检索结果-南通市图书馆

Reduction of epinephrine in the lumbar spinal cord following repetitive blast-induced traumatic brain injury in rats

引用

Neural Regeneration Research 2024年第7期19卷 1548-1552页

作者： Shigeharu Tsuda Mustafa Golam jiamei Hou Kevin K.W.Wang Floyd j.Thompson Prodip bose Brain Rehabilitation Research Center Malcom Randall VA Medical CenterNorth Florida/South Georgia Veterans Health SystemGainesvilleFLUSA Department of Anesthesiology College of MedicineUniversity of FloridaGainesvilleFLUSA Department of Emergency Medicine University of FloridaGainesvilleFLUSA Department of Neuroscience University of FloridaGainesvilleFLUSA Department of Neurology University of FloridaGainesvilleFLUSA

Traumatic brain inju ry-induced unfavorable outcomes in human patients have independently been associated with dysregulated levels of monoamines,especially epinephrine,although few preclinical studies have examined the epinephrine level in the central nervous system after traumatic brain *** has been shown to regulate the activities of spinal motoneurons as well as increase the heart rate,blood pressure,and blood flow to the hindlimb ***,the purpose of the present study was to determine the impact of repeated blast-induced traumatic brain injury on the epinephrine levels in seve ral function-s pecific central nervous system regions in *** three repeated blast injuries at 3-day intervals,the hippocampus,motor cortex,locus coeruleus,vestibular nuclei,and lumbar spinal cord were harvested at post-injury day eight and processed for epinephrine assays using a high-sensitive electrochemical detector cou pled with high-performance liquid *** results showed that the epinephrine levels were significantly decreased in the lumbar spinal cord tissues of blast-induced traumatic brain injury animals compared to the levels detected in age-and sex-matched sham *** other function-specific central nervous system regions,although the epinephrine levels were slightly altered following blast-induced tra u matic brain injury,they were not statistically *** results suggest that blast injury-induced significant downregulation of epinephrine in the lumbar spinal cord could negatively impact the motor and cardiovascular *** is the first repo rt to show altered epinephrine levels in the spinal cord following repetitive mild blast-induced traumatic brain injury.

关键词： balance blood flow cardiovascular system central nervous system epinephrine ischemic damage lumbar spinal cord muscle tone repeated blast spasticity traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Anneal-free ultra-low loss silicon nitride integrated photonics

引用

Light(Science & Applications) 2024年第8期13卷 1565-1577页

作者： Debapam bose Mark W.Harrington Andrei Isichenko Kaikai Liu jiawei Wang Nitesh Chauhan Zachary L.Newman Daniel j.Blumenthal Department of Electrical and Computer Engineering University of California Santa BarbaraSanta BarbaraCA 93106USA Octave Photonics LouisvilleCO 80027USA

Heterogeneous and monolithic integration of the versatile low-loss silicon nitride platform with low-temperature materials such as silicon electronics and photonics,III–V compound semiconductors,lithium niobate,organics,and glasses has been inhibited by the need for high-temperature annealing as well as the need for different process flows for thin and thick *** techniques are needed to maintain the state-of-the-art losses,nonlinear properties,and CMOS-compatible processes while enabling this next generation of 3D silicon nitride *** report a significant advance in silicon nitride integrated photonics,demonstrating the lowest losses to date for an anneal-free process at a maximum temperature 250℃,with the same deuterated silane based fabrication flow,for nitride and oxide,for an order of magnitude range in nitride thickness without requiring stress mitigation or *** report record low anneal-free losses for both nitride core and oxide cladding,enabling 1.77 dBm-1 loss and 14.9 million Q for 80 nm nitride core waveguides,more than half an order magnitude lower loss than previously reported sub 300℃ *** 800 nm-thick nitride,we achieve as good as 8.66 dBm-1 loss and 4.03 million Q,the highest reported Q for a low temperature processed resonator with equivalent device area,with a median of loss and Q of 13.9 dBm-1 and 2.59 million each *** demonstrate laser stabilization with over 4 orders of magnitude frequency noise reduction using a thin nitride reference cavity,and using a thick nitride micro-resonator we demonstrate OPO,over two octave supercontinuum generation,and four-wave mixing and parametric gain with the lowest reported optical parametric oscillation threshold per unit resonator *** results represent a significant step towards a uniform ultra-low loss silicon nitride homogeneous and heterogeneous platform for both thin and thick waveguides capable of linear and nonlinear photonic circuits and integrat

关键词： resonator thick free

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

脾钝性损伤:多层螺旋CT脾损伤分级系统及临床参数在病人入院分拣时的应用

引用

国际医学放射学杂志 2015年第3期 268-268页

作者： N.Saksobhavivat K.Shanmuganathan H.H.Chen j.j.du bose H.Richard M.A.Khan 柯勤兵 Department of Diagnostic Radiology and Nuclear Medicine University of Maryland School of Medicine22 S Greene StBaltimore MD 21201

目的评估单独应用多层螺旋CT双期扫描脾损伤分级系统以及与临床参数相结合在脾钝性损伤病人分拣决定合适的治疗方案[保守观察、脾动脉栓塞术(SAE)或脾切除

关键词：脾损伤分级分级系统病人最佳控制系统临床参数螺旋 CT

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Revealing excited states of rotational bose-Einstein condensates

引用

The Innovation 2024年第1期5卷 41-48页

作者： jianyuan Yin Zhen Huang Yongyong Cai Qiang du Lei Zhang School of Mathematical Sciences Laboratory of Mathematics and Applied MathematicsPeking UniversityBeijing 100871China Department of Mathematics National University of SingaporeSingapore 119076Singapore Department of Mathematics University of CaliforniaBerkeleyBerkeleyCA 94720USA School of Mathematical Sciences Beijing Normal UniversityBeijing 100875China Department of Applied Physics and Applied Mathematics and Data Science Institute Columbia UniversityNew YorkNY 10027USA Beijing International Center for Mathematical Research Center for Quantitative BiologyCenter for Machine Learning ResearchPeking UniversityBeijing 100871China

Rotational bose-Einstein condensates can exhibit quantized vortices as topological *** this study,the ground and excited states of the rotational bose-Einstein condensates are systematically studied by calculating the stationary points of the Gross-Pitaevskii energy *** excited states and their connections at different rotational frequencies are revealed in solution landscapes constructed with the constrained high-index saddle dynamics *** excitation mechanisms are identified:vortex addition,rearrangement,merging,and *** demonstrate changes in the ground state with increasing rotational frequencies and decipher the evolution of the stability of ground states.

关键词： method rotational excited

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

L_1 regression estimate and its bootstrap

引用

Science China Mathematics 2009年第6期52卷 1251-1261页

作者： bose Arup Statistics and Mathematics Unit Indian Statistical Institute203 B.T.RoadKolkata 700108India

We study the asymptotic distribution of the L1 regression estimator under general condi-tions with matrix norming and possibly non *** then introduce an appropriate bootstrap procedure to estimate the distribution of this estimator and study its asymptotic *** is shown that this bootstrap is consistent under suitable conditions and in other situations the bootstrap limit is a random distribution.

关键词： L_1 regression matrix norming central limit theorem asymptotic distribution gen-eralized bootstrap

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

New two chamber transfer switch for 6500 A commutation current

引用

Global Energy Interconnection 2018年第3期1卷 344-351页

作者： Lutz-Rüdiger jänicke jörg Teichmann Shibani bose Weidong Han Xiaoming Wang Siemens AG Siemens Ltd.China Siemens High voltage Circuit Breaker Co. Ltd.

HVDC transfer switches are used in different locations in electrode lines of HVDC transmission systems for their reconfigurations. They have to carry and commutate currents to the overload currents of HVDC transmission systems, which increased to 6,400 A in the past years. Common designs of transfer switches use combinations of several switching units connected in series and parallel. This paper describes the design and development of a new DC commutation switch with two switching units only, but it is able to carry currents up to 10,000 A and has an actual tested commutation capability of 6,500 A.

关键词： HVDC Switch Passive resonance 6,500 A commutation current 10,000 A nominal current

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mild closed head traumatic brain injury-induced changes in monoamine neurotransmitters in the trigeminal subnuclei of a rat model:mechanisms underlying orofacial allodynias and headache

引用

Neural Regeneration Research 2017年第6期12卷 981-986页

作者： Golam Mustafa jiamei Hou Rachel Nelson Shigeharu Tsuda Mansura jahan Naweed S.Mohammad joseph V.Watts Floyd j.Thompson Prodip bose Brain Rehabilitation Research Center of Excellence Malcom Randall VA Medical Center North Florida/South Georgia Veterans Health System Department of Physiological Sciences College of Veterinary Medicine University of Florida Department of Neuroscience McKnight Brain Institute College of Medicine University of Florida Department of Neurology McKnight Brain Institute College of Medicine University of Florida

Our recent findings have demonstrated that rodent models of closed head traumatic brain injury exhibit comprehensive evidence of progressive and enduring orofacial allodynias, a hypersensitive pain response induced by non-painful stimulation. These allodynias, tested using thermal hyperalgesia, correlated with changes in several known pain signaling receptors and molecules along the trigeminal pain pathway, especially in the trigeminal nucleus caudalis. This study focused to extend our previous work to investigate the changes in monoamine neurotransmitter immunoreactivity changes in spinal trigeminal nucleus oralis, pars interpolaris and nucleus tractus solitaries following mild to moderate closed head traumatic brain injury, which are related to tactile allodynia, touch-pressure sensitivity, and visceral pain. Our results exhibited significant alterations in the excitatory monoamine, serotonin, in spinal trigeminal nucleus oralis and pars interpolaris which usually modulate tactile and mechanical sensitivity in addition to the thermal sensitivity. Moreover, we also detected a robust alteration in the expression of serotonin, and inhibitory molecule norepinephrine in the nucleus tractus solitaries, which might indicate the possibility of an alteration in visceral pain, and existence of other morbidities related to solitary nucleus dysfunction in this rodent model of mild to moderate closed head traumatic brain injury. Collectively, widespread changes in monoamine neurotransmitter may be related to orofacial allodynhias and headache after traumatic brain injury.

关键词： traumatic trigeminal headache alteration visceral nucleus underlying moderate stimulation possibility

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tectonic juxtaposition of crust and continental growth during orogenesis: Example from the Rengali Province, eastern India

引用

Geoscience Frontiers 2015年第4期6卷 537-555页

作者： Sankar bose Susmita Guha Gautam Ghosh Kaushik Das joydip Mukhopadhyay Department of Geology Presidency University Department of Earth and Planetary Systems Science Hiroshima University PPM Research Group Department of Geology University of Johannesburg

The southern houndary of the Singhbhum Craton witnessed multiple orogenies that juxtaposed thin slice of granulite suite of the Rengali Province against the low-grade granite-greenstone belt of the craton along the E-W trending Sukinda Thrust. The strong southerly dipping mylonitic foliation within the granulites along with the pronlinent down-dip mineral lineation, suggest a northerly-verging thrusting. Mylonitized charnockite at the contact zone contains enclaves of mafic and ultranlafic granulite, whereas granitoid gneiss contains enclaves of pelitic granulite. Mafic granulite enclaves preserve an early （SiM） foliation that formed during DiM deformation. This rock, along with the host charnockite, were intensely deformed by the D2M thrusting event and resulting S2M foliation development in both rock suites. Geothermobaronietric and pseudosection analyses show that the garnet-clinopyroxene-plagioclase- orthopyroxene-ihllenite-quartz assemblage in mafic granulite was stabilized at high-pressure and temperature conditions （10 12 kbar, 860 C） and was overprinted by a fine-grained assemblage of cli- nopyroxene-plagioclase j hornblende that developed during deconlpression （down to 5.5-7.5 I〈bar）. Matrix hornblende shows incipient breakdown to garnet-clinopyroxene-quartz intergrowth due to a granulite facies reworking. A contrasting P-T history is preserved in the pelitic granulite. The peak assemblage garnet-orthopyroxene-cordierite-quartz-rutile was stabilized at -6.0 kbar, 730 C which resulted flom heating of the mid crust magma during the D2M thrusting. The contrasting P-T histories could result flonl the tectonic juxtaposition of lowerand mid-crustal section during the D2M event. Evidences of an early orogenic imprint within the mafic granulite imply involvement of deep continental crust during southward growth of the Singhbhum Craton.

关键词： Singhbhunl cratonRengali Province Granulite enclave Tectonic juxtaposition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

BEHAVIOURAL PROFILE OF A TROOP OF PHAYRE’S LEAF MONKEY （TRACHYP1THECUS PHAYREI） IN A FRAGMENTED AND DISTURBED HABITAT, NORTHEAST INDIA

BEHAVIOURAL PROFILE OF A TROOP OF PHAYRE’S LEAF MONKEY （TR...

引用

The Xixth Congress The International Primatological Society

作者： j.bose P.C.Bhattacharjee Department of Zoology Gauhati University Guwahati-781 014 Assam INDIA. Department of Zoology Gauhati University Guwahati-781 014 Assam INDIA.

＜正＞ The behavioural study on a troop of 6 Phayre’s leaf monkeys （Trachypithecus phayrei） was undertaken for 453 hours （over 36 days） between April 2000 and March 2001 in a 20.1 ha fragmented, bamboo dominated forest patch surrounded on all sides by paddy fields in southern Assam, India. 10 min. scan sampling method was used from dawn to dusk for six consecutive days in six locally known seasons

关键词： Behaviour ecology Phayre’s leaf monkey

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Feasibility of pancreatectomy following high-dose proton therapy for unresectable pancreatic cancer

引用

World journal of Gastrointestinal Surgery 2017年第4期9卷 103-108页

作者： Kathryn E Hitchcock R Charles Nichols Christopher G Morris Debashish bose Steven j Hughes john A Stauffer Scott A Celinski Elizabeth A johnson Robert A Zaiden Nancy P Mendenhall Michael S Rutenberg Department of Radiation Oncology University of Florida Department of Surgical Oncology UF Health Cancer Center-Orlando Health Department of Surgery University of Florida Department of Surgery Mayo Clinic Department of Surgery Baylor University Medical Center at Dallas Department of Hematology/Oncology Mayo Clinic Department of Hematology/Oncology Baptist Health

AIM To review surgical outcomes for patients undergoing pancreatectomy after proton therapy with concomitant capecitabine for initially unresectable pancreatic *** From April 2010 to September 2013,15 patients with initially unresectable pancreatic cancer were treated withproton therapy with concomitant capecitabine at 1000 mg orally twice daily. All patients received 59.40 Gy(RBE) to the gross disease and 1 patient received 50.40 Gy(RBE) to high-risk nodal targets. There were no treatment interruptions and no chemotherapy dose reductions. Six patients achieved a radiographic response sufficient to justify surgical exploration,of whom 1 was identified as having intraperitoneal dissemination at the time of surgery and the planned pancreatectomy was aborted. Five patients underwent resection. Procedures included:Laparoscopic standard pancreaticoduodenectomy(n = 3),open pyloris-sparing pancreaticoduodenectomy(n = 1),and open distal pancreatectomy with irreversible electroporation(IRE) of a pancreatic head mass(n = 1). RESULTS The median patient age was 60 years(range,51-67). The median duration of surgery was 419 min(range,290-484),with a median estimated blood loss of 850 cm^3(range,300-2000),median ICU stay of 1 d(range,0-2),and median hospital stay of 10 d(range,5-14). Three patients were re-admitted to a hospital within 30 d after discharge for wound infection(n = 1),delayed gastric emptying(n = 1),and ischemic gastritis(n = 1). Two patients underwent R0 resections and demonstrated minimal residual disease in the final pathology specimen. One patient,after negative pancreatic head biopsies,underwent IRE followed by distal pancreatectomy with no tumor seen in the specimen. Two patients underwent R2 resections. Only 1 patient demonstrated ultimate local progression at the primary site. Median survival for the 5 resected patients was 24 mo(range,10-30).CONCLUSION Pancreatic resection for patients with initially unresectable cancers is feasible after

关键词： Pancreatic cancer Pancreatectomy Pancreas Proton therapy Radiotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：