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Transcription factors CncC and Maf connect the molecular network between pesticide resistance and resurgence of pest mites

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Insect Science 2022年第3期29卷 801-816页

作者： Guang-Mao shen Shi-Yuan Ou Chuan-Zhen Li Kai-Yang Feng jin-Zhi Niu Michael j.Adang Lin He Key Laboratory of Entomology and Pest Control Engineering College of Plant ProtectionSouthwest UniversityChongqingChina Academy of Agricultural Sciences Southwest UniversityChongqingChina State Cultivation Base of Crop Stress Biology for Southern Mountainous Land of Southwest University Southwest UniversityChongqingChina Department of Entomology University of GeorgiaAthensGeorgiaUSA

Pesticide resistance and resurgence are serious problems often occurring simultaneously in the *** our long-term study of a fenpropathrin-resistant strain of Tetranychus cinnabaribus,enhancement of detoxification and modified fecundity mechanisms were both *** we investigate the network across these two mechanisms and find a key node between resistance and *** show that the ecdysone pathway is involved in regulating the fecundity of *** concentration change of ecdysone is consistent with the fecundity curve;the concentration of ecdysone is higher in the fenpropathrin-resistant strain which has stronger *** enhancement of ecdysone is due to overexpression of two P450 genes(CYP314A1 and CYP315A1)in the ecdysone synthesis *** expression of these CYP genes resulted in lower concentration of ecdysone,reduced expression of vitellogenin,and reduced fecundity of *** expression of CYP315A1 is regulated by transcription factors Cap-n-collar isoform C(CncC)and Musculoaponeurotic fibrosarcoma protein(Maf),which are involved in regulating other P450 genes functioning in detoxification of fenpropathrin in ***.A similar regulation is established in citrus pest mite Panonychus citri showing that the CncC pathway regulates expression of PcCYP315Al,which affects mite *** factors are activated to upregulate detoxification genes facilitating pesticide resistance,while the“one to multiple”regulation mode of transcription factors simultaneously increases expression of metabolic enzyme genes in hormone pathways and alters the physiology of *** is an important response of arthropods to pesticides which leads to resistance and population resurgence.

关键词： resistance resurgence Tetranychus cinnabarinus transcription factor

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Microstructures and mechanical properties of Ti3Al/Ni-based superalloy joints brazed with AuNi filler metal

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journal of Materials Science & Technology 2019年第9期35卷 2070-2078页

作者： H.S. Ren H.P.Xiong W.M. Long B. Chen Y.X. shen j. Pang Welding and Plastic Forming Division Beijing Institutes of Aeronautical MatericalBeijing 100095China State Key Laboratory of Advanced Brazing Filler Metals and Technology Zhengzhou Research Institute of Mechanical EngineeringZhengzhou 450001 China Department of Material Science and Engineering Beihang UniversityBeijing 100191China

For the purpose of high-temperature service and the weight reduction in aviation engineering applications, the dissimilar joining of Ti3Al-based alloy to Ni-based superalloy (GH536) was conducted using Au-17.5Ni (wt%) brazing filler metal. The microstructure and chemical composition at the interfaces were investigated by scanning electron microscope, X-ray diffraction and transmission electron microscope. The diffusion behaviors of elements were analyzed as well. The results indicated that the Ti3Al/GH536 joint microstructure was characterized by multiple layer structures. Element Ni from Au-Ni filler metal reacted with Ti3Al base metal, leading to the formation of AlNi2Ti and NiTi compounds. Element Ni from Ti3Al base metal reacted with Ni and thus Ni3Nb phase was detected in the joint central area. Due to the dissolution of Ni-based superalloy,(Ni,Au) solid solution ((Ni,Au)ss) and Ni-rich phase were visible adjacent to the superalloy side. The average tensile strength of all the joints brazed at 1253 K for 5-20 min was above 356 MPa at room-temperature. In particular, the joints brazed at 1253 K/15 min presented the maximum tensile strength of434 MPa at room-temperature, and the strength of 314 MPa was maintained at 923 K. AlNi2Ti compound resulted in the highest hardness area and the fracture of the samples subjected to the tensile test mainly occurred in this zone.

关键词： Ti3Al-based alloy Ni-based superalloy Brazing Microstructure Tensile strength

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Holomorphic Maps from Sasakian Manifolds into Khler Manifolds

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Chinese Annals of Mathematics,Series B 2013年第4期34卷 575-586页

作者： Bin shen Yibing shen Xi ZHANG Department of Mathematics Southeast University Department of Mathematics Zhejiang University Department of Mathematics Zhejiang University

The authors consider ±（Φ, j）-holomorphic maps from Sasakian manifolds into Koihler manifolds, which can be seen as counterparts of holomorphic maps in Kiihler ge- ometry. It is proved that those maps must be harmonic and basic. Then a Schwarz lemma for those maps is obtained. On the other hand, an invariant in its basic homotopic class is obtained. Moreover, the invariant is just held in the class of basic maps.

关键词： Sasakian manifold Harmonic Schwarz lemma Homotopic invariant

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Electron tomography for sintered ceramic materials by a neural network algebraic reconstruction technique

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journal of Materials Science & Technology 2022年第5期100卷 75-81页

作者： R.H.shen Y.T.He W.Q.Ming Y.Zhang X.D.Xu j.H.Chen Centre for High Resolution Electron Microscopy College of Materials Science and EngineeringHunan UniversityChangsha 410082China

The missing wedge effect in electron tomography introduces various types of artifacts in the tomograms and lowers the reconstruction resolution and *** artifacts produced in tomographic reconstruction of bulk materials can be very severe,particularly for sintered bulk ceramic materials in which there are often nano-pores or pore-like microstructure ***,we report a neural network algebraic reconstruction algorithm with no prior knowledge to perform electron tomography for a sintered SiC material with nano carbon *** results show that the proposed algorithm has a great suppressive effect on the missing wedge artifacts and a high tolerance for *** information in the missing wedge can be partly recovered by this ***,both the shape of the bulk SiC specimen and its irregular inner pore-like features are correctly retrieved in the obtained 3D *** study shows the effectiveness of the neural network algorithm for improving the reconstruction accuracy of electron tomography,in order to reveal sophisticated 3D microstructures generally existing in sintered ceramic materials.

关键词： Neural network Missing wedge Electron tomography Sintered ceramics

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Self-induced birefringence of white-light continuum generated by interaction of focused femtosecond laser pulses with fused silica

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High Power Laser Science and Engineering 2020年第2期8卷 71-76页

作者： j.Qian G.D.Wang K.Y.Lou D.Y.shen Q.Fu Q.Z.Zhao State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

White-light continuum can be induced by the interaction of intense femtosecond laser pulses with condensed *** using two orthogonal polarizers,a self-induced birefringence of continuum is observed when focusing femtosecond laser pulses into bulk fused *** is,the generated white-light continuum is synchronously modulated anisotropically while propagating in fused ***-resolved detection confirms that self-induced birefringence of continuum shows a growth and saturation feature with time *** adjusting laser energy,the transmitted intensity of continuum modulated by self-induced birefringence also varies *** analysis with time evolution indicates that it is the focused femtosecond laser pulses that induce anisotropic microstructures in bulk fused silica,and the anisotropic structures at the same time modulate the generated continuum.

关键词： femtosecond laser pulses fused silica self-induced birefringence white-light continuum

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Non-equilibrium thermodynamic analysis of coupled heat and moisture transfer across a membrane

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Chinese journal of Chemical Engineering 2022年第4期35卷 497-506页

作者： Zhijie shen jingchun Min Key Laboratory for Thermal Science and Power Engineering of Ministry of Education Department of Engineering MechanicsTsinghua UniversityBeijing 100084China

Non-equilibrium thermodynamics theory is used to analyze the transmembrane heat and moisture transfer process,which can be observed in a membrane-type total heat exchanger(THX).A theoretical model is developed to simulate the coupled heat and mass transfer across a membrane,total coupling equations and the expressions for the four characteristic parameters including the heat transfer coefficient,molardriven heat transfer coefficient,thermal-driven mass transfer coefficient,and mass transfer coefficient are derived and provided,with the Onsager’s reciprocal relation being confirmed to verify the rationality of the *** are conducted to investigate the effects of the membrane property and air state on the coupling transport *** results show that the four characteristic parameters directly affect the transmembrane heat and mass fluxes:the heat and mass transfer coefficients are both positive,meaning that the temperature difference has a positive contribution to the heat transfer and the humidity ratio difference has a positive contribution to the mass *** molar-driven heat transfer and thermal-driven mass transfer coefficients are both negative,implying that the humidity ratio difference acts to reduce the heat transfer and the temperature difference works to diminish the mass *** mass transfer affects the heat transfer by 1%–2%while the heat transfer influences the mass transfer by7%–14%.The entropy generation caused by the temperature difference-induced heat transfer is much larger than that by the humidity difference-induced mass transfer.

关键词： Membrane Non-equilibrium thermodynamics Heat transfer Mass transfer Coupling effect

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Ca-and Mg-rich waste as high active carrier for chemical looping gasification of biomass

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Chinese journal of Chemical Engineering 2021年第10期34卷 145-154页

作者： Xin Niu Laihong shen School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing 210094China Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjing 210096China

Chemical looping gasification(CLG)is a promising technology for high-quality syngas *** key issue to successful CLG is the selection of high-performance oxygen *** this study,several Ca-and Mg-rich steelmaking wastes from steel industry,such as blast furnace slag(BF slag),blast furnace dust(BF dust)and Linz-Donawitz converter slag(LD slag),were used as oxygen carriers in chemical looping gasification of *** results showed that the reducibility of Ca-and Mg-rich waste,especially LD slag and BF dust,was superior to that of *** long-term operation,the cyclic stability of steelmaking waste was *** dust showed a poor stability,while the other carrier(hematite,BF slag or LD slag)presented an excellent stability during multiple redox cycles in spite of partial sintering and ***,the effects of supply oxygen coefficient(O/B ratio)and reaction temperature on CLG of biomass were *** results revealed that Ca-and Mg-rich waste exhibited a higher syngas production compared to *** higher performance could be attributed to the improved reduction rate of Fe2O3 and gasification rate of biomass by Ca or Mg in steelmaking *** addition,LD slag exhibited the higher gas value at the O/B ratio of 1 at 900℃.As a consequence,LD slag was an appropriate oxygen carrier for CLG of biomass in terms of perfect reducibility,superior cyclic stability and high reactivity.

关键词： Biomass Syngas Gasification Ca-and Mg-rich waste Chemical looping

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Pyrometallurgical recycling of spent lithium-ion batteries from conventional roasting to synergistic pyrolysis with organic wastes

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journal of Energy Chemistry 2023年第10期85卷 547-561,I0014页

作者： Chao Pan Yafei shen China Energy Science and Technology Research Institute Co.Ltd. Nanjing 210023JiangsuChina jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control(AEMPC) Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environmental Science and EngineeringNanjing University of Information Science and TechnologyNanjing 210044JiangsuChina

The synergistic pyrolysis has been increasingly used for recycling spent lithium-ion batteries(LIBs)and organic wastes(hydrogen and carbon sources),which are in-situ transformed into various reducing agents such as H_(2),CO,and char via carbothermal and/or gas thermal *** with the conventional roasting methods,this“killing two birds with one stone”strategy can not only reduce the cost and energy consumption,but also realize the valorization of organic *** paper concluded the research progress in synergistic pyrolysis recycling of spent LIBs and organic *** the one hand,valued metals such as Li,Co,Ni,and Mn can be recovered through the pyrolysis of the cathode materials with inherent organic materials(e.g.,separator,electrolyte)or graphite *** the pyrolysis process,the organic materials are decomposed into char and gases(e.g.,CO,H_(2),and CH_(4))as reducing agents,while the cathode material is decomposed and then converted into Li_(2)CO_(3) and low-valent transition metals or their oxides via in-situ thermal *** formed Li_(2)CO_(3) can be easily recovered by the water leaching process,while the formed transition metals or their oxides(e.g.,Co,CoO,Ni,MnO,etc.)can be recovered by the reductant-free acid leaching or magnetic separation *** the other hand,organic wastes(e.g.,biomass,plastics,etc.)as abundant hydrogen and carbon sources can be converted into gas(e.g.,H_(2),CO,etc.)and char via *** cathode materials are decomposed and subsequently reduced by the pyrolysis gas and *** addition,the pyrolysis oil and gas can be upgraded by catalytic reforming with the active metals derived from cathode ***,great challenges are proposed to promote this promising technology in the industrial applications.

关键词： Synergistic pyrolysis Spent LIBs Biomass Recycling Reduction roasting

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Modeling solubility of oxaprozin and irbesartan in biorelevant complex solutions based on a combination of pH-dependent and micellar solubilization models

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Chinese journal of Chemical Engineering 2024年第8期72卷 34-43页

作者： Chen shen Yuanhui ji jiangsu Province Hi-Tech Key Laboratory for Biomedical Research School of Chemistry and Chemical EngineeringSoutheast UniversityNanjing 211189China

Biological solubility is one of the important basic parameters in the development process of poorly soluble drugs,but the current measurement methods are mainly based on a large number of experiments,which are time-consuming and *** is still a lack of effective theoretical models to accurately describe and predict the biological solubility of drugs to reduce ***,in this study,osaprazole and irbesartan were selected as model drugs,and their solubility in solutions containing surfactants and biorelevant media was measured *** calculating the parameters of each component using the perturbed-chain statistical associating fluid theory(PC-SAFT)model,combined with pH-dependent and micellar solubilization models,the thermodynamic phase behavior of the two drugs was successfully modeled,and the predicted results were in good agreement with the experimental *** results demonstrate that the model combination used provides important basic parameters and theoretical guidance for the development and screening of poorly soluble drugs and related formulations.

关键词： Biorelevant media pH-dependent solubility Micellar solubilization PC-SAFT Active pharmaceutical ingredients

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Research on high-performance English translation based on topic model

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Digital Communications and Networks 2023年第2期9卷 505-511页

作者： Yumin shen Hongyu Guo Zhejiang Gongshang University Hangzhou310018China Graduate School of Education University of Perpetual Help System DALTAMetro Manila1740Philippines

Retelling extraction is an important branch of Natural Language Processing(NLP),and high-quality retelling resources are very helpful to improve the performance of machine ***,traditional methods based on the bilingual parallel corpus often ignore the document background in the process of retelling acquisition and *** order to solve this problem,we introduce topic model information into the translation mode and propose a topic-based statistical machine translation method to improve the translation *** this method,Probabilistic Latent Semantic Analysis(PLSA)is used to obtains the co-occurrence relationship between words and documents by the hybrid matrix *** we design a decoder to simplify the decoding *** show that the proposed method can effectively improve the accuracy of translation.

关键词： Machine translation Topic model Statistical machine translation Bilingual word vector Retelling

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