检索结果-南通市图书馆

世界核心医学期刊文摘（胃肠病学分册） 2005年第4期1卷 16-17页

作者： Moore H.g. Shoup M. Riedel E. j.g.guillem 李康 1275 York Avenue New York NY 10021 United StatesDr.

PURPOSE: This study was designed to identify preoperative and intraoperative features of locally recurrent colorectal cancer that predict R0 resection in patients scheduled for attempted complete resection followed by intraoperative radiation therapy. METHODS: Review of a prospective data base identified 119 patients brought to the intraoperative radiation therapy suite for planned complete resection of locally recurrent rectal (n=101) and colon (n=18) cancer between january 1994 and November 2000. R0 resection was achieved in 61 patients. This group was compared with patients in which an R1 (n=38), R2 (n=7), or palliative procedure (n=13) was performed. Variables evaluated included: tumor location, features of the primary tumor, and preoperative findings on computed tomography , magnetic resonance imaging, and history/physical. Tumor location was establish ed by review of operative/pathologic reports and classified as axial (anastomoti c/perineal), anterior (bladder/genitourinary organs), posterior (presacral), or lateral (pelvic sidewall). RESULTS: When recurrence was confined to the axial location only, or axial and anterior locations, R0 resection was achieved signific antly more often than when other locations were involved (P gnificantly less often than when there was no lateral component (P = 0.002). For patients with available preoperative computed tomography and/or magnetic reson ance imaging results (n = 70), the finding of lateral tumor involvement was asso ciated with R0 resection significantly less often than when lateral disease was not identified (P = 0.004). CONCLUSIONS: Pelvic recurrences confined to the axial location, or axial and anterior locations, are more likely to be completely re sectable (R0) than those involving the pelvic sidewall. Efforts to enhance preop erative identification and imaging of these patients are clearly justified.

关键词：结直肠癌术中放疗结肠癌姑息手术肿瘤位置原发肿瘤后位患者术前诊断吻合口体格检查

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

NANOgrav hints on planet-mass primordial black holes

引用

Science China(Physics,Mechanics & Astronomy) 2022年第3期65卷 26-32页

作者： guillem Domenech Shi Pi INFN Sezione di Padova Padova 1-35131Italy CAS Key'Laboratory of Theoretical Physics.Institute of Theoretical Physics ChinesAcademy of SciencesBeijing 100190China Kavli Institute for the Physics and Mathematics of the Universe(WPI) The University of Tokyo Institutes for Advanced StudyThe University of TokyoKashiwaChiba 277-8583Japan

Recently, the North American Nanohertz Observatory for gravitational Waves(NANOgrav) claimed the detection of a stochastic common-spectrum process of the pulsar timing array(PTA) time residuals from their 12.5 year data, which might be the first detection of the stochastic background of gravitational waves(gWs). We show that the amplitude and the power index of such waves imply that they could be the secondary gWs induced by the peaked curvature perturbation with a dust-like post inflationary era with-0.091 ≤ w ≤ 0.048. Such stochastic background of gWs naturally predicts substantial existence of planet-mass primordial black holes(PBHs), which can be the lensing objects for the ultrashort-timescale microlensing events observed by the Optical gravitational Lensing Experiment(OgLE).

关键词： pulsar timing array stochastic gravitational waves the early universe

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Morphological determinants of jumping performance in the Iberian green frog

引用

Current Zoology 2020年第4期66卷 417-424页

作者： gregorio Moreno-Rueda Abelardo Requeinia-Blaimco Francisco j.Zamora-Camacho Mar Comas guillem Pascual Departamento de Zoologia Facultad de CienciasUniversidad de GranadaGranadaE-18071Spain Department of Biological Sciences Dartmouth CollegeHanoverNH03055USA galanthus/Ctra.de juia 46.17460 CelraSpain

Predation is one of the main selective forces in nature, frequently selecting potential prey for developing escape strategies. Escape ability is typically influenced by several morphological parameters, such as morphology of the locomotor appendices, muscular capacity, body mass, or fluctuating asymmetry, and may differ between sexes and age classes. In this study, we tested the relationship among these variables and jumping performance in 712 Iberian green frogs Pelophylax perezi from an urban population. The results suggest that the main determinant of jumping capacity was body size (explaining 48% of variance). Larger frogs jumped farther, but jumping performance reached an asymptote for the largest frogs. Once controlled by structural body size, the heaviest frogs jumped shorter distances, suggesting a trade-off between fat storage and jumping performance. Relative hind limb length also determined a small but significant percentage of variance (2.4%) in jumping performance-that is, the longer the hind limbs, the greater the jumping capacity. juveniles had relatively shorter and less muscular hind limbs than adults (for a given body size), and their jumping performance was poorer. In our study population, the hind limbs of the frogs were very symmetrical, and we found no effect of fluctuating asymmetry on jumping performance. Therefore, our study provides evidence that jumping performance in frogs is not only affected by body size, but also by body mass and hind limb length, and differ between age classes.

关键词： body mass fluctuating asymmetry hind limb length hind limb width locomotor performance morphometry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stepping up after spinal cord injury:negotiating an obstacle during walking

引用

Neural Regeneration Research 2025年第7期20卷 1919-1929页

作者： Alain Frigon Charly g.Lecomte Department of Pharmacology-Physiology Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate *** spinal cord injury,stepping over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including the parietal cortex,premotor cortex,and motor *** information and planning are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiology obstacle negotiation spinal cord injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mapping the technology footprint in design for social innovation

引用

International journal of Innovation Studies 2022年第3期6卷 216-227页

作者： Chuan Li guillem Bacete Research Unit for Economics of Culture and Tourism Applied Economics DepartmentUniversity of ValenciaValencia46010Spain

Technology and design are increasingly recognized as important drivers of social innovation(SI).While new-age technologies can disrupt the realm of social innovation through resource-efficient solutions and multiple outcome benefits,the appliction of design thinking approaches and techniques can enhance the potential for SI through humancentered participatory processes and a socially shared vision and *** extensive research focusing on SI practices driven by technology and design respectively,few studies have concentrated on the synergistic effects of technology and design in the field of *** paper addresses this gap through an exploratory study on the incorporation and role of technology in the practice of design for *** applying the mapping approach to a sample of 81 Design-enabled Innovation(DEI)pilot projects in the DESIgNSCAPES project,the distribution,hosts and manifestations of technology footprints are identified,taking into account the multi-phase innovation processes and multifaceted role of *** findings suggest that in design-supported SI,technology can be integrated in a systematic and conventional manner across a range of domains related to people,interactions,contexts,and artefacts and that its interaction with design actions is highly dependent on the different roles of design,followed by a further discussion of a conceptual argument regarding the possible role of technology in supporting design for *** on these findings and results,the article concludes with the limitations of the study and possible theoretical and managerial implications.

关键词： Social innovation Technologyfootprint Design-enabled innovation Design approach Designforsocial innovation Mapping approach

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioelectronic medicine in modulation of cortical spreading depolarization and beyond

引用

Neural Regeneration Research 2025年第2期20卷 481-482页

作者： Khaled Alok Timothy g.White Chunyan Li Department of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/NorthwellHempsteadNYUSA Translational Brain Research Laboratory The Feinstein Institutes for Medical ResearchManhassetNYUSA

Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurological *** pharmacological interventions have demonstrated initial potential in addressing CSDs,a standardized treatment approach has not yet been *** objective of this perspective is to explore emerging bioelectronic methodologies for addressing CSDs,particularly emphasizing TNS,and to underscore TNS’s capacity to enhance neurovascular coupling and cerebral perfusion.

关键词： cerebral perfusion electronic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Epistatic interactions between pterin and carotenoid genes modulate intra-morph color variation in a lizard

引用

Integrative Zoology 2022年第1期17卷 44-53页

作者： Prem AgUILAR Pedro ANDRADE guillem PÉREZ I DE LANUZA CIBIO/InBIO Centro de Investigação em Biodiversidade e Recursos Genéticos da Universidade do PortoPortoPortugal Ethology Lab Institut Cavanilles de Biodiversitat i Biologia EvolutivaUniversitat de ValènciaValènciaSpain

Color polymorphisms have become a major topic in evolutionary biology and substantial efforts have been devoted to the understanding of the mechanisms responsible for originating such colorful ***-morph continuous variation,on the other hand,has been neglected in most of the ***,we combine spectrophotometric/visual modeling and genetic data to study the mechanisms promoting continuous variation within categorical color morphs of Podarcis *** results suggest that intra-morph variability in the pterin-based orange morph is greater compared to white and yellow *** also show that continuous variation within the orange morph is partially discriminable by *** results indicate that allelic variants at the BCO2 locus(responsible for deposition of yellow carotenoids)contribute to generate continuous variation in orange ***,other intrinsic and/or extrinsic mechanisms,such as body size,might be involved,opening a new avenue for future research on the drivers of continuous variation within-morphs.

关键词： BCO2 color polymorphism continuous variation lizard Podarcis muralis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

引用

Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of Zika virus non-structural protein mutations on hippocampal damage

引用

Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.g.Cassiano Roney S.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNS)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging

引用

Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.gunn Laura Bennet Hamid Abbasi Mātai Medical Research Institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical Imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering Institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：