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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon j.Brown Rafael j.yáñez-Muñoz heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

青少年特发性脊柱侧凸病人直立位对小脑扁桃体水平的影响

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国际医学放射学杂志 2015年第5期 506-506页

作者： R.K.L.Lee j.F.Griffith j.h.y.leung W.C.W.Chu T.P.Lam B.K.W.Ng 张鹏 Faculty of Medicine The Chinese University of HongKongPrince of Wales Hospital

摘要目的本研究的目的是调查青少年特发性脊柱侧凸(AIS)病人直立位对小脑扁桃体水平的影响。材料与方法25例临床诊断为AIS的病人和18名正常对照组均行仰卧位及直立位0.25 T MR检查。测量小脑扁桃体尖端与颅底枕后连线(BO线)的相对位置,... 详细信息

摘要目的本研究的目的是调查青少年特发性脊柱侧凸(AIS)病人直立位对小脑扁桃体水平的影响。材料与方法25例临床诊断为AIS的病人和18名正常对照组均行仰卧位及直立位0.25 T MR检查。测量小脑扁桃体尖端与颅底枕后连线(BO线)的相对位置,计量单位为毫米。结果 18名正常对照组无论仰卧位或直立位,小脑扁桃体均不低于BO

关键词：小脑扁桃体直立位 AIS 特发性脊柱侧凸病人

Aluminum-air battery with cotton substrate:Controlling the discharge capacity by electrolyte pre-deposition

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Green Energy & Environment 2023年第3期8卷 757-766页

作者： Wending Pan yifei Wang holly y.h.Kwok Dennis y.C.leung Department of Mechanical Engineering The University of Hong KongHong KongChina

Conventional Al-air battery has many disadvantages for miniwatt applications,such as the complex water management,bulky electrolyte storage and potential leakage ***,the self-corrosion of Al anode continues even when the electrolyte flow is stopped,leading to great Al *** tackle these issues,an innovative cotton-based aluminum-air battery is developed in this *** of flowing alkaline solution,cotton substrate pre-deposited with solid alkaline is used,together with a small water reservoir to continuously wet the cotton and dissolve the alkaline *** this manner,the battery can be mechanically recharged by replacing the cotton substrate and refilling the water reservoir,while the thick aluminum anode can be reused for tens of times until complete *** cotton substrate shows excellent ability for the storage and transportation of alkaline electrolyte,leading to a high peak power density of 73 mW cm^(-2) and a high specific energy of 930 mW h g^(-1).Moreover,the battery discharge capacity is found to be linear to the loading of pre-deposited alkaline,so that it can be precisely controlled according to the mission profile to avoid Al ***,a two-cell battery pack with common water reservoir is developed,which can provide a voltage of 2.7 V and a power output of 223.8 *** further scaling-up and stacking,this cotton-based Al-air battery system with low cost and high energy density is very promising for recharging miniwatt electronics in the outdoor environment.

关键词： Al-air battery Cotton-based Electrolyte pre-deposition Capacity control Miniwatt electronics

Study on the wind field and pollutant dispersion in street canyons using a stable numerical method

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journal of Environmental Sciences 2005年第3期17卷 488-490页

作者： Dennis y.C. leung Department of Mechanical Engineering the University of Hong Kong Hong Kong China

A stable finite element method for the time dependent Navier-Stokes equations was used for studying the wind flow and pollutant dispersion within street canyons. A three-step fractional method was used to solve the velocity field and the pressure field separately from the governing equations. The Streamline Upwind Petrov-Galerkin(SUPG) method was used to get stable numerical results. Numerical oscillation was minimized and satisfactory results can be obtained for flows at high Reynolds numbers. Simulating the flow over a square cylinder within a wide range of Reynolds numbers validates the wind field model. The Strouhal numbers obtained from the numerical simulation had a good agreement with those obtained from experiment. The wind field model developed in the present study is applied to simulate more complex flow phenomena in street canyons with two different building configurations. The results indicated that the flow at rooftop of buildings might not be assumed parallel to the ground as some numerical modelers did. A counter-clockwise rotating vortex may be found in street canyons with an inflow from the left to right. In addition, increasing building height can increase velocity fluctuations in the street canyon under certain circumstances, which facilitate pollutant dispersion. At high Reynolds numbers, the flow regimes in street canyons do not change with inflow velocity.

关键词： finite element method Streamline Upwind Petrov-Galerkin method three-step fractional method

Spin-correlation function of the fully frustrated Ising model and ±j Ising spin glass on a square lattice

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Chinese Physics B 2013年第6期22卷 549-552页

作者： M y Ali j Poulter Department of Mathematics Faculty of ScienceMahidol University

In this work we study the correlation function of the ground state of a two-dimensional fully frustrated Ising model as well as spin glass. The Pfaffian method is used to calculate free energy and entropy as well as the correlation function. We estimate the exponent of spin correlation function for the fully frustrated model and spin glass. In this paper an overview of the latest results on the spin correlation function is presented.

关键词： spin glass correlation function exponent square lattice

Characteristics of urban ozone level in hong kong

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journal of Environmental Sciences 2001年第1期13卷 1-7页

作者： D.y.C.leung D.N.ZhANG Department of Mechanical Engineering The University of Hong KongPokfulam RoadHong KongChina Research Institute of Environmental Engineering East China University of Science and TechnologyShanghai 200237China

The long term trend of ozone level in hong Kong has been investigated. One of the characteristics of ozone level in hong Kong is the existence of autumn maximum and summer minimum. Observations of the diurnal variation of ozone level have been made in different area categories. There are early morning peak and afternoon peak occurred in the diurnal variation, which are different from some metropolitans where only an afternoon peak is observed. A negative correlation coefficient was found between monthly ozone level with nitric oxide level. On the contrary, there is a positive correlation between ozone and nitrogen dioxide. The positive correlation coefficient between nitric oxide and nitrogen dioxide shows that the total amount of nitric oxide emitted from a series of moving and fixed sources greatly exceeded the stoichiometric amount of ozone formed from chemical reactions of precursors and long distance transportation.

关键词： ozone urban air pollution hong kong China

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

Interference with the formation of the epididymal microenvironment——a new strategy for male contraception?

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Asian journal of Andrology 2000年第1期2卷 39-45页

作者： X.D.Gong G.P.h.leung B.L.y.Cheuk P.y.D.Wong Department of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong ChinaDepartment of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong ChinaDepartment of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong ChinaDepartment of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong China

The cystic fibrosis transmembrane conductance regulator (CFIR) or the small conductance cAMP-activated chlo-ride channel encoded by the CFTR gene has been shown to play an important role in the formation of the epididymalfluid microenvironment. Recent work in our laboratory has shown that this protein is also expressed by developing germcells indicating a role of this protein in spermatogenesis. In view of the fact that the CFTR gene has a far reaching andwidespread effect on human reproduction, understanding the role of CFTR in the male reproductive tissues and its inter-vention by pharmacological agents can open a new avenue of research into the development of novel male contracep-tives. (Asian j Androl 2000; 2: 39 - 45 )

关键词： epididymis cyclooxygenase contraception cystic fibrosis transmembrane conductance regulator

Mechanistic study of vacuum UV catalytic oxidation for toluene degradation over CeO_(2) nanorods

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Green Energy & Environment 2022年第3期7卷 533-544页

作者： Muyan Wu yingguang Zhang haibao huang Dennis y.C.leung Department of Mechanical Engineering The University of Hong KongPokfulam RoadHong KongChina School of Environmental Science and Engineering Sun Yat-sen UniversityGuangzhou510275China

The present study specifically investigates vacuum ultraviolet (VUV) catalytic oxidation for toluene degradation over CeO_(2) *** effects of ultraviolet photocatalytic oxidation (UV-PCO) and ozone catalytic oxidation (OZCO) were manifested in the results of toluene removal and COx generation,while the combination of UV-PCO andOZCO (UV-OZCO) did not lead to improvement of *** the processes contribute to ozone decomposition,but no obvious synergetic effects of the different processes can be *** analysis results indicated that more toluene was oxidized into by-products,such as benzyl alcohol and benzaldehyde,by UV-OZCO rather than forming *** hydroxyl radical (·Oh) and superoxide radical (·O_(2)^(-)) were found in all the processes of the VUV-PCO-OZCO system(combination of VUV photolysis,UV-PCO,OZCO and UV-OZCO processes).In the UV-OZCO process,the formation of hydroxyl radical was promoted,while that of superoxide radical was impeded,resulting in lower mineralization level of *** mechanistic study of toluene degradation over CeO_(2) nanorods in the VUV-PCO-OZCO system revealed that with the formation of·O_(2)^(-)and·Oh,toluene is first oxidized to intermediates,followed by further ring–opening reaction and,finally,degradation into CO_(2) and h_(2)***_(2) nanorods function as both ozonation catalyst and photocatalyst,and the redox pair of Ce^(3+)and Ce^(4+)are interconvertible and can keep a balance.

关键词： toluene catalytic vacuum

Comments on“hepatic radioembolization with yttrium-90 glass microspheres for treatment of primary liver cancer”by Cao et al,Chin Med j 1999;112:430-432

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Chinese Medical journal 2001年第4期114卷 97-98页

作者： Sho Wy Lau WT leung Chinese Univ hong Kong Prince Wales Hosp Dept Surg Shatin Hong Kong Peoples R China Chinese Univ hong Kong Prince Wales Hosp Dept Clin Oncol Shatin Hong Kong Peoples R China

Editors,　　We would like to congratulate Cao and his colleagues on the extremely good mean survival rate of 19.5 months achieved in 17 patients with non-resectable liver cancer (16 primary and 1 metastatic).1　Because the results of their study sounds so promising, centres having access to glass yttrium-90 (90y) microspheres may want to try their methods. It is therefore necessary to clarify some of the points mentioned in their report.

关键词： yttrium Comments on