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Risk analysis and maintenance decision making of natural gas pipelines with external corrosion based on Bayesian network

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Petroleum Science 2022年第3期19卷 1250-1261页

作者： Yun-Tao li xiao-Ning he jian Shuai College of Safety and Ocean Engineering China University of PetroleumBeijingChina

Buried natural gas pipelines are vulnerable to external corrosion because they are encased in a soil environment for a long *** the causes of external corrosion and taking specific maintenance measures is *** this work,a risk analysis and maintenance decision-making model for natural gas pipelines with external corrosion is proposed based on a Bayesian network.A fault tree model is first employed to identify the causes of external *** Bayesian network for risk analysis is determined *** maintenance strategies are then inserted into the Bayesian network to show a reduction of the *** costs of maintenance strategies and the reduced risk after maintenance are combined in an optimization function to build a decision-making *** of the limitations of historical data,some of the parameters in the Bayesian network are obtained from a probabilistic estimation model,which combines expert experience and fuzzy set ***,a case study is carried out to verify the feasibility of the maintenance decision *** indicates that the method proposed in this work can be used to provide effective maintenance schemes for different pipeline external corrosion scenarios and to reduce the possible losses caused by external corrosion.

关键词： Natural gas pipelines External corrosion Risk analysis Maintenance decision making Bayesian network

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第1期68卷 288-296页

作者： Shuai liu Wen-Qiang Xu Ying-Tong Di Man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan jun-Bo Yang Zhi-li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu xiao-jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

关键词： metabolon Diels-Alder reaction semipinacol rearrangement biosynthesis notoamides spiro polycyclic alkaloids

ANALYTICAL SOLUTION OF LONGITUDINAL DISPERSION IN DOUBLE-LAYER STRATIFIED TURBULENT FLOW

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journal of Hydrodynamics 1991年第3期3卷 74-78页

作者： xiao-ping, Xu li, he Wuhan Univ of Hydraulic and Electric Engineering Wuhan China

In double-layer stratified turbulent flow, the deviation function of the concentration from the cross-section mean and the dispersion coefficients are studied. The one-dimensional simplified dispersion equation is extended to double-layer turbulent flow. The velocity distribution in the upper flow region is logarithmic, and in the lower region is of the power-law. The paper gives particular forms of the concentration deviation functions and accurate formulae of longitudinal dispersion coefficients.

关键词： Computers Applications Diffusion Fluid Mechanics Hydrodynamics Mathematical Models

You Are How You Behave-Spatiotemporal Representation Learning for College Student Academic Achievement

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journal of Computer Science & Technology 2020年第2期35卷 353-367页

作者： xiao-lin li li Ma Xiang-Dong he Hui Xiong School of Business Nanjing UniversityNanjing 210093China Information Technology Services Center Nanjing UniversityNanjing 210093China School of Business Rutgers UniversityNewarkNJ 07102U.S.A.

Scholarships are a reflection of academic achievement for college *** traditional scholarship assignment is strictly based on final grades and cannot recognize students whose performance trend improves or declines during the *** paper develops the Trajectory Mining on Clustering for Scholarship Assignment and Academic Warning(TMS)approach to identify the factors that affect the academic achievement of college students and to provide decision support to help low-performing students attain better ***,we first conduct feature engineering to generate a set of features to characterize the lifestyles patterns,learning patterns,and Internet usage patterns of *** then apply the objective and subjective combined weighted k-means(Wosk-means)algorithm to perform clustering analysis to identify the characteristics of different student *** the difficulty in obtaining the real global positioning system(GPS)records of students,we apply manually generated spatiotemporal trajectories data to quantify the direction of trajectory deviation with the assistance of the PrefixSpan algorithm to identify low-performing *** experimental results show that the silhouette coefficient and Calinski-Harabasz index of the Wosk-means algorithm are both approximately 1.5 times to that of the best baseline algorithm,and the sum of the squared error of the Wosk-means algorithm is only the half of the best baseline algorithm.

关键词： academic achievement spatiotemporal trajectory feature engineering student segmentation

Review and prospect of NiCo_(2)O_(4)-based composite materials for supercapacitor electrodes

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journal of Energy Chemistry 2019年第4期28卷 54-78页

作者： Yanmei li xiao Han Tingfeng Yi Yanbing he Xifei li School of Chemistry and Chemical Engineering Anhui University of Technology School of Resources and Materials Northeastern University at Qinhuangdao Engineering Laboratory for the Next Generation Power and Energy Storage Batteries Graduate School at Shenzhen Tsinghua University Institute of Advanced Electrochemical Energy Xi'an University of Technology

Supercapacitors known as typical electrochemical capacitors have been considered as one of the most promising candidates of energy storage systems owing to their advantages such as high-power density,long life span and lower production *** electrode materials play a crucial role on properties of ***,many researches have been focused on the development of novel electrode materials for high-performance ***_2O_4as supercapacitor electrode material has drawn more and more attentions in recent years due to its outstanding advantages,such as high theoretical capacity,low cost,natural abundance and easy of ***,the NiCo_2O_4always suffer from severe capacity deterioration because of the low electrical conductivity and small surface ***,it is necessary to systematically and comprehensively summarize the progress in understanding and modifying NiCo_2O_4-based materials from various *** this review,the structure and synthesis method of NiCo_2O_4-based materials are discussed in *** then,the major goal of this review is to highlight new progress in using proposed strategies to improve the cycling stability and rate capacity of NiCo_2O_4-based materials,including synthesis,control of special morphologies and design of composite ***,an insight into the future research and development of Ni Co_2O_4-based materials for supercapacitors is prospected.

关键词： NiCo_(2)O_(4) Electrochemical performance Synthesis Morphology Supercapacitors

CO2-mediated bicarbonate conversion to concentrated formate in a CEM-based electrolyzer

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journal of Energy Chemistry 2025年第1期100卷 605-611页

作者： Haocheng Xiong Donghuan Wu Haonan li Andrew li Qikun Hu Siyao Song Bingjun Xu Qi Lu State Key Laboratory of Chemical Engineering Department of Chemical Engineering Tsinghua University College of Chemistry and Molecular Engineering Peking University Ordos Laboratory

Renewable energy-driven bicarbonate conversion to valuable chemicals presents an attractive strategy for mitigating CO2emissions,as bicarbonate can be efficiently generated from the capture of atmospheric CO2using alkaline solutions with reactive *** this work,we present a CO2-mediated bicarbonate conversion to pure formate using a cation exchange membrane-based electrolyzer with a 25 cm2electrode *** electrolysis achieved selectivities exceeding 75%for formate at a total current of 2.5 A,achieving formate concentrations up to 1.2 M and yields as high as 95%over extended *** techno-economic assessment confirmed the economic viability of the process,highlighting the potential for bicarbonate electrolysis as a sustainable method for producing valuable chemicals.

关键词： Electrocatalysis Techno-economic assessments Electrochemistry Flow electrolyzer

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis

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Neural Regeneration Research 2025年第2期20卷 354-365页

作者： li Xu Huiming Xu Changyong Tang Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor *** date,no effective treatment exists as the exact causative mechanism remains ***,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic *** most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets *** experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum *** this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model *** addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

关键词： aquaporin-4 experimental model neuromyelitis optica spectrum disorder pathogenesis

Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss

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Neural Regeneration Research 2025年第10期20卷 3025-3039页

作者： jia Fang Zhuangzhuang li Pengjun Wang xiaoxu Zhang Song Mao Yini li Dongzhen Yu xiaoyan li Yazhi Xing Haibo Shi Shankai Yin Department of Otolaryngology head and Neck Surgery Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineOtolaryngology Institute of Shanghai Jiao Tong UniversityShanghai Key Laboratory of Sleep Disordered BreathingShanghaiChina Department of Otorhinolaryngology-head and Neck Surgery Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Aminoglycosides are a widely used class of antibacterials renowned for their effectiveness and broad antimicrobial ***,their use leads to irreversible hearing damage by causing apoptosis of hair cells as their direct *** addition,the hearing damage caused by aminoglycosides involves damage of spiral ganglion neurons upon *** investigate the mechanisms underlying spiral ganglion neuron degeneration induced by aminoglycosides,we used a C57BL/6j mouse model treated with *** found that the mice exhibited auditory deficits following the acute loss of outer hair *** ganglion neurons displayed hallmarks of pyroptosis and exhibited progressive degeneration over *** profiling of these neurons showed significant upregulation of genes associated with inflammation and immune response,particularly those related to the NLRP3 *** of the canonical pyroptotic pathway in spiral ganglion neurons was observed,accompanied by infiltration of macrophages and the release of proinflammatory *** intervention targeting NLRP3 using Mcc950 and genetic intervention using NLRP3 knockout ameliorated spiral ganglion neuron degeneration in the injury *** findings suggest that NLRP3 inflammasome-mediated pyroptosis plays a role in aminoglycoside-induced spiral ganglion neuron *** of this pathway may offer a potential therapeutic strategy for treating sensorineural hearing loss by reducing spiral ganglion neuron degeneration.

关键词： degeneration hearing loss macrophages Mcc950 neuroinflammation NLRP3 inflammasome ototoxicity pyroptosis sensorineural hearing loss spiral ganglion neuron

Regulating crystallization and retarding oxidation in Sn-Pb perovskite via 1D cation engineering for high performance all-perovskite tandem solar cells

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journal of Energy Chemistry 2025年第1期100卷 646-652页

作者： Ranran liu Xin Zheng Zaiwei Wang Miaomiao Zeng Chunxiang Lan Shaomin Yang Shangzhi li Awen Wang Min li jing Guo Xuefei Weng Yaoguang Rong Xiong li Michael Gr?tzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced Technology Chinese Academy of Sciences School of Physics and Optoelectronic Engineering Hainan University Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO) Chinese Academy of Sciences School of Chemistry Chemical Engineering and Life Sciences State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology

All-perovskite tandem solar cells have the potential to surpass the theoretical efficiency limit of single junction solar cells by reducing thermalization ***,the challenges encompass the oxidation of Sn2+to Sn4+and uncontrolled crystallization kinetics in Sn-Pb perovskites,leading to nonradiative recombination and compositional heterogeneity to decrease photovoltaic efficiency and operational ***,we introduced an ionic liquid additive,1-ethyl-3-methylimidazolium iodide （EMIMI） into Sn-Pb perovskite precursor to form low-dimensional Sn-rich/pure-Sn perovskites at grain boundaries,which mitigates oxidation of Sn2+to Sn4+and regulates the film-forming dynamics of Sn/Pb-based perovskite *** optimized single-junction Sn-Pb perovskite devices incorporating EMIMI achieved a high efficiency of 22.87%.Furthermore,combined with wide-bandgap perovskite sub-cells in tandem device,we demonstrate 2-terminal all-perovskite tandem solar cells with a power conversion efficiency of 28.34%,achieving improved operational stability.

关键词： All-perovskite tandem solar cells Sn-Pb perovskite 1D Regulated crystallization Antioxidation