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Highly sensitive ratiometric fluorescent fiber matrices for oxygen sensing with micrometer spatial resolution

Bio-Design and Manufacturing 2024年第3期7卷 292-306页

作者： Giuliana Grasso Valentina Onesto Stefania Forciniti Eliana D’Amone Francesco Colella lara Pierantoni Valeria Famà Giuseppe Gigli Rui l.Reis j.Miguel Oliveira loretta l.del Mercato nstitute of Nanotechnology National Research Council(CNR-NANOTEC)c/o Campus Ecoteknevia Monteroni73100 LecceItaly Department of Mathematics and Physics“Ennio De Giorgi” University of Salentoc/o Campus Ecoteknevia Monteroni73100 LecceItaly 3B’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate laboratory 4806-909 Braga/GuimarãesPortugal Department of Experimental Medicine University of Salentoc/o Campus Ecoteknevia Monteroni73100 LecceItaly

Oxygen(O_(2))-sensing matrices are promising tools for the live monitoring of extracellular O_(2) consumption levels in long-term cell *** this study,ratiometric O_(2)-sensing membranes were prepared by electrospinning,an easy,low-cost,scalable,and robust method for fabricating ***(ε-caprolactone)and poly(dimethyl)siloxane polymers were blended with tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II)dichloride,which was used as the O_(2)-sensing probe,and rhodamine B isothiocyanate,which was used as the reference *** functionalized scaffolds were morphologically characterized by scanning electron microscopy,and their physicochemical profiles were obtained by Fourier transform infrared spectroscopy,thermogravimetric analysis,and water contact angle *** sensing capabilities were investigated by confocal laser scanning microscopy,performing photobleaching,reversibility,and calibration curve studies toward different dissolved O_(2)(DO)*** sensing nanofibers showed a high response to changes in DO concentrations in the physiological-pathological range from 0.5%to 20%and good stability under ratiometric *** addition,the sensing systems were highly biocompatible for cell growth promoting adhesiveness and growth of three cancer cell lines,namely metastatic melanoma cell line SK-MEl2,breast cancer cell line MCF-7,and pancreatic ductal adenocarcinoma cell line Panc-1,thus recreating a suitable biological environment in *** O_(2)-sensing biomaterials can potentially measure alterations in cell metabolism caused by changes in ambient O_(2)content during drug testing/validation and tissue regeneration processes.

关键词： Electrospinning Ruthenium(II)dichloride Oxygen sensors Ratiometric imaging Fluorescence

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Evidence for particle acceleration approaching PeV energies in the W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： lHAASO Collaboration Zhen Cao F.Aharonian Axikegu Y.x.Bai Y.W.Bao D.Bastieri x.j.Bi Y.j.Bi W.Bian A.V.Bukevich Q.Cao W.Y.Cao Zhe Cao j.Chang j.F.Chang A.M.Chen E.S.Chen H.x.Chen liang Chen lin Chen long Chen M.j.Chen M.l.Chen Q.H.Chen S.Chen S.H.Chen S.Z.Chen T.l.Chen Y.Chen N.Cheng Y.D.Cheng M.Y.Cui S.W.Cui x.H.Cui Y.D.Cui B.Z.Dai H.l.Dai Z.G.Dai Danzengluobu x.Q.Dong K.K.Duan j.H.Fan Y.Z.Fan j.Fang j.H.Fang K.Fang C.F.Feng H.Feng l.Feng S.H.Feng x.T.Feng Y.Feng Y.l.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao M.M.Ge l.S.Geng G.Giacinti G.H.Gong Q.B.Gou M.H.Gu F.l.Guo x.l.Guo Y.Q.Guo Y.Y.Guo Y.A.Han M.Hasan H.H.He H.N.He j.Y.He Y.He Y.K.Hor B.W.Hou C.Hou x.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.j.Huang x.T.Huang x.Y.Huang Y.Huang x.l.ji H.Y.jia K.jia K.jiang x.W.jiang Z.j.jiang M.jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.li C.M.li Cheng li Cong li D.li F.li H.B.li H.C.li jian li jie li K.li S.D.li W.l.li W.l.li x.R.li xin li Y.Z.li Zhe li Zhuo li E.W.liang Y.F.liang S.j.lin B.liu C.liu D.liu D.B.liu H.liu H.D.liu j.liu j.l.liu M.Y.liu R.Y.liu S.M.liu W.liu Y.liu Y.N.liu Q.luo Y.luo H.K.lv B.Q.Ma l.l.Ma x.H.Ma j.R.Mao Z.Min W.Mitthumsiri H.j.Mu Y.C.Nan A.Neronov l.j.Ou P.Pattarakijwanich Z.Y.Pei j.C.Qi M.Y.Qi B.Q.Qiao j.j.Qin A.Raza D.Ruffolo A.Sáiz M.Saeed D.Semikoz l.Shao O.Shchegolev x.D.Sheng F.W.Shu H.C.Song Yu.V.Stenkin V.Stepanov Y.Su D.x.Sun Q.N.Sun x.N.Sun Z.B.Sun j.Takata P.H.T.Tam Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang j.C.Wang Kai Wang Kai Wang l.P.Wang l.Y.Wang P.H.Wang R.Wang W.Wang x.G.Wang x.Y.Wang Y.Wang Y.D.Wang Y.j.Wang Z.H.Wang Z.x.Wang Zhen Wang Zheng Wang D.M.Wei j.j.Wei Y.j.Wei T.Wen C.Y.Wu H.R.Wu Q.W.Wu S.Wu x.F.Wu Y.S.Wu S.Q.xi j.xia G.M.xiang D.x.xiao G.xiao Y.l.xin Y.xing D.R.xiong Z.xiong D.l.xu R.F.xu R.x.xu W.l.xu l.xue D.H.Yan j.Z.Yan T.Yan C.W.Yang C.Y.Yang F.Yang F.F.Yang l.l.Yang M.j.Yang R.Z.Yang W.x.Yang Y.H.Yao Z.G.Yao l.Q.Yin N.Yin x.H.You Z.Y.You Y.H.Yu Q.Yuan H.Yue H.D.Zeng T.x.Zeng W.Zeng M.Zha B.B.Zhang F.Zhang H.Zhang 不详 Key laboratory of Particle Astrophysics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China university of Chinese Academy of Sciences Beijing 100049China TIANFu Cosmic Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 103980Heidelberg 69029Germany School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research of Russian Academy of Sciences Moscow 117312Russia Hebei Normal university Shijiazhuang 050024China university of Science and Technology of China Hefei 230026China State Key laboratory of Particle Detection and Electronics China Key laboratory of Dark Matter and Space Astronomy&Key laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311121China Key laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of Physics and Astronomy Yunnan UniversityKunming 650091China Key laboratory of Cosmic Rays(Tibet university) Ministry of EducationLhasa 850000China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Theγ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays(CRs)accelerated by the shock of supernova remnant(SNR)W51C and the dense molecular clouds in the adjacent star-forming region,***,the maximum acceleration capability of W51C for CRs remains *** on observations conducted with the large High Altitude Air Shower Observatory(lHAASO),we report a significant detection ofγrays emanating from the W51 complex,with energies from 2 to 200 *** lHAASO measurements,for the first time,extend theγ-ray emission from the W51 complex beyond 100 TeV and reveal a significant spectrum bending at tens of *** combining the"π^(0)-decay bump"featured data from Fermi-lAT,the broadbandγ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum,most likely providing the first evidence of SNRs serving as CR accelerators approaching the PeV ***,two young star clusters within W51B could also be theoretically viable to produce the most energeticγrays observed by *** findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs.

关键词： uHE c-ray Cosmic rays SNR W51C Star clusters

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Anneal-free ultra-low loss silicon nitride integrated photonics

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light(Science & Applications) 2024年第8期13卷 1565-1577页

作者： Debapam Bose Mark W.Harrington Andrei Isichenko Kaikai liu jiawei Wang Nitesh Chauhan Zachary l.Newman Daniel j.Blumenthal Department of Electrical and Computer Engineering University of California Santa BarbaraSanta BarbaraCA 93106USA Octave Photonics LouisvilleCO 80027USA

Heterogeneous and monolithic integration of the versatile low-loss silicon nitride platform with low-temperature materials such as silicon electronics and photonics,III–V compound semiconductors,lithium niobate,organics,and glasses has been inhibited by the need for high-temperature annealing as well as the need for different process flows for thin and thick *** techniques are needed to maintain the state-of-the-art losses,nonlinear properties,and CMOS-compatible processes while enabling this next generation of 3D silicon nitride *** report a significant advance in silicon nitride integrated photonics,demonstrating the lowest losses to date for an anneal-free process at a maximum temperature 250℃,with the same deuterated silane based fabrication flow,for nitride and oxide,for an order of magnitude range in nitride thickness without requiring stress mitigation or *** report record low anneal-free losses for both nitride core and oxide cladding,enabling 1.77 dBm^(-1) loss and 14.9 million Q for 80 nm nitride core waveguides,more than half an order magnitude lower loss than previously reported sub 300℃ *** 800 nm-thick nitride,we achieve as good as 8.66 dBm^(-1) loss and 4.03 million Q,the highest reported Q for a low temperature processed resonator with equivalent device area,with a median of loss and Q of 13.9 dBm^(-1) and 2.59 million each *** demonstrate laser stabilization with over 4 orders of magnitude frequency noise reduction using a thin nitride reference cavity,and using a thick nitride micro-resonator we demonstrate OPO,over two octave supercontinuum generation,and four-wave mixing and parametric gain with the lowest reported optical parametric oscillation threshold per unit resonator *** results represent a significant step towards a uniform ultra-low loss silicon nitride homogeneous and heterogeneous platform for both thin and thick waveguides capable of linear and nonlinear photonic circuits and

关键词： resonator thick free

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Determination of the number ofψ(3686)events taken at BESⅢ

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Chinese Physics C 2024年第9期48卷 8-20页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis x.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya K.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai x.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin j.F.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen H.Y.Chen M.l.Chen S.j.Chen S.l.Chen S.M.Chen T.Chen x.R.Chen x.T.Chen Y.B.Chen Y.Q.Chen Z.j.Chen Z.Y.Chen S.K.Choi G.Cibinetto F.Cossio j.j.Cui H.l.Dai j.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Ding x.x.Ding Y.Ding Y.Ding j.Dong l.Y.Dong M.Y.Dong x.Dong M.C.Du S.x.Du Y.Y.Duan Z.H.Duan P.Egorov Y.H.Fan j.Fang j.Fang S.S.Fang W.x.Fang Y.Fang Y.Q.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng j.H.Feng Y.T.Feng M.Fritsch C.D.Fu j.l.Fu Y.W.Fu H.Gao x.B.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia l.Ge P.T.Ge Z.W.Ge C.Geng E.M.Gersabeck A.Gilman K.Goetzen l.Gong W.x.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan Z.l.Guan A.Q.Guo l.B.Guo M.j.Guo R.P.Guo Y.P.Guo A.Guskov j.Gutierrez K.l.Han T.T.Han F.Hanisch x.Q.Hao F.A.Harris K.K.He K.l.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou x.T.Hou Y.R.Hou Z.l.Hou B.Y.Hu H.M.Hu j.F.Hu S.l.Hu T.Hu Y.Hu G.S.Huang K.x.Huang l.Q.Huang x.T.Huang Y.P.Huang T.Hussain F.Hölzken N.Hüsken N.in der Wiesche j.jackson S.janchiv j.H.jeong Q.ji Q.P.ji W.ji x.B.ji x.l.ji Y.Y.ji x.Q.jia Z.K.jia D.jiang H.B.jiang P.C.jiang S.S.jiang T.j.jiang x.S.jiang Y.jiang j.B.jiao j.K.jiao Z.jiao S.jin Y.jin M.Q.jing x.M.jing T.johansson S.Kabana N.Kalantar-Nayestanaki x.l.Kang x.S.Kang M.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf M.Kuessner x.Kui N.Kumar A.Kupsc W.Kühn j.j.lane P.larin l.lavezzi T.T.lei Z.H.lei M.lellmann T.lenz C.li C.li C.H.li Cheng li D.M.li F.li G.li H.B.li H.j.li H.N.li Hui li j.R.li j.S.li Ke li l.j.li l.K.li lei li M.H.li P.R.li Q.M.li Q.x.li R.li S.x.li T.li W.D.li W.G.li x.li x.H.li x.l.li x.Z.li xi Institute of High Energy Physics Beijing 100049China Beihang university Beijing 100191China Bochum Ruhr-university D-44780BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon university PittsburghPennsylvania 15213USA Central China Normal university Wuhan 430079China Central South university Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China university of Geosciences Wuhan 430074China Chung-Ang university Seoul06974Republic of Korea COMSATS university Islamabad Lahore CampusDefence RoadOff Raiwind Road54000LahorePakistan Fudan university Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291DarmstadtGermany Guangxi Normal university Guilin 541004China Guangxi university Nanning 530004China Hangzhou Normal university Hangzhou 310036China Hebei university Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099MainzGermany Henan Normal university Xinxiang 453007China Henan university Kaifeng 475004China Henan university of Science and Technology Luoyang 471003China Henan university of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal university Changsha 410081China Hunan university Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana university BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati (A)INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara (A)INFN Sezione di FerraraI-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Inner Mongolia university Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de Alta Investigación Universidad de TarapacáCasilla 7DArica 1000000Chile jilin university Changchun 130012China joha

The number ofψ(3686)events collected by the BESⅢdetector during the 2021 run period is determined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadronic *** uncertainty is systematic and the statistical uncertainty is ***,the numbers ofψ(3686)events collected during the 2009 and 2012run periods are updated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,*** numbers are consistent with the previous measurements within one standard *** total number ofψ(3686)events in the three data samples is(2712.4±14.3)×10~6.

关键词： ψ(3686) inclusive process Hadronic events BESⅢdetector

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Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael j.lee Ryota l.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

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Comparative analysis of microstructure,mechanical,and corrosion properties of biodegradable Mg-3Y alloy prepared by selective laser melting and spark plasma sintering

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journal of Magnesium and Alloys 2024年第4期12卷 1496-1510页

作者： P.Minárik M.Zemková S.Šašek j.Dittrich M.Knapek F.lukáˇc D.Koutný j.jaroš R.Král Faculty of Mathematics and Physics Charles UniversityKe Karlovu 5Praha 12116Czech Republic Research Centre University ofŽilinaUniverzitná8215/1Žilina 01026Slovakia Institute of Plasma Physics of the Czech Academy of Sciences Za Slovankou 1782/318200 Praha 8Czech Republic Institute of Machine and Industrial Design Brno University of TechnologyTechnická2896/2Brno 61669Czech Republic

This work explored possibilities of biodegradable magnesium alloy Mg-3Y preparation by two modern powder metallurgy techniques–spark plasma sintering(SPS)and selective laser melting(SlM).The powder material was consolidated by both methods utilising optimised parameters,which led to very low porosity(∼0.3%)in the SlM material and unmeasurably low porosity in the SPS *** main aim of the study was the thorough microstructure characterisation and interrelation between the microstructure and the functional properties,such as mechanical strength,deformability,and corrosion *** materials showed comparable strength of∼110 MPa in tension and compression and relatively good deformability of∼9%and∼21%for the SlM and SPS materials,*** corrosion resistance of the SPS material in 0.1 M NaCl solution was superior to the SlM one and comparable to the conventional extruded *** digital image correlation during loading and the cross-section analysis of the corrosion layers revealed that the residual porosity and large strained grains have the dominant negative effect on the functional properties of the SlM *** the other hand,one of the primary outcomes of this study is that the SPS consolidation method is very effective in the preparation of the W3 biodegradable alloy,resulting in material with convenient mechanical and degradation properties that might find practical applications.

关键词： Magnesium Yttrium Powder metallurgy Microstructure Mechanical strength Corrosion resistance

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An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs

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Bio-Design and Manufacturing 2024年第3期7卷 240-261页

作者： Seol-Ha jeong jarno Hiemstra Patrick V.Blokzijl Rebeca Damian-Ferrara Danilo Martins dos Santos jéssica H.l.da Fonseca Min-Ho Kang jihyun Kim Dilara Yilmaz-Aykut Mei l.l.Cham-Pérez jeroen leijten Su Ryon Shin Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA leijten lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nanotechnology National laboratory for Agriculture(lNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Department of Biomedical-Chemical Engineering The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Department of Biotechnology The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural *** in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted *** oxygen-releasing biomaterials,such as oxygen-generating microparticles(OMPs),have shown promise for enhancing the oxygen supply of microenvironments in injured tissues,whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain *** study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine colloidal-based microgels with *** report that incorporating nanosized calcium peroxide(nCaO_(2))and manganese oxide nanosheets(nMnO_(2))into hydrophobic polymeric microparticles enables precise modulation of oxygen release while controlling hydrogen peroxide ***,the fabrication of oxygenating and cytocompatible colloidal gels is achieved using an aqueous two-phase *** study thoroughly evaluates the fundamental characteristics of the resulting bioink,including its rheological behaviors,printability,shape fidelity,mechanical properties,and oxygen release ***,this study demonstrates the macroscopic scalability and cytocompatibility of printed constructs produced via cell-laden oxygenating colloidal *** showcasing the effectiveness of extrusion-based bioprinting,this study underscores how it can be used to fabricate biomimetic tissues,indicating its potential for new *** findings presented here advance the bioprinting field by achieving scalability with both high cell viability and the possibility of mimicking specifically oxygenated *** work thereby offers a promising avenue for the development of functional tissues with e

关键词： 3D bioprinting Bioink Colloidal gels Extrusion printing Oxygen-generating microparticle

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Modelling dynamic pantograph loads with combined numerical analysis

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Railway Engineering Science 2024年第1期32卷 81-94页

作者： F.F.jackson R.Mishra j.M.Rebelo j.Santos P.Antunes j.Pombo H.Magalhaes l.Wills M.Askill School of Computing and Engineering University of HuddersfieldHuddersfieldUK School of Computing and Engineering Institute of Railway ResearchUniversity of HuddersfieldHuddersfieldUK IDMEC Instituto Superior TecnicoUniversidade de LisboaLisbonPortugal ISEl Instituto Politecnico de LisboaLisbonPortugal Hitachi Rail Newton AycliffeUK Wabtec/Brecknell Willis ChardUK

Appropriate interaction between pantograph and catenary is imperative for smooth operation of electric *** heights of overhead lines to accommodate level crossings,overbridges,and tunnels pose significant challenges in maintaining consistent current collection performance as the pantograph aerodynamic profile,and thus aerodynamic load changes significantly with operational *** research aims to analyse the global flow characteristics and aerodynamic forces acting on individual components of an HSx pantograph operating in different configurations and orientations,such that the results can be combined with multibody simulations to obtain accurate dynamic insight into contact ***,computational fluid dynamics simulations are used to investigate the pantograph component loads in a representative setting,such as that of the recessed cavity on a Class 800 *** an aerodynamic perspective,this study indicates that the total drag force acting on non-fixed components of the pantograph is larger for the knuckle-leading orientation rather than the knuckle-trailing,although the difference between the two is found to reduce with increasing pantograph *** the aerodynamic loads acting on individual components with multibody tools allows for realistic dynamic insight into the pantograph *** results obtained show how considering aerodynamic forces enhance the realism of the models,leading to behaviour of the pantograph-catenary contact forces closely matching that seen in experimental tests.

关键词： Pantograph-catenary interaction Pantograph aerodynamics Computational fluid dynamics Pantograph loads Current collection performance

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由超拍电子伏特加速器产生的超高能伽马射线气泡

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Science Bulletin 2024年第4期69卷 449-457页

作者： lHAASO Collaboration Zhen Cao Chuandong Gao Cong li Ruo-Yu liu Ruizhi Yang 不详 Key laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China university of Chinese Academy of Sciences Beijing 100049China TIANFu Cosmic Ray Research Center ChengduChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China university of Science and Technology of China Hefei 230026China

We report the detection of aγ-ray bubble spanning at least 100deg2 in ultra-high energy(uHE)up to a few PeV in the direction of the star-forming region Cygnus x,implying the presence super PeVatron(s)accelerating protons to at least 10 PeV.A log-parabola form with the photon indexΓ(E)=(2.71±0.02)+(0.11±0.02)×log10(E/10 TeV)is found fitting the gamma-ray energy spectrum of the bubble *** sources,“hot spots”correlated with very massive molecular clouds,and a quasi-spherical amorphousγ-ray emitter with a sharp central brightening are observed in the *** the core of~0.5°,spatially associating with a region containing massive OB association(Cygnus OB2)and a microquasar(Cygnus x-3),as well as previously reported multi-TeV sources,an enhanced concentration of uHEγ-rays is observed with 2 photons at energies above 1 *** general feature of the bubble,the morphology,and the energy spectrum,are reasonably reproduced by the assumption of a particle accelerator in the core,continuously injecting protons into the ambient medium.

关键词： Cosmic rays γ-rays Interstellar medium Star cluster

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Impact of device resistances in the performance of graphene‑based terahertz photodetectors

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Frontiers of Optoelectronics 2024年第2期17卷 87-97页

作者： O.Castelló Sofía M.lópez Baptista K.Watanabe T.Taniguchi E.Diez j.E.Velázquez-Pérez Y.M.Meziani j.M.Caridad j.A.Delgado-Notario Department of Applied Physics University of Salamanca37008 SalamancaSpain unidad de Excelencia en luz y Materia Estructurada(luMES) University of Salamanca37008 SalamancaSpain Research Center for Electronic and Optical Materials National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Research Center for Materials Nanoarchitectonics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nanotechnology Group USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In recent years,graphene field-effect-transistors(GFETs)have demonstrated an outstanding potential for terahertz(THz)photodetection due to their fast response and *** features are essential to enable emerging THz applications,including 6G wireless communications,quantum information,bioimaging and ***,the overall performance of these photodetectors may be utterly compromised by the impact of internal resistances presented in the device,so-called access or parasitic *** this work,we provide a detailed study of the influence of internal device resistances in the photoresponse of high-mobility dual-gate GFET *** dual-gate architectures allow us to fine tune(decrease)the internal resistance of the device by an order of magnitude and consequently demonstrate an improved responsivity and noise-equivalent-power values of the photodetector,*** results can be well understood by a series resistance model,as shown by the excellent agreement found between the experimental data and theoretical *** findings are therefore relevant to understand and improve the overall performance of existing high-mobility graphene photodetectors.

关键词： Graphene THz Photodetector Field-effect transistor Plasmonic

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