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回顾过去、展望未来:水泥化学的发展

商品混凝土 2009年第5期 15-17页

作者： j.f.young 罗培刘数华美国伊利诺大学香槟分校武汉大学水资源与水电工程科学国家重点实验室武汉430072

水泥化学国际学术会议论文集记载了该领域的重要科学进展,第十二届水泥化学国际学术会议是自1919年以来召开的最近的一次学术会议(表1)。

关键词：会议论文集学术会议展望未来硅酸三钙游离氧化钙硬化水泥浆体硅酸盐熟料胶凝材料活性粉末混

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化学外加剂对C_3S水化的影响

混凝土世界 2011年第12期 34-38页

作者：吴兆琦 j.f.young

一、引言化学外加剂在混凝土工业中的使用已有100多年历史，但是外加剂对水泥水化的作用机理至今仍未完全掌握。1972年young对此作过探讨，并提出了C，S水化机理的模型。以后，Kondo、Daimon和Kantro均在这个领域作过系统研究。

关键词：化学外加剂水泥水化 C3S 水化机理混凝土

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工程师的技术生活在改变中

世界科学 1979年第10期 1-6页

作者： j.f.young L.C.HARRIoTT 陆民德

导言人们只要考虑到以下三个现实,就可以确信工程师们技术生活的改变已经到来了。这三个现实是:一些关键性的外部力量将要影响到技术学和工程学;这些力量将会影响工程领域本身的性质及工程师们的工作环境和责任;还有就是工程师们如不学... 详细信息

导言人们只要考虑到以下三个现实,就可以确信工程师们技术生活的改变已经到来了。这三个现实是:一些关键性的外部力量将要影响到技术学和工程学;这些力量将会影响工程领域本身的性质及工程师们的工作环境和责任;还有就是工程师们如不学会掌握全新的知识、技术、

关键词：领域工程师们工业界

Maximizing biomass utilization: An integrated strategy for coproducing multiple chemicals

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journal of Energy Chemistry 2025年第1期100卷 180-191页

作者： Byeongchan Ahn Sua jo jonggeol Na j.jay Liu young-ju Kim Wangyun Won Department of Chemical and Biological Engineering Korea University Department of Chemical Engineering (Integrated process) Kyung Hee University Department of Chemical Engineering and Materials Science Ewha Womans University Department of Chemical Engineering Pukyong National University Resources Engineering Plant Research Department Korea Institute of Geoscience and Mineral Resources

Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol（1,6-HDO） with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments（LCAs）.Strategy A was found to be the most favorable both economically（USRDSCHARDOLLAR3,402/ton） and environmentally（-26.9 kg CO2eq.）. This indicates that lignin valorization is not only economically but also environmentally preferred. finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.

关键词： Biorefinery Carbon mitigation Climate change Global warming Lignin utilization Bioeconomy

High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

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Neural Regeneration Research 2025年第1期20卷 107-115页

作者： Hanki Kim Bum jun Kim Seungyon Koh Hyo jin Cho Xuelian jin Byung Gon Kim jun young Choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration

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International Union for Biological Sciences Symposium on Integrative Biology of Reproductive and Social Behaviors

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Integrative Zoology 2007年第1期2卷 36-55页

作者： Larry j young 不详

SRA regulates female meiosis,ovulation and reproductive behavior in Drosophila Toshiro AIGAKI Department of Biology,Tokyo Metropolitan University,Minamiosawa,Tokyo,japan(aigaki-toshiro@***)Mating induces dramatic changes in the reproductive behavior of females in Drosophila *** better understand the genetic bases of post-mating responses in females,we screened a collection of P{GS}insertion lines,and identified sarah(sra),whose misexpression in the nervous system induced high levels of ovulation in *** flies also extruded the ovipositor toward courting males as seen in wild-type mated females,supporting the notion that ovulation and behavioral patterns are physiologically *** sra insertions were found to be hypomorphic alleles with reduced expression levels.

关键词： insertion bases behavior

DESIGN AND IMPLEMENTATION Of REAL-TIME PHYSICS SIMULATION ENGINE fOR e-ENTERTAINMENT

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International journal of Modeling, Simulation, and Scientific Computing 2013年第S1期4卷 20-39页

作者： MYUNGSOO BAE young j.KIM Computer Science and Engineering Ewha Womans University SeoulKorea

We present our recent research results regarding the designing and implementation of real-time physics simulation engines,which aim at developing physics-inspired e-entertainment such as computer games,mobile applications,interactive TV and other smart media in *** real-time physics engine consists of three functional components:rigid body dynamics simulation,deformable body simulation,and data-driven physics *** core simulation techniques to realize these simulation components include real-time collision detection and response,large-scale model simulation,and character model *** this paper,we highlight these features and demonstrate their *** also showcase some of the gaming applications that we have integrated our physics engine into.

关键词： Real-time physics simulation engine rigid body dynamics simulation deformable body simulation data-driven simulation.

Subtypes of functional dyspepsia

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World journal of Gastroenterology 2006年第17期12卷 2667-2671页

作者： Georgina Baker Robert j fraser Graeme young Department of Gastroenterology Repatriation General Hospital and flinders Medical Centre Australia

functional dyspepsia is a common clinical condition characterised by chronic or recurrent upper abdominal pain or discomfort commonly associated with a variety of associated gastrointestinal symptoms and a normal endoscopy. To standardise research-based approaches, an initial categorisation of into sub groups was agreed to, based on clusters of symptoms. However the early expectation that these subgroups would be associated with distinct pathophysiologies amenable to specific therapy has not been realised. A classification based on the most troublesome symptom has been suggested but the utility of this is also unclear. More recent data suggest that some of the pathophysiologic dysfunctions may be associated with specific symptoms and so provide a better tool for grouping patients. But this approach remains incomplete as current insights into the pathogenesis are still too limited for this to be satisfactory. In conclusion, no classification provides for an adequate treatment-based approach to the syndrome of functional dyspepsia. As a consequence treatment remains largely empiric.

关键词： functional dyspepsia Classification Subtypes Symptoms Pathophysiology Management

Hypothesized summative anal physiology score correlates but poorly predicts incontinence severity

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World journal of Gastroenterology 2017年第31期23卷 5732-5738页

作者： Christopher j young Assad Zahid Cherry E Koh jane M young Department of Colorectal Surgery University of Sydney RPAH Medical Centre Discipline of Surgery University of Sydney Surgical Outcome Research Centre(SOu RCe) Royal Prince Alfred HospitalUniversity of Sydney School of Public health University of Sydney

To explore the relationship between such a construct and an existing continence score. METHODSA retrospective study of incontinent patients who underwent anal physiology (AP) was performed. AP results and Cleveland Clinic Continence Scores (CCCS) were extracted. An anal physiology score (APS) was developed using maximum resting pressures (MRP), anal canal length (ACL), internal and external sphincter defects and pudendal terminal motor latency. Univariate associations between each variable, APS and CCCS were assessed. Multiple regression analyses were performed. RESULTSOf 508 (419 women) patients, 311 had both APS and CCCS measured. Average MRP was 51 mmHg (SD 23.2 mmHg) for men and 39 mmHg (19.2 mmHg) for women. functional ACL was 1.7 cm for men and 0.7 cm for women. Univariate analyses demonstrated significant associations between CCCS and MRP (P = 0.0002), ACL (P = 0.0006) and pudendal neuropathy (P ficant (P for only 9.2% of the variability in CCCS. Multiple regression showed that the variables most useful in predicting CCCS were external sphincter defect, pudendal neuropathy and previous pelvic surgery, but only improving the scores predictive ability to 12.5%. CONCLUSIONThis study shows that the ability of AP tests to predict continence scores improves when considered collectively, but that a constructed summation model before and after multiple regression is poor at predicting the variability in continence scores.

关键词： Incontinence Anal physiology Anal canal Anal ultrasound Manometry Electromyography