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Chinese Physics C 2016年第10期40卷 132-348页

作者： C.Patrignani K.Agashe G.Aielli C.Amsler M.Antonelli D.M.Asner H.Baer Sw.Banerjee R.M.Barnett T.Basaglia C.W.Bauer j.j.Beatty V.I.Belousov j.Beringer S.Bethke H.Bichsel O.Biebel E.Blucher G.Brooijmans O.Buchmueller V.Burkert M.A.Bychkov R.N.Cahn M.Carena A.Ceccucci A.Cerri D.Chakraborty M.-C.Chen R.S.Chivukula K.Copic G.Cowan O.Dahl G.D'Ambrosio T.Damour D.de Florian A.de Gouvea T.DeGrand P.de jong G.Dissertori B.A.Dobrescu M.D'Onofrio M.Doser M.Drees H.K.Dreiner D.A.Dwyer P.Eerola S.Eidelman j.ellis j.Erler V.V.Ezhela W.Fetscher B.D.Fields B.Foster A.Freitas H.Gallagher L.Garren H.-j.Gerber G.Gerbier T.Gershon T.Gherghetta A.A.Godizov M.Goodman C.Grab A.V.Gritsan C.Grojean D.E.Groom M.Grnewald A.Gurtu T.Gutsche H.E.Haber K.Hagiwara C.Hanhart S.Hashimoto Y.Hayato K.G.Hayes A.Hebecker B.Heltsley j.j.Hernandez-Rey K.Hikasa j.Hisano A.Hcker j.Holder A.Holtkamp j.Huston T.Hyodo K.Irwin j.D.jackson K.F.johnson M.Kado M.Karliner U.F.Katz S.R.Klein E.Klempt R.V.Kowalewski F.Krauss M.Kreps B.Krusche Yu.V.Kuyanov Y.Kwon O.Lahav j.Laiho P.Langacker A.Liddle Z.Ligeti C.-j.Lin C.Lippmann T.M.Liss L.Littenberg K.S.Lugovsky S.B.Lugovsky A.Lusiani Y.Makida F.Maltoni T.Mannel A.V.Manohar W.j.Marciano A.D.Martin A.Masoni j.Matthews U.-G.Meiβner D.Milstead R.E.Mitchell P.Molaro K.Mnig F.Moortgat M.j.Mortonson H.Murayama K.Nakamura M.Narain P.Nason S.Navas M.Neubert P.Nevski Y.Nir K.A.Olive S.Pagan Griso j.Parsons j.A.Peacock M.Pennington S.T.Petcov V.A.Petrov A.Piepke A.Pomarol A.Quadt S.Raby j.Rademacker G.Raffelt B.N.Ratcliff P.Richardson A.Ringwald S.Roesler S.Rolli A.Romaniouk L.j.Rosenberg j.L.Rosner G.Rybka R.A.Ryutin C.T.Sachrajda Y.Sakai G.P.Salam S.Sarkar F.Sauli O.Schneider K.Scholberg A.j.Schwartz D.Scott V.Sharma S.R.Sharpe T.Shutt M.Silari T.Sjstrand P.Skands T.Skwarnicki j.G.Smith G.F.Smoot S.Spanier H.Spieler C.Spiering A.Stahl S.L.Stone Y.Sumino T.Sumiyoshi M.j.Syphers F.Takahashi M.Tanabashi K.Terashi j.Terning R.S.Thorne L.Tiator M.Titov N.P.Tkachenko N.A.Trnqvist D.Tovey G.Valencia R.Van de Water N.Varelas G Particle Data Group Universita di Bologna and INFN Dip.Scienze per la Qualita della Vita University of Maryland Department of Physics College Park Universit degli Studi di Roma "Tor Vergata" Albert Einstein Center for Fundamental Physics Universitt Bern Stefan Meyer Institute for Subatomic Physics Austrian Academy of Sciences Lab.Nazionali di Frascati dell'INFN Pacific Northwest National Laboratory Department of Physics and Astronomy University of Oklahoma University of Louisville Physics Division Lawrence Berkeley National Laboratory CERN European Organization for Nuclear Research Department of Physics The Ohio State University COMPAS Group Institute for High Energy Physics Max-Planck-Institute of Physics Department of Physics University of Washington Ludwig-Maximilians-Universitt Fakultt fr Physik Enrico Fermi Institute and Department of Physics University of Chicago Department of Physics Columbia University High Energy Physics Group Blackett Laboratory Imperial College jefferson Lab Department of Physics University of Virginia Fermi National Accelerator Laboratory Kavli Institute for Cosmological Physics University of Chicago Department of Physics and Astronomy University of Sussex Department of Physics Northern Illinois University Department of Physics and Astronomy University of California Michigan State University Dept.of Physics and Astronomy Department of Physics Royal Holloway University of London INFN-Sezione di Napoli Complesso Universitario Monte Sant'Angelo Institut des Hautes Etudes Scientifiques International Center for Advanced Studies(ICAS) UNSAM Department of Physics and Astronomy Northwestern University Department of Physics University of Colorado at Boulder Nikhef P.O.Box 41882 1009 DB Amsterdam and University of Amsterdam Institute for Particle Physics ETH Zurich University of Liverpool Department of Physics Oliver Lodge Lab Physikalisches Institut Universitt Bonn Helsinki Institute of Physics University of Helsinki Department of Physics Budker Institute of Nuclear Physics SB RAS Novosib

The Review summarizes much of particle physics and *** data from previous editions,plus 3,062 new measurements from 721 papers,we list,evaluate,and average measured properties of gauge bosons and the recently discovered Higgs boson,leptons,quarks,mesons,and *** summarize searches for hypothetical particles such as supersymmetric particles,heavy bosons,axions,dark photons,*** the particle properties and search limits are listed in Summary *** also give numerous tables,figures,formulae,and reviews of topics such as Higgs Boson Physics,Supersymmetry,Grand Unified Theories,Neutrino Mixing,Dark Energy,Dark Matter,Cosmology,Particle Detectors,Colliders,Probability and *** the 117 reviews are many that are new or heavily revised,including new reviews on Pentaquarks and Inflation.

关键词： Standard Model and Related Topics

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Index

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Chinese Physics C 2016年第10期 901-914页

关键词： Index USA

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Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira M.Holmström Henri j.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic

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Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging

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Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.Gunn Laura Bennet Hamid Abbasi Mātai Medical Research Institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical Imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering Institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

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Suppression of bile acid synthesis by thyroid hormone in primary human hepatocytes

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World journal of Gastroenterology 2006年第29期12卷 4640-4645页

作者： Ewa Cristine Siljevik ellis Department of Medicine Division of Gastroenterology and Hepatology and the Department of Laboratory MedicineDivision of Clinical ChemistryKarolinska University Hospital at HuddingeKarolinska InstituteStockholmSweden

AIM： It is known that thyroid hormones alter the bile acid metabolism in humans, however the effect on individual enzymes has been difficult to elucidate. This is mainly due to the lack of human liver cell lines producing bile acids. We used cultures of primary human hepatocytes to study the effects of triiodothyronine （T3） on bile acid synthesis.METHODS： Primary hepatocytes were isolated from liver tissue obtained from three different patients undergoing liver resection due to underlying malignancy. The hepatocytes were cultured under serum-free conditions and treated from d 1 to d 5 with culture containing 0.1 - 1000 nmol/L of T3. Bile acid formation and mRNA levels of key enzymes were analysed. RESULTS： The lowest concentration of T3 decreased cholic acid （CA） formation to 43%-53% of controls and chenodeoxycholic acid （CDCA） to 52%-75% of controls on d 5. The highest dose further decreased CA formation to 16%-48% of controls while CDCA formation remained at 50%-117% of controls. Expression of mRNA levels of cholesterol 7α-hydroxylase （CYP7A1） and sterol 12α-hydroxylase （CYPSB1） dose-dependently decreased. Sterol 27-hydroxylase （CYP27A1） levels also decreased, but not to the same extent. CONCLUSION： T3 dose-dependently decreased total bile acid formation in parallel with decreased expression of CYP7A1 and CYP8B1. CA formation is inhibited to a higher degree than CDCA, resulting in a marked decrease in the CA/CDCA ratio.

关键词： Hepatocytes Human Bile acids CYP7A1 CYPSB1 CYP27A1

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Modulation of ice ages via precession and dust-albedo feedbacks

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Geoscience Frontiers 2016年第6期7卷 891-909页

作者： Ralph ellis Michael Palmer 105-6817 Route Pommier St Martin Bellevue 74370France University of Waterloo Department of ChemistryWaterlooOntarioCanada

We present here a simple and novel proposal for the modulation and rhythm of ice-ages and interglacials during the late Pleistocene. While the standard Milankovitch-precession theory fails to explain the long intervals between interglacials, these can be accounted for by a novel forcing and feedback system involving CO2, dust and albedo. During the glacial period, the high albedo of the northern ice sheets drives down global temperatures and CO2 concentrations, despite subsequent precessional forcing maxima. Over the following millennia more CO2 is sequestered in the oceans and atmospheric concentrations eventually reach a critical minima of about 200 ppm, which combined with arid conditions, causes a die-back of temperate and boreal forests and grasslands, especially at high altitude. The ensuing soil erosion generates dust storms, resulting in increased dust deposition and lower albedo on the northern ice sheets. As northern hemisphere insolation increases during the next Milankovitch cycle, the dust-laden ice-sheets absorb considerably more insolation and undergo rapid melting, which forces the climate into an interglacial period. The proposed mechanism is simple, robust, and comprehensive in its scope, and its key elements are well supported by empirical evidence.

关键词： Paleoclimatology Ice-age Precession CO2 Albedo Dust

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Small extrachromosomal circular DNA in amyotrophic lateral sclerosis matter

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Neural Regeneration Research 2025年第5期20卷 1411-1413页

作者： Marcos j.Arauzo-Bravo Daniela Gerovska Matthias Schwab Alexandra Kretz Computational Biology and Systems Biomedicine Biodonostia Health Research InstituteSan SebastianSpain Basque Foundation for Science IKERBASQUEBilbaoSpainMax Planck Institute for Molecular BiomedicineComputational Biology and Bioinformatics GroupMünsterNorth Rhine-WestphaliaGermany Department of Cell Biology and Histology Faculty of Medicine and NursingUniversity of Basque Country(UPV/EHU)LeioaSpain Department of Neurology Jena University HospitalJenaThuringiaGermany

Comprehensive studies identify motor neuron spectrum disorders including amyotrophic lateral sclerosis(ALS)as globally rising fatal disorders with the highest prevalence in aging populations,influenced by ethnicity and ancestry(GBD 2016 Motor Neuron Disease Colla borators,2018).While~10% of diagnoses involve a family history(fALS),most cases are considered sporadic(sALS).However,population-based studies suggest that even cases without a common index mutation impart heritability(Ryan et al.,2019),indicating a crucial role of rare and as yet unknown genetic denominators.

关键词： amyotrophic sclerosis

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Scalable gas-phase processes to create nanostructured particles

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Particuology 2010年第6期8卷 572-577页

作者： j.Ruud van Ommen Caner U.Yurteri Naoko ellis Erik M.Kelder Delft University of Technology Department of Chemical EngineeringJulianalaan 1362628 BL DelftThe Netherlands University of British Columbia Department of Chemical and Biological Engineering2360 East MallVancouverB.C.Canada V6T 1Z3

The properties of nanoparticles are often different from those of larger grains of the same solid material because of their very large specific surface area. This enables many novel applications, but properties such as agglomeration can also hinder their potential use. By creating nanostructured particles one can take optimum benefit from the desired properties while minimizing the adverse effects. We aim at developing high-precision routes for scalable production of nanostructured particles. Two gas-phase synthesis routes are explored. The first one - covering nanoparticles with a continuous layer - is carried out using atomic layer deposition in a fluidized bed. Through fluidization, the full surface area of the nanoparticles becomes available. With this process, particles can be coated with an ultra-thin film of constant and well-tunable thickness. For the second route - attaching nanoparticles to larger particles - a novel approach using electrostatic forces is demonstrated. The micron-sized particles are charged with one polarity using tribocharging. Using electrospraying, a spray of charged nanoparticles with opposite polarity is generated. Their charge prevents agglomeration, while it enhances efficient deposition at the surface of the host particle. While the proposed processes offer good potential for scale-up, further work is needed to realize large-scale processes.

关键词： Nanoparticles Nanocomposite materials Coating Films Particle coating Atomic layer deposition Core-shell particles Electrospraying Electrohydrodynamic atomization Electrostatic forces Fluidization

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Maximizing biomass utilization: An integrated strategy for coproducing multiple chemicals

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journal of Energy Chemistry 2025年第1期100卷 180-191页

作者： Byeongchan Ahn Sua jo jonggeol Na j.jay Liu Young-ju Kim Wangyun Won Department of Chemical and Biological Engineering Korea University Department of Chemical Engineering (Integrated process) Kyung Hee University Department of Chemical Engineering and Materials Science Ewha Womans University Department of Chemical Engineering Pukyong National University Resources Engineering Plant Research Department Korea Institute of Geoscience and Mineral Resources

Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol（1,6-HDO） with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments（LCAs）.Strategy A was found to be the most favorable both economically（USRDSCHARDOLLAR3,402/ton） and environmentally（-26.9 kg CO2eq.）. This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.

关键词： Carbon capture and utilization

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Combinatorial therapies for spinal cord injury repair

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Neural Regeneration Research 2025年第5期20卷 1293-1308页

作者： Carla S.Sousa Andreia Monteiro António j.Salgado Nuno A.Silva Life and Health Sciences Research Institute(ICVS) School of MedicineUniversity of MinhoCampus de Gualtar-gualtarBragaPortugal ICVS/3B’s Associate Lab PT Government Associated LabCampus de Gualtar-gualtarBragaPortugal

Spinal cord injuries have profound detrimental effects on individuals, regardless of whether they are caused by trauma or non-traumatic events. The compromised regeneration of the spinal cord is primarily attributed to damaged neurons, inhibitory molecules, dysfunctional immune response, and glial scarring. Unfortunately, currently, there are no effective treatments available that can fully repair the spinal cord and improve functional outcomes. Nevertheless, numerous pre-clinical approaches have been studied for spinal cord injury recovery, including using biomaterials, cells, drugs, or technological-based strategies. Combinatorial treatments, which target various aspects of spinal cord injury pathophysiology, have been extensively tested in the last decade. These approaches aim to synergistically enhance repair processes by addressing various obstacles faced during spinal cord regeneration. Thus, this review intends to provide scientists and clinicians with an overview of pre-clinical combinatorial approaches that have been developed toward the solution of spinal cord regeneration as well as update the current knowledge about spinal cord injury pathophysiology with an emphasis on the current clinical management.

关键词： electric stimulation neural tissue regeneration neuroprotection polytherapy spinal cord injury

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