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牵张成骨修复颅骨缺损对硬脑膜组织力学性能的影响

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中国组织工程研究与临床康复 2007年第32期11卷 6338-6341页

作者：周海孝余墨声胡静戚孟春武汉大学人民医院整形外科湖北省武汉市430060 四川大学华西口腔医学院四川省成都市610060

目的:观察牵张成骨修复颅骨缺损过程中硬脑膜组织力学性能的变化。方法:实验于2006-03/12在武汉大学人民医院外科实验室完成。①实验材料:选用健康清洁级山羊30只,18～24个月龄,体质量18～20kg,性别不限,由武汉大学医学院实验动物中心提... 详细信息

目的:观察牵张成骨修复颅骨缺损过程中硬脑膜组织力学性能的变化。方法:实验于2006-03/12在武汉大学人民医院外科实验室完成。①实验材料:选用健康清洁级山羊30只,18～24个月龄,体质量18～20kg,性别不限,由武汉大学医学院实验动物中心提供(SCXK(鄂)2003-2004)。②实验方法:将山羊单纯随机分为6组:7d组(牵张第7天),固定0,2,4,8周组,正常对照组,每组5只。取实验组山羊25只,切开颅顶,暴露颅顶区骨面,裂钻行10mm×25mm颅骨切开,仔细分离硬脑膜,移去骨块,形成骨缺损,建立颅骨缺损牵张模型。延迟7d后开始牵张,牵张速率为0.8mm/d,2次/d,每次0.4mm,间隔12h,总牵张距离10mm。分别于牵张中(牵张第7天)、牵张结束当天(固定期第0周)、固定期第2,4,8周处死动物,处死后将各组动物沿牵张区外5mm切取硬脑膜组织20mm×30mm。正常对照组5只动物不实施手术,取同样大小颅顶区硬脑膜组织。③实验评估:标本修整后分别沿牵张方向和垂直牵张方向切成长宽比为5∶1的窄条形试件,浸入人工脑脊液直接送实验室,进行单向拉伸实验和拉伸蠕变实验,观察硬脑膜弹性模量和在相同载荷条件下应变值变化。结果:30只山羊全部进入结果分析。①不同时期两个方向硬脑膜组织弹性模量变化:不同时期两个方向硬脑膜组织弹性模量:沿牵张方向硬脑膜弹性模量在牵张期逐渐增加,至固定期第2周最大,以后逐渐下降,至固定期第8周接近正常;在垂直牵张方向上,硬脑膜弹性模量值无明显变化。②不同时间硬脑膜在相同载荷条件下的应变值变化:当突然加载荷时有一初始变形,随后在该载荷作用下标本的变形随时间变形缓慢增加,但幅度很小。正常对照组初始应变值ε约为0.03,牵张中、末应变值变化与正常对照组一致,固定第2,4周ε增加,至第8周趋于正常。结论:硬脑膜组织在牵张过程中出现适应性改建,牵张成骨修复颅骨缺损对硬脑膜组织力学性能无不良影响。

关键词：牵张成骨颅骨缺损硬脑膜

Prior-based Bayesian information criterion

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Statistical Theory and related Fields 2019年第1期3卷 2-13页

作者： M.j.Bayarria james O.Berger Woncheol jang Surajit ray Luis r.Pericchi Ingmar Visser Department of Statistics and Operations research University of ValenciaValenciaSpain Department of Statistical Science Duke UniversityDurhamNCUSA Department of Statistics Seoul National UniversitySeoulKorea School of Mathematics and Statistics University of GlasgowGlasgowUK Department of Mathematics University of Puerto RicoSan JuanPuerto Rico Department of Psychology University of AmsterdamAmsterdamNetherlands

We present a new approach to model selection and Bayes factor determination,based on Laplaceexpansions(as in BIC),which we call Prior-based Bayes Information Criterion(PBIC).In thisapproach,the Laplace expansion is only done with the likelihood function,and then a suitableprior distribution is chosen to allow exact computation of the(approximate)marginal likelihoodarising from the Laplace approximation and the *** result is a closed-form expression similar to BIC,but now involves a term arising from the prior distribution(which BIC ignores)andalso incorporates the idea that different parameters can have different effective sample sizes(whereas BIC only allows one overall sample size n).We also consider a modification of PBIC whichis more favourable to complex models.

关键词： Bayes factors model selection Cauchy priors consistency effective sample size Fisher information Laplace expansions robust priors

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深海环境海洋生态系统监测与修复新技术

Engineering 2024年第3期34卷 195-211页

作者： jacopo Aguzzi Laurenz Thomsen Sascha Flögel Nathan j.robinson Giacomo Picardi Damianos Chatzievangelou Nixon Bahamon Sergio Stefanni jordi Grinyó Emanuela Fanelli Cinzia Corinaldesi joaquin Del rio Fernandez Marcello Calisti Furu Mienis Elias Chatzidouros Corrado Costa Simona Violino Michael Tangherlini roberto Danovaro Instituto de Ciencias del Mar(ICM-CSIC) Barcelona 08003Spain Stazione Zoologica Anton Dohrn Naples 80121Italy University of Gothenburg Göteborg 40530Sweden GEOMAr Helmholtz Centre for Ocean research Kiel 24148Germany Fundación Oceanogràfic de la Comunitat Valenciana Valencia 46013Spain royal Netherlands Institute for Sea research(NIOZ) Den Burg Texel 1790 ABNetherlands Polytechnic University of Marche(UNIVPM) Ancona 60131Italy SArTI-MAr of the Universitat Politecnica de Catalunya(UPC) Vilanova i la Geltrú08800Spain Lincoln Institute for Agri-food Technology University of LincolnLincoln LN22LGUK Engitec Systems International Limited Limassol 3083Cyprus Consiglio per la ricerca in Agricoltura e L’analisi Dell’economia Agraria(CrEA) Centro di Ricerca Ingegneria e Trasformazioni AgroalimentariMonterotondo 00015Italy

The United Nations(UN)’s call for a decade of“ecosystem restoration”was prompted by the need to address the extensive impact of anthropogenic activities on natural *** ecosystem restoration is increasingly necessary due to increasing habitat degredation in deep waters(>200 m depth).At these depths,which are far beyond those accessible by divers,only established and emerging robotic platforms such as remotely operated vehicles(rOVs),autonomous underwater vehicles(AUVs),landers,and crawlers can operate through manipulators and multiparametric sensor arrays(e.g.,optoacoustic imaging,omics,and environmental probes).The use of advanced technologies for deep-sea ecosystem restoration can provide:①high-resolution three-dimensional(3D)imaging and acoustic mapping of substrates and key taxa,②physical manipulation of substrates and key taxa,③real-time supervision of remote operations and long-term ecological monitoring,and④the potential to work ***,we describe how robotic platforms with in situ manipulation capabilities and payloads of innovative sensors could autonomously conduct active restoration and monitoring across large spatial *** expect that these devices will be particularly useful in deep-sea habitats,such as①reef-building cold-water corals,②soft-bottom bamboo corals,and③soft-bottom fishery resources that have already been damaged by offshore industries(i.e.,fishing and oil/gas).

关键词： Ecosystem restoration robotic manipulation Acoustic tracking Fishery resources Artificial reefs

Endovascular treatment in anterior circulation stroke beyond 6.5 hours after onset or time last seen well:results from the Mr CLEAN registry

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Stroke & Vascular Neurology 2021年第4期6卷 572-580,I0037-I0048页

作者： Luuk Dekker Esmee Venema F Anne V Pirson Charles B L M Majoie Bart j Emmer Ivo G H jansen Maxim j H L Mulder robin Lemmens robert-jan B Goldhoorn Marieke j H Wermer jelis Boiten Geert j LycklamaàNijeholt Yvo B W E M roos Adriaan C G M van Es Hester F Lingsma Diederik W j Dippel Wim H van Zwam robert j van Oostenbrugge Ido r van den Wijngaard on behalf of the Mr CLEAN registry investigators Neurology Leiden University Medical CentreLeidenThe Netherlands Neurology Erasmus MCRotterdamThe Netherlands Public Health Erasmus MCRotterdamThe Netherlands Neurology Maastricht University Medical Centre+MaastrichtThe Netherlands radiology and Nuclear Medicine Amsterdam University Medical CentreLocation AMCAmsterdamThe Netherlands Neurology University Hospitals LeuvenLeuvenBelgium Neurosciences Experimental Neurology and Leuven Brain InstituteUniversity of LeuvenLeuvenBelgium VIB Center for Brain&Disease ResearchLaboratory of NeurobiologyLeuvenBelgium Neurology Haaglanden Medical CentreDen HaagThe Netherlands radiology Haaglanden Medical CentreDen HaagThe Netherlands Neurology Amsterdam University Medical CentreLocation AMCAmsterdamThe Netherlands radiology Leiden University Medical CentreLeidenThe Netherlands radiology Maastricht University Medical Centre+MaastrichtThe Netherlands

Background randomised controlled trials with perfusion selection have shown benefit of endovascular treatment(EVT)for ischaemic stroke between 6 and 24 hours after symptom onset or time last seen ***,outcomes after EVT in these late window patients without perfusion imaging are largely *** assessed their characteristics and outcomes in routine clinical *** The Multicenter randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands registry,a prospective,multicentre study in the Netherlands,included patients with an anterior circulation occlusion who underwent EVT between 2014 and *** perfusion was no standard imaging *** used adjusted ordinal logistic regression analysis to compare patients treated within versus beyond 6.5 hours after propensity score matching on age,prestroke modified rankin Scale(mrS),National Institutes of Health Stroke Scale,Alberta Stroke Programme Early CT Score(ASPECTS),collateral status,location of occlusion and treatment with intravenous *** included 3-month mrS score,functional independence(defined as mrS 0-2),and *** Of 3264 patients who underwent EVT,106(3.2%)were treated beyond 6.5 hours(median 8.5,IQr 6.9-10.6),of whom 93(87.7%)had unknown time of stroke *** perfusion was not performed in 87/106(80.2%)late window *** window patients were younger(mean 67 vs 70 years,pr ASPECTS(median 8 vs 9,pr collateral status(collateral score 2-3:68.3%vs 57.7%,p=0.03).No differences were observed in proportions of functional independence(43.3%vs 40.5%,p=0.57)or death(24.0%vs 28.9%,p=0.28).After matching,outcomes remained similar(adjusted common Or for 1 point improvement in mrS 1.04,95%CI 0.56 to 1.93).Conclusions Without the use of CT perfusion selection criteria,EVT in the 6.5-24-hour time window was not associated with poorer outcome in selected patients with favourable clinical and CT/C

关键词： treatment beyond registry

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微网协调保护控制及自动化方案

华东电力 2009年第3期37卷 518-518页

作者： r M Tumilty I M Elders G M Burt j r mc-Donald

允许分布式电源（DG）进行微网运行还可以获得技术和经济利益，微网能够满足用户对电能质量和可靠性的要求，微网还可以实现有功、无功控制，减少电网电压失落，校正系统不平衡等功能。虽然微网可能提供如此多的好处，实现微网仍面临许... 详细信息

允许分布式电源（DG）进行微网运行还可以获得技术和经济利益，微网能够满足用户对电能质量和可靠性的要求，微网还可以实现有功、无功控制，减少电网电压失落，校正系统不平衡等功能。虽然微网可能提供如此多的好处，实现微网仍面临许多挑战，其中微网保护就是其中尤其重要的挑战，一旦微网形成，就要使负载、线路、DG都得到保护。

关键词：保护控制自动化方案微网分布式电源经济利益电能质量无功控制电网电压

Stagnant lid tectonics:Perspectives from silicate planets,dwarf planets, large moons,and large asteroids

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Geoscience Frontiers 2018年第1期9卷 103-119页

作者： robert j.Stern Taras Gerya Paul j.Tackley Geosciences Department University of Texas at Dallas Department of Earth Sciences ETH-Zurich

To better understand Earth's present tectonic style-plate tectonics—and how it may have evolved from single plate(stagnant lid) tectonics, it is instructive to consider how common it is among similar bodies in the Solar System. Plate tectonics is a style of convection for an active planetoid where lid fragment(plate) motions reflect sinking of dense lithosphere in subduction zones, causing upwelling of asthenosphere at divergent plate boundaries and accompanied by focused upwellings, or mantle plumes;any other tectonic style is usefully called "stagnant lid" or "fragmented lid". In 2015 humanity completed a 50+ year effort to survey the 30 largest planets, asteroids, satellites, and inner Kuiper Belt objects,which we informally call "planetoids" and use especially images of these bodies to infer their tectonic activity. The four largest planetoids are enveloped in gas and ice(jupiter, Saturn, Uranus, and Neptune)and are not considered. The other 26 planetoids range in mass over 5 orders of magnitude and in diameter over 2 orders of magnitude, from massive Earth down to tiny Proteus; these bodies also range widely in density, from 1000 to 5500 kg/m^3. A gap separates 8 silicate planetoids with ρ = 3000 kg/m^3 or greater from 20 icy planetoids(including the gaseous and icy giant planets) with ρ = 2200 kg/m^3 or less. We define the "Tectonic Activity Index"(TAI), scoring each body from 0 to 3 based on evidence for recent volcanism, deformation, and resurfacing(inferred from impact crater density). Nine planetoids with TAI = 2 or greater are interpreted to be tectonically and convectively active whereas 17 with TAI re inferred to be tectonically dead. We further infer that active planetoids have lithospheres or icy shells overlying asthenosphere or water/weak ice. TAI of silicate(rocky) planetoids positively correlates with their inferred rayleigh number. We conclude that some type of stagnant lid tectonics is the dominant mode of heat loss and that plate tectonics

关键词： Stagnant lid Solar system Plate tectonics Planets Moons

经静脉注射碘克沙醇与急性肾损伤、渗漏和死亡率风险增高相关吗?一项校正后倾向性评分研究

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国际医学放射学杂志 2018年第1期 91-91页

作者： j.S.mc Donald r.j.mc Donald E.E.Williamson D.F.Kallmes 张俊峰 Department of radiology Mayo Clinic

摘要目的比较平扫和经静脉注射碘克沙醇行增强CT检查后病人急性肾损伤、急性渗漏和短期死亡的发生率。材料与方法研究设计和实施已获得机构伦理委员会批准并符

关键词：肾损伤 CT 碘克沙醇静脉注射倾向性评分

White (Trifolium repensL.) and Arrowleaf (Trifolium vesiculosumSavi) Clover Emergence in Varying Loblolly Pine (Pinus taedaL.) Tree Alley Spacings

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American journal of Plant Sciences 2019年第4期10卷 659-669页

作者： Taylor C.Adams Dirk Philipp David M.Burner john jennings Becky mc Peake Amanda j.Ashworth Daniel H.Pote joan M.Burke robert rhein Department of Poultry Science University of ArkansasFayettevilleARUSA Animal Science Department University of ArkansasFayettevilleARUSA retired US Department of AgricultureDale Bumpers Small Farms Research CenterBoonevilleARUSA Cooperative Extension Service University of ArkansasLittle RockARUSA US Department of Agriculture Poultry Production and Product Safety Research UnitFayettevilleARUSA US Department of Agriculture Dale Bumpers Small Farms Research CenterBoonevilleARUSA

Agroforestry systems have the potential to provide year-long income opportunities via the integrated forage or crop, timber, and livestock. Legumes are an attractive alternative option during the growing season when more traditional forages may not be as productive. The objective of this study was to test the establishment of arrowleaf and white clover grown under varying pine tree alley widths. In 2011, existing forage was removed in 15-yr old loblolly pine tree row alleys of different widths (3.7, 4.9, 7.3, and 9.8 m), including an open area. Arrowleaf, as an annual, was replanted in 2012. Seedlings were counted twice/year, while dry matter was measured three times/year. Photosynthetically active radiation (PAr) was measured in all alley widths to compare light penetration through the canopy. Hot and dry conditions occurred throughout 2012, affecting results. In 2012 and 2013, the greatest PAr for most treatments was observed in june. Seedling counts for all treatments were greatest immediately after establishment, and gradually declined throughout the course of the study. Dry matter yields increased throughout the growing season, and were greatest in arrowleaf clover in the open area on all measurement dates;however, increased weed pressure and repeated flooding affected yields. This study demonstrated that clover establishment in shady wooded areas is possible, but only under suitable environmental conditions.

关键词： White Clover Arrowleaf Clover Dry Matter Yield Seedling Count Agroforestry

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加拿大贝尔德莫雷-杰拉尔顿地区的金矿化

华北地质 1988年第1期 74-82页

作者： j. K. Mason C. D. mc Connell 李上森

引言贝尔德莫雷-杰拉尔顿地区位于安大略图恩德尔湾东北160-275km的尼皮干(Ni-pigon)湖的东边。该区有18个金矿,已有50多年生产金的历史。这些金矿中最大的包括马克利奥德-科马舒特(Macleod-Cockshutt)、利特思(Leitch),小隆来、联合的... 详细信息

引言贝尔德莫雷-杰拉尔顿地区位于安大略图恩德尔湾东北160-275km的尼皮干(Ni-pigon)湖的东边。该区有18个金矿,已有50多年生产金的历史。这些金矿中最大的包括马克利奥德-科马舒特(Macleod-Cockshutt)、利特思(Leitch),小隆来、联合的莫舍金矿(Consolidated Mosher)、哈德洛克、马格尼特联合金矿、北恩派尔

关键词：金矿床贵金属矿床金矿化石英脉容矿岩石变火山岩变质火山岩变质岩铁岩杰拉尔顿花岗闪长岩酸性岩黄铁矿铁矿物贝尔德钠长斑岩金矿区碳酸盐化岩石类型岩石分类莫雷