of China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province College of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineHangzhou 310027People’s Republic of China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001People’s Republic of China Institute of Digital Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006People’s Republic of China

Hydrogel scaffolds have numerous potential applications in the tissue engineering ***,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical *** by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this ***,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent ***,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell ***,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT *** experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries.

关键词： 3D printing Tough hydrogel scaffold Functional surface structure Tissue regeneration Biomaterials

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移动端互动游戏对缓解心脏病患者术前焦虑的影响评价

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医学信息 2018年第22期31卷 181-183页

作者：季景媛赵锦庄媛天津市胸科医院心外科

目的探讨移动端互动游戏对缓解心脏病患者术前焦虑的影响。方法选择本院2017年1月～2018年1月收治的心脏病患者72例作为研究对象,随机分为对照组及观察组各36例,对照组为常规优质护理服务,观察组则增加移动端互动游戏干预,观察两组术前... 详细信息

目的探讨移动端互动游戏对缓解心脏病患者术前焦虑的影响。方法选择本院2017年1月～2018年1月收治的心脏病患者72例作为研究对象,随机分为对照组及观察组各36例,对照组为常规优质护理服务,观察组则增加移动端互动游戏干预,观察两组术前焦虑水平、生命体征及术后疼痛程度。结果术前1 d两组患者焦虑程度比较,差异无统计学意义(P>0.05);术前30 min两组患者焦虑水平均出现变化,其中观察组焦虑评分低于对照组(P0.05);术前30 min两组患者心率水平均出现变化,其中观察组心率低于对照组,差异有统计学意义(P0.05);术前30 min两组患者收缩压和舒张压均出现变化,其中观察组收缩压低于对照组(P0.05)。结论针对心脏病患者在护理中加入移动端互动游戏干预可进一步缓解其术前焦虑水平,确保其稳定生命体征,并缓解术后疼痛,提高患者生活质量。

关键词：移动端互动游戏心脏病焦虑程度

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白藜芦醇代谢物的研究进展

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西北植物学报 2007年第4期27卷 852-857页

作者：王娅宁尉亚辉郝浩永姬婧媛西北大学生命科学学院西部资源生物与现代生物技术省部共建教育部重点实验室西安710069

白藜芦醇是一些植物在受到生物和非生物胁迫时产生的一种植物抗毒素.它在植物体内会迅速被代谢而生产紫檀芪、云杉新苷、viniferins等代谢物.这些代谢物与白藜芦醇一样具有抗菌、消炎、抗血小板凝集、防止细胞癌变等一系列的生物活性,... 详细信息

白藜芦醇是一些植物在受到生物和非生物胁迫时产生的一种植物抗毒素.它在植物体内会迅速被代谢而生产紫檀芪、云杉新苷、viniferins等代谢物.这些代谢物与白藜芦醇一样具有抗菌、消炎、抗血小板凝集、防止细胞癌变等一系列的生物活性,且有些代谢物的选择性、稳定性远远大于白藜芦醇.本文对白藜芦醇代谢物中几种主要代谢物的合成途径、生物活性、代谢调控、检测方法等进行了综述.

关键词：白藜芦醇代谢物紫檀芪云杉新苷 viniferins

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