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肝细胞癌长入胆管的瘤灶在化学栓塞术后的脱落

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国际医学放射学杂志 2016年第4期 457-458页

作者： G.M.Kim H.C.Kim S.H.Myungsu L.H.j.jae j.w.chung 卢宝兰 Department of Radiology Research Institute Radiological Science Severance Hospital Yonsei University College of Medicine

摘要目的分析探讨肝细胞癌长入胆管的瘤灶在化学栓塞术后脱落的影像表现及临床病程。方法回顾性分析12例经化学栓塞术后胆管瘤灶脱落的肝细胞癌病人的流行病学特点、临床表现和治疗方式。在CT上观察记录胆管瘤灶的大小(累及胆管的长度)... 详细信息

摘要目的分析探讨肝细胞癌长入胆管的瘤灶在化学栓塞术后脱落的影像表现及临床病程。方法回顾性分析12例经化学栓塞术后胆管瘤灶脱落的肝细胞癌病人的流行病学特点、临床表现和治疗方式。在CT上观察记录胆管瘤灶的大小(累及胆管的长度)、密度及随访过程的变化。结果胆管

关键词：化学栓塞术长入肝细胞癌胆管瘤

氰基丙烯酸正丁酯与聚乙烯醇颗粒栓塞支气管动脉控制咯血的比较

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国际医学放射学杂志 2014年第1期 72-73页

作者： S.woo C.j.Yoon j.w.chung S.G.Kang H.j.jae H.C.Kim 袁涛 Department of radiology Seoul national university Bundang hospital166 Gumi-roBundang-guSeongnam-siGyeonggi-do 463-707Korea

目的回顾性比较栓塞剂聚乙烯醇(PVA)颗粒与氰基丙烯酸正丁酯(NBCA)行支气管动脉栓塞(BAE)控制咯血的安全性与效能。方法本回顾性研究获得医院伦理委员

关键词：氰基丙烯酸正丁酯颗粒 PVA NBCA 栓塞病理

门静脉高压与肝细胞癌肝动脉化学栓塞术后预后不良相关

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国际医学放射学杂志 2018年第4期 492-492页

作者： j.w.Choi j.w.chung D.H.Lee H.C.Kim S.Hur M.Lee 陈圣妮 Section of Interventional Radiology Department of RadiologySeoul National University College of MedicineSeoul National University Hospital

目的探讨临床相关性门静脉高压症(CRPH)是否影响预后,是否可作为肝细胞癌肝动脉化学栓塞术(TACE)后的预后指标。方法共纳入147例病人,接受常规TACE作为单个HCC病灶的一线治疗。CRPH评分为0、1或2。应用Cox比例风险回归模型分析CRPH和其... 详细信息

目的探讨临床相关性门静脉高压症(CRPH)是否影响预后,是否可作为肝细胞癌肝动脉化学栓塞术(TACE)后的预后指标。方法共纳入147例病人,接受常规TACE作为单个HCC病灶的一线治疗。CRPH评分为0、1或2。应用Cox比例风险回归模型分析CRPH和其他因素对局部肿瘤进展(LTP)以及总生存期(OS)的影响。结果对CRPH分级较高[1级,P=0.005,危险比(HR)=3.282;2级,P<0.001,HR=7.144]和选择性导管插入较少(P=0.009,HR=1.951)与早期LTP显著相关。至于OS,年龄(P<0.001,HR=1.050)、CRPH 2级(P=0.024,HR=2.058)、较大肿瘤(P<0.001,HR=1.454)与早期死亡显著相关。结论门静脉高压症与TACE术后预后不良显著相关,无创性CRPH分级也许可作为TACE术后有效的预后指标。

关键词：肝细胞癌门静脉高压症预后不良

肥厚性心肌病病人右心室插入点MRI延迟强化的范围:与心脏舒张功能障碍相关

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国际医学放射学杂志 2015年第3期 305-305页

作者： Y.Zhu E.A.Park w.Lee H.K.Kim A.Chu j.w.chung 钱力可 Department of Radiology Seoul National University Hospital28 Yongon-Dong Chongno-GuSeoul 110-744 Korea

目的阐述肥厚性心肌病(HCM)病人右心室插入点(RVIP)MRI延迟强化(LGE)范围与左心室功能参数的关系。方法 61例HCM病人于1周内分别接受超声心动图及

关键词：肥厚性心肌病插入点延迟强化右心室心尖肥厚 MRI 病人

C臂CT肝动脉成像中肝脏镰状韧带的动脉:肝镰状动脉和萨佩氏上动脉

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国际医学放射学杂志 2017年第3期 363-363页

作者： S.Hur j.w.chung C.G.Zhou j.H.Lee S.B.Cho M.Kim 郭小琴 Department of Radiology Seoul National University Hospital

摘要目的应用C臂CT肝动脉成像(C臂CTHA)研究肝镰状动脉(HFA)和萨佩氏上动脉(SSA)的出现率、解剖和分布。方法在此回顾性研究中共纳入220例病人,均自2011年1月—2012年12月因肝细胞肝癌初次通过C臂CTHA接受动脉介入治疗。HFA和SSA的出现... 详细信息

摘要目的应用C臂CT肝动脉成像(C臂CTHA)研究肝镰状动脉(HFA)和萨佩氏上动脉(SSA)的出现率、解剖和分布。方法在此回顾性研究中共纳入220例病人,均自2011年1月—2012年12月因肝细胞肝癌初次通过C臂CTHA接受动脉介入治疗。HFA和SSA的出现率和起源通过C臂CTHA的横断面影像进行评估。HFA的5分量表和SSA的4分量表用来定义影像上两动脉的显示情况。结果总体HFA和SSA的出现率分别为95%(209例)和22%(49例),而在影像上两者明显显示的比例分别为62%(137例)和10%

关键词：动脉 CTHA 出现率 CT HFA 镰状韧带

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选择性化疗栓塞治疗尾状叶肝细胞癌

国际医学放射学杂志 2010年第6期 580-580页

作者： H.C.Kim j.w.chung H.j.jae j.H.Yoon j.H.Lee Y.j.Kim 蔡华琦 Clinical Research Institute Seoul National University Hospital#28 Yongon-dongChongno-guSeoul 110-744Korea

目的分析早期单发性尾状叶肝细胞癌化疗栓塞的临床治疗效果。材料与方法本次回顾性研究获得伦理审查委员会批准,免除病人知情同意。收集1998年7月-2009

关键词：尾状叶临床治疗效果单发性化疗栓塞肝细胞癌

隐匿性胃肠道出血:多层螺旋CT小肠成像的诊断能力

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国际医学放射学杂志 2011年第4期 384-384页

作者： S.S.Lee T.S.Oh H.j.Kim j.w.chung S.H.Park A.Y.Kim 吴瑕 Department of Radiology and Research Institute of Radiology and Department of Gastroenterology University of Ulsan College of MedicineAsan Medical Center

目的评估CT小肠成像对明确隐匿性胃肠道出血原因的诊断能力,确定具有较高CT小肠成像诊断率相关的临床特征。材料与方法本研究经伦理委员会同意,不需知情同意书。由2名放射科医师分别对2005年8月—2007年7

关键词：胃肠道出血隐匿性小肠诊断能力 CT

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn j.w.So Konstantin Feinberg Marina Manoraj jenny Cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

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Dual‑Donor‑Induced Crystallinity Modulation Enables 19.23% Efficiency Organic Solar Cells

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Nano-Micro Letters 2025年第3期17卷 376-388页

作者： Anhai Liang Yuqing Sun Sein chung jiyeong Shin Kangbo Sun Chaofeng Zhu jingjing Zhao Zhenmin Zhao Yufei Zhong Guangye Zhang Kilwon Cho Zhipeng Kan Center On Nanoenergy Research Institute of Science and Technology for Carbon Peak&NeutralitySchool of Physical Science&TechnologyGuangxi UniversityNanning 530004People’s Republic of China Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673South Korea College of New Materials and New Energies Shenzhen Technology UniversityShenzhen 518118People’s Republic of China Zhejiang Engineering Research Center for Fabrication and Application of Advanced Photovoltaic Materials School of Materials Science and EngineeringNingboTech UniversityNingbo 315100People’s Republic of China State Key Laboratory of Featured Metal Materials and Life-Cycle Safety for Composite Structures Nanning 530004People’s Republic of China

Trap-assisted charge recombination is one of the primary limitationsof restricting the performance of organic solar cells. However, effectivelyreducing the presence of traps in the photoactive layer remains ***, wide bandgap polymer donor PTzBI-dF is demonstrated as an effectivemodulator for enhancing the crystallinity of the bulk heterojunction active layerscomposed of D18 derivatives blended with Y6, leading to dense and orderedmolecular packings, and thus, improves photoluminescence quenching *** a result, the photovoltaic devices exhibit reduced trap-assisted charge recombinationlosses, achieving an optimized power conversion efficiency of over 19%.Besides the efficiency enhancement, the devices comprised of PTzBI-dF as athird component simultaneously attain decreased current leakage, improved chargecarrier mobilities, and suppressed bimolecular charge recombination, leading toreduced energy losses. The advanced crystalline structures induced by PTzBI-dFand its characteristics, such as well-aligned energy level, and complementaryabsorption spectra, are ascribed to the promising performance *** findings suggest that donor phase engineering is a feasible approach to tuning the molecular packings in the active layer, providingguidelines for designing effective morphology modulators for high-performance organic solar cells.

关键词： Trap-assisted charge recombination Photoluminescence Miscibility Current leakage Power conversion efficiency

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