检索结果-南通市图书馆

World journal of Cardiovascular Surgery 2012年第3期2卷 29-39页

作者： michel R Hoenig jason jenkins Nicholas Boyne Allan Kruger Philip j Walker Department of Vascular Surgery Royal Brisbane & Women’s Hospital Herston Queensland Australia University of Queensland School of Medicine Discipline of Surgery Centre for Clinical Research Herston Queensland Australia

Objectives: To describe thoracic endovascular aortic repair (TEVAR) outcomes at the Royal Brisbane and Women’s Hospital between 2001-2010. Design: Prospective cohort study. Results: We successfully treated 95 of 97 patients for a 98% procedural success rate. Of the treated patients, 68 (72%) were males and mean age was 61 ± 17 years. Average follow up was 3.6 ± 2.0 years. Pathologies treated were: dissection (n = 35), aneurysmal disease (n = 32), traumatic disease (n = 19), coarctation (n = 5) and miscellaneous (n = 4). There was one peri-procedural myocardial infarction. Renal complications occurred in 7 patients (3 with doubling creatinine and 4 requiring temporary renal replacement therapy). Stroke occurred in 2 patients and paresis in 2 patients (permanent in one). Six patients died during index hospitalization and 17 deaths occurred during follow-up, 2 of which were confirmed secondary to aortic pathology. Age (HR 1.08 per year, p < 0.01) and ASA class (HR 2.2 per class, p = 0.02) were independently associated with mortality. There were 25 re-interventions in 22 patients. Eighteen of these re-interventions in 16 patients were related to the management of complications of TEVAR of which 13 were for endoleaks;eight type I, four type II, one type III. Conclusion: TEVAR can be used to treat thoracic aortic pathology but questions remain regarding long-term durability.

关键词： Aorta Stents Surgery

Influence of the operating temperature on the ageing and interfaces of double layer polymer electrolyte solid state Li metal batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第6期16卷 8377-8384页

作者： Mikel Arrese-Igor María Martinez-Ibañez Ander Orue Ekaterina Pavlenko Erwan Dumont michel Armand Frédéric Aguesse Pedro López Aranguren Centre for Cooperative Research on Alternative Energies(CIC energiGUNE) Basque Research and Technology Alliance(BRTA)Alava Technology ParkAlbert Einstein 48Vitoria-Gasteiz 01510Spain University of the Basque Country(UPV/EHU) Barrio Sarrienas/nLeioa 48940Spain Saft 111 Boulevard Alfred DaneyBordeaux Cedex 33074France

Solid-state lithium metal batteries(SSLMBs)are considered an auspicious technology to develop high energy density and safe energy storage *** double layer polymer electrolyte(DLPE)is a rational approach for engineering high-performance SSLMBs addressing electrolyte requirements with specifically designed polymers at the positive electrode and as *** this work,SSLMBs were assembled with poly(propylene carbonate)(PPC),offering stability toward oxidation at the positive electrode,and a gel polymer electrolyte with polyethyleneglycol dimethylether(PEGDME)as separator,offering high ionic conductivity at low temperature and sufficient interfacial stability with Li *** electrochemical properties and performance of cells with LiFePO_(4) and Li[Ni_(0.6)Mn_(0.2)Co_(0.2)]O_(2) positive electrodes are thoroughly investigated as function of the operating temperature by using a host of characterization ***-voltage cells with an areal capacity of 0.7 mAh·cm^(−2)cycled at 40℃ exhibit a higher capacity retention than the cells cycled at 70℃.To understand such differences,a three-electrode setup is applied to discriminate anodic processes from cathodic as function of the *** elucidate the ageing and interfacial evolution for DLPE cells with gel polymer electrolytes paving the way for building performance solid state batteries.

关键词： double layer polymer electrolyte solid-state lithium metal battery gel polymer electrolyte high voltage interfacial study

Endoscopy-based management decreases the risk of postoperative recurrences in Crohn's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2016年第21期22卷 5068-5078页

作者： Anne-Laure Boucher Bruno Pereira Stéphanie Decousus Marion Goutte Felix Goutorbe Anne Dubois johan Gagniere Corinne Borderon juliette joubert Denis Pezet michel Dapoigny Pierre j Déchelotte Gilles Bommelaer Anthony Buisson Gastroenterology Department University Hospital Estaing 63000 Clermont-Ferrand France DRCI Biostatistics Unit GM Clermont-Ferrand University and Medical Center 63000 Clermont-Ferrand France Pathology Department University Hospital Estaing 63000 Clermont-Ferrand France Microbes Intestine Inflammation and Susceptibility of the Host UMR 1071 Inserm/Universite d'Auvergne USC-INRA 2018 63000 Clermont-Ferrand France Digestive Surgery Department University Hospital Estaing 63000 Clermont-Ferrand France Pediatrics Department University Hospital Estaing 63000 Clermont-Ferrand France

AIM: To investigate whether an endoscopy-based management could prevent the long-term risk of postoperative ***: From the pathology department database, we retrospectively retrieved the data of all the patients operated on for Crohn’s disease (CD) in our center (1986-2015). Endoscopy-based management was defined as systematic postoperative colonoscopy (median time after surgery = 9.5 mo) in patients with no clinical postoperative recurrence at the time of ***: From 205 patients who underwent surgery, 161 patients (follow-up > 6 mo) were included. Endoscopic postoperative recurrence occurred in 67.6%, 79.7%, and 95.5% of the patients, respectively 5, 10 and 20 years after surgery. The rate of clinical postoperative recurrence was 61.4%, 75.9%, and 92.5% at 5, 10 and 20 years, respectively. The rate of surgical postoperative recurrence was 19.0%, 38.9% and 64.7%, respectively, 5, 10 and 20 years after surgery. In multivariate analysis, previous intestinal resection, prior exposure to anti-TNF therapy before surgery, and fistulizing phenotype (B3) were postoperative risk factors. Previous perianal abscess/fistula (other perianal lesions excluded), were predictive of only symptomatic recurrence. In multivariate analysis, an endoscopy-based management (n = 49/161) prevented clinical (HR = 0.4, 95%CI: 0.25-0.66, P < 0.001) and surgical postoperative recurrence (HR = 0.30, 95%CI: 0.13-0.70, P = 0.006).CONCLUSION: Endoscopy-based management should be recommended in all CD patients within the first year after surgery as it highly decreases the long-term risk of clinical recurrence and reoperation.

关键词： Crohn’ s disease Postoperative recurrence Endoscopy Prevalence Risk factors

Variation of Stable Isotopes in Surface Snow along a Traverse from Coast to Plateau's interior in East Antarctica and Its Climatic Significance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Cold and Arid Regions 2009年第1期1卷 14-24页

作者： jean jouzel michel Stievenard Institut Pierre Simon Laplace/Laboratoire des Sciences du Climat et de l'Environnement CEA-CNRS-University Versailles-Saint Quentin

The variations of stable water isotopes of surface snow in east Antarctic Ice Sheet, are discussed by a total of 251 samples, which were taken along a 330 km traverse from Zhongshan Station to the outer edge of the Antarctic plateau and from four snow pits excavated along the route. Analyzing results of the samples showed the expected linear relationship between the parameters ?D and ?18O with slope S1 and intercept d1. When the data set was examined using a sliding window with a width of 5 samples, it was found that there were two areas with different ratios of S1 and d1. The boundary between these two areas occurred at an elevation of about 2,000 m, suggesting two different sources of water vapour. Nearly half (47%) of the fresh-snow samples had negative deuterium excess (d=?D? 8?18O) values, but few of the snow pit samples did, suggesting that variations of ? are quickly smoothed by isotopic diffusion in the near-surface firn. Analysis of the phase relationship between ?D and deuterium excess in the snow pit stratigraphies showed that they were mostly in phase from jan. 1994 to Sept. 1995, but mostly out of phase from Sept. 1995 to jan. 1997.

关键词： east Antarctica ice sheet stable isotopes snow

Mediator contributes to IgH locus VDj rearrangements by promoting usage of most distal V segments

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2020年第4期17卷 407-409页

作者： Iman Dalloul Zeinab Dalloul Sandrine Le Noir François Boyer Bernardo Reina-San-Martin jeanne Cook-Moreau michel Cogné UMR CNRS 7276 INSERM U1262Universite de LimogesLimoges 87025France INSERM U1258 UMR CNRS 7104Institut de Genetique et de Biologie Moleculaire et CellulaireUniversitéde StrasbourgIllkirch 67400France

INTRODUCTION The immunoglobulin heavy(IgH)chain locus includes a large cluster of V,D and j segments spanning thousands of kilobases in mammals and its expression implies long-range 3D-regulation of various gene modifications.1 V(D)j recombination occurs during early B-cell ontogeny.2 It is regulated by multiple transcription factors and cis-regulatory elements,and most notably by the intronic 5′Eμelement located in the jH to Cμintron.3 The intergenic control region 1(IGCR1)located between the VH and D gene clusters inhibits rearrangement of the most DH-proximal VH gene segments,while promoting usage of distal VH gene segments.4 Other downstream elements of the locus,flanking its 3′end might have more subtle roles:while the large 3′regulatory region(3′RR)shows strong internal synergies2 and behaves as a superenhancer in mature B *** deletion showed no influence on the VDj repertoire and rather increased transcription of unrearranged V segments.3–5 Insulators binding CTCF farther downstream of the 3′RR were shown,however,to promote usage of distal VH segments.6 Altogether,there are strong indications that elements involved in long-distance regulation of transcription might also influence VDj ***-frame splicing of VDj exons is also needed for full Ig expression.7 Given the functional importance of gene architecture and long-range interactions for the IgH locus physiology,we explored the dependence of the VDj repertoire on Med1,a known actor of long-range enhancer interactions.

关键词： B cells mediator VDj repertoire

A positron source using an axially oriented crystal associated to a granular amorphous converter

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics C 2012年第9期36卷 871-878页

作者：徐成海 Robert Chehab Peter Sievers Xavier Artru michel Chevallier Olivier Dadoun 裴国玺 Vladimir M.Strakhovenko Alessandro Variola Institute of High Energy Physics Chinese Academy of Sciences Laboratoire de l'Accélérateur Linéaire IN2P3/CNRS et Université de Paris-SudBP 34-91898Orsay cedexFrance Institut de Physique Nucléaire de Lyon IN2P3/CNRS et Université Lyon 169622 VilleurbanneFrance CERN CH-1211Genéve 23Switzerland Budker Institute of Nuclear Physics Av.Lavrentyeva11630090 NovosibirskRussia

A non-conventional positron source using the intense y radiation from an axially oriented monocrys- tal which materializes into e^＋e^- pairs in a granular amorphous converter is described. The enhancement of photon radiation by multi-GeV electrons crossing a tungsten crystal along its 〈111〉 axis is reported. The resulting enhancement of pair production in an amorphous converter placed 2 meters downstream, is also re- ported. Sweeping off the charged particles from the crystal by a bending magnet upstream of the converter allows a significant reduction of the deposited energy density. Substituting a granular target made of small spheres for the usual compact one, makes the energy dissipation easier. The deposited energy and correspond- ing heating are analyzed and solutions for cooling are proposed. The configurations studied here for this kind of positron source allow its consideration for unpolarized positrons for the ILC.

关键词： channeling effect crystal positron source ILC

月经周期不同阶段游离皮质醇昼夜节律的变化(英文)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

2020年

学校读者我要写书评

暂无评论

生理学报 2003年第5期55卷 547-553页

作者：包爱民刘荣玉 Eus j.W.VanSomeren michel A.Hofman 周江宁中国科学技术大学生命科学学院神经生物学系合肥230032 安徽医科大学第一附属医院安徽省老年病研究所合肥230022 Netherlands Institute for Brain Research 1105 AZ Amsterdam ZOThe Netherlands

为了研究皮质醇分泌的昼夜节律在月经周期中的变化,实验对15位月经周期正常的育龄期健康妇女,在月经周期的不同阶段分别于24h内每隔两小时采样,检测唾液昼夜游离皮质醇水平。采用非线性回归分析模型分析皮质醇昼夜节律。结果显示,皮质... 详细信息

为了研究皮质醇分泌的昼夜节律在月经周期中的变化,实验对15位月经周期正常的育龄期健康妇女,在月经周期的不同阶段分别于24h内每隔两小时采样,检测唾液昼夜游离皮质醇水平。采用非线性回归分析模型分析皮质醇昼夜节律。结果显示,皮质醇昼夜节律在整个月经周期都具有复杂的明显受到亚节律(ultradian)影响的分泌形式;与月经期相比,围排卵期和黄体晚期昼夜节律波峰宽度(peak-width)明显减低(P=0.005与 0.031),而昼夜节律波谷(trough)有抬高趋势(P=0.0622与0.066);黄体晚期的亚节律波幅(ultradian amplitude)与月经期相比显著减低(P=0.002)而与围排卵期相比有减低趋势(P= 0.05)。这些结果提示月经周期的不同阶段对皮质醇分泌的昼夜节律有影响。

关键词：昼夜节律亚节律游离皮质醇月经周期唾液

Nano-fried-eggs： Structural, optical, and magnetic characterization of physically prepared iron-silver nanoparticles

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nano Research 2018年第11期11卷 6074-6085页

作者： julien Ramade Nicolas Troc Olivier Boisron michel Pellarin Marie-Ange Lebault Emmanuel Cottancin Vitor T. A. Oiko Rafael Cabreira Gomes Varlei Rodrigues Matthias Hillenkamp Univ. Lyon Universitd Claude Bernard Lyon I CNRS UMR5306 Institut Lumiee Matiee t=-69622 Villeurbanne France Instituto de F[sica Gleb Wataghin UNICAMP CP 6165 13083-970 Campinas SP Brazil

The prospect of combining both magnetic and plasmonic properties in a single nanoparticle promises both valuable insights on the properties of such systems from a fundamental viewpoint and numerous possibilities for technological applications. However, the combination of two of the most prominent metallic candidates—iron and silver—has presented numerous experimental difficulties because their thermodynamic properties impede miscibility and even coalescence. Herein, we present the thorough characterization of physically prepared Fe50Ag50 nanoparticles embedded in carbon and silica matrices via electron microscopy, optical spectroscopy, magnetometry and synchrotron-based X-ray spectroscopy. Iron and silver segregate completely into structures resembling fried eggs, with a nearly spherical, crystallized silver part surrounded by an amorphous structure of iron carbide or oxide, depending on the environment of the particles. Consequently, the particles exhibit both plasmonic absorption corresponding to the silver nanospheres in an oxide environment and a reduced but measurable magnetic response. The suitability of such nanoparticles for technological applications is discussed from the viewpoint of their high chemical reactivity with their environment.

关键词： nanoalloy bimetallic nanoparticles iron silver FeAg optical spectroscopy magnetometry

Giant hepatic extra-gastrointestinal stromal tumor treated with cytoreductive surgery and adjuvant systemic therapy:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Gastrointestinal Surgery 2021年第3期13卷 315-322页

作者： michel Ribeiro Fernandes Caroline Lorenzoni Almeida Ghezzi Tomaz j M Grezzana-Filho Flávia Heinz Feier Ian Leipnitz Aljamir Duarte Chedid Carlos Thadeu Schmidt Cerski Marcio Fernandes Chedid Cléber RositoPinto Kruel Department of Gastrointestinal Surgery and Transplantation Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007RSBrazil Division of Radiology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903RSBrazil Department of Pathology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007RSBrazil

BACKGROUND Primary extra-gastrointestinal stromal tumors(E-GIST)of the liver are *** clinical presentation may range from asymptomatic to bleeding or manifestations of mass *** surgery followed by adjuvant therapy with imatinib is the standard of ***,under specific circumstances,a cytoreductive approach may represent a therapeutic *** describe herein the case of an 84-year-old woman who presented with a tender,protruding epigastric *** computed tomography scan revealed a large,heterogeneous mass located across segments III,IV,V,and VIII of the *** initial approach was transarterial embolization of the tumor,which elicited no appreciable *** the large size and central location of the tumor and the advanced age of the patient,non-anatomic complete resection was *** to substantial intraoperative bleeding and hemodynamic instability,only a near-complete resection could be *** and immunohistochemical staining confirmed the diagnosis of primary E-GIST of the *** the risk/benefit ratio for therapeutic options,debulking surgery may represent a strategy to control pain and prolong *** SUMMARY Here,we present a case report of a patient diagnosed with E-GIST primary of the liver,which was indicated a cytoreductive surgery and adjuvant therapy with *** E-GIST primary of the liver is a rare conditional,the treatment is with systemic therapy and total resection ***,a cytoreductive surgery will be necessary when a complete resection is no possible.

关键词： Extra-gastrointestinal stromal tumor Primary gastrointestinal stromal tumor of the liver Cytoreductive surgery Debulking surgery Case report