检索结果-南通市图书馆

World journal of Gastroenterology 2006年第48期12卷 7810-7814页

作者： Pierre Ingrand jérme Gournay Pierre Bernard Frédéric Oberti Brigitte Bernard-Chabert Arnault Pauwels Philippe Renard Eric Bartoli jean-Franois Cadranel jean-Claude Barbare Isabelle Ingrand Michel Beauchant Clinical Research Center Poitiers University France Hepato-Gastroenterology Centre Hospitalier Universitaire Nantes France Hepato-Gastroenterology Centre Hospitalier Universitaire Saint-André Bordeaux France Hepato-Gastroenterology Centre Hospitalier Universitaire Angers France Hepato-Gastroenterology Centre Hospitalier Universitaire Reims France Hepato-Gastroenterology Centre Hospitalier Gonesse France Hepato-Gastroenterology Centre Hospitalier Argenteuil France Hepato-Gastroenterology Centre Hospitalier Universitaire Amiens France Hepato-Gastroenterology Centre Hospitalier Creil France Hepato-Gastroenterology Centre Hospitalier Compiègne France Hepato-Gastroenterology Centre Hospitalier Universitaire Poitiers France

AIM: To investigate the conformity of management practices of gastrointestinal hemorrhage in cirrhotic patients with relevant guidelines. meTHODS: A questionnaire on the management of digestive bleeding was completed for all consecutive cirrhotic patients admitted to 31 French hospitals. RESULTS: One hundred and twenty-six bleeding events were recorded. It was the first bleeding episode in 79 patients (63%), of whom 40 (51%) had a prior diagnosis of cirrhosis and 25 (32%) had previously undergone an endoscopy. The bleeding episode was a recurrence in 46 patients (37%). The median time between onset and admission was 4 h, but exceeded 12 h in 42% of cases. There was an agreement between centers forearly vasoactive drug administration (87% of cases), association with ligation (42%) more often than sclerosis (21%) at initial endoscopy, and antibiotic prophylaxis (64%). By contrast, prescription of beta-blockade alone or in combination (0 to 100%, P = 0.003) for secondary prophylaxis and lactulose (26% to 86%, P = 0.04), differed among centers. CONCLUSION: In French hospitals, management of bleeding related to portal hypertension in cirrhotic patients is generally in keeping with the consensus. Broad variability still remains concerning beta-blockade use for secondary prophylaxis. Screening for esophageal varices, the use of antibiotic prophylaxis and patients information need to be improved.

关键词： Digestive bleeding Portal hypertension Cirrhosis Evaluation studies

Comparative Study of the Effects of Thermal and Photochemical Accelerated Oxidations on Quality of “Green Type” and “Black Type” French Olive Oils

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American journal of Analytical Chemistry 2016年第12期7卷 890-907页

作者： jérôme Plard Yveline Le Dréau Catherine Rébufa Nathalie Dupuy Aix Marseille Université CNRS IRD Avignon Universit&eacute IMBE UMR 7263 &eacute quipe BEC case 451 Avenue Escadrille Normandie Ni&eacute men 13397 Marseille cedex 20 France

Oxidative stability of two commercial olive oils of different specificity (green type and black type) has been studied during thermal and photochemical accelerated processes through the evolution of quality indices. It might help to assure a good utilisation of olive oil. In most of works described in literature, they are measured individually. In this study, a Principal Component Analysis (PCA) has been performed to emphasize their variation and describe in concise way the quality and the safety of extra-virgin olive oil after two oxidative stresses. No difference had been detected between both type oils when they are heated. Peroxides, aldehydes and conjugated dienes and trienes were formed but rapidly degraded into final oxidation compounds, mainly acid compounds. During the photochemical process, similar changes occurred slower and the green type oil had shown better stability because of its higher phenolic content. The fatty acids had been more impacted (higher disappearance of monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA)) when the oils were heated than when irradiated. Saturated fatty acids (SFA), MUFA and PUFA were the most relevant indicators to characterize non-oxidized oils and PV characterized the early stage of oil oxidation.

关键词： Olive Oil Photo-Oxidation Thermal Oxidation Quality Control Parameters Fatty Acids Phenolic Compounds

Role of (myo)fibroblasts in the development of vascular and connective tissue structure of the C38 colorectal cancer in mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Communications 2018年第1期38卷 488-498页

作者： Edina Bugyik Vanessza Szabó Katalin Dezső András Rókusz Armanda Szücs Péter Nagy józsef Tóvári Viktória László Balázs Döme Sándor Paku First Department of Pathology and Experimental Cancer Research Sem-melweis UniversityBudapestÜllőiút 261085Hungary Department of Experimental Pharmacology National Institute of OncologyBudapest 1122Hungary Department of Thoracic Surgery Semmelweis University-National Institute of OncologyBudapest 1122Hungary. Department of Thoracic Surgery Medical University of ViennaWaehringer Guertel 18-201090 ViennaAustria Department of Biomedical Imaging and Image-guided Therapy Medical University of Vienna1090 ViennaAustria National Koranyi Institute of Pulmonology Budapest 1122Hungary. Tumor Progression Research Group Hungarian Academy of Sciences-Semmelweis UniversityBudapest 1085Hungary

Background:It remains unclear if the vascular and connective tissue structures of primary and metastatic tumors are intrinsically determined or whether these characteristics are defined by the host *** we examined the microanatomical steps of vasculature and connective tissue development of C38 colon carcinoma in different ***:Tumors produced in mice at five different locations(the cecal wall,skin,liver,lung,and brain)were ana-lyzed using fluorescent immunohistochemistry,electron microscopy and quantitative real-time polymerase chain ***:We found that in the cecal wall,skin,liver,and lung,resident fibroblasts differentiate into collagenous matrix-producing myofibroblasts at the tumor *** activated fibroblasts together with the produced matrix were incorporated by the *** connective tissue development culminated in the appearance of intratumoral tissue columns(centrally located single microvessels embedded in connective tissue and smooth muscle actin-expressing myofibroblasts surrounded by basement membrane).Conversely,in the brain(which lacks fibroblasts),C38 metasta-ses only induced the development of vascularized desmoplastic tissue columns when the growing tumor reached the fibroblast-containing ***:Our data suggest that the desmoplastic host tissue response is induced by tumor-derived fibrogenic molecules acting on host tissue *** concluded that not only the host tissue characteristics but also the tumor-derived fibrogenic signals determine the vascular and connective tissue structure of tumors.

关键词： metastasis Vasculature Myofibroblasts Incorporation

Macroalgal deep genomics illuminate multiple paths to aquatic,photosynthetic multicellularity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2024年第5期17卷 747-771页

作者： David R.Nelson Alexandra Mystikou Ashish jaiswal Cecilia Rad-menendez Michael j.Preston Frederik De Boever Diana C.El Assal Sarah Daakour Michael W.Lomas jean-Claude Twizere David H.Green William C.Ratcliff Kourosh Salehi-Ashtiani Division of Science and Math New York University Abu DhabiAbu DhabiUAE Center for Genomics and Systems Biology(CGSB) New York University Abu DhabiAbu DhabiUAE Biotechnology Research Center Technology Innovation InstitutePO Box 9639Masdar CityAbu DhabiUAE Culture Collection of Algae and Protozoa Scottish Association for Marine ScienceObanScotlandUK National Center for Marine Algae and Microbiota Bigelow Laboratory for Ocean SciencesEast BoothbayMEUSA Laboratory of Viral Interactomes GIGA InstituteUniversity of LiegeLiegeBelgium School of Biological Sciences Georgia Institute of TechnologyAtlantaGAUSA

Macroalgae are multicellular,aquatic autotrophs that play vital roles in global climate maintenance and have diverse applications in biotechnology and eco-engineering,which are directly linked to their multicellularity ***,their genomic diversity and the evolutionary mechanisms underlying multicellularity in these organisms remain *** this study,we sequenced 110 macroalgal genomes from diverse climates and phyla,and identified key genomic features that distinguish them from their microalgal *** for cell adhesion,extracellular matrix formation,cell polarity,transport,and cell differentiation distinguish macroalgae from microalgae across all three major phyla,constituting conserved and unique gene sets supporting multicellular *** genes show phylum-and climate-specific expansions that may facilitate niche ***,our study reveals genetic determinants of convergent and divergent evolutionary trajectories that have shaped morphological diversity in macroalgae and provides genome-wide frameworks to understand photosynthetic multicellular evolution in aquatic environments.

关键词： macroalgae multicellularity comparative genomics evolution adhesome endogenous viral elements

Image Acquisition and Parameter Calculations for Optimization of the Automatic Identification of Terpenes in a Combined Laser Thin Film Extract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Materials Physics and Chemistry 2022年第6期12卷 141-154页

作者： Theodore Guié Toa Bi Wognin Vangah Alico Nango jérôme Sié Ouattara Alain Clement UFR Science and Technology University of Man Man Ivory Coast Laboratory of Communication and Information Science and Technology (LSTCI) National Polytechnic Institute Houphou&euml t Boigny Yamoussoukro C&ocirc te d’Ivoire University Institute of Technology of Angers (IUT) Angers France

In this work, we propose an original approach to the thin-layer identification of secondary metabolites (terpenes) based on the acquisition of multicomponent images integrating terpenes to be identified. Its principle consists initially of segmentation by region of each component of the image based on the attribute tuples or colors of each region of the digital image. Then we proceeded to the calculations of region parameters such as standard deviation, entropy, average pixel color, eccentricity from an algorithm on the matlab software. These values allowed us to build a database. Finally, we built an algorithm for identifying secondary metabolites (terpenes) on the basis of these data. The relevance of our method of identifying or recognizing terpenes has been demonstrated compared to other methods, such as the one based on the calculation of frontal ratios which cannot discriminate between two terpenes having the same frontal ratio. The robustness of our method with respect to the identification of linalool, limonene was tested.

关键词： Thin Film Terpenes Segmentation Entropy

High Q and sub-wavelength THz electric field confinement in ultrastrongly coupled THz resonators

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

光子学研究:英文版 2023年第7期11卷 1203-1216页

作者： SIMON meSSELOT SOLEN COEYMANS jEROme TIGNON SUKHDEEP DHILLON jULIETTE MANGENEY Laboratoire de Physique de l’Ecole Normale Supérieure Ecole normale supérieurePSL UniversitySorbonne UniversitéUniversitéParis DiderotSorbonne Paris CitéCNRS24 rue Lhomond75005 ParisFrance

The control of light–matter coupling at the single electron level is currently a subject of growing interest for the development of novel quantum devices and for studies and applications of quantum *** the terahertz(THz)spectral range,this raises the particular and difficult challenge of building electromagnetic resonators that can conciliate low mode volume and high quality ***,we report on hybrid THz cavities based on ultrastrong coupling between a Tamm cavity and an LC circuit metamaterial and show that they can combine high quality factors of up to Q=37 with a deep-subwavelength mode volume of V=3.2×10^(-4)λ^(3).Our theoretical and experimental analysis of the coupled mode properties reveals that,in general,the ultrastrong coupling between a metamaterial and a Fabry–Perot cavity is an effective tool to almost completely suppress radiative losses and,thus,ultimately limit the total losses to the losses in the metallic *** Tamm cavity-LC metamaterial coupled resonators open a route toward the development of single photon THz emitters and detectors and to the exploration of ultrastrong THz light–matter coupling with a high degree of coherence in the few to single electron limit.

关键词： coupling cavity coupled

Network of GRAS transcription factors in plant development,fruit ripening and stress responses

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Horticulture Research 2023年第12期10卷 286-303页

作者： Catarina Neves Beatriz Ribeiro Rute Amaro jesús Expósito jérôme Grimplet Ana Margarida Fortes BioISI-Biosystems and Integrative Sciences Institute Faculty of SciencesUniversity of LisbonCampo Grande1749-016 LisboaPortugal Centro de Investigación y Tecnología Agroalimentaria de Aragón(CITA) Departamento de Ciencia VegetalGobierno de AragónAvda.Montañana 93050059 ZaragozaSpain Instituto Agroalimentario de Aragón-IA2(CITA-Universidad de Zaragoza) Calle Miguel Servet 17750013 ZaragozaSpain

The plant-specific family of GRAS transcription factors has been wide implicated in the regulation of transcriptional reprogramming associated with a diversity of biological functions ranging from plant development processes to stress *** analyses of GRAS transcription factors supported by in silico structural and comparative analyses are emerging and clarifying the regulatory networks associated with their biological *** this review,a detailed analysis of GRAS proteins’structure and biochemical features as revealed by recent discoveries indicated how these characteristics may impact subcellular location,molecular mechanisms,and *** issues associated with GRAS classification into different subfamilies in diverse plant species even in the presence of robust genomic resources are discussed,in particular how it affects assumptions of biological *** into the mechanisms driving evolution of this gene family and how genetic and epigenetic regulation of GRAS contributes to subfunctionalization are ***,this review debates challenges and future perspectives on the application of this complex but promising gene family for crop improvement to cope with challenges of environmental transition.

关键词： function GRAS plant

Eradicating Extreme Poverty,the CPC’s Historic Feat

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Today 2021年第7期70卷 46-48页

作者： jEROme KABORE ***

THE Communist Party of China(CPC)turns 100 in 2021,making it a year of celebration and of historical and symbolic significance for the Chinese *** its leadership,China has achieved spectacular development and succeede... 详细信息

关键词： CPC turns Extreme

Layer-controlled nonlinear terahertz valleytronics in two-dimensional semimetal and semiconductor PtSe_(2)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

InfoMat 2023年第11期5卷 49-63页

作者： Minoosh Hemmat Sabrine Ayari Martin Micica Hadrien Vergnet Shasha Guo mehdi Arfaoui Xuechao Yu Daniel Vala Adrien Wright Kamil Postava juliette Mangeney Francesca Carosella Sihem jaziri Qi jie Wang Zheng Liu jérôme Tignon Robson Ferreira Emmanuel Baudin Sukhdeep Dhillon Laboratoire de Physique de l'Ecole normale supérieure ENSUniversitéPSLCNRSSorbonne UniversitéUniversitéde Paris-CitéParisFrance School of Materials Science and Engineering Nanyang Technological UniversitySingaporeSingapore Laboratoire de Physique de la Matière Condensée Département de PhysiqueFacultédes Sciences de TunisUniversitéTunis El ManarCampus UniversitaireTunisTunisia Key Laboratory of Multifunctional Nanomaterials and Smart Systems Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhouJiangsuthe People's Republic of China IT4Innovations National Supercomputing CenterVSB—Technical University of OstravaOstrava-PorubaCzech Republic Faculty of Materials Science and Technology VSB—Technical University of OstravaOstrava-PorubaCzech Republic School of Electrical and Electronic Engineering&School of Physical and Mathematical Sciences The Photonics InstituteNanyang Technological UniversitySingaporeSingapore

Platinum diselenide(PtSe_(2))is a promising two-dimensional(2D)material for the terahertz(THz)range as,unlike other transition metal dichalcogenides(TMDs),its bandgap can be uniquely tuned from a semiconductor in the nearinfrared to a semimetal with the number of atomic *** gives the material unique THz photonic properties that can be ***,we demonstrate that a controlled THz nonlinearity—tuned from monolayer to bulk PtSe_(2)—can be realized in wafer size polycrystalline PtSe_(2)through the generation of ultrafast photocurrents and the engineering of the bandstructure *** is combined with the PtSe_(2)layer interaction with the substrate for a broken material centrosymmetry,permitting a second order ***,we show layer dependent circular dichroism,where the sign of the ultrafast currents and hence the phase of the emitted THz pulse can be controlled through the excitation of different bandstructure *** particular,we show that a semimetal has a strong dichroism that is absent in the monolayer and few layer semiconducting *** microscopic origins of this TMD bandstructure engineering are highlighted through detailed DFT simulations,and shows the circular dichroism can be controlled when PtSe_(2)becomes a semimetal and when the K-valleys can be *** well as showing that PtSe_(2)is a promising material for THz generation through layer controlled optical nonlinearities,this work opens up a new class of circular dichroism materials beyond the monolayer limit that has been the case of traditional TMDs,and impacting a range of domains from THz valleytronics,THz spintronics to harmonic generation.

关键词： 2D transition metal dichalcogenides Dirac semimetal optical nonlinearities terahertz valleytronics