检索结果-南通市图书馆

Risk of Cardiovascular Events in Patients with Primary Biliary Cholangitis-Systematic Review

journal of Clinical and Translational Hepatology 2018年第2期6卷 119-126页

作者： Duminda Suraweera Christina Fanous Melissa jimenez Myron j.tong Sammy Saab Department of Medicine Olive-View Medical CenterSylmarCAUSA Department of Surgery at the University of California at Los Angeles Los AngelesCAUSA Huntington Research Institute PasadenaCAUSA Department of Medicine at the University of California at Los Angeles Los AngelesCAUSA

Background and Aims:Hypercholesterolemia is a common finding in patients with primary biliary cholangitis(PBC)and is a well-defined risk factor for cardiovascular ***,studies have been mixed on whether PBC patients do,in fact,have higher cardiovascular *** aim of this study is to review the current literature and provide an evidence-based assessment of cardiovascular risk in PBC ***:We performed a systematic literature search on PubMed re-garding patients with PBC and cardiovascular events from the database inception to july 1,2017.A total of 33 articles ful-filling our inclusion criteria were ***:The majority of the studies evaluated yielded no statistically significant dif-ference in cardiovascular disease in the PBC population com-pared to the general ***,some reports found a statistically significantly increase in coronary artery *** studies have looked at the specific lipid profile of pa-tients with PBC with *** these lipid ab-normalities differ by stage of disease,there is evidence to suggest that the specific lipid profile in PBC may have lower atherogenicity than in patients with hypercholesterolemia without *** looking at patients with PBC with other risk factors for cardiovascular disease,such as hypertension and metabolic syndrome,have consistently found a higher risk for cardiovascular disease in these *** treat-ment is effective in reducing lipid levels and possibly improv-ing endothelial inflammation in patients with PBC with ***:There is not enough evidence to suggest an increased risk of cardiovascular dis-ease in patients with PBC with hypercholesterolemia,except for those individuals with concomitant features of metabolic *** patients with PBC with no additional cardiovas-cular risk factors,individual risk/benefit discussion on lipid-lowering treatment should be considered.

关键词： Primary biliary cholangitis(PBC) Cardiovascular risk Hypercholesterolemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatocellular Carcinoma

Hepatocellular Carcinoma

引用

第6届全国疑难及重症肝病大会

作者： Myron j.tong Liver Center Huntington Medical Research InstitutesUnited States

Hepatocellular carcinoma(HCC)is a common malignancy *** is the 5th leading cause of cancer in men and the 8th leading cause in females. Globally,HCC is the 3rd leading cause of cancer related death in men and 6th in *** and Africa are considered hi!gh prevalence areas while the United States has intermediate *** factors for HCC have geographical

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Unique microstructure and thermal insulation property of a novel waste-utilized foam ceramic

引用

journal of Materials Science & Technology 2020年第13期47卷 175-179页

作者： F.H.Kuang S.M.Wang C.Gao H.B.Zhang R.K.Ren j.L.Ren j.tong Y.M.Liu Department of Materials Science and Engineering University of Science&Technology BeijingBeijing 100083China China Building Materials Academy Beijing 100024China China Institute for Radiation Protection Taiyuan 030006China

A characteristic CaO-Al2O3-SiO2 based foam ceramic was prepared by melt-foaming with solid wastes as main raw *** similarity to sandwich hole wall microstructure of this novel thermal insulating material was presented and the relationships between this unique microstructure and porosity,density,thermal conductivity and strength were *** the measured and theoretical values with that of the traditional foam ceramic,it can be found that,for the matching of fine skeleton with hole wall,this original sandwich structure can reduce thermal conductivity and increase flexural strength effectively.

关键词： Foam ceramic Density Porosity Strength Thermal conductivity Sandwich structure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

多晶铂电极表面硫吸附物种的原位表面增强拉曼光谱研究(英文)

引用

电化学 2010年第3期16卷 255-262页

作者： In-Su Park YuYe j.tong 美国乔治敦大学化学系

本工作首次报道了在酸性或碱性电解质中高粗糙度多晶铂电极表面硫物种的吸附、电氧化过程的原位表面增强拉曼光谱研究.分别在两种情况下采集了粗糙铂电极的表面增强拉曼光谱:(a)循环伏安处理后控制一定电位(0.2V)下;(b)逐步控制不同电位... 详细信息

本工作首次报道了在酸性或碱性电解质中高粗糙度多晶铂电极表面硫物种的吸附、电氧化过程的原位表面增强拉曼光谱研究.分别在两种情况下采集了粗糙铂电极的表面增强拉曼光谱:(a)循环伏安处理后控制一定电位(0.2V)下;(b)逐步控制不同电位.酸性电解质条件下,两种情况均观察到位于300cm-1的Pt—S振动.Pt—S键较强,阻止了氢在铂电极表面的吸附,需多次循环伏安处理才能完全将表面吸附的硫去除.同时还观察到位于470cm-1处的少量多聚S物种(S8或者其他类型).这些多聚S物种仅仅微弱地键合在铂电极的表面,可以容易地除去.在碱性电解质中,同样也在(a)和(b)情况下观察到位于310cm-1的Pt—S振动吸收.本工作了获得了有关硫在粗糙多晶铂电极表面吸附和电氧化重要信息,证明了原位表面增强拉曼光谱在研究铂表面的适用性.

关键词：铂硫拉曼光谱

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Determination of the vapor pressure and prediction of the polarity for ionic liquid 1-alkyl-3-methylimidazolium propionate [Cnmim][Pro](n = 4, 5, 6)

Determination of the vapor pressure and prediction of the po...

引用

第十七届全国化学热力学和热分析学术会议

作者： R.j.Liu H.X.Yang C.Li j.tong j.Z.Yang Liaoning University

The ionic liquids(ILs) [Cnmim][Pro](n = 4, 5, 6)(1-alkyl-3-methylimidazolium propionate) were prepared by the neutralization method and characterized by 1H-NMR spectroscopy and differential scanning calorimetry(DSC). Using isothermogravimetrical analysis, the vapor pressures in the temperature range of 423.1563.15 K and the enthalpy of vaporization, △g lHo m(Tav), at the average temperature, Tav, for these ILs were determined [1-2]. The difference of heat capacities between the vapor phase and the liquid phase, △g lCp o m, for [Cnmim][Pro](n = 4, 5, 6) were calculated based on the statistical thermodynamics using Verevkin’s method. Therefore, in terms of △g lCp o m, the value of △g lHo m(Tav) can be transformed into △g lHo m(298). Based on Clausius-Clapeyron equation, the hypothetical temperature of normal boiling point(NBP), Tb for [Cnmim][Pro](n = 4, 5, 6) were estimated. In terms of Tb, the values of entropy and the Gibbs free energy of vaporization for these ILs were predicted at different temperatures. Based on Hildebrand’s theory a new method to predict the polarity of the ILs was put forward. The order of the predicted polarity for the ILs is in good agreement with the experiment value.

关键词： Ionic liquid Isothermogravimetrical analysis Vapor pressure Polarity

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Greatly enhanced corrosion/wear resistances of epoxy coating for Mg alloy through a synergistic effect between functionalized graphene and insulated blocking layer

引用

journal of Magnesium and Alloys 2024年第1期12卷 332-344页

作者： Z.Y.Xue X.j.Li j.H.Chu M.M.Li D.N.Zou L.B.tong School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

The poor corrosion and wear resistances of Mg alloys seriously limit their potential applications in various *** conventional epoxy coating easily forms many intrinsic defects during the solidification process,which cannot provide sufficient *** the current study,we design a double-layer epoxy composite coating on Mg alloy with enhanced anti-corrosion/wear properties,via the spin-assisted assembly *** outer layer is functionalized graphene(FG)in waterborne epoxy resin(WEP)and the inner layer is Ce-based conversion(Ce)*** FG sheets can be homogeneously dispersed within the epoxy matrix to fill the intrinsic defects and improve the barrier *** Ce film connects the outer layer with the substrate,showing the transition *** corrosion rate of Ce/WEP/FG composite coating is 2131 times lower than that of bare Mg alloy,and the wear rate is decreased by~90%.The improved corrosion resistance is attributed to the labyrinth effect(hindering the penetration of corrosive medium)and the obstruction of galvanic coupling *** synergistic effect derived from the FG sheet and blocking layer exhibits great potential in realizing the improvement of multi-functional integration,which will open up a new avenue for the development of novel composite protection coatings of Mg alloys.

关键词： Mg alloy Functionalized graphene Epoxy coating Corrosion/wear resistance Blocking layer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Management of gestational diabetes mellitus via nutritional interventions:The relevance of gastric emptying

引用

World journal of Diabetes 2024年第7期15卷 1394-1397页

作者： Wei-Kun Huang Ryan j jalleh Christopher K Rayner tong-Zhi Wu Adelaide Medical School and Centre of Research Excellence in Translating Nutritional Science to Good Health The University of AdelaideAdelaide 5000Australia Adelaide Medical School and Centre of Research Excellence in Translating Nutritional Science to Good Health The University of Adelaide and Department of Gastroenterology and HepatologyRoyal Adelaide HospitalAdelaide 5000Australia

Gestational diabetes mellitus(GDM)represents one of the most common medical complications of pregnancy and is important to the well-being of both mothers and offspring in the short and long *** intervention remains the mainstay for the management of *** efficacy of nutritional approaches(*** restriction and small frequent meals)to improving the maternal-neonatal outcomes of GDM was attested to by Chinese population data,discussed in two articles in recent issues of this ***,a specific focus on the relevance of postprandial glycaemic control was *** rather than fasting hyperglycaemia often represents the predominant manifestation of disordered glucose homeostasis in Chinese women with *** is now increasing appreciation that the rate of gastric emptying,which controls the delivery of nutrients for digestion and absorption in the small intestine,is a key determinant of postprandial glycaemia in both health,type 1 and 2 *** remains to be established whether gastric emptying is abnormally rapid in GDM,particularly among Chinese women,thus contributing to a predisposition to postprandial hyperglycaemia,and if so,how this influences the therapeutic response to nutritional *** is essential that we understand the role of gastric emptying in the regulation of postprandial glycaemia during pregnancy and the potential for its modulation by nutritional strategies in order to improve postprandial glycaemic control in GDM.

关键词： Gastric emptying Postprandial glycaemia Diet Nutritional interventions Gestational diabetes mellitus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cobalt-catalyzed reductive alkynylation to construct C(sp)-C(sp^(3))and C(sp)-C(sp^(2))bonds

引用

Chinese Chemical Letters 2024年第7期35卷 253-258页

作者： Lei Wan Yizhou tong Xi Lu Yao Fu Hefei National Research Center for Physical Sciences at the Microscale iChEMCAS Key Laboratory of Urban Pollutant ConversionAnhui Province Key Laboratory of Biomass Clean EnergyUniversity of Science and Technology of ChinaHefei 230026China Key Laboratory of Precision and Intelligent Chemistry School of Chemistry and Materials ScienceUniversity of Science and Technology of ChinaHefei 230026China

Transition-metal-catalyzed cross-electrophile coupling has emerged as a reliable method for constructing carbon–carbon ***,we report a general method,cobalt-catalyzed reductive alkynylation,to construct C(sp)-C(sp^(3))and C(sp)-C(sp^(2))*** presented reaction has a broad substrate scope,enabling the efficient cross-electrophile coupling between alkynyl bromides with alkyl halides and aryl or alkenyl(pseudo)*** presented reaction is conducted under mild conditions,tolerating many functional groups,thus suitable for the modification and synthesis of biologically active molecules.

关键词： Cobalt-catalysis Cross-electrophile coupling Carbon-carbon bond formation Reductive alkynylation Alkyne synthesis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A prognosis model for predicting immunotherapy response of esophageal cancer based on oxidative stress-related signatures

引用

Oncology Research 2024年第1期32卷 199-212页

作者： jING GUO CHANGYONG tong jIANGUANG SHI XINjIAN LI XUEQIN CHEN Department of Thoracic Surgery The First Affiliated Hospital of Ningbo UniversityNingboChina Department of Chinese Traditional Medicine The First Affiliated Hospital of Ningbo UniversityNingboChina

Oxidative stress(OS)is intimately associated with tumorigenesis and has been considered a potential therapeutic ***,the OS-associated therapeutic target for esophageal squamous cell carcinoma(ESCC)remains *** our study,gene expression data of ESCC and clinical information from public databases were *** LASSO-Cox regression analysis,a risk score(RS)signature map of prognosis was constructed and performed external verification with the GSE53625 *** ESTIMATE,xCell,CIBERSORT,TIMER,and ImmuCellAI algorithms were employed to analyze infiltrating immune cells and generate an immune microenvironment(IM).Afterward,functional enrichment analysis clarified the underlying mechanism of the *** was utilized for forecasting the survival rate of individual ESCC *** a result,we successfully constructed an OS-related genes(OSRGs)model and found that the survival rate of high-risk groups was lower than that of low-risk *** AUC of the ROC verified the strong prediction performance of the signal in these two cohorts *** to independent prognostic analysis,the RS was identified as an independent risk factor for *** nomogram and follow-up data revealed that the RS possesses favorable predictive value for the prognosis of ESCC ***-PCR detection demonstrated increased expression of MPC1,COX6C,CYB5R3,CASP7,and CYCS in esophageal cancer *** conclusion,we have constructed an OSRGs model for ESCC to predict patients’prognosis,offering a novel insight into the potential application of the OSRGs model in ESCC.

关键词： Esophageal carcinoma OS Prognosis Risk markers Immune cell infiltration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Limited Knowledge of Acetaminophen in Patients with Liver Disease

引用

journal of Clinical and Translational Hepatology 2016年第4期4卷 281-287页

作者： Sarnrny Saab Peter G.Konyn Matthew R.Viramontes Melissa A.jimenez jonathan F.Grotts Wally Hamidzadah Veronica P.Dang Negin L.Esmailzadeh Gina Choi Francisco A.Durazo Mohamed M.El-Kabany Steven-Huy B.Han Myron j.tong Department of Medicine the University of California at Los Angeles Los Angeles CA USA Department of Surgery the University of California at Los Angeles Los Angeles CA USA Department of Surgery the University of California at Los Angeles Los Angeles CA USA Department of Biostatistics the University of California at Los Angeles Los Angeles CA USA Department of Surgery the University of California at Los Angeles Los Angeles CA USA California and Huntington Medical Research Institutes Pasadena CA USA

Background andAims:Unintentional acetaminophen overdose remains the leading cause of acute liver failure in the United *** with underlying liver disease are at higher risk of poor outcomes from acetaminophen *** knowledge of acetaminophen may be a preventable contributor to elevated rates of overdose and thus acute liver *** purpose of this study is to assess knowledge of acetaminophen dosing and presence of acetaminophen in common combination products in patients with liver ***:We performed a cross-sectional study of patients with liver disease at the Pfleger Liver Institute at the University of California,Los Angeles between june 2015 and August *** completed a demographic questionnaire and an acetaminophen knowledge *** information was obtained from the medical ***:Of 401 patients with liver disease,30 (15.7%) were able to correctly identify that people without liver disease can safely take up to 4 g/day of *** majority of patients (79.9%-86.8%) did not know that Norco(R) (hydrocone/acetaminophen),Vicodin(R) (hydrocone/acetaminophen) and Percocet(R) (oxycodone/acetaminophen) contained *** 45.3% of the patients knew that Tylenol(R) #3 contained ***:We conclude that patients with liver disease have critically low levels of knowledge of acetaminophen,putting them at risk both of acetaminophen overdose,as well as undermedication,and inadequate management of chronic *** recommend an increase in education efforts regarding acetaminophen dosage and its safety in the setting of liver *** education for those at risk of low acetaminophen knowledge is essential to minimizing acetaminophen overdose rates and optimizing pain management.

关键词： Acetaminophen Pain management Cirrhosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：