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Chinese Chemical Letters 2009年第11期20卷 1389-1392页

作者： G.Rezaei Behbehani A.A.Saboury m.mohebbian S.Tahmasbi Sarvestani m.Poorheravi Chemistry Department Imam Khomeini International UniversityQazvinIran Institute of Biochemistry and Biophysics University of TehranTehranIran Chemistry Department Payame Noor University(PNU)AbharIran

Cyanide ion was studied as an inhibitor of jack bean urease at 300 K in 30 mmol/L tris buffer, pH 7. The inhibition was investigated by isothermal titration calorimetry （ITC）. The extended solvation model was used for CN^- ＋ jBU interaction over the whole range of CN^- concentrations. The binding parameters recovered from the solvation model were attributed to the cyanide ion interaction. It was found that cyanide ion acted as a non-cooperative inhibitor ofurease, and there is a set of 12 ± 0.12 identical and independent binding sites for CN- ions. The dissociation equilibrium constant is 749.99 umol/L. The molar enthalpy of binding is AH= -13.60 kj mol^-1.

关键词： jack bean urease Cyanide ion Isothermal titration calorimetry Binding parameters Inhibitor

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Pharmacological methods for ovarian function and fertility preservation in women with cancer:A literature review

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Oncology Research 2024年第8期32卷 1309-1322页

作者： ANA S.CVETANOVIC mATTEO LAmBERTINI KEVIN PUNIE GORANA G.mATOVINA BRKO NIKOLA D.ZIVKOVIC mAjA j.POPOVIC mARIjANA m.mILOVIC KOVACEVIC LAZAR S.POPOVIC Department for Oncology Medical Faculty NisUniversity of NisNis18000Serbia Clinic of Oncology University Clinical Centre NisNis18000Serbia Department of Internal medicine and medical Sciences(DimI) School of MedicineUniversity of GenovaGenova16100Italy Department of medical Oncology U.O.C Clinica di Oncologia MedicaIRCCS Ospedale Policlinico San MartinoGenova16100Italy Department of General medical Oncology and multidisciplinary Breast Centre Leuven Cancer InstituteUniversity Hospitals LeuvenLeuven3001Belgium Department of medical Oncology Oncology Institute of VojvodinaSremska Kamenica21208Serbia Department for Pathology Medical Faculty NisUniversity of NisNis18000Serbia Center for Pathology University Clinical Centre NisNis18000Serbia Faculty of medicine University of Novi SadNovi Sad21000Serbia Department of medical Oncology Institute of Oncology and Radiology SerbiaBelgrade11000Serbia

Oncofertility is an extremely signiﬁcant topic that is increasingly being discussed owing to increased evidence indicating that fertility preservation does not affect the treatment outcomes of patients with cancer but signiﬁcantly contributes to preserving life *** effect of chemotherapy can range from minimal effects to complete ovarian *** data are available on the effects of monoclonal antibodies and targeted therapies on the ovaries and *** ovarian suppression by administering a gonadotropin-releasing hormone agonist(GnRHa)during chemotherapy decreases the gonadotoxic effect of chemotherapy,thereby diminishing the chance of developing premature ovarian insufﬁciency(POI).At present,the concomitant administration of GnRH analogs during chemotherapy is the only accepted pharmacological method for preserving ovarian ***,most randomized studies on the effectiveness of luteinizing hormone-releasing hormone agonists during chemotherapy in preventing POI have been conducted in women with breast cancer,with a considerably small number of studies on patients with hematological ***,most randomized controlled trials on breast cancer have revealed a decrease in treatment-induced POI risk,regardless of the hormone receptor *** addition,studies on hematological malignancies have yielded negative results;nevertheless,theﬁndings must be interpreted with caution owing to numerous *** guidelines from the American Society of Clinical Oncology and ESmO Clinical Practice Guidelines recommend sperm,oocyte,and embryo cryopreservation as a standard practice and only offering GnRHa to patients when proven fertility preservation methods are not *** this manuscript,we present a comprehensive literature overview on the application of ovarian suppression with GnRHa during chemotherapy in patients with cancer by addressing preclinical and clinical data,as well as future perspectives in thisﬁeld

关键词： Gonadotropin-releasing hormone agonists(GnRHa) Fertility preservation Premature ovarian insufficiency(POI) Premenopausal patients

Control Alternatives for Damping-Off in Tomato Seedling Production

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Phyton-International journal of Experimental Botany 2019年第3期88卷 325-333页

作者： A.C.michel-Aceves j.F.Díaz-Nájera R.Ariza-Flores m.A.Otero-Sánchez R.Escobar-martínez C.H.Avendaño-Arrazate Centro de Estudios Profesionales del Colegio Superior Agropecuario del Estado de Guerrero Av.Vicente Guerrero No.81Colonia CentroIgualaGuerreroC.P.40000México Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias(INIFAP)Campo Experimental IgualaCarr.Iguala-TuxpanKm.2.5 IgualaGuerreroMéxico INIFAP-Campo Experimental Rosario Izapa.Carr.Tapachula-Cacahoatán Tuxtla chicoChiapasC.P.30870México

In two tomato genotypes,we assessed control alternatives for damping-off with combinations of chemical fungicides and native/commercial strains of biological *** treatments consisting of 19 levels of mixing products,chemical fungicides,native strains and commercial products from biological control agents,and untreated treatment were used onto Ramsés and Toro *** were distributed on an incomplete block design in divided plots arrangement,where genotypes constitute the larger ones and the 8-repetition mixed products,the smaller *** 180 mL of fungal complexes,made of spores and mycellium Fusarium-solani(2×106 UFC),Rhizoctonia-solani(1×106 UFC),Phytophthora-capsici(1×105 UFC)and Sclerotium-rolfsii(mycellium-sclerotia)on each seedling trays,made inoculation *** mixtures of(Bacillus spp.+Streptomyces spp.+Trichoderma spp.)+(Propamocarb+Fosetyl);(Bacillus spp.+Streptomyces spp.+Trichoderma spp.)+(metalaxyl+Chlorothalonil);Pseudomonas fluorescens+Streptomyces+micromonospore+Sporideamium+Aminoacidos,Péptidos,Carbohidratos)+(Propamocarb+Fosetyl);the native strain of Trichoderma asperellum+(Propamocarb+fosetil)and the native strains Trichoderma asperellum+Bacillus subtilis,diminished damping-off,prevented its appearance and had most significant agronomic *** contrast to this,combination of(mancozeb)+(Free iodine)+(metalaxyl+Chlorothalonil)+(methyl thiophanate)produced some toxicity in the *** addition,Ramsés presented the best agronomic parameters,while Toro had the utmost fresh and dry weight in root.

关键词： Trichoderma harzianum T.lignorum biological control

Data-driven prediction of temperature variations in an open cathode proton exchange membrane fuel cell stack using Koopman operator

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Energy and AI 2023年第4期14卷 439-450页

作者： Da Huo Carrie m.Hall mechanical Materialsand Aerospace Engineering DepartmentIllinois Institute of Technology10 West 35th StreetChicago60616ILUnited States

In this study,a novel application of the Koopman operator for control-oriented modeling of proton exchange membrane fuel cell(PEmFC)stacks is *** primary contributions of this paper are:(1)the design of Koopman-based models for a fuel cell stack,incorporating K-fold cross-validation,varying lifted dimensions,radial basis functions(RBFs),and prediction horizons;and(2)comparison of the performance of Koopman-based approach with a more traditional physics-based *** results demonstrate the high accuracy of the Koopman-based model in predicting fuel cell stack behavior,with an error of less than 3%.The proposed approach offers several advantages,including enhanced computational efficiency,reduced computational burden,and improved *** study demonstrates the suitability of the Koopman operator for the modeling and control of PEmFCs and provides valuable insights into a novel control-oriented modeling approach that enables accurate and efficient predictions for fuel cell stacks.

关键词： Proton exchange membrane fuel cell(PEmFC) Data-driven modeling Koopman operator Dynamic modeling Control-oriented modeling Physics-based modeling

Estimating the prevalence of Echinococcus in domestic dogs in highly endemic for echinococcosis

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Infectious Diseases of Poverty 2018年第1期7卷 761-769页

作者： Cong-Nuan Liu Yang-Yang Xu Angela m.Cadavid-Restrepo Zhong-Zi Lou Hong-Bin Yan Li Li Bao-Quan Fu Darren j.Gray Archie A.Clements Tamsin S.Barnes Gail m.Williams Wan-Zhong jia Donald P.mcmanus Yu-Rong Yang State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Veterinary Parasitology of Gansu Province/Key Laboratory of Zoonoses of Agriculture ministry/Lanzhou Veterinary Research Institute CAASLanzhou 730046People’s Republic of China The Human Pathology and Immunology Department Ningxia Medical UniversityYinchuanNingxia Hui Autonomous RegionPeople’s Republic of China Neurosurgery Department Tianjin Xiqing HospitalTianjinPeople’s Republic of China molecular Parasitology Laboratory QIMR Berghofer Medical Research InstituteBrisbaneAustralia Research School of Population Health Australian National UniversityCanberraAustralia School of Population Health Infectious Disease Epidemiology UnitUniversity of QueenslandBrisbaneAustralia Queensland Alliance for Agriculture and Food Innovation University of QueenslandGattonAustralia

Background:Cystic echinococcosis(CE)and alveolar echinococcosis(AE)are highly endemic in Xiji County of Ningxia Hui Autonomous Region(NHAR)in China where the control campaign based on dog de-worming with praziquantel has been undertaken over preceding *** study is to determine the current prevalence of Echinococcus granulosus and *** in domestic dogs and monitor the echinococcosis transmission ***:Study villages were selected using landscape patterns(Geographic Information System,GIS)for Echinococcus transmission“hot spots”,combined with hospital records identifying risk areas for AE and CE.A survey of 750 domestic dogs,including copro-sampling and owner questionnaires,from 25 selected villages,was undertaken in 2012.A copro-multiplex PCR assay was used for the specific diagnosis of *** and *** in the *** analysis,using IBm SPSS Statistics,was undertaken,to compare the prevalence of the two Echinococcus *** dogs between four geographical areas of Xiji by theχ^(2)*** analysis of the combinations of outcomes from the questionnaire and copro-PCR assay data was carried out to determine the significant risk factors for dog ***:The highest de-worming rate of 84.0%was found in the northwest area of Xiji County,and significant differences(Pming rates among dogs from the four geographical areas of Xiji were *** highest prevalence(19.7%,59/300)of *** occurred in northwest Xiji,though the highest prevalence(18.1%,38/210)of *** occurred in southwest *** was no significant difference(P>0.05)in the prevalence of *** in dogs from the northwest,southwest,northeast,and southeast of Xiji,but there were significant differences(Pm the four *** of the other independent variables was statistically ***:The results from this study indicate a high prevalenc

关键词： Domestic dog surveys Dog-copro-multiplex PCR assay Co-endemicity of Echinococcus granulosus and E.multilocularis Xiji County Ningxia hui autonomous region(NHAR) P.R.China

movement Disorder Emergencies: Diagnosis and Treatment 2

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晚震旦世—寒武纪沟鞭藻存在的生物和分子地球化学证据

丛书名： Current Clinical Neurology

2013年

作者： Steven j. Frucht m.D. (auth.), Steven j. Frucht (eds.)

来源：畅想之星图书光盘版（南... 评论

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地质学报 2000年第4期 378-379页

作者：张水昌,j.m.moldowan,边立曾,张宝民,F.j.Fago CA9435 USA 北京 100083 210093 北京 100083 石油勘探开发科学研究院 Department of Geological and Environmental Sciences Stanford University CA94305 USA 南京大学地球科学系石油勘探开发科学研究院 Department of Geological and Environmental Sciences Stanford University

沟鞭藻是反映现代海洋和湖泊生态条件的单细胞生物,其最早的无可争议的化石纪录是从中三叠世(约240ma前)开始。最近,moldowan等(1996)在对不同地质时代海相岩石的调查中,发现在前寒武纪至泥盆纪富有机质的沉积岩石中具有丰富的三芳甲藻... 详细信息

沟鞭藻是反映现代海洋和湖泊生态条件的单细胞生物,其最早的无可争议的化石纪录是从中三叠世(约240ma前)开始。最近,moldowan等(1996)在对不同地质时代海相岩石的调查中,发现在前寒武纪至泥盆纪富有机质的沉积岩石中具有丰富的三芳甲藻甾烷。Summons等(1992)也注意到甲藻甾烷出现在前寒武纪岩石抽提有机质中。而作为甲藻甾类烃(甲藻甾烷和三芳甲藻甾烷)的生物化学先质的甲藻甾醇是唯一由沟鞭藻衍生的(Volkman等,1990;1998)。这种甲藻甾烷与沟鞭藻之间的亲缘关系几乎可将其作为证明沟鞭藻存在的生物分子化石。moldowan和Talyzina(1998)在一些已知形态特征的经过富集了的早寒武世(约520ma以前)微化石中鉴定出了一系列沟鞭藻生源的生物标志物(甲藻甾烷和4α-甲基-24-乙基胆甾烷),并认为这些微化石是古老的沟鞭藻祖先。

关键词：沟鞭藻甲藻微化石前寒武纪前古生代抽提物

Forced vibration analysis of nano-composite rotating pressurized microbeam reinforced by CNTs based on mCST with temperature-variable material properties

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Theoretical & Applied mechanics Letters 2018年第2期8卷 97-108页

作者： R.Rostami m.mohammadimehr m.Ghannad A.jalali Department of Solid mechanics Faculty of Mechanical EngineeringShahrood University of Technology Department of Solid mechanics Faculty of Mechanical EngineeringUniversity of Kashan

In this study, free and forced vibration analysis of nano-composite rotating pressurized microbeam reinforced by carbon nanotubes （CNTs） under magnetic field based on modify couple stress theory （mCST） with temperature-variable material propertiesis presented. Also, the boundary conditions at two ends of nano-composite rotating pressurized microbeam reinforced by CNTs are considered as simply supported. The governing equations are obtained based on the Hamilton＇s principle and then computed these equations by using Navier＇s solution. The magnetic field is inserted in the thickness direction of the nano-composite microbeam. The effects of various parameters such as angular velocity, temperature changes, and pressure between of the inside and outside, the magnetic field, material length scale parameter, and volume fraction of nanocomposite microbeam on the natural frequency and response systemare studied. The results show that with increasing volume fraction of nano-composite microbeam, thickness, material length scale parameter, and magnetic fields, the natural frequency increases. The results of this research can be used for optimization of micro-structures and manufacturing sensors, displacement fluid, and drug delivery.

关键词： Forced vibration analysis Nano-composite rotating pressurized microbeam Carbon nanotubes modify couple stress theory Temperature-variable material properties

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心理测验在中国临床心理学中的应用以及与美国资料的比较

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中国临床心理学杂志 1993年第1期1卷 47-50,64+21页

作者：戴晓阳郑立新 j.j.Ryan A.m.Paolo 湖南医科大学湖南省儿童医院美国堪萨斯州艾森豪威尔退伍军人医学中心

本研究对国内315个心理测验使用单位进行了调查,共收到有效回复183份(回复率58.1％)。调查结果表明:1979年—1989年间所调查的单位平均已使用测验5.1年(标准差2.85);使用的主要目的是辅助诊断、科研和心理治疗与咨询;至1989年底,已在我... 详细信息

本研究对国内315个心理测验使用单位进行了调查,共收到有效回复183份(回复率58.1％)。调查结果表明:1979年—1989年间所调查的单位平均已使用测验5.1年(标准差2.85);使用的主要目的是辅助诊断、科研和心理治疗与咨询;至1989年底,已在我国临床心理学中应用的测验达80多种,在最常用的37种心理测验中,使用频度最高的是智力测验和非投射人格测验。与美国1982年的同类调查相比较,投射测验在我国少有人应用,而精神疾病评定量表的使用频度则很高。作者还指出提高测验使用者的专业水平是我国临床心理学界的一个重要课题。

关键词：临床心理学心理测验

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