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国际医学放射学杂志 2024年第1期 129-129页

作者： L.Zhang H.R.E j.huang j.Q.Wu Q.Li L.K.Hou 刘莹莹

摘要目的 PET/CT在非小细胞肺癌（NSCLC）新辅助化疗免疫治疗后预测ypN2病变的表现尚未见报道。该多中心研究分析了PET/CT在评估这些病人ypN2病变中的作用。方

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Do specific ultrasonography features identified at the time of early pregnancy loss predict fetal chromosomal abnormality? e A systematic review and meta-analysis

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Genes & Diseases 2019年第2期6卷 129-137页

作者： j.huang W.Zhu j.Tang S.H.Saravelos L.C.Y.Poon T.C.Li Department of Obstetrics and Gynaecology The First Affiliated Hospital of Chongqing Medical UniversityChongqing400016China Department of Obstetrics and Gynaecology The Chinese University of Hong KongHong Kong SARChina IVF Unit Hammersmith HospitalImperial College Healthcare NHS TrustLondonUK

To investigate the association of specific ultrasonography features identified during the diagnosis of early pregnancy loss(EPL)and abnormal karyotype.This was a systematic review and meta-analysis conducted in accordance with PRISMA criteria.We searched PubMed,Cochrane and Ovid MEDLINE from 1977 to jan 2017 to identify the articles that described EPL with karyotype and ultrasonography features.Risk differences were pooled to estimate the chromosomal abnormality rates in ultrasonography features,including pre-embryonic,enlarged yolk sac(YS),short crown rump length(CRL),small gestational sac(GS),symmetrical arrested growth embryo,or gestational sac with only a YS.Quality assessment of included studies was performed using Strengthening the Reporting of Observational Studies in Epidemiology(STROBE)checklists for Observational Studies(2007 version).Thirteen studies were included in the meta-analysis.Chromosomal abnormality was more likely to occur in embryonic EPL and enlarged YS.On the other hand,short CRL,small GS,symmetrical arrested growth embryo,or gestational sac with only a YS,were not associated with an increased risk of fetal chromosomal abnormality.Ultrasonography features at the time of diagnosis of EPL have limited predictive value of fetal chromosomal abnormality.

关键词： Ultrasonography Early pregnancy loss Chromosomal abnormality Predictive value

双层探测器光谱CT预测肺腺癌气腔播散能否提供附加价值？一项初步研究

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国际医学放射学杂志 2024年第4期 504-504页

作者： B.C.Liu H.Y.Ma j.huang Y.W.Luo W.B.Zhang W.W.Deng 沈枨

摘要目的探讨双层探测器光谱CT(DLCT)在临床预测肺腺癌气腔播散（STAS）方面的价值。方法回顾性分析225例肺腺癌病人的人口统计学、临床、病理、传统CT及光

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Depolarization of intense laser beams by dynamic plasma density gratings

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高功率激光科学与工程:英文版 2023年第3期11卷 48-56页

作者： Y.X.Wang S.M.Weng P.Li Z.C.Shen X.Y.jiang j.huang X.L.Zhu H.H.Ma X.B.Zhang X.F.Li Z.M.Sheng j.Zhang Key Laboratory for Laser Plasmas(MoE) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Collaborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghaiChina Research Center of Laser Fusion of China Academy of Engineering Physics MianyangChina College of Physics and Electronics Engineering Northwest Normal UniversityLanzhouChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina

As a typical plasma-based optical element that can sustain ultra-high light intensity,plasma density gratings driven by intense laser pulses have been extensively studied for wide applications.Here,we show that the plasma density grating driven by two intersecting driver laser pulses is not only nonuniform in space but also varies over time.Consequently,the probe laser pulse that passes through such a dynamic plasma density grating will be depolarized,that is,its polarization becomes spatially and temporally variable.More importantly,the laser depolarization may spontaneously take place for crossed laser beams if their polarization angles are arranged properly.The laser depolarization by a dynamic plasma density grating may find application in mitigating parametric instabilities in laser-driven inertial confinement fusion.

关键词： depolarization high-power laser plasma density grating

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肥厚型心肌病MRI T1 mapping：对无延迟钆剂增强及血流动力学障碍病人的评价（DOI:10.19300/j.2020.r0203）

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国际医学放射学杂志 2020年第2期 237-238页

作者： j.Xu B.Zhuang A.Sirajuddin S.Li j.huang G.Yin 李璐 Department of Magnetic Resonance Imaging Fuwai Hospital State Key Laboratory of Cardiovascular Disease Chinese Academy of Medical Sciences and Peking Union Medical College

无延迟钆剂增强(LGE)和血流动力学障碍的肥厚型心肌病(HCM)病人,其固有心肌T1mapping和细胞外容积(ECV)分数值目前尚不清楚。目的用固有心肌T1mapping

关键词： MRI T1 mapping 肥厚型心肌病 DOI.19300/j.2020.r0203 流动力学

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潮流背后的思考——青少年性别观念的改变

大众心理学 2008年第6期 14-15页

作者：唐淦琦孟琳芳 j.huang

“好男”、“超女”、“我型我秀”……相信这些名字你早已烂熟于心。如果要问李宇春、师洋他们给你留下最深刻的印象会是什么？你的回答会是时尚，勇气，还是“中性风”？

关键词：性别观念青少年 “超女” 时尚

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Aberrant DKK3 Expression in the Oral Leukoplakia and Oral Submucous Fibrosis: A Comparative Immunohistochemical Study

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Aberrant DKK3 Expression in the Oral Leukoplakia and Oral Su...

The technology for detection of gamma-ray burst with GECAM satellite

2018口腔病理年会暨第十二次全国口腔病理学术会议

作者： T.Al-dhohrah M.Mashrah Z.Yao j.huang Department of Oral Pathology Xiangya Stomatology Hospital Central South University Clinical fellow Department of Oral and Maxillofacial Surgery Xiangya Hospital College of Stomatology Central South University

【Objective】: We aimed to assess and compare the expression of Dickkopf homolog 3(DKK3), a possible tumor suppressor gene(TSG), in oral leukoplakia(OLK) and oral submucous fibrosis(OSF) using immunohistochemistry. 【Methods】: Seventy-five cases of normal oral mucosa(NOM), OLK, OSF, and squamous cell carcinoma(OSCC) were studied. 【Results】: DKK3 was expressed in all cases of NOM, OLK and OSCC. There was steady increases in the percentage of the positive cells progressing toward OSCC. The expression was localized in the cytoplasm and cell membrane of cell affected by OLK with mild dysplasia and OLK with severe dysplasia. No significant association was observed between DKK3 expression and dysplastic status of OLK. Loss of DKK3 expression was observed in 15 of 30 cases in the OSF group, which was significantly associated with histological grade of OSF(P<0.0001). The percentage of positive cells gradually declined with the increasing severity of epithelial atrophy. A significant difference(P<0.01) was observed when comparing DKK3 expression among different groups of OLK and OSF cases. 【Conclusion】: DKK3 may have diverse expressions in oral premalignant lesions. Loss of DKK3 expression in dysplastic/advanced stage of OSF may imply a high risk of progression to oral cancer.

关键词： Oral leukoplakia oral submucous fibrosis DKK3 immunohistochemistry

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Radiation Detection Technology and Methods 2022年第1期6卷 12-25页

作者： X.Q.Li X.Y.Wen Z.H.An C.Cai Z.Chang G.Chen C.Chen Y.Y.Du M.Gao R.Gao K.Gong D.Y.Guo j.j.He D.j.Hou Y.G.Li C.Y.Li G.Li L.Li X.F.Li M.S.Li X.H.Liang X.j.Liu Y.Q.Liu F.j.Lu H.Lu B.Meng W.X.Peng F.Shi X.L.Sun H.Wang j.Z.Wang Y.S.Wang H.Z.Wang X.Wen S.Xiao S.L.Xiong Y.B.Xu Y.P.Xu S.Yang j.W.Yang Q.B.Yi D.L.Zhang Fan Zhang S.N.Zhang C.Y.Zhang C.M.Zhang Fei Zhang X.Y.Zhao Y.Zhao X.Zhou C.S.Zhang j.P.Yu L.Chang K.K.Zhang j.huang Y.M.Chen X.B.Han Institute of High Energy Physics CASBeijing 100049China Xiangtan University Xiangtan 411105China Beijing Normal University Beijing 110875China Beijing Glass Research Institute Beijing 101100China Innovation Academy for Microsatellites of CAS Shanghai 201204China

Introduction The main physical objective of the GECAM satellite is to detect gamma-ray bursts,which is related to gravitational waves of double compact object mergers.The GECAM satellite also detects and investigates various bursts of high-energy celestial bodies.Purposes and methods In this study,we designed,developed and calibrated the payload and launched it into orbit with GECAM satellite.The payload consists of the gamma ray detector(GRD,for detecting 4 keV–4 MeV X/γray),the charged particle detector(CPD,for detecting 150 keV–5 MeV charged particle),and the electronic box(EBOX).The all-sky field coverage is achieved via two 229-degree large-area satellites positioned 180 degrees apart and are on opposite sides of the geo-center.Each satellite is equipped with 25 GRDs and 8 CPDs;thus,the satellite can identify charged particle bursts in space.Gamma-ray detectors adopt lanthanum bromide crystal technology combined with silicon photomultipliers.This is the first time that this technology was used massively in space detectors.Conclusions The GECAM satellite can quickly determine the direction of gamma-ray bursts(positioning)via indexing and fitting method,while the transmit variability,energy spectrum and direction of the gamma-ray bursts guide subsequent observations through the Beidou-3 RDSS in quasi-real time.It will play an important role in the study of high energy celestial bursts.

关键词： GECAM Gamma-ray burst Lanthanum bromide crystal Silicon photomultiplier Beidou short message

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外延铜薄膜的化学气相沉积法制备与表征

外延铜薄膜的化学气相沉积法制备与表征

Anchanling reduces pathology in a lactacystin-induced Parkinson's disease model

TEIM2015第六届无机材料结构、性能及测试表征技术研讨会

作者： R.Tu j.huang S.Zhang L.M.Zhang 武汉理工大学材料复合新技术国家重点实验室

以Cu(acac)2为前驱体在氧化铝单晶基板上用化学气相沉积法进行铜薄膜的外延生长。通过X射线衍射技术,扫描电子显微镜对铜薄膜的取向度,结品性进行分析,阐述了铜和氧化铝的品格匹配机制和铜薄膜外延生长的机理,根据吉布斯自由能的计算对...

以Cu(acac)2为前驱体在氧化铝单晶基板上用化学气相沉积法进行铜薄膜的外延生长。通过X射线衍射技术,扫描电子显微镜对铜薄膜的取向度,结品性进行分析,阐述了铜和氧化铝的品格匹配机制和铜薄膜外延生长的机理,根据吉布斯自由能的计算对反应进一步说明。各项结果表明以Cu(acac)2化学气相沉积法制备的铜薄膜具有高取向度,结晶性好,是当前微型电路和梯度材料的优质前驱体,为铜薄膜的后续应用开辟了新的途径。

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Neural Regeneration Research 2012年第3期7卷 165-170页

作者： Yinghong Li Zhengzhi Wu Xiaowei Gao Qingwei Zhu Yu jin Anmin Wu Andrew C. j.huang Shenzhen Second People＇s Hospital First Affiliated Hospital of Shenzhen University Shenzhen 518035 Guangdong Province China Shenzhen Institute of Gerontology Second Clinical Medical College Jinan University Shenzhen 518020 Guangdong Province China Larry Hillblom Islet Research Center David Geffen School of Medicine UCLA Los Angeles CA 90024 USA

A rat model of Parkinson＇s disease was induced by injecting lactacystin stereotaxically into the left mesencephalic ventral tegmental area and substantia nigra pars compacta. After rats were intragastrically perfused with Anchanling, a Chinese medicine, mainly composed of magnolol, for 5 weeks, when compared with Parkinson’s disease model rats, tyrosine hydroxylase expression was increased, α-synuclein and ubiquitin expression was decreased, substantia nigra cell apoptosis was reduced, and apomorphine-induced rotational behavior was improved. Results suggested that Anchanling can ameliorate Parkinson＇s disease pathology possibly by enhancing degradation activity of the ubiquitin-proteasome system.

关键词： Parkinson＇s disease Anchanling ubiquitin-proteasome system α-synuclein tyrosine hydroxylase cell apoptosis

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