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测定离子注入单晶损伤与应变的双晶(n^v,-n^v)排列方法

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journal of semiconductors 1990年第1期11卷 14-19页

作者：李润身 H.K.Wagenfeld j.s.williams stephen Milkins Andrew stevenson 中国科学院上海冶金研究所 Royal Melbourune Institute of Technology Australia CsIRO.Division of Material science and Technology Australia

依据双晶摇摆曲线的形成原理,提出了一种高分辨率,高灵敏度的测定离子注入单晶损伤与应变的双晶(n^v,—n^v)排列方法。考虑到掠入射情形的色散效应,对掠射角的选择进行了讨论。对Ga注入si单晶样品的测定证实了(n^v—n^v)排列的优越性,... 详细信息

依据双晶摇摆曲线的形成原理,提出了一种高分辨率,高灵敏度的测定离子注入单晶损伤与应变的双晶(n^v,—n^v)排列方法。考虑到掠入射情形的色散效应,对掠射角的选择进行了讨论。对Ga注入si单晶样品的测定证实了(n^v—n^v)排列的优越性,摇摆曲线上得到了未曾见过的细微振荡。

关键词：离子注入单晶损伤硅双晶排列法

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凝析气田中用核磁共振测井确定渗透率

国外测井技术 1998年第4期13卷 33-40页

作者： j·j·hOWARD j.s.williams 朴庆春荆万学

核磁共振（NMR）技术被用于辅助表征北澳大利亚滨海Bayu-undan油田的含气砂岩储层。基于标准算法的NMR测井渗透率在高孔隙度、低粘土含量的砂岩层段中对岩心渗透率低估达两上数量级之多，

关键词：凝析气田核磁共振测井 NMR技术渗透率

Pyrroloquinoline quinone:a potential neuroprotective compound for neurodegenerative diseases targeting metabolism

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Neural Regeneration Research 2025年第1期20卷 41-53页

作者： Alessio Canovai Pete A.williams Department of Biology University of PisaPisaItaly Department of Clinical Neuroscience Division of Eye and VisionSt.Erik Eye HospitalKarolinska InstitutetStockholmSweden

Pyrroloquinoline quinone is a quinone described as a cofactor for many bacterial dehydrogenases and is reported to exert an effect on metabolism in mammalian cells/*** quinone is present in the diet being available in foodstuffs,conferring the potential of this compound to be supplemented by dietary *** quinone’s nutritional role in mammalian health is supported by the extensive deficits in reproduction,growth,and immunity resulting from the dietary absence of pyrroloquinoline quinone,and as such,pyrroloquinoline quinone has been considered as a“new vitamin.”Although the classification of pyrroloquinoline quinone as a vitamin needs to be properly established,the wide range of benefits for health provided has been reported in many *** this respect,pyrroloquinoline quinone seems to be particularly involved in regulating cell signaling pathways that promote metabolic and mitochondrial processes in many experimental contexts,thus dictating the rationale to consider pyrroloquinoline quinone as a vital compound for mammalian *** the regulation of different metabolic mechanisms,pyrroloquinoline quinone may improve clinical deficits where dysfunctional metabolism and mitochondrial activity contribute to induce cell damage and *** quinone has been demonstrated to have neuroprotective properties in different experimental models of neurodegeneration,although the link between pyrroloquinoline quinone-promoted metabolism and improved neuronal viability in some of such contexts is still to be fully ***,we review the general properties of pyrroloquinoline quinone and its capacity to modulate metabolic and mitochondrial mechanisms in physiological *** addition,we analyze the neuroprotective properties of pyrroloquinoline quinone in different neurodegenerative conditions and consider future perspectives for pyrroloquinoline quinone’s potential in health and disease.

关键词： metabolism mitochondria neurodegenerative disease neuroprotection pyrroloquinoline quinone retinal diseases

Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia s.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National science Foundation(NsF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

Combinatorial therapies for spinal cord injury repair

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Neural Regeneration Research 2025年第5期20卷 1293-1308页

作者： Carla s.sousa Andreia Monteiro António j.salgado Nuno A.silva Life and Health sciences Research Institute(ICVs) School of MedicineUniversity of MinhoCampus de Gualtar-gualtarBragaPortugal ICVs/3B’s Associate Lab PT Government Associated LabCampus de Gualtar-gualtarBragaPortugal

spinal cord injuries have profound detrimental effects on individuals, regardless of whether they are caused by trauma or non-traumatic events. The compromised regeneration of the spinal cord is primarily attributed to damaged neurons, inhibitory molecules, dysfunctional immune response, and glial scarring. Unfortunately, currently, there are no effective treatments available that can fully repair the spinal cord and improve functional outcomes. Nevertheless, numerous pre-clinical approaches have been studied for spinal cord injury recovery, including using biomaterials, cells, drugs, or technological-based strategies. Combinatorial treatments, which target various aspects of spinal cord injury pathophysiology, have been extensively tested in the last decade. These approaches aim to synergistically enhance repair processes by addressing various obstacles faced during spinal cord regeneration. Thus, this review intends to provide scientists and clinicians with an overview of pre-clinical combinatorial approaches that have been developed toward the solution of spinal cord regeneration as well as update the current knowledge about spinal cord injury pathophysiology with an emphasis on the current clinical management.

关键词： electric stimulation neural tissue regeneration neuroprotection polytherapy spinal cord injury

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William j.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh s.Nugent Uniformed services University of the Health sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

Petrographic and sHRIMP studies of Zircons fromthe Caledonian Xiongdian Eclogite, NorthwesternDabie Mountains

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Acta Geologica sinica(English Edition) 2000年第4期74卷 766-773页

作者： I.s.williams Australian National University G.P.O Box 4 Canberra A.C.T. 2601 Australia

The Xiongdian eclogite occurring in the sujiahe tectonic melange zone at Luoshan County, Henan Province, in the western Dabie Mountains, is typical high-pressure (HP)-ultrahigh-pressure (UHP) and medium-temperature eclogite. The occurrence, internal texture and surface characteristics of zircons in eclogite were studied rather systematically petrographically combined with the cathodoluminescence (CL) and scanning electron microscope (sEM) methods. Zircons are mainly hosted in garnet and other metamorphic minerals with sharp boundaries, have a multifaceted morphology and are homogeneous or exhibit a metamorphic growth texture in the interior, thus indicating that they are the product of metamorphism. sHRIMP analyses give zircon 206Pb/238U ages of 335 to 424 Ma and show a certain degree of radiogenic Pb loss; therefore it may be inferred that the age of 424? Ma represents the minimum age of a HP-UHP metamorphic age. From the above analyses coupled with previous sm-Nd, 40Ar-39Ar, U-Pb and 207Pb/206Pb age data, it is suggested that the peak metamorphic age of the Xiongdian eclogite should be between 424 and 480 Ma. This study further validate the view of the existence of a Caledonian HP-UHP metamorphic event in the western Dabie Mountains.

关键词： Dabie Mountains Caledonian eclogite sHRIMP analysis

A systematic review of progenitor survival and maturation in Parkinsonian models

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Neural Regeneration Research 2025年第11期20卷 3172-3178页

作者： Giulia Comini Eilís Dowd Pharmacology&Therapeutics and Galway Neuroscience Center University of GalwayGalwayIreland

stem cell-based brain repair is a promising emergent therapy for Parkinson's disease based on years of foundational research using human fetal donors as a cell *** current therapeutic options for patients,this approach has the potential to provide longterm stem cell–derived reconstruction and restoration of the dopaminergic input to denervated regions of the brain allowing for restoration of certain functions to *** ultimate clinical success of stem cell–derived brain repair will depend on both the safety and efficacy of the approach and the latter is dependent on the ability of the transplanted cells to survive and differentiate into functional dopaminergic neurons in the Parkinsonian *** the pre-clinical literature suggests that there is considerable variability in survival and differentiation between studies,the aim of this systematic review was to assess these parameters in human stem cell-derived dopaminergic progenitor transplant studies in animal models of Parkinson's disease.A defined systematic search of the PubMed database was completed to identify relevant studies published up to March *** screening,76 articles were included in the analysis from which 178 separate transplant studies were *** these,graft survival could be assessed in 52 studies and differentiation in 129 ***,we found that graft survival ranged froms transplanted,with a median of 51%of transplanted cells surviving in the brain;while dopaminergic differentiation of the cells ranged from 0% to 46% of cells transplanted with a median of 3%.This systematic review suggests that there is considerable scope for improvement in the differentiation of stem cell-derived dopaminergic progenitors to maximize the therapeutic potential of this approach for patients.

关键词： cell replacement therapy differentiation embryonic stem cells graft induced pluripotent stem cells Parkinson's disease survival transplant

Effect of nanoparticle(Pd, Pd/Pt, Ni) deposition on high temperature hydrogenation of Ti-V alloys in gaseous flow containing CO

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Progress in Natural science:Materials International 2017年第1期27卷 93-98页

作者： s.suwarno M.williams j.K.solberg V.A.Yartys Department of Mechanical Engineering Institut Teknologi Sepuluh Nopember Department of Materials science and Engineering NTNU Institute for Energy Technology University of the Western Cape

The hydrogenation properties of Ti-V hydrides coated with nanoparticles have been studied in gaseous mixtures of argon and hydrogen with and without additions of 1% CO. Nanoparticles of Pd, Ni, and co-deposited Pd/Pt with particle sizes of;0–60 nm were formed by electroless deposition on the hydride surfaces. The alloy resistance to CO could be significantly improved by particle deposition. Large amounts of hydrogen were absorbed in a CO-containing gas when Ni and Pd/Pt deposition had been applied, while pure Pd deposition had no positive effect. Ni was found to have a stronger effect than those of Pd/Pt and Pd, possibly because of the size effect of Ni nanoparticles.

关键词： Metal hydride Titanium Vanadium Nanoparticle Palladium Nickel Platinum Carbon monoxide