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journal of Environmental Sciences 2024年第4期138卷 350-372页

作者： Zhuo Wei YiWei Yang Liu Shuai Niu Yaxi Xu jong-Hwan Park jim j.Wang Faculty of Environmental Science&Engineering Kunming University of Science&TechnologyKunming 650500China School of Plant Environment&Soil SciencesLouisiana State University AgCenter.Baton RougeLA 70803USA Department of Life Resources Industry Dong-A University37Nakdong-daero 550 beon-gilSaha-guBusan 49315South Korea

Petroleum contamination is considered as a major risk to the health of humans and *** as low-cost and eco-friendly carbon materials,have been widely used for the removal of petroleum hydrocarbon in the *** purpose of this paper is to review the performance,mechanisms,and potential environmental toxicity of biochar,modified biochar and its integration use with other materials in petroleum contaminated soil and ***,the use of biochar in oil-contaminated water and soil as well as the factors that could influence the removal ability of biochar were systematically *** addition,the modification and integrated use of biochar for improving the removal efficiency were summarized from the aspects of sorption,biodegradation,chemical degradation,and ***,the functional impacts and associated ecotoxicity of pristine and modified biochars in various environments were ***,some shortcoming of current approaches,and future research needs were provided for the future direction and challenges of modified biochar ***,this paper gain insight into biochar application in petroleum remediation from the perspectives of performance enhancement and environmental sustainability.

关键词： Petroleum contamination Adsorbent Bioremediation Biochar modification Ecotoxicity

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Corrosion testing of X52 and X80 steels immersed in stimulated emulsions using a real petroleum sample

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Petroleum Research 2024年第2期9卷 304-316页

作者： L.M.Quej-Ake j.L.Alamilla A.Contreras Instituto Mexicano del Petróleo Eje Central Lázaro CárdenasNorte 152San Bartolo AtepehuacanGustavo A.MaderoCiudad de MéxicoC.P.07730México

The aim of this study is to evaluate the internal corrosion process on X52 and X80 steels/real petroleum interfaces containing condensed hydrocarbon plus oilfield-produced water,which were subjected to stimulated emulsions using 50/50 vol ratio mixtures at 45℃,different hydrodynamic conditions,1 h,and 24 h.A washing process by using deionized water was proposed to simulate and identify the corrosiveness of the hydrocarbon phase after 24 h of exposure *** characterization by electrochemical impedance spectroscopy and the monitoring of the polarization curves indicated that X80 steel/oilfield-produced water interfaces were more susceptible to corrosion than X52 steel exposed to oilfield-produced *** combined speed rotation of 600 rpm using a magnetic stirrer+600 rpm using a rotating disk electrode decreased the corrosion rate on X52 *** stimulated emulsions made of hydrocarbon+oilfield-produced water and hydrocarbon+deionized water at 24 h increased the corrosion rate on X80 steel(0.34 mm/year and 0.43 mm/year,respectively),promoting the formation of erosion and pitting *** types of corrosion depended mainly on the physicochemical properties of the hydrocarbon,oilfield-produced water,exposure times,and hydrodynamic systems in which the hydrocarbon was studied.

关键词： Corrosion Emulsions X52 steel X80 steel

The Meat of the Matter: Plant-Based Meat Analogue versus Traditional Meat Product Nutritional Quality

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Food Science and Human Wellness 2024年

作者： Arshia Shireen Amanda j Wright Department of Human Health and Nutritional Sciences University of Guelph Guelph Ontario Canada bDepartment of Human Health and Nutritional Sciences University of Guelph Guelph Ontario Canada

Plant-based meat analogues (PBMA) are formulated to mimic the sensory characteristics of traditional meat products (TMP) using vegetarian ingredients and are increasingly popular with the trend towards plant-based diets， even among meat-eating consumers. This narrative review compared the nutritional quality of PBMA and TMP to broaden the discussion on the suitability of simulated meat products to substitute TMP， while exploring other attributes for their comparison. The complexity of PBMA and TMP means they are not entirely interchangeable. Importantly， PBMA health effects extend beyond their basic nutrient content and quality. Postprandial metabolism and satiety， for example， can be affected by product formulation， ingredient interactions， and thermomechanical processing involved in producing organoleptically acceptable PBMA. There are specific opportunities for low-sodium PBMA products to contribute to a healthy shift toward plant-based diets. In conclusion， PBMA cannot be assumed to be healthier than TMP. They should be designed with comprehensive consideration of composition and processing to ensure they support consumers who are adopting plant-based diets in realizing the theoretical health benefits.

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Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael j.Lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

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Classical bovine spongiform encephalopathy and chronic wasting disease:two sides of the prion coin

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Animal Diseases 2024年第1期4卷 1-18页

作者： Nicholas j.Haley juergen A.Richt Department of Microbiology and Immunology College of Graduate StudiesMidwestern UniversityGlendaleAZUSA Department of Diagnostic Medicine/Pathobiology College of Veterinary MedicineKansas State UniversityManhattanKSUSA

Transmissible spongiform encephalopathies(TSEs)are a group of progressive and ultimately fatal neurologic diseases of man and animals,all resulting from the propagated misfolding of the host's normal cellular prion *** diseases can be spontaneous,heritable,anthropogenic/iatrogenic,or in some cases horizontally transmissible,and include such notable TSEs as bovine spongiform encephalopathy(BSE)of cattle and chronic wasting disease(CWD)of *** they are both unequivocally protein misfolding disorders,they differ markedly in their pathogenesis,transmissibility,and zoonotic *** the BSE epidemic has largely abated over the past three decades following global feed bans on ruminant meat and bone meal,CWD,which is readily transmitted through various forms of excreta,has rapidly expanded from its original endemic zone to encompass much of North America,along with recently identified foci in *** importantly,although the classical form of BSE has proven transmissible to humans consuming contaminated beef or beef products,so far there have been no conclusive reports on the zoonotic transmission of cWD to *** underlying basis for these differences-whether host or agent directed-are not well understood,though may be due to inherent differences in the three-dimensional structure of the misfolded BSE or CWD prion proteins or the expression levels and tissue distribution of respective cellular prion *** the uncontrolled geographic spread of CWD,it is imperative that we improve our understanding of the factors governing prion disease pathogenesis,transmission,and zoonotic potential.

关键词： Prion Bovine Spongiform Encephalopathy Chronic Wasting Disease Transmission Pathogenesis Zoonosis

Threshold-Based Software-Defined Networking(SDN)Solution for Healthcare Systems against Intrusion Attacks

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1469-1483页

作者： Laila M.Halman Mohammed j.F.Alenazi Department of Computer Engineering College of Computer ScienceKing Saud UniversityRiyadh11451Saudi Arabia

The healthcare sector holds valuable and sensitive *** amount of this data and the need to handle,exchange,and protect it,has been increasing at a fast *** to their nature,software-defined networks(SDNs)are widely used in healthcare systems,as they ensure effective resource utilization,safety,great network management,and *** this sector,due to the value of thedata,SDNs faceamajor challengeposed byawide range of attacks,such as distributed denial of service(DDoS)and probe *** attacks reduce network performance,causing the degradation of different key performance indicators(KPIs)or,in the worst cases,a network failure which can threaten human *** can be significant,especially with the current expansion of portable healthcare that supports mobile and wireless devices for what is called mobile health,or *** this study,we examine the effectiveness of using SDNs for defense against DDoS,as well as their effects on different network KPIs under various *** propose a threshold-based DDoS classifier(TBDC)technique to classify DDoS attacks in healthcare SDNs,aiming to block traffic considered a hazard in the form of a DDoS *** then evaluate the accuracy and performance of the proposed TBDC *** technique shows outstanding performance,increasing the mean throughput by 190.3%,reducing the mean delay by 95%,and reducing packet loss by 99.7%relative to normal,with DDoS attack traffic.

关键词： Network resilience network management attack prediction software defined networking(SDN) distributed denial of service(DDoS) healthcare

A marathon,not a sprint:Increasing population physical activity as a legacy of sports mega-events

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journal of Sport and Health Science 2024年第6期13卷 732-735页

作者： Fiona C.Bull Paul j.Simpson Physical Activity Unit Department of Health PromotionWorld Health OrganizationGeneva CH-1211Switzerland The BMj London WC1H 9JPUK

*** matters The withdrawal of Australia as hosts for the Commonwealth Games in 2026 demonstrates that large international sporting events are more than just sporting mastery,medals,and *** also matters.1 The cost of hosting a major international tournament is eye-wateringly *** governments need to show that the billions of dollars of investment deliver a return beyond sporting glory to justify the resources that are spent.

关键词： return dollar sport

Precise genome-editing in human diseases:mechanisms,strategies and applications

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1065-1085页

作者： Yanjiang Zheng Yifei Li Kaiyu Zhou Tiange Li Nathan j.VanDusen Yimin Hua Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE Department of PediatricsWest China Second University HospitalSichuan UniversityChengduSichuan 610041China Department of Cardiovascular Surgery West China HospitalSichuan UniversityChengduSichuan 610041China Department of Pediatrics Herman B Wells Center for Pediatric ResearchIndiana University School of MedicineIndianapolisIN 46202USA

Precise genome-editing platforms are versatile tools for generating specific,site-directed DNA insertions,deletions,and *** continuous enhancement of these tools has led to a revolution in the life sciences,which promises to deliver novel therapies for genetic *** genome-editing can be traced back to the 1950s with the discovery of DNA’s doublehelix and,after 70 years of development,has evolved from crude in vitro applications to a wide range of sophisticated capabilities,including in vivo ***,precise genome-editing faces constraints such as modest efficiency,delivery challenges,and off-target *** this review,we explore precise genome-editing,with a focus on introduction of the landmark events in its history,various platforms,delivery systems,and ***,we discuss the landmark events in the history of precise ***,we describe the current state of precise genome-editing strategies and explain how these techniques offer unprecedented precision and versatility for modifying the human ***,we introduce the current delivery systems used to deploy precise genome-editing components through DNA,RNA,and ***,we summarize the current applications of precise genome-editing in labeling endogenous genes,screening genetic variants,molecular recording,generating disease models,and gene therapy,including ex vivo therapy and in vivo therapy,and discuss potential future advances.

关键词： precise generating editing

Differential colour-ring loss among Dalmatian Pelican(Pelecanus crispus) colonies and its consequence on survival estimates

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Avian Research 2024年第1期15卷 66-71页

作者： Anastasios Bounas Giorgos Catsadorakis Dionyssia Hatzilacou Theodoros Naziridis jocelyn Champagnon Alain j.Crivelli Department of Biological Applications and Technology University of IoanninaIoanninaGreece Society for the Protection of Prespa Agios GermanosGreece Natural Environment and Climate Change Agency 207 Mesogeion Ave.11525AthensGreece Natural Environment and Climate Change Agency Kerkini BranchKerkiniGR-62055Kato PoroiaGreece Tour du Valat Research Institute for Conservation of Mediterranean Wetlands13200ArlesFrance

The analysis of bird ringing data often comes with some potential sources of error and bias,as ring wear and/or loss could affect mark-recapture analyses and produce erroneous estimates of ***,ring wear and loss rates may differ between and within species based on the habitat they use or the species’ life-history traits and behaviour as well as the type of the *** this study we use resighting data from a long-term double marking experiment to directly estimate the rate of colour-ring loss among different Dalmatian Pelican colonies over time,evaluate any possible factors that could contribute to differential ring loss and assess how it may bias the results of mark-resighting *** on 14,849 resightings from 1275 individuals and using multi-state continuous-time hidden Markov models(HMMs) we showed that probability of ring loss was markedly different among colonies,ranging from 0.10 to 0.42 within the first year of marking,whereas the cumulative probability of losing a ring after ten years ranged 0.64 to *** rates are among the highest estimated when compared to previous studies in *** approach assessing the intra-specific variance in ring loss provided several factors potentially involved,such as the use of glue and the fledgling age accuracy and we could further hypothesise the effect of environmental ***,our results showed that ring loss can be a significant challenge for the assessment of the species’ population dynamics using mark-recapture methods as survival was consistently underestimated when not accounting for ring loss and varied significantly among different colonies.

关键词： Bias Capture-mark-recapture Colour-ring Double-marking Hidden Markov models

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Physical activity with or without dietary intervention for the prevention of cardiovascular diseases

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journal of Sport and Health Science 2024年第6期13卷 753-755页

作者： Carl j.Lavie Salvatore Carbone Leandro Slipczuk The john Ochsner Heart and Vascular Institute Ochsner Clinical Schoolthe University of Queensland School of MedicineNew OrleansLA 70121USA Department of Kinesiology and Health Sciences College of Humanities and SciencesVirginia Commonwealth UniversityRichmondVA 23284USA Montefiore Health System/Albert Einstein College of Medicine BronxNY 10461USA

We and others have published extensively on the benefits of physical activity(PA),exercise training,and cardiorespiratory fitness(CRF)to decrease the prevalence of cardiovascular diseases(CVDs)and CVD and all-cause morbidity and mortality.^(1-5)Both PA and CRF are important;however,CRF,which is mostly obtained through PA,although there is a genetic component,seems to be even more important than PA for predicting prognosis.^(1,4-6)Certainly,the wealth of data from across the world has indicated that increasing PA to enhance CRF while mitigating sedentary behavior would go a long way to lessen the world-wide obesity epidemic and reduce CVD and all-cause mortality.

关键词： mortality prevention diseases