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NADPH Thioredoxin Reductase C Is Involved in Redox Regulation of the Mg-Chelatase I Subunit in Arabidopsis thaliana Chloroplasts

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Molecular Plant 2014年第7期7卷 1252-1255页

作者： juan Manuel Pérez-Ruiz Manuel guinea Leonor Puerto-galán francisco javier Cejudo Instituto de Bioquímica Vegetal y fotosíntesis Universidad de Sevilla-Consejo Superior de Investigaciones Científicas 41092-Sevilla Spain Umea Plant Science Centre Department of Plant Physiology Umea University S-901 87 Umea Sweden

Dear Editor, The synthesis of tetrapyrroles, including chlorophylls, is central for chloroplast function. The metabolic pathway of tetrapyrrole biosynthesis in Arabidopsis is initiated with the formation of amino levulinic acid （ALA）, which is con- verted by a series of common reactions to protoporphy- tin IX （Proto IX）（Tanaka et al., 2011）. Then the pathway diverges into two branches： the synthesis of heme/bilin and chlorophylls. The insertion of Mg2＋ into Proto IX, cata- lyzed by Mg-chelatase, is the first committed reaction of the chlorophyll branch and is considered a key step for the regulation of the whole pathway. Mg-chelatase is a het- erotrimeric enzyme composed of subunits CHLI, CHLD, and CHLH, the reaction mechanism of which has been estab- lished. It is a two-step process consisting in the Mg-ATP- dependent activation of the enzyme, which implies the formation of a ternary complex of subunits CHLI and CHLD with ATP-Mg2＋, and Mg2＋ chelation, which is catalyzed by CHLH driven by ATP hydrolysis, CHLI providing ATPase activity to the complex （Tanaka et al., 2011）. In Arabidopsis, CHLH and CHLD are encoded by single genes, whereas two genes, CHLI-I and CHLI-2, encode the two isoforms of CHLI.

关键词： synthesis of tetrapyrroles chlorophylls Arabidopsis

A Study of Climate Variability in Papua New guinea

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journal of Geoscience and Environment Protection 2019年第5期7卷 45-52页

作者： f. B. Pereira O. Renagi j. j. Panakal G. Anduwan Department of Applied Physics PNG University of Technology Lae Papua New Guinea

This Papua New guinea is nearly tropical and we get rain in almost all seasons. But over the past few decades, it was observed that climate is changing considerably. Changes in solar influx, frequent volcanic eruptions and greenhouse gas emissions aggravate this effect. In this scenario, climate variability in Papua New guinea has been studied using atmospheric parameters like atmospheric temperature and rainfall published by Bureau of Meteorology, Australia for the period 1996-2018. In order to improve the forecast of climate variability, the data has been analyzed using wavelet methods. An increasing trend of atmospheric temperature and rainfall are observed with a yearly periodicity except 2007-2009. The night-time atmospheric temperature showed quasi-periodic variations of two-to-four years. These variations will be discussed in terms of the SOI variations, volcanic eruptions and increase in greenhouse gas emissions.

关键词： Climate Atmospheric Temperature Rainfall Greenhouse gas

Anti-ulcer potentials of phylum mollusca(tropical snail)slime

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Asian Pacific journal of Tropical Medicine 2009年第3期2卷 23-28页

作者： Nwodo Nj Okonta j M Ezugwu CO Attama AA faculty of Pharmaceutical Sciences University of NigeriaNsukka410001Enugu State

Objective:The effectiveness of the slimy substance in snail to regenerate and repair damaged areas on it body/shell lead to this ***:The anti-ulcer’property of snail slime extracted from phylur mollusca(tropical snail) from the giant African snail Archachatina marginata(***) was investi gated using histamine,stress and indomethacin-induced *** solubility profile of extract was investiga ted in different solvents and at different *** analysis was carried out to determine the type of constituents present in the slim,while acute toxicity test was carried out to evaluate its profile of toxicity The effect of the snail slim on gastrointestinal motility was investigated in mice,while the guinea pig ileum wa used to study the effect of the extract on contraction produced by acetylcholine and *** snail slim contained copious quantity of protein,with varying amounts of simple sugars,carbohydrates and *** slime was not soluble in most common solvents and increases in temperature,did not appear to increase its sol ***:The result further indicated that although the snail slime exhibited significant(Pgainst ulcer induced by *** snai slime potently inhibited gastrointestinal movement in mice in a dose-dependent manner;however,it was not a ble to inhibit contraction induced by acetylcholine and histamine in guinea pig ***:The snai mucin possesses potent antiulcer properties without any toxic *** mechanism responsible for the anti-ul cer property may not be postulated with certainty but cytoprotective and anti-spasmodic activities are most likel to be involved.

关键词： Anti-ulcer activity Phylum moliusca Snail slime

Petrographic composition of coal within the Benue Trough,Nigeria and a consideration of the paleodepositional setting

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International journal of Coal Science & Technology 2022年第3期9卷 67-90页

作者： A.D.Mangs N.j.Wagner O.M.Moroeng U.A.Lar DSI-NRf CIMERA Department of GeologyUniversity of JohannesburgJohannesburgSouth Africa Department of Geology University of JosJosNigeria

The petrographic composition of Cretaceous-age coals hosted in the Benue Trough,Nigeria is presented and discussed in terms of the paleodepositional settings that infuenced the coal-bearing *** Benue Trough is a failed arm of the triple junction of an inland sedimentary basin that extends in a NE-SW direction from the Gulf of guinea in the south,to the Chad Basin in the north.A total of twenty-nine(29)coal samples were obtained from nineteen coal localities in the Upper(UBT),Middle(MBT),and Lower Benue Trough(LBT).The high average volatile matter yield,low average ash yield,high calorifc value(24.82 Mj/kg,on average),and low sulphur values indicate good quality coal *** organic matter is dominated by vitrinite,reported at an average of 59.3%by volume(mineral-matter free).Variation was noted in the inertinite content across three *** macerals were not commonly observed in the studied samples and were absent in the MBT *** facies studies decipher the paleoenvironmental conditions under which the vegetation *** commonly used are the gelifcation index(GI),tissue preservation index(TPI),ground water index(GWI and variations),vegetation index(VI),and wood index(WI).Comparing the array of coal facies models applied,the MBT samples difer from the UBT and LBT samples,concurring with the coal quality *** UBT and LBT coals formed in an upper deltaic to drier piedmont plane depositional environment,while the MBT coal formed in a lower deltaic marsh to wet forest swamp depositional *** samples indicate an ombrotrophic *** view of the modifed equations and the plots used,interpreting depositional environments from just a single model is not reliable.

关键词： Benue Trough Coal petrography Depositional environment Microlithotypes Vitrinite

Genetic regulators of cytokine responses upon BCG vaccination in children from West Africa

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journal of Genetics and Genomics 2023年第6期50卷 434-446页

作者： Collins K.Boahen S.j.C.f.M.Moorlag Kristoffer jarlov jensen Vasiliki Matzaraki Stephanie fanucchi Ivan Monteiro Charlotte de Bree Ezio T.fok Musa Mhlanga Leo A.B.joosten Peter Aaby Christine Stabell Benn Mihai G.Netea Vinod Kumar Department of Internal Medicine and Radboud Institute of Molecular Life Sciences(RIMLS) Radboud University Medical CenterNjmegen6525 HPthe Netherlands Department of Internal Medicine and Radboud Center for Infectious Diseases(RCI) Radboud University Medical CenterNjmegen6525 HPthe Netherlands Odense Patient Data Explorative Network University of Southern Denmark/Odense University HospitalOdenseDK-5000Denmark Center for Clinical Research and Prevention Frederiksberg and Bispebjerg HospitalDK-2000FrederiksbergDenmark Lemba Therapeutics Nijmegen6525 GAthe Netherlands Bandim Health Project Indepth NetworkBissaucodex 1004Guinea-Bissau Epigenomics&Single Cell Biophysics Group Department of Cell Biology FNWIRadboud Institute for Molecular Life Sciences(RIMLS)Njmegen6525 HPtheNetherlands Department of Human Genetics Radboud University Medical Center6525 HPthe Netherlands Bandim Health Project Statens Serum InstitutCopenhagen SDK-2300Denmark Danish Institute for Advanced Study University of Southern DenmarkOdenseDK-5000Denmark Department of Internal Medicine and Radboud Center for Infectious Diseases Radboud University Medical CenterNijmegen6525 HPthe Netherlands Department for Immunology and Metabolism Life and Medical Sciences Institute(LIMES)University of BonnGermany University of Groningen University Medical Center GroningenDepartment of GeneticsGroningen970o0 RBthe Netherlands Nitte(Deemed to be University) Nitte University Centre for Science Education and Research(NUCSER)Medical Sciences ComplexDeralakatteMangalore575018India

Genetic variation is a key factor influencing cytokine production capacity,but which genetic loci regulate cytokine production before and after vaccination,particularly in African population is ***,we aimed to identify single-nucleotide polymorphisms(SNPs)controlling cytokine responses after microbial stimulation in infants of West-African ancestry,comprising of low-birth-weight neonates randomized to bacillus Calmette-Gue rin(BCG)vaccine-at-birth or to the usual delayed ***-wide cytokine cytokine quantitative trait loci(cQTL)mapping revealed 12 independent loci,of which the LINC01082-LINC00917 locus influenced more than half of the cytokine-stimulation pairs ***,nine distinct cQTLs were found among infants randomized to *** validation confirmed that several complement genes affect cytokine response after BCG *** observed a limited overlap of common cQTLs between the West-African infants and cohorts of Western European *** data reveal strong population-specific genetic effects on cytokine production and may indicate new opportunities for therapeutic intervention and vaccine development in African populations.

关键词： Cytokines Geneticvariation West Africa Immunogenomics QTL BCG

巴布亚新几内亚合恩半岛晚第四纪上升珊瑚礁造礁珊瑚的成岩历史

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沉积学报 1992年第1期10卷 133-145页

作者：祝仲蓉 j.Chappell j.Marshall 澳大利亚国立大学生物地理及地貌系澳大利亚矿物资源局

更新世以来,剧烈的构造运动已将巴布亚新几内亚合恩半岛东北海岸的晚第四纪珊瑚礁阶地抬升上千米.阶地中造礁珊瑚的成岩变化和成岩产物的组构特征反映了该礁的成岩历史,充分体现该区快速构造上升的影响.海水潜流带和淡水渗流带为上升礁... 详细信息

更新世以来,剧烈的构造运动已将巴布亚新几内亚合恩半岛东北海岸的晚第四纪珊瑚礁阶地抬升上千米.阶地中造礁珊瑚的成岩变化和成岩产物的组构特征反映了该礁的成岩历史,充分体现该区快速构造上升的影响.海水潜流带和淡水渗流带为上升礁的主要成岩环境.生物钻孔、生物碎屑填隙、珊瑚文石针粗化、珊瑚骨骼的溶解和新生变形转化,以及其不同矿物成分和组构的种种胶结物的胶结作用是造礁珊瑚经历的主要成岩作用.地球化学资料表明其成岩变化发生于开放的化学体系之中.

关键词：造礁珊瑚成岩作用第四纪

Keeping an ear out:size relationship of the tympanic bullae and pinnae in bandicoots and bilbies(Marsupialia:Peramelemorphia)

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Current Zoology 2022年第3期68卷 251-264页

作者： Melissa C.TAYLOR Kenny j.TRAVOUILLON Margaret E.ANDREW Patricia A.fLEMING Natalie M.WARBURTON Terrestrial Ecosystem Science and Sustainability Harry Butler InstituteMurdoch University90 South StMurdochWA 6150Australia Collections and Research Western Australian MuseumWelshpoolWA 6106Australia

Bandicoots and bilbies(Order Peramelemorphia)occupy a broad range of habitats across Australia and New guinea,from open,arid deserts to dense *** once diverse group has been particularly vulnerable to habitat loss and introduced eutherian predators,and numerous species extinctions and range retractions have *** reasons for this loss requires greater understanding of their *** of the pinnae and tympanic bullae varies markedly among *** hearing is important for both predator avoidance and prey location,the variability in ear morphology could reflect specialization and adaptation to specific environments,and therefore be of conservation *** measured 798 museum specimens representing 29 species of *** for phylogenetic relatedness and head length,pinna surface area was weakly negatively correlated with average precipitation(rainfall being our surrogate measure of vegetation productivity/complexity),and there were no environmental correlates with effective diameter(pinna width).Controlling for phylogenetic relatedness and skull length,tympanic bulla volume was negatively correlated with *** that inhabited drier habitats,which would be open and allow sound to carry further with less obstruction,had relatively larger pinnae and tympanic *** contrast,species from higher rainfall habitats,where sounds would be attenuated and diffused by dense vegetation,had the smallest pinnae and bullae,suggesting that low-frequency hearing is not as important in these *** with temperature did not reach statistical *** findings highlight linkages between hearing traits and habitat that can inform conservation and management strategies for threatened species.

关键词： external ear hearing ecology marsupial middle ear sound perception

构造运动对生物礁成岩作用的影响——以巴布亚新几内亚合恩晚第四纪珊瑚礁研究为例

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海洋地质与第四纪地质 1990年第2期10卷 91-101页

作者：祝仲蓉 j.夏培尔 j.马歇尔澳大利亚国立大学澳大利亚矿物资源局

对地处新构造运动强烈地区的合恩晚第四纪上升珊瑚阶地三条剖面的样品分析表明:造礁珊瑚和礁灰岩的不稳定矿物成分的转化和成岩强度与构造运动密切相关,而局部气候状况似乎不起主导作用。上升速率较低地区的珊瑚骨骼和礁灰岩的方解石化... 详细信息

对地处新构造运动强烈地区的合恩晚第四纪上升珊瑚阶地三条剖面的样品分析表明:造礁珊瑚和礁灰岩的不稳定矿物成分的转化和成岩强度与构造运动密切相关,而局部气候状况似乎不起主导作用。上升速率较低地区的珊瑚骨骼和礁灰岩的方解石化普遍、彻底,孔隙中方解石胶结物含量大仅存文石胶结物残余;与之相反,构造上升速率高的地区虽有较高的年降雨量,但珊瑚和礁灰岩转化不普遍,方解石胶结物含量低且保存大量文石胶结物。这是因为构造上升决定了阶地的区域地貌特征,影响阶地地形起伏,从而控制了在生物礁成岩变化中起主要作用的水动态条件。

关键词：构造运动生物礁成岩作用珊瑚礁

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氧化石墨烯薄膜首次实现有机分子筛分

高分子通报 2018年第1期 2-2页

作者：赵宁钱振超 Yang Q Su Y Chi C Cherian C T Huang K Kravets V G Wang f C Zhang j C Pratt A Grigorenko A N guinea f Geim A K Nair R R

氧化石墨烯簿膜作为快速渗透分子筛的研究受到广泛关注,但其仅对水溶液能够有效筛分,对有机溶剂不具有渗透性,这一现象还未能得到深入理解。来自曼彻斯特大学的Su和Nair等利用大尺寸氧化石墨烯片（10μm20μm）构筑氧化石墨烯超薄膜,厚... 详细信息

氧化石墨烯簿膜作为快速渗透分子筛的研究受到广泛关注,但其仅对水溶液能够有效筛分,对有机溶剂不具有渗透性,这一现象还未能得到深入理解。来自曼彻斯特大学的Su和Nair等利用大尺寸氧化石墨烯片（10μm20μm）构筑氧化石墨烯超薄膜,厚度仅为10nm。该超薄膜中包含平滑的二维毛细管和宽度仅为1nm的小孔,可将99.9%以上的有机染料从甲

关键词：氧化石墨烯有机分子筛超薄膜