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Evolution of hepatitis B management in kidney transplantation

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World journal of Gastroenterology 2014年第2期20卷 468-474页

作者： Desmond Y h Yap Tak mao Chan Division of Nephrology Department of MedicineQueen Mary Hospitalthe University of Hong Kong

Chronic hepatitis B virus(hBV)infection adversely influences the clinical outcomes of renal transplant recipients owing to increased hepatic *** of hBV infection in kidney transplant recipients presents a challenge to clinicians,especially in endemic *** precipitates renal allograft *** with lamivudine,the first oral nucleoside analogue available,resulted in effective viral suppression,reduced liver-related complications,and improved patient survival so that medium-term data showed comparable patient survival rates between hepatitis B surface antigen-positive and hBsAg-negative kidney transplant recipients in the era of effective antiviral *** has replaced lamivudine as first-line therapy for treatment-na?ve subjects in view of the propensity for drug resistance with the *** of hBV infection in kidney transplant patients needs to take into consideration the nephrotoxicity of nucleoside/tide analogues such as adefovir and *** of hBV-related complications in kidney transplant recipients starts much earlier prior to transplantation,with vaccination of patients with chronic kidney disease and donor-recipient matching with regard to hBV *** addition to anti-viral treatment,patients with chronic hBV infection must have regular surveillance for liver cancer and assessment for the development of cirrhosis.

关键词： hepatitis B Kidney transplantation

Stellar Dynamical Modeling—Counting Conserved Quantities

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Research in Astronomy and Astrophysics 2023年第5期23卷 198-212页

作者： Richard j.Long Shude mao Yougang Wang Department of Astronomy Tsinghua UniversityBeijing 100084China jodrell Bank Centre for Astrophysics Department of Physics and AstronomyThe University of ManchesterOxford RoadManchester M139PLUK National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China

Knowing the conserved quantities that a galaxy’s stellar orbits conform to is important in helping us understand the stellar distribution and structures within the *** integrals of motion and resonances are particularly important,non-isolating integrals less *** compare the behavior and results of two methods for counting the number of conserved quantities,one based on the correlation integral approach and the other a more recent method using machine *** methods use stellar orbit trajectories in phase space as their only input,and we create such trajectories from theoretical spherical,axisymmetric,and triaxial model *** orbits have known isolating integrals and *** find that neither method is fully effective in recovering the numbers of these quantities,nor in determining the number of non-isolating *** a computer performance perspective,we find the correlation integral approach to be the *** the algebraic formulae of(multiple)conserved quantities from the trajectories has not been possible due to the lack of an appropriate symbolic regression *** the shortcomings we have noted,it may be that the methods are usable as part of a trajectory analysis tool kit.

关键词： galaxies kinematics and dynamics-methods numerical-galaxies structure

激光诱导荧光技术与地下水重金属原位检测应用进展

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岩矿测试 2025年第1期44卷 19-34页

作者：毛康薛家奇陈卓张华中国科学院地球化学研究所环境地球化学国家重点实验室贵州贵阳550081

对地下水重金属污染进行现场检测,是快速识别重金属种类和评价污染程度的重要手段。激光诱导荧光技术(LIF)利用特定荧光探针,在目标重金属存在下,通过激光诱导荧光探针产生/猝灭荧光,从而完成对重金属的识别和检测,具有快速甄别地下水... 详细信息

对地下水重金属污染进行现场检测,是快速识别重金属种类和评价污染程度的重要手段。激光诱导荧光技术(LIF)利用特定荧光探针,在目标重金属存在下,通过激光诱导荧光探针产生/猝灭荧光,从而完成对重金属的识别和检测,具有快速甄别地下水重金属污染特性和无损获取其价态的优势。本文在简述LIF检测重金属原理和LIF原位检测地下水重金属装备基础上,重点从荧光探针合成及其在重金属传感检测方法的构建上总结了基于不同荧光探针的LIF现场检测重金属的研究进展。目前可用于重金属检测的荧光探针包括以小分子探针、有机大分子和聚集诱导发光为主的有机荧光探针和以金纳米簇、量子点和金属有机框架材料为代表的纳米荧光探针。这些探针的合成及其对应的传感检测方法的构建表明LIF技术在地下水重金属检测中具有巨大优势。而针对地下水重金属检测的LIF设备研发方面的成果虽不如荧光传感检测方法丰富,但已研制出部分重金属的传感器和检测装备,表现出良好的应用前景。未来研究将会聚焦在地下水重金属主控因子识别和抗干扰技术研发、荧光探针合成与LIF检测方法构建、重金属传感部件和检测装备集成研制,以及检测技术标准化,为后续场地地下水典型重金属LIF检测技术的研究提供参考。

关键词：地下水重金属激光诱导荧光荧光探针现场检测

Differential introgression suggests candidate beneficial and barrier loci between two parapatric subspecies of Pearson＇s horseshoe bat Rhinolophus pearsoni

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Current Zoology 2016年第4期62卷 405-412页

作者： Xiuguang mao Shuyi ZhANG Stephen j. ROSSlTER Institute of Estuarine and Coastal Research East China Normal University Shanghai 200062 China School of Biological and Chemical Sciences Queen Mary University of London London E14NS UK

Observations that rates of introgression between taxa can vary across loci are increasingly common. here, we test for differential locus-wise introgression in 2 parapatric subspecies of Pearson＇s horseshoe bat （Rhinolophus pearsoni chinensis and R. p. pearsoni）. To efficiently identify putative speciation genes and/or beneficial genes in our current system, we used a candidate gene approach by including loci from X chromosome that are suggested to be more likely involved in reproductive isolation in other organisms and loci underlying hearing that have been suggested to spread across the hybrid zone in another congeneric species. Phylogenetic and coalescent analyses were performed at 2 X-linked, 4 hearing genes, as well as 2 other autosomal loci individually. Likelihood ratio tests could not reject the model of zero gene flow at 2 X-linked and 2 autosomal genes. In contrast, gene flow was supported at 3 of 4 hearing genes. While this introgression could be adaptive, we cannot rule out stochastic processes. Our results highlight the utility of the candidate gene approach in searching for speciation genes and/or beneficial genes across the species boundary in natural populations.

关键词： gene flow hybridization hybrid zone reproductive isolation.

农村基层治理法治化问题的解决路径——人民调解制度

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云南农业大学学报（社会科学版） 2025年第1期19卷 69-75页

作者：毛羿中贵州师范大学法学院贵州贵阳550001

基于国家所提出的在法治轨道上实现国家治理能力现代化的宏大命题,本文聚焦于在农村基层治理体系现代化的进程中,推进治理体系和方式法治化这一过程中所遇到的实际问题,通过研究我国农村的乡土化社会环境以及广阔的国土面积带来的地理... 详细信息

基于国家所提出的在法治轨道上实现国家治理能力现代化的宏大命题,本文聚焦于在农村基层治理体系现代化的进程中,推进治理体系和方式法治化这一过程中所遇到的实际问题,通过研究我国农村的乡土化社会环境以及广阔的国土面积带来的地理差异、文化差异以及民族差异,并以农村基层法治化建设的现状为现实依据,展现农村基层法治化建设遭遇的现实阻力并剖析深层原因,再通过论述人民调解制度的制度渊源、作用机理,体现其针对性地解决农村基层法治化阻力的制度优势,映射出人民调解制度的制度功效和实践价值并提出关于人民调解的制度化完善建议,通过制度运行环节的优化和适用方式的改进,最大程度地利用人民调解制度的制度价值,助力农村基层的法治化建设;从长远看,期望能够有益于农村基层治理能力紧跟国家治理体系和治理能力现代化的全局进程,在基层群众法治意识建设和社会法治建设层面缩小城乡差距。

关键词：农村基层治理法治化手段人民调解制度制度优化建议

FEATURES　OF　ANNEALING　MICROSTRUCTURE　AND　TEXTURE　IN　Ti－25Al－10Nb－3V－1Mo　ShEET

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中国有色金属学会会刊：英文版 1996年第2期6卷 67-71页

作者： mao, WM Yu, YN Yang, h Song, B Zou, DX Wang, B UNIV SCI & TEChNOL BEIjING DEPT MAT SCI & ENGNBEIJING 100083PEOPLES R CHINA MINIST MET IND DEPT SUPERALLOYCENT IRON & STEEL RES INSTBEIJING 100081PEOPLES R CHINA

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ＦＥＡＴＵＲＥＳＯＦＡＮＮＥＡＬＩＮＧＭＩＣＲＯＳＴＲＵＣＴＵＲＥＡＮＤＴＥＸＴＵＲＥＩＮＴｉ－２５Ａｌ－１０Ｎｂ－３Ｖ－１ＭｏＳＨＥＥＴＭａｏＷｅｉｍｉｎ；ＹｕＹｏｎｇｎｉｎｇ；ＹａｎｇＨｏｎｇ；ＳｏｎｇＢｏ（ＤｅｐａｒｔｍｅｎｔｏｆＭａｔｅｒｉａ...

关键词： Ti-25-A1-10Nb-3V-1Mo texture rolling deformation annealing

Simulation and evaluation study of atmospheric aerosol nonsphericity as a function of particle size

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Particuology 2024年第7期90卷 281-291页

作者： Qianjun mao Xin Nie School of Urban Construction Wuhan University of Science and TechnologyWuhan430065China College of New Energy and Materials Northeast Petroleum UniversityDaqing163318China

Aerosol nonsphericity causes great uncertainty in radiative forcing assessments and climate *** considerable studies have attempted to quantify this uncertainty,the relationship between aerosol nonsphericity and particle size is usually not considered,thus reducing the accuracy of the *** this study,a coupled inversion algorithm combining an improved stochastic particle swarm optimization algorithm and angular light scattering is used for the nonparametric estimation of aerosol nonsphericity variation with particle size,and the optimal sample selection method is employed to screen the *** on the verification of inversion accuracy,the variation of aerosol aspect ratio with particle size based on the ellipsoidal model in global regions has been obtained from Aerosol Robotic Network(AERONET)data,and the effect of nonsphericity on radiative forcing and dry deposition has been *** results show that the aspect ratio increases with particle size in all regions,with the maximum ranging from 1.4 to 1.8 in the desert,reflecting the differences in aerosol composition at different particle *** radiation calculations,considering aerosol nonsphericity makes the aerosol cooling effect weaker and surface radiative fluxes increase,but hardly changes the aerosol absorption,with maximum differences of 9.22%and 22.12%at the bottom and top of the atmosphere,***,the differences in radiative forcing between aspect ratios as a function of particle size and not varying with particle size are not significant,averaging less than 2%.Besides,the aspect ratio not varying with particle size underestimates the deposition velocity of small particles and overestimates that of large particles compared to that as a function of particle size,with maximum differences of 7%and 4%,respectively.

关键词： Aerosol nonsphericity Inversion Aspect ratio Radiative forcing Dry deposition velocity

周口市川汇区蔬菜种植产业现状及发展对策分析

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长江蔬菜 2025年第1期 1-4页

作者：毛喜平周口市川汇区蔬菜科学研究所河南周口466000

周口市川汇区蔬菜种植历史悠久,但近几年明显出现蔬菜种植产业生产滞后现象。通过深入调查走访,针对川汇区家庭小规模经营,种植人员老龄化日益严重,绿色理念、品牌意识淡薄,风险意识不强等问题,提出了几点对策,以期推动川汇区蔬菜种植... 详细信息

周口市川汇区蔬菜种植历史悠久,但近几年明显出现蔬菜种植产业生产滞后现象。通过深入调查走访,针对川汇区家庭小规模经营,种植人员老龄化日益严重,绿色理念、品牌意识淡薄,风险意识不强等问题,提出了几点对策,以期推动川汇区蔬菜种植产业发展再上新台阶。

关键词：蔬菜种植现状问题对策周口市川汇区

Astrophysical applications of gravitational microlensing

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Research in Astronomy and Astrophysics 2012年第8期12卷 947-972页

作者： Shude mao National Astronomical Observatories Beijing 100012 China

Since the first discovery of microlensing events nearly two decades ago, gravitational microlensing has accumulated tens of TBytes of data and developed into a powerful astrophysical technique with diverse applications. The review starts with a theoretical overview of the field and then proceeds to discuss the scientific highlights. （1） Microlensing observations toward the Magellanic Clouds rule out the Milky Way halo being dominated by MAssive Compact halo Objects （MAChOs）. This confirms most dark matter is non-baryonic, consistent with other observations. （2） Microlensing has discovered about 20 extrasolar planets （16 published）, including the first two jupiter-Saturn like systems and the only five ＂cold Neptunes＂ yet de- tected. They probe a different part of the parameter space and will likely provide the most stringent test of core accretion theory of planet formation. （3） Microlensing pro- vides a unique way to measure the mass of isolated stars, including brown dwarfs and normal stars. half a dozen or so stellar mass black hole candidates have also been pro- posed. （4） high-resolution, target-of-opportunity spectra of highly-magnified dwarf stars provide intriguing ＂age＂ determinations which may either hint at enhanced he- lium enrichment or unusual bulge formation theories. （5） Microlensing also measured limb-darkening profiles for close to ten giant stars, which challenges stellar atmo- sphere models. （6） Data from surveys also provide strong constraints on the geometry and kinematics of the Milky Way bar （through proper motions）; the latter indicates predictions from current models appear to be too anisotropic compared with observa- tions. The future of microlensing is bright given the new capabilities of current surveys and forthcoming new telescope networks from the ground and from space. Some open issues in the field are identified and briefly discussed.

关键词： Galaxy: structure -- formation -- bulge -- gravitational lensing --planetary systems: formation