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International Soil and Water Conservation Research 2023年第4期11卷 688-699页

作者： Valentin Landemaine Olivier Cerdan Thomas Grangeon Rosalie Vandromme Benoit Laignel Olivier Evrard Sébastien Salvador-Blanes j.patrick Laceby BRGM F-45060OrléansFrance University of Rouen M2CRouenFrance Laboratoire des Sciences du Climat et de l'Environnement(LSCE/IPSL) UnitéMixte de Recherche 8212(CEA/CNRS/UVSQ)UniversitéParis-SaclayGif-sur-YvetteFrance University of Tours UR 6293-GéoHydrosystèmes Continentaux(GEHCO)France Alberta Environment and Protected Areas CalgaryCanada

A major challenge in runoff and soil erosion modelling is the adequate representation of the most relevant processes in models while avoiding over *** the European loess belt,pro-gressive soil crusting during rainfall events,resulting in infiltration-excess runoff,is usually considered the dominant process generating runoff on catchments covered with silty ***-excess may also occur and affect their runoff and erosion ***,saturation-excess runoff occurrence and quantification have rarely been performed and is usually not taken into account when modelling runoff and erosion in these ***,a continuous simulation of the Austreberthe catchment(214 km^(2)),located in the European loess belt(Normandy,France),was conducted with the new Water and Sediment(WaterSed)model over 12 years,corresponding to more than 780 individual rainfall events,at a 25 m spatial *** inter-annual variability of runoff and erosion was closely linked to the number of intense events per year and their distribution through the *** model was properly calibrated over a representative set of 35 rainfall events,considering either infiltration-excess and/or saturation-excess *** was also able to reproduce the measured runoff volume for most of the monitoring ***,the three years with most rainfall were adequately modelled only including saturation-excess *** analysis performed at the seasonal scale revealed that saturation was modelled in the catchment during almost all of the modelling period,suggesting the importance of this often overlooked process in current modelling attempts.

关键词： European loess belt Soil erosion Saturation-excess runoff WaterSed model

The immune tolerant phase of chronic HBV infection： new perspectives on an old concept

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Cellular & Molecular Immunology 2015年第3期12卷 258-263页

作者： Antonio Bertoletti patrick T kennedy Emerging Infectious Diseases (EID) Program Duke-NUS Graduate Medical School Singapore Viral Hepatitis Laboratory Singapore Institute for ClinicalSciences Agency of Science Technology and Research (A＊STAR) Singapore and Blizard Institute Barts and The London School of Medicine & DentistryLondon UK

Chronic hepatitis B virus （HBV） infection progresses through distinct disease phases that are strongly associated with patient age. The so-called immune tolerant （IT） phase represents the classical early phase of infection; it is associated with high levels of HBV replication and lack of clinical signs of liver Inflammation. Whether this phase of HBV infection is also associated with immunological features of ＂tolerance＇ has recently been challenged. Here, we review the data that dispute this concept of immune tolerance and then propose an alternative interpretation of the immunopathological events that take place during this early phase of CHB infection.

关键词： Hepatitis B antiviral immunity T cells

Preoperative gastric retention in endoscopic retrograde cholangiopancreatography

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World journal of Gastrointestinal Surgery 2024年第11期16卷 3632-3635页

作者： Alkiviadis Efthymiou patrick T kennedy Department of Gastroenterology St Luke’s HospitalThessaloniki 54623Greece Liver Centre Blizard InstituteBarts and The London School of Medicine and DentistryQMULLondon E12ADUnited Kingdom

We comment on the article by jia et al,in the World journal of Gastrointestinal *** focus mainly on the factors that impair gastric motility and cause gastric retention in the pre-operative setting of endoscopic retrograde cholan-giopancreatography(ERCP).ERCP is a complex endoscopic therapeutic proce-dure,which demands great skill from the endoscopist but also has recognized *** retention impairs the endoscopist’s visibility but also increases the risk of complications,such as aspiration ***,identifying the factors that predispose to gastric retention alerts the endoscopists of the possible risks and enables them to take evasive *** authors in the current study by jia et al developed and validated a predictive model,which in-corporates five different factors,i.e.,gender,primary disease,jaundice,opioid use,and gastrointestinal obstruction,which were found to influence gastric *** model was shown to have a high predictive value to accurately identify pa-tients at risk for gastric retention before a therapeutic ERCP.

关键词： Gastric retention Endoscopic retrograde cholangiopancreatography Predic-tive model Malignant gastroparesis

九寨沟长海中心纲硅藻的分类学研究及报道1个新种（英文）

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水生生物学报 2017年第5期41卷 1140-1148页

作者：徐季雄尤庆敏 KOCIOLEK j.patrick 王全喜上海师范大学生命科学与环境学院上海200234 Museum of Natural History and Department of Ecology and Evolutionary Biology University of Colorado

研究报道了采自中国四川九寨沟自然保护区长海的4种中心类硅藻种类,其中新种1个:长海小环藻(Cyclotella changhai ***.),中国新记录种1个:克里特小环藻(***)和2种较少报道的种类:可辨小环藻(***)和辐纹琳达藻(Lindavia radiosa)。通过... 详细信息

研究报道了采自中国四川九寨沟自然保护区长海的4种中心类硅藻种类,其中新种1个:长海小环藻(Cyclotella changhai ***.),中国新记录种1个:克里特小环藻(***)和2种较少报道的种类:可辨小环藻(***)和辐纹琳达藻(Lindavia radiosa)。通过光学显微镜和扫描电子显微镜对这4个种类形态学的特征进行观察,并与相似种类进行比较。与长海小环藻相似的种类包括*** Grunow,*** Scheffler和*** Druart&Straub,主要通过壳面中央区的不同形态进行区分-长海小环藻的中央区近平滑且具有不规则的凹陷。

关键词：中心纲硅藻小环藻琳达藻九寨沟中国新种分类

The role of crystallinity on differential attachment/ proliferation of osteoblasts and fibroblasts on poly （caprolactone-co-glycolide） polymeric surfaces

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Frontiers of Materials Science 2012年第1期6卷 47-59页

作者： Helen CUI patrick j.SINKO Advanced Technology and Regenerative Medicine(ATRM) LLCSomervilleNJ 08876USA Department of Pharmaceutics Ernest Mario School of PharmacyRutgersThe State University of New JerseyPiscatawayNJ 08854USA

The objective of the present study is to systematically evaluate the role of polymer crystallinity on fibroblast and osteoblast adhesion and proliferation using a series of poly（caprolactone-co-glycolide）（PCL/PGA） polymers. PCL/PGA polymers were selected since they reflect both highly crystalline and amorphous materials. PCL/PGA polymeric materials were fabricated by compression molding into thin films. Five compositions, from PCL or PGA to intermediate copolymeric compositions of PCL/PGA in ratios of 25：75, 35：65 and 45：55, were studied. Pure PCL and PGA represented the crystalline materials while the copolymers were amorphous. The polymers/copolymers were characterized using DSC to assess crystallinity, contact angle measurement for hydrophobicity, and AFM for nanotopography. The PCL/PGA films demonstrated similar hydrophobicity and nanotopography whereas they differed significantly in crystallinity. Cell adhesion to and proliferation on PCL/PGA films and proliferation studies were performed using osteoblasts and NIH-3T3 fibroblasts. It was observed that highly crystalline and rigid PCL and PGA surfaces were significantly more efficient in supporting fibroblast growth, whereas amorphous/flexible PCL/PGA 35：65 was significantly more efficient in supporting growth of osteoblasts. This study demonstrated that while chemical composition, hydrophobicity and surface roughness of PCL/PGA polymers were held constant, crystallinity and rigidity of PCL/PGA played major roles in determining cell responses.

关键词： crystallinity attachment proliferation osteoblast fibroblast PCL-PGA

On the Dirichlet form of three-dimensional Brownian motion conditioned to hit the origin

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Science China Mathematics 2019年第8期62卷 1477-1492页

作者： patrick j. Fitzsimmons Liping Li Department of Mathematics University of California at San Diego San Diego CA 92093-0112 USA RCSDS HCMS Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China

Our concern in this paper is the energy form induced by an eigenfunction of a self-adjoint extension of the restriction of the Laplace operator to C_c^∞(R^3\{0}).We will prove that this energy form is a regular Dirichlet form with core C_c^∞(R^3).The associated diffusion X behaves like a 3-dimensional Brownian motion with a mild radial drift when far from 0,subject to an ever-stronger push toward 0 near that *** particular,{0}is not a polar set with respect to *** diffusion X is rotation invariant,and admits a skew-product representation before hitting{0}:its radial part is a diffusion on(0,∞)and its angular part is a time-changed Brownian motion on the sphere S^*** radial part of X is a"reflected"extension of the radial part of X^0(the part process of X before hitting{0}).Moreover,X is the unique reflecting extension of X^0,but X is not a semi-martingale.

关键词： Dirichlet form reflected extension rotationally invariant process Fukushima’s decomposition

Adaptive optics in laser processing

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Light(Science & Applications) 2019年第1期8卷 140-155页

作者： patrick S.Salter Martin j.Booth Department of Engineering Science University of OxfordParks RoadOxford OX13PJUK

Adaptive optics are becoming a valuable tool for laser processing,providing enhanced functionality and flexibility for a range of *** a single adaptive element,it is possible to correct for aberrations introduced when focusing inside the workpiece,tailor the focal intensity distribution for the particular fabrication task and/or provide parallelisation to reduce processing *** is particularly promising for applications using ultrafast lasers for threedimensional *** review recent developments in adaptive laser processing,including methods and applications,before discussing prospects for the future.

关键词： laser optics workpiece

Explaining Hong Kong Students’International Achievement in Civic Learning

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Frontiers of Education in China 2016年第3期11卷 299-321页

作者： Kerry j.kennedy LI Lijuan Centre for Governance and Citizenship The Education University of Hong KongHong KongChina Faculty of Education The University of JohannesburgJohannesburgSouth Africa

This study identifies predictors of Hong Kong students’civic *** has adopted a cross-sectional quantitative design using secondary data from the 2009 International Civics and Citizenship Education Study(ICCS 2009;Schulz et al.,2010).Multi-level analysis reveals that most of the variance in student achievement can be accounted for by school level rather than individual level *** background variables are largely insignificant suggesting the resilience of many Hong Kong *** Hong Kong students’achievements in civic learning,a possible explanation is made and implications are developed for both theory and practice.

关键词： political socialization civic learning agents school context multi-level analysis

The Global Boundary Stratotype Section and Point for the base of the Turonian Stage of the Cretaceous： Pueblo, Colorado, U.S.A.

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Episodes 2005年第2期28卷 93-104页

作者： W.j.kennedy I.Walaszczyk W.A.Cobban GeologicalCollections OxfordUniversityMuseumofNaturalHistoryParksRoadOxfordOXl3PWUnitedKingdom InstituteofGeologyoftheUniversityofWarsaw A1.ZwirkiIWigury9302-089WarszawaPoland 70EstesStreet LakewoodColorado80226USA

Following the recommendation of the International Commission on Stratigraphy (16 votes Yes [94%], 1 abstention, 2 votes not received), the Global boundary Stratotype Section and Point (GSSP) for the base of the Turonian Stage of the Cretaceous System is defined as the base of bed 86 of the Bridge Creek Limestone Member of the Greenhorn Limestone Formation at the western end of the Denver and Rio Grande Railroad cut near the north boundary of the Pueblo Reservoir State Park Recreation Area, west of Pueblo, Colorado, USA. This GSSP horizon is also exposed and protected in the adjacent state recreation area. It coincides with the first occurrence of the ammonite Watinoceras devonense, is in the middle of a global positive excursion in Carbon-13 isotopes, and is bracketed by widespread bentonites that have yield edages of 93 to 93.5 Ma.

关键词：土仑统白垩纪美国地质分层研究科罗拉多州