检索结果-南通市图书馆

Leaf morphogenesis:The multifaceted roles of mechanics

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2022年第7期15卷 1098-1119页

作者： Kexin Guo Changjin huang Yansong Miao Daniel j.Cosgrove K.jimmy hsia School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore School of Biological Sciences Nanyang Technological UniversitySingapore 637551Singapore Department of Biology The Pennsylvania State UniversityUniversity ParkPA 16802USA School of Chemical and Biomedical Engineering Nanyang Technological UniversitySingapore 637459Singapore

Plants produce a rich diversity of biological forms,and the diversity of leaves is especially *** of leaf morphogenesis have been studied in the past two decades,with a growing focus on the interactive roles of mechanics in recent *** of plant organs involves feedback by mechanical stress:growth induces stress,and stress affects growth and *** much attention has been given to potential stress-sensing mechanisms and cellular responses,the mechanical principles guiding morphogenesis have not been well *** we synthesize the overarching roles of mechanics and mechanical stress in multilevel and multiple stages of leaf morphogenesis,encompassing leaf primordium initiation,phyllotaxis and venation patterning,and the establishment of complex mature leaf ***,the roles of mechanics at multiscale levels,from subcellular cytoskeletal molecules to single cells to tissues at the organ scale,are *** highlighting the role of mechanical buckling in the formation of three-dimensional leaf shapes,this review integrates the perspectives of mechanics and biology to provide broader insights into the mechanobiology of leaf morphogenesis.

关键词： leaf morphogenesis cell-wall mechanics phyllotaxis and venation patterning differential and anisotropic growth mechanical buckling

Crystal structures of ligand binding region of uPARAP, a member of mannose receptor family

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Crystal structures of ligand binding region of uPARAP, a mem...

第五届中国结构生物学学术讨论会

作者： Cai Yuan henrik j.jürgensen Lars h.Engelholm Rui Li Min Liu Longguang jiang Zhipu Luo Niels Behrendt Mingdong huang Fuzhou University Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Finsen Laboratory Rigshospitalet/Biotech Research and Innovation Center (BRIC)

The mannose receptor family share a common domain organization and broad range of biological functions. u PARAP(or endo180) is a member of mannose receptor family and plays an important role in extracellular matrix remodeling through its interactions with its ligands, including collagens and u PAR. We report here the crystal structures of the u PARAP-LBR(Ligand Binding Region), which contains cysteine-rich domain(CysR), fibronectin type-II domain(FnII), C-type lectin-like domain(CTLD) 1 and 2, at ph 7.4 in both Ca2+-bound and Ca2+-free forms. The overall structures of the two u PARAP-LBR structures remain largely the same with FnII and CTLD1 forming a rigid core. however, the CysR and CTLD2 undergo slight shifts at different conditions. The CysR domain folds into a new and unique conformation different than the β-trefoil fold of typical CysR domain. The so-called long loop regions of CTLD1/2 mediate the direct contacts between CTLD1 and CTLD2. The long loop regions undergo a Ca2+ dependent conformational change, and is the key structural element affecting the overall conformation of u PARAP. Our results provide molecular mechanism to support the structural flexibility on u PARAP, and may shed light on the understanding of structural flexibility of other members of mannose receptor family.

关键词：

Partial oxidative gasification of model compound of biomass for hydrogen production in supercritical water fluidized bed reactor

在线全文

cnki会议

学校读者我要写书评

暂无评论

Partial oxidative gasification of model compound of biomass ...

第九届全国氢能学术会议

作者： h.jin,Y.j.Lu,L.j.Guo,C.Q.Cao,X.M.Zhang Xi''an jiaotong University,China

＜正＞Supercritical water can dissolve most organic substances and gases and has low viscosity, high density and strong transport ability,and high-moisture raw-biomass can be directly gasified to produce hydrogen in supercritical *** production from biomass in supercritical water is a promising technology,and partial oxidation can accelerate the heating rate,decrease oil and coke,improve the gasification of biomass and increase the production of hydrogen and the gasification *** this work,the partial oxidative gasification

关键词：

Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/hO-1 pathway

在线全文

cnki会议

学校读者我要写书评

暂无评论

journal of Animal Science and Biotechnology 2021年第4期12卷 1451-1467页

作者： Caiyun huang Zijuan Fan Dandan han Lee j.johnston Xi Ma Fenglai Wang State Key Lab of Animal Nutrition College of Animal Science&TechnologyChina Agricultural UniversityBeijing 100193China Swine Nutrition and Production West Central Research and Outreach CenterUniversity of MinnesotaMorrisMNUSA Department of Internal Medicine/Department of Biochemistry University of Texas Southwestern Medical CenterDallasTXUSA

Background:Oxidative stress is a main cause of piglet gut damage and *** quinone(PQQ),is a novel redox cofactor with antioxidant ***,the effect and mechanism that PQQ supplementation decreases oxidative injury in weaned pigs is not ***,the aim of this study is to confirm the effect of PQQ on regulating redox status in weaned pigs and the mechanism for antioxidant function by porcine intestinal epithelial cell line(IPEC-j2)challenged with h_(2)O_(2).Results:Experiment 1,144 Duroc×Landrace×Yorkshire pigs(weaned at 28 d)were allocated to four groups:received a basal diet(control)and diets supplemented with 0.15%,0.30%and 0.45%PQQ,*** d 28,growth performance,diarrhea incidence and redox factors were *** 2,IPEC-j2 were treated with or without PQQ in the presence or absence of h_(2)O_(2)for indicated time *** 3,IPEC-j2 were transfected with or without Nrf2 siRNA,then treated according to Experiment *** cell viability,redox factors,protein of tight junctions and Nrf2 pathway were *** vivo,PQQ supplementation demonstrated dose-related improvements in average daily gain,and gain to feed ratio(Linear Phea incidence and MDA content in liver and jejunum,and increased concentration of SOD in liver;0.3%PQQ supplementation decreased ileal and liver MDA concentration;and 0.15%PQQ supplementation decreased ileal MDA concentration(Ph h_(2)O_(2),pre-treatment with PQQ increased cell viability,tight junction proteins expression including ZO-1,ZO-2,Occludin and Claudin-1;and decreased ROS concentration and level of Caspase-3(Phe ratio of Bcl-2 to Bax and protein expression of nuclear Nrf2,***,Nrf2 knockdown by transfection with Nrf2 siRNA largely abrogated the positive effects of PQQ pretreatment on h_(2)O_

关键词： h_(2)O_(2) IPEC-j2 Nrf2 Oxidative stress Pyrroloquinoline quinone Weaned pig

维普期刊数据库

步行6min负荷超声心动图预测结缔组织病患者远期显性肺高血压

在线全文

学校读者我要写书评

暂无评论

中华高血压杂志 2015年第10期23卷 987-988页

作者： Kusunose K Yamada h hotchi j Bando M Nishio S hirata Y Ise T Yamaguchi K Yagi S Soeki T Wakatsuki T Kishi j Sata M 曲浥晨机构不详

肺高血压是结缔组织病（connective tissue disease,CTD）的主要死因。运动负荷试验已用于筛查早期肺高血压[1],但由于缺乏相关证据,最新的指南已停止其作为发现肺高血压的方法。近期研究发现平均肺动脉压（mean pulmonary arterial pre... 详细信息

肺高血压是结缔组织病（connective tissue disease,CTD）的主要死因。运动负荷试验已用于筛查早期肺高血压[1],但由于缺乏相关证据,最新的指南已停止其作为发现肺高血压的方法。近期研究发现平均肺动脉压（mean pulmonary arterial pressure,mPAP）升高导致心输出量异常可用于评估肺高血压进展及肺功能分级[2]。该研究将步行6min后的超声心动图参数作为非侵入性负荷试验。

关键词：负荷超声心动图 in 运动负荷试验平均肺动脉压心输出量 connective 结缔组织病左心室射血分数肺功能分级肺毛细血管楔压

维普期刊数据库

An experimental research on coal gasification for hydrogen production in supercritical water

在线全文

学校读者我要写书评

暂无评论

An experimental research on coal gasification for hydrogen p...

第九届全国氢能学术会议

作者： Y.L.Li,L.j.Guo,X.M.Zhang,h.jin,Y.j.Lu Xi''an jiaotong University,China

＜正＞The main problem in hydrogen produciton from coal gasification in supercritical water is the stable and continuous operation of high concentration of coal *** work in this paper aims at hydrogen production by gasification of high concentration coal in supercritical *** experiment of gasification of high concentration coal in supercritical water was

关键词：

双门静脉期钆塞酸二钠增强肝脏MRI无创性诊断肝细胞肝癌的个体内比较

在线全文

cnki会议

学校读者我要写书评

暂无评论

国际医学放射学杂志 2021年第2期44卷 245-246页

作者： h.j.Kang j.M.Lee S.K.jeon S.jang S.Park I.joo 王璐娜

摘要目的比较钆塞酸二钠增强MRI (Gd-EOB-MRI)第一门静脉期(PVP1)和第二门静脉期(PVP2)对肝细胞肝癌(hCC)廓清、强化包膜的显示及对hCC诊断效能差异。方法

关键词：

Impacts of heat and cold on hospitalizations for schizophrenia in hefei,China:An assessment of disease burden

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Impacts of heat and cold on hospitalizations for schizophren...

安徽省2019年度流行病与卫生统计学学术年会

作者：潘如兵 Zhang X Gao j Yi W Wei Q Xu Z Duan j Bai L Cheng Q Zhang Y Su h 安徽医科大学公共卫生学院

BACKGROUND:Compared with risk data(e.g.,RR or OR),attributable fraction(AF)provides more information on the formulation of policies and measures in the field of public ***,to date,existing AF evidence is scarce for the relationship between temperature and the hospitalizations for ***:Our primary goal is to estimate the attributable burden of hospitalizations for SCZ related to cold and heat,***,to identify vulnerable populations due to heat and ***:Poisson generalized linear models combined with DLNMs were used to estimate the association between hospitalizations for SCZ and temperature from 2005 to *** minimum risk temperature(MRT) was used as a reference,to calculate the burden of disease caused by cold and ***:We found that the majority hospitalizations attributed to heat(70.9%).In different individual levels,men are more sensitive to heat exposure while women are more vulnerable to *** different age groups,the results showed that the attributable risk was slightly higher in the over-40 s than in the under-40 ***,under different marital conditions,it showed that the unmarried had a little higher attributional risk than the ***:We should pay attention to the impact of heat on hospitalizations for SCZ,especially in those over 40years old,men and *** research will provide a basis for policymakers to develop intervention strategies to minimize the impact of adverse temperatures on hospitalizations for SCZ,thereby reducing the burden of disease.

关键词：

微波消融治疗有/无超声检测的甲状腺乳头状微癌包膜侵犯：一项多中心前瞻性队列研究

在线全文

cnki会议

学校读者我要写书评

暂无评论

国际医学放射学杂志 2023年第4期 480-481页

作者： L.Zheng j.P.Dou Z.h.han F.Y.Liu j.Yu Z.G.Cheng 程宇

摘要微波消融术（MWA）在治疗局限于腺实质的甲状腺乳头状微癌（PTMC）方面取得了良好的效果。然而，关于MWA治疗PTMC合并超声（US）检测到包膜侵犯的结局研究

关键词：