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Influence of the Acoustic Liner in Large Eddy Simulation of Longitudinal Thermoacoustic Instability in a Model Annular Combustor

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journal of Thermal Science 2024年第2期33卷 710-724页

作者： MENG Sheng ZHANG man GAO Yi AECC Commercial Aircraft Engine Co. Ltd.Shanghai200241China School of Aeronautics and Astronautics Shanghai Jiao Tong UniversityShanghai200240China

Although extensive efforts have been made to dampen the thermoacoustic instability,successfully controlling the pressure oscillations in modern gas turbines or aeroengines remains *** influence of the acoustic liner on the longitudinal thermoacoustic mode in a model annular combustor is investigated by Large Eddy Simulation(LES) in this *** result of the self-excited longitudinal thermoacoustic instability without the liner agrees well with the frequency and acoustic analysis of the pressure mode based on experimental *** different bias flow velocities of the liner located downstream of the combustor are then *** results reveal that the existence of the liner influences not only the acoustic field but also the flow *** the bias velocity is large,it leads to intense turbulence-induced fluctuations,and the pressure oscillation is modulated *** shows that the weak coupling between flow and pressure oscillations plays a significant role in the onset of the intermittency of a thermoacoustic *** on the dynamic analysis of the thermoacoustic system with the acoustic liner,this intermittency is caused by the influence of the flow field on the flame-acoustic ***,a low-order modeling method based on Van der Pol(VdP) oscillator with additive stochastic forcing is conducted to reproduce the evolving dynamics of the thermoacoustic *** the numerical cases demonstrated in this work are relatively simpler than those in a practical combustion system,the results are helpful for us to understand the effect of the acoustic liner and show the attractive potential to apply this device to suppress thermoacoustic instability.

关键词： thermoacoustic instability acoustic liner Large Eddy Simulation low-order modeling

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Lactobacillus plantarum j26 alleviates alcohol-induced oxidative liver injury by regulating the Nrf2 signaling pathway

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Food Science and Human Wellness 2024年第4期13卷 2068-2078页

作者： Hongxuan Li Shasha Cheng Yuhong Wang Yilin Sun jiaxin Zhang Mingshuang Sun Chaoxin man Yu Zhang Yujun jiang Key Laboratory of Dairy Science Ministry of EducationCollege of Food Science and EngineeringNortheast Agricultural UniversityHarbin 150030China

Oxidative stress is one of the main ways to cause alcohol-induced liver injury,and alcoholic liver disease(ALD)has been a common health problem *** acid bacteria(LAB)is also considered as a potential treatment to alleviate alcohol-induced liver *** plantarum j26 is a LAB isolated from Chinese traditional fermented dairy products with excellent probiotic *** study aimed to establish a mice model of alcoholic liver injury through acute-on-chronic alcohol feeding and to study the alleviating effect of pre-intake of *** j26 on alcohol-induced oxidative liver injury and focus on its potential mechanism of alleviating *** results showed that pre-intake of *** j26 could improve liver pathological changes,reduce lipid accumulation,increase mitochondrial ATP and mitochondrial(mtDNA)levels,and alleviate liver *** addition,pre-intake *** j26 can improve the level of short-chain fatty acids(SCFAs)in the intestines in mice,short chain fatty acids can be used as a signaling molecule activation of nuclear factor E2-related factor 2(Nrf2)signaling pathway to alleviate liver oxidative stress,and maintain mitochondrial homeostasis by regulating the expression of genes related to mitochondrial dynamics and autophagy,thereby reducing cell apoptosis to alleviate alcohol-induced oxidative liver injury.

关键词： Alcoholic liver disease Probiotics Nuclear factor E2-related factor 2(Nrf2) Oxidative stress Short-chain fatty acids

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Large magnetocaloric effect and magnetic properties of EuRhO3

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journal of Rare Earths 2024年第9期42卷 1724-1729页

作者： M.Lassri M.Sajieddine A.elouafi A.el Hachmi S.el Ouahbi R.Moubah Laboratory of Energy and Materials Engineering (LGEM) University of Sultan Moulay SlimaneFaculty of Science and Technology (FST) Institute of Applied Physics (IAP)-School of Industrial management (EMINES) Mohammed Ⅵ Polytechnic University National School of Applied Sciences (ENSA) University of Sultan Moulay Slimane Laboratory of Mechanics Production and Industrial Engineering (LMPGI)Higher School of Technology of Casablanca (ESTC)University of Hassan Ⅱ Casablanca Laboratory of Radiation on Matter and Instrumentation (LRMI) Faculty of Science and Technology (FST) SettatHassan Ⅰ University Laboatory of Physics of Advanced Materials and Thermic (LPMAT) Faculty of Science Ain Chock (FSAC)University of Hassan Ⅱ Casablanca

We report on the structural,magnetic,and magnetocaloric properties of *** oxidation states of Eu and Rh ions were studied using X-ray photoelectron spectroscopy（XPS）.It is found that the Eu ions are mainly in the divalent oxidation state while the Rh ions have+4 ***3powders are found to be antiferromagnetic with a second order magnetic transition at Neel temperature（TN=2.9 K）.Analysis of the magnetic susceptibility versus temperature data in terms of the Curie=Weiss law:(χ=C/（T-θW）) for T>TN,yields θW=-3.1 K and effective magne tic moment ■,which is close to the theoretical value ■.The magnetic entropy change(-ΔSM),was determined by em ploying the thermodynam ic Maxwell's *** μ0H=5 T and near TN,■ and relative cooling power（RCP） exhibit large values of 33.7 j/（kg·K） and 238 j/kg,*** large magnitude of-ΔSmand RCP show that the EuRhO3compound could be a potential candidate to be used in cryogenic magnetic refrigeration.

关键词： Cryogenic magnetic refrigeration Magnetic properties Magnetocaloric effect Rare earths X-ray photoelectron spectroscopy

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Controllable nucleation and deformation of skyrmions on surface of magnetic nanotubular monolayer

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Rare Metals 2024年第7期43卷 3250-3259页

作者： Xin-Xin Zhang Chen-Yu Zhang Yi-Xin Xing Chao man jiao Liu Yong Hu Department of Physics College of SciencesNortheastern UniversityShenyang 110819China School of Materials and Mineral Resources Engineering Universiti Sains MalaysiaEngineering Campus14300 Nibong TebalPenangMalaysia State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819China

Magnetic skyrmions emerge when the energy of ferromagnetic exchange interaction promoting parallel alignment of spins enters in competition with energies favoring non-collinear alignment of spins such as Dzy aloshinskii-Moriya interaction(DMI),long-rang dipole-dipole interaction(DDI),or higher-order exchange *** perform an unbiased Monte Carlo simulation to study the DMI-based skyrmion nucleation and stabilization on the surface of magnetic nanotubular monolayer controlled by tuning constants of DDI(g) and next-nearest-neighbor antiferromagnetic exchange interaction(j') with appropriate *** g and j',the loosely distributed skyrmions initially nucleate on the surface of nanotube approaching to the magnetic field(h) direction with increasing h in the intermediate ***,the skyrmion size,shape,density,distribution and crystal structure,as well as its driven field range,are tailored by g and j'.This work demonstrates the skyrmion nucleation mechanisms in three-dimensional magnetic nanostructures with curvature effect and multiple interactions,serving as a benchmark for a guide to experimentalists for preparation of samples in magnetic skyrmion states.

关键词： Magnetic nanotube Magnetic skyrmion Dzyaloshinskii-Moriya interaction Dipole-dipole interaction Monte Carlo simulation

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Albumin–bilirubin grade as a predictor of survival in hepatocellular carcinoma patients with thrombocytopenia

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World journal of Gastrointestinal Oncology 2024年第5期16卷 1763-1772页

作者： Zhong-Ran man Xuan-Kun Gong Kang-Lin Qu Qing Pang Bin-Quan Wu Department of Hepatobiliary Surgery The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina Department of Hepatobiliary Surgery Anhui No.2 Provincial People’s HospitalHefei 230041Anhui ProvinceChina

BACKGROUND The models for assessing liver function,mainly the Child–Pugh(CP),albuminbilirubin(ALBI),and platelet–ALBI(PALBI)classifications,have been validated for use in estimating the prognosis of hepatocellular carcinoma(HCC)***,thrombocytopenia is a common finding and may influence the prognostic value of the three models in *** To investigate and compare the prognostic performance of the above three models in thrombocytopenic HCC *** A total of 135 patients with thrombocytopenic HCC who underwent radical surgery were retrospectively *** scores on the CP,ALBI and PALBI classifications were estimated ***–Meier curves with logrank tests and Cox regression models were used to explore the significant factors associated with overall survival(OS)and recurrence-free survival(RFS).RESULTS The preoperative platelet counts were significantly different among the CP,ALBI and PALBI *** a median follow-up of 28 mo,39.3%(53/135)of the patients experienced postoperative recurrence,and 36.3%(49/135)*** analysis suggested thatα-fetoprotein levels,tumor size,vascular invasion,and ALBI grade were significant predictors of OS and *** to the multivariate Cox regression model,ALBI was identified as an independent prognostic ***,CP and PALBI grades were not statistically significant prognostic *** The ALBI grade,rather than CP or PALBI grade,is a significant prognostic indicator for thrombocytopenic HCC patients.

关键词： Hepatocellular carcinoma Thrombocytopenia Child-Pugh Albumin-bilirubin Platelet-albumin-bilirubin

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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors

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Signal Transduction and Targeted Therapy 2024年第2期9卷 679-692页

作者： Keith Al-Hasani Safiya Naina Marikar Harikrishnan Kaipananickal Scott Maxwell jun Okabe Ishant Khurana Thomas Karagiannis julia j.Liang Lina Mariana Thomas Loudovaris Thomas Kay Assam el-Osta Epigenetics in Human Health and Disease Program Baker Heart and Diabetes Institute75 Commercial RoadMelbourne 3004 VICAustralia Department of Diabetes Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia Epigenetics in Human Health and Disease Laboratory Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia School of Science STEM CollegeRMIT UniversityMelbourne 3001 VICAustralia Immunology and Diabetes Unit St Vincent’s Institute of Medical ResearchFitzroy 3065 VICAustralia Department of Medicine and Therapeutics The Chinese University of Hong KongSha TinHong Kong SAR Hong Kong Institute of Diabetes and Obesity Prince of Wales HospitalThe Chinese University of Hong Kong3/F Lui Che Woo Clinical Sciences Building30-32-Ngan Shing StreetSha TinHong Kong SAR Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongSha TinHong Kong SAR Biomedical Laboratory Science Department of TechnologyFaculty of HealthUniversity College CopenhagenCopenhagenDenmark

β-cells are a type of endocrine cell found in pancreatic islets that synthesize,store and release *** type 1 diabetes(T1D),T-cells of the immune system selectively destroy the insulin-producingβ-*** of these cells leads to a lifelong dependence on exogenous insulin administration for ***,there is an urgent need to identify novel therapies that stimulateβ-cell growth and induceβ-cell *** and others have shown that pancreatic ductal progenitor cells are a promising source for regeneratingβ-cells for T1D owing to their inherent differentiation *** transcriptional suppression is refractory to exocrine reaction and tightly controls the regenerative potential by the EZH2 *** the present study,we show that transient stimulation of exocrine cells,derived from juvenile and adult T1D donors to the FDAapproved EZH2 inhibitors GSK126 and Tazemetostat(Taz)influence a phenotypic shift towards aβ-like cell *** transition from repressed to permissive chromatin states are dependent on bivalent H3K27me3 and H3K4me3 chromatin *** EZH2 is fundamental toβ-cell regenerative *** pancreatic ductal cells exhibit insulin production and secretion in response to a physiological glucose challenge ex *** pre-clinical studies underscore the potential of small molecule inhibitors as novel modulators of ductal progenitor differentiation and a promising new approach for the restoration ofβ-like cell function.

关键词： EZH2 struction inhibitors

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Toward understanding the microstructure characteristics,phase selection and magnetic properties of laser additive manufactured Nd-Fe-B permanent magnets

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International journal of Extreme manufacturing 2024年第1期6卷 277-294页

作者： Bo Yao Nan Kang Xiangyu Li Dou Li Mohamed el mansori jing Chen Haiou Yang Hua Tan Xin Lin State Key Laboratory of Solidiffcation Processing Northwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Arts et Metiers Institute of Technology MSMPHESAM UniversitéF-51006 Chˆalons-en-ChampagneFrance Key Laboratory of Metal High Performance Additive manufacturing and Innovative Design MIIT ChinaNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Texas A&M Engineering Experiment Station Institute for Manufacturing SystemsCollege StationTX 77843United States of America

Nd-Fe-B permanent magnets play a crucial role in energy conversion and electronic *** essential magnetic properties of Nd-Fe-B magnets,particularly coercivity and remanent magnetization,are significantly infuenced by the phase characteristics and *** this work,Nd-Fe-B magnets were manufactured using vacuum induction melting(VIM),laser directed energy deposition(LDED)and laser powder bed fusion(LPBF)*** evolution and phase selection of Nd-Fe-B magnets were then clarified in *** results indicated that the solidification velocity(V)and cooling rate(R)are key factors in the phase *** terms of the VIM-casting Nd-Fe-B magnet,a large volume fraction of theα-Fe soft magnetic phase(39.7 vol.%)and Nd2Fe17Bxmetastable phase(34.7 vol.%)areformed due to the low R(2.3×10-1?C s-1),whereas only a minor fraction of the Nd2Fe14B hard magnetic phase(5.15 vol.%)is *** the LDED-processed Nd-Fe-B deposit,although the Nd2Fe14B hard magnetic phase also had a low value(3.4 vol.%)as the values of V(10-2m s-1)and R(1.45×106?C s-1)in the LPBF process resulted in the substantial formation of the Nd2Fe14B hard magnetic phase(55.8 vol.%)directly from the liquid,while theα-Fe soft magnetic phase and Nd2Fe17Bxmetastable phase precipitation are suppressed in the LPBF-processed Nd-Fe-B ***,crystallographic texture analysis reveals that the LPBF-processedNd-Fe-B magnets exhibit isotropic magnetic ***,the LPBF-processed Nd-Fe-B deposit,exhibiting a coercivity of 656 k A m-1,remanence of 0.79 T and maximum energy product of 71.5 k j m-3,achieved an acceptable magnetic perfor

关键词： laser additive manufacturing(LAM) Nd-Fe-B permanent magnets numerical simulation microstructure magnetic properties

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Error field penetration in j-TEXT tokamak based on two-fluid drift-MHD model

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Chinese Physics B 2024年第4期33卷 545-551页

作者：王文徐涛张仪 the j-TEXT team State Key Laboratory of Advanced electromagnetic Technology International Joint Research Laboratory of Magnetic Confinement Fusion and Plasma PhysicsSchool of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China

An externally generated resonant magnetic perturbation can induce complex non-ideal MHD responses in their resonant *** have studied the plasma responses using Fitzpatrick's improved two-fluid model and program *** calculated the error field penetration threshold for *** addition,we find that the island width increases slightly as the error field amplitude increases when the error field amplitude is below the critical penetration ***,the island width suddenly jumps to a large value because the shielding effect of the plasma against the error field disappears after the *** scanning the natural mode frequency,we find that the shielding effect of the plasma decreases as the natural mode frequency ***,we obtain the m/n=2/1 penetration threshold scaling on density and temperature.

关键词： plasma responses drift-MHD model error field penetration

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Large magnetocaloric effect and magnetic properties of EuRhO_(3)

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journal of Rare Earths 2024年第9期42卷 1724-1729,I0004页

作者： M.Lassri M.Sajieddine A.elouafi A.el Hachmi S.el Ouahbi R.Moubah Laboratory of Energy and Materials Engineering(LGEM) University of Sultan Moulay SlimaneFaculty of Science and Technology(FST)BP 52323000Béni-MellalMorocco Institute of Applied Physics(IAP)-School of Industrial management(EMINES) Mohammed Ⅵ Polytechnic UniversityHay Moulay RachidLot 6603150Ben GuerirMorocco National School of Applied Sciences(ENSA) University of Sultan Moulay SlimaneBP 7725000KhouribgaMorocco Laboratory of Mechanics Production and Industrial Engineering(LMPGI)Higher School of Technology of Casablanca(ESTC)University of Hassan Ⅱ CasablancaCasablancaMorocco Laboratory of Radiation on Matter and Instrumentation(LRMI) Faculty of Science and Technology(FST)SettatHassan Ⅰ UniversitySettatMorocco Laboatory of Physics of Advanced Materials and Thermic(LPMAT) Faculty of Science Ain Chock(FSAC)University of Hassan Ⅱ CasablancaCasablancaMorocco

We report on the structural,magnetic,and magnetocaloric properties of EuRhO_(3) *** oxidation states of Eu and Rh ions were studied using X-ray photoelectron spectroscopy(XPS).It is found that the Eu ions are mainly in the divalent oxidation state while the Rh ions have+4 ***_(3) powders are found to be antiferromagnetic with a second order magnetic transition at Neel temperature(T_(N)=2.9 K).Analysis of the magnetic susceptibility versus temperature data in terms of the Curie=Weiss law:(χ=C/(T-θ_(W))) for T>T_(N),yields θ_(W)=-3.1 K and effective magne tic moment μ_(ff)^(exp),which is close to the theoretical value μ_(eff)^(theo).The magnetic entropy change(-Δ_(SM)),was determined by em ploying the thermodynam ic Maxwell's *** μ_0H=5 T and near T_(N),ΔS_(M)^(Max) and relative cooling power(RCP) exhibit large values of 33.7 j/(kg·K) and 238 j/kg,*** large magnitude of-Δ_(SM) and RCP show that the EuRhO_(3) compound could be a potential candidate to be used in cryogenic magnetic refrigeration.

关键词： X-ray photoelectron spectroscopy Cryogenic magnetic refrigeration Magnetic properties Magnetocaloric effect Rare earths

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Factors affecting meibomian gland area loss in symptomatic adults

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International journal of Ophthalmology(English edition) 2024年第6期17卷 1036-1041页

作者： Si-Cheng Ding jing-jing Su Qing Zhan jiao-man Wang Fang Zheng Xu-Xuan Fang Dan Cheng Ping Guo The Second Clinical Medical College Jinan UniversityShenzhen 518000Guangdong ProvinceChina Shenzhen Eye Hospital Jinan UniversityShenzhen Eye InstituteShenzhen 518040Guangdong ProvinceChina Department of Ophthalmology Jinzhou Medical UniversityJinzhou 121000Liaoning ProvinceChina

AIM:To characterize the distribution of meibomian gland(MG)area loss(MGL)and its relationship with demographic characteristics,mites,and ***:This retrospective observational study included patients who visited the Dry Eye Clinic of Shenzhen Eye Hospital between june 2020 and August *** patient characteristics,ocular symptoms,Demodex test results of the eyelid edges,and the results of a comprehensive ocular surface analysis were *** was analyzed using Image j ***:This study enrolled 1204 outpatients aged 20-80(40.70±13.44)y,including 357 males(29.65%)and 847 females(70.35%).The patients were classified into mild(n=155;12.87%),moderate(n=795;66.03%),severe(n=206;17.11%),and extremely severe(n=48;3.99%)MGL *** was significantly larger in female than in male(P=0.006).The degree of MGL also significantly differed in age(Pely to be older,female,more numbers of mites,and increased secretion.

关键词： meibomianglands aging sex symptomatology Demodex

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