检索结果-南通市图书馆

Science china(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 58-63页

作者： Xiang-Qun Fu hong-Wei Li jian-hong Shi Tan Li Wan-Su Bao Henan Key Laboratory of Quantum Information and cryptography Information Engineering University Synergetic Innovation center of Quantum Information and Quantum Physics University of Science and Technology of China

With the development of quantum computing technology, quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key cryptography. This paper designs a quantum trapdoor one-way function via EPR pairs and quantum measurements. Based on this, a new quantum public-key cryptosystem is presented, which offers forward security,and can resist the chosen-plaintext attack and chosen-ciphertext attack. compared with the existing quantum public-key cryptos,eavesdropping can be automatically detected in this new quantum public-key cryptosystem under a necessary condition, which is also detailed in the paper.

关键词： quantum public-key crypto trapdoor one-way function EPR pairs

Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury:state of the art and future perspectives

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3151-3171页

作者： Fatima Aldali chunchu Deng Mingbo Nie hong chen Department of Rehabilitation Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Orthopedics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

“Peripheral nerve injury”refers to damage or trauma affecting nerves outside the brain and spinal *** nerve injury results in movements or sensation impairments,and represents a serious public health *** severed peripheral nerves have been effectively joined and various therapies have been offered,recovery of sensory or motor functions remains limited,and efficacious therapies for complete repair of a nerve injury remain *** emerging field of mesenchymal stem cells and their exosome-based therapies hold promise for enhancing nerve regeneration and *** stem cells,as large living cells responsive to the environment,secrete various factors and *** latter are nano-sized extracellular vesicles containing bioactive molecules such as proteins,microRNA,and messenger RNA derived from parent mesenchymal stem *** have pivotal roles in cell-to-cell communication and nervous tissue function,offering solutions to changes associated with cell-based *** ongoing investigations,mesenchymal stem cells and mesenchymal stem cell-derived exosome-based therapies are in the exploratory stage.A comprehensive review of the latest preclinical experiments and clinical trials is essential for deep understanding of therapeutic strategies and for facilitating clinical *** review initially explores current investigations of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in peripheral nerve injury,exploring the underlying ***,it provides an overview of the current status of mesenchymal stem cell and exosomebased therapies in clinical trials,followed by a comparative analysis of therapies utilizing mesenchymal stem cells and ***,the review addresses the limitations and challenges associated with use of mesenchymal stem cell-derived exosomes,offering potential solutions and guiding future directions.

关键词： clinical trials exosome extracellular vesicles mesenchymal stem cells nerve regeneration peripheral nerve injury pre-clinical experiments

维普期刊数据库

Sequence-activated chemiluminescence probes: programmable illumination for high-contrast in vivo sensing and imaging

在线全文

学校读者我要写书评

暂无评论

Science china chemistry 2025年第01期 26-34页

作者： Yutao Zhang juan Li Wei-hong Zhu Zhiqian Guo Shanghai Key Laboratory of Functional Materials chemistry Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology State Key Laboratory of Bioreactor Engineering Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell MetabolismEast China University of Science & Technology

Sequence-activated chemiluminescence(cL) technique offers a unique approach to detecting specific biomolecules or cellular events with high sensitivity and spatial resolution. The fundamental principle behind sequence-activated cL probes involves tailoring highly-controllable cL signals in response to specific sequences or events of interest, thus enabling high-contrast signals under complex physiological conditions. This sequential activation could be triggered by enzymes, reactive oxygen species(ROS), biothiols or changes in the microenvironment. These unique sequence-activated cL probes bestow several advantages, including minimal background, deep-tissue penetration, and the ability of non-invasive or minimally invasive detection. The sequence-activated cL techniques represent a significant advancement in molecular imaging and diagnostics. In this mini-review, we focus on the latest developments in sequential cL probes, addressing the technical challenges and discussing the future trajectory by harnessing cL signaling and molecular recognition.

关键词：

同方期刊数据库

Tailoring Light–Matter Interactions in Overcoupled Resonator for Biomolecule Recognition and Detection

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 262-280页

作者： Dongxiao Li hong Zhou Zhihao Ren cheng Xu chengkuo Lee Department of Electrical and computer Engineering National University of SingaporeSingapore 117583Singapore center for Intelligent Sensors and MEMS(cISM) National University of SingaporeSingapore 117608Singapore

Plasmonic nanoantennas provide unique opportunities for precise control of light–matter coupling in surface-enhanced infrared absorption(SEIRA)spectroscopy,but most of the resonant systems realized so far suffer from the obstacles of low sensitivity,narrow bandwidth,and asymmetric Fano resonance ***,we demonstrated an overcoupled resonator with a high plasmon-molecule coupling coefficient(μ)(Oc-Hμresonator)by precisely controlling the radiation loss channel,the resonator-oscillator coupling channel,and the frequency detuning *** observed a strong dependence of the sensing performance on the coupling state,and demonstrated that Oc-Hμresonator has excellent sensing properties of ultra-sensitive(7.25%nm^(−1)),ultra-broadband(3–10μm),and immune asymmetric Fano *** characteristics represent a breakthrough in SEIRA technology and lay the foundation for specific recognition of biomolecules,trace detection,and protein secondary structure analysis using a single array(array size is 100×100μm^(2)).In addition,with the assistance of machine learning,mixture classification,concentration prediction and spectral reconstruction were achieved with the highest accuracy of 100%.Finally,we demonstrated the potential of Oc-Hμresonator for SARS-coV-2 *** findings will promote the wider application of SEIRA technology,while providing new ideas for other enhanced spectroscopy technologies,quantum photonics and studying light–matter interactions.

关键词： Plasmonic nanoantennas Light-matter interaction Surface-enhanced infrared absorption Overcoupled Biosensing

维普期刊数据库

Deciphering Water Oxidation catalysts: The Dominant Role of Surface chemistry over Reconstruction Degree in Activity Promotion

在线全文

学校读者我要写书评

暂无评论

NANO-MIcRO LETTERS 2025年第1期17卷 1-15页

作者： An, Li Li, jianyi Sun, Yuanmiao Zhu, jiamin Seow, justin Zhu Yeow Zhang, hong Zhang, Nan Xi, Pinxian Xu, Zhichuan j. Yan, chun-Hua Lanzhou Univ Frontiers Sci Ctr Rare Isotopes Key Lab Nonferrous Met Chem & Resources Utilizat G State Key Lab Appl Organ ChemColl Chem & Chem Eng Lanzhou 730000 Peoples R China Nanyang Technol Univ Sch Mat Sci & Engn Singapore 639798 Singapore chinese Acad Sci Fac Mat Sci & Energy Engn Shenzhen Inst Adv Technol Inst Technol Carbon Neutral Shenzhen 518055 Peoples R China Yunnan Univ Natl Ctr Int Res Photoelect & Energy Mat Electron Microscopy Ctr Sch Mat & EnergyKey Lab Electromagnet Mat & Devic Kunming 650091 Peoples R China Baotou Res Inst Rare Earths State Key Lab Baiyunobo Rare Earth Resource Res & Baotou 014030 Peoples R China Peking Univ Beijing Natl Lab Mol Sci State Key Lab Rare Earth Mat Chem & Applicat PKU HKU Joint Lab Rare Earth Mat & Bioinorgan Chem Beijing 100871 Peoples R China

Demonstrate that the key factor to determine the activity of reconstructed surfaces is the surface chemistry, instead of reconstruction degree using the popular perovskite LaNi1-xFexO3 oxides as model *** content can influence both the surface reconstruction degree, the activation degree, and the activity of reconstructed *** oxygen evolution reaction activity of reconstructed catalysts is primarily governed by the chemistry of the reconstructed surface species. Water splitting hinges crucially on the availability of electrocatalysts for the oxygen evolution reaction. The surface reconstruction has been widely observed in perovskite catalysts, and the reconstruction degree has been often correlated with the activity enhancement. Here, a systematic study on the roles of Fe substitution in activation of perovskite LaNiO3 is reported. The substituting Fe content influences both current change tendency and surface reconstruction degree. LaNi0.9Fe0.1O3 is found exhibiting a volcano-peak intrinsic activity in both pristine and reconstructed among all substituted perovskites in the LaNi1-xFexO3 (x = 0.00, 0.10, 0.25, 0.50, 0.75, 1.00) series. The reconstructed LaNi0.9Fe0.1O3 shows a higher intrinsic activity than most reported NiFe-based catalysts. Besides, density functional theory calculations reveal that Fe substitution can lower the O 2p level, which thus stabilize lattice oxygen in LaNi0.9Fe0.1O3 and ensure its long-term stability. Furthermore, it is vital interesting that activity of the reconstructed catalysts relied more on the surface chemistry rather than the reconstruction degree. The effect of Fe on the degree of surface reconstruction of the perovskite is decoupled from that on its activity enhancement after surface reconstruction. This finding showcases the importance to customize the surface chemistry of reconstructed catalysts for water oxidation.

关键词： Oxygen evolution reaction Perovskite oxides Doping Activation and reconstruction

Rock fracture mechanism of buffer blasting with cushion layer at the borehole bottom

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International journal of Minerals,Metallurgy and Materials 2025年第2期32卷 325-334页

作者： Xinguang Zhu chenxi Ding Zhe Sui hong Su Xu Guo School of civil and Resources Engineering University of Science and Technology BeijingBeijing 100083China Key Laboratory for Mechanics in Fluid Solid coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Mechanics and civil Engineering China University of Mining and Technology(Beijing)Beijing 100083China School of chemical and Blasting Engineering Anhui University of Science and TechnologyHuainan 232001China

This study primarily investigates the rock fracture mechanism of bottom cushion layer blasting and explores the effects of the bottom cushion layer on rock *** involves analyses of the evolution patterns of blasting stress,characteristics of crack distribution,and rock fracture features in the ***,blasting model experiments were carried out using the dynamic caustics principle to investigate the influence of bottom cushion layers and initiation methods on the integrity of the bottom rock *** experimental results indicate that the combined use of bottom cushion layers and inverse initiation effectively protects the integrity of the bottom rock ***,the process of stress wave propagation and dynamic crack propagation in rocks was simulated using the continuum-discontinuum element method(cDEM)and the Landau explosion source model,with varying thicknesses of bottom cushion *** numerical simulation results indicate that with increasing cushion thickness,the absorption of energy generated by the explosion becomes more pronounced,resulting in fewer cracks in the bottom rock *** illustrates the positive role of the cushion layer in protecting the integrity of the bottom rock mass.

关键词： bottom cushion layer blasting crack propagation continuum-discontinuum element method dynamic stress intensity factor

维普期刊数据库

Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

在线全文

学校读者我要写书评

暂无评论

Science china chemistry 2025年第1期 273-287页

作者： Shuguang Yang Lijun Hu hong Xiao Zecong Xiao Xintao Shuai PcFM Lab of Ministry of Education School of Materials Science and Engineering Sun Yat-sen University Department of Ultrasound The Fifth Affiliated Hospital Sun Yat-sen University Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen University Nanomedicine Research center The Third Affiliated Hospital of Sun Yat-sen University

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy. Nonetheless, the optimization of the catalytic efficiency is often impeded by the inefficient expression of enzymes. Herein, we reported a self-amplifying fluorescent molecular probe, Bis-HTPIcG, for photodynamic therapy(PDT) and subsequent PDT-induced immunoreaction. The Bis-HTP-IcG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO), a crucial enzyme secreted by neutrophils at inflammation sites. Upon exposure to laser irradiation, Bis-HTP-IcG showed a high PDT efficacy, inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO secretion. The heightened level of MPO enhances the accumulation of the Bis-HTP-IcG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis, instigating a self-amplifying chain reaction cycle involving Bis-HTP-IcG, neutrophils and ***, PDT efficiently incites immunogenic cell death(IcD) in tumor cells, initiating an anti-tumor immune response including dendritic cells(Dcs) maturation, T cell proliferation and reprogramming of tumor-associated neutrophils(TANs). This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

关键词：

同方期刊数据库

原位肝移植疑有肝动脉缺血病人的多普勒超声检查:中央和肝内动脉波形分析的作用

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2013年第3期 281-281页

作者： E.K.choi D.S.Lu S.H.Park j.c.hong S.S.Raman N.Ragavendra 柯勤兵 Departments of Radiology and Surgery Ronald Reagan UCLA Medical CenterDavid Geffen School of Medicine at UCLA

目的为了开发一种系统性方法检查原位肝移植怀疑肝动脉缺血病人的肝动脉,比较多普勒超声获取主要肝动脉(mainhepaticartery,MHA)及肝内动脉(intrahepaticartery,IHA)波形的联合参数的诊断价值。材料与方法本回顾性研究符合HIPAA标准,获... 详细信息

目的为了开发一种系统性方法检查原位肝移植怀疑肝动脉缺血病人的肝动脉,比较多普勒超声获取主要肝动脉(mainhepaticartery,MHA)及肝内动脉(intrahepaticartery,IHA)波形的联合参数的诊断价值。材料与方法本回顾性研究符合HIPAA标准,获得机构伦理委员会批准,免除签署知情同意书。从2002年1月1日—2011年11月1日,纳入189例成人病人(男129例,女60例;年龄18～73岁,平均53岁)的195个移植肝脏进行多普勒超声检查及间隔2周以内的随访(cT、MR或常规)血管造影。评价典型的IHA和MHA标准[阻力指数(RI)classicparvustarduswaveforms)]结合和不结合收缩期流速峰值(PSV)阈值(通过受试者操作特征曲线分析获取)的诊断价值。联合采用无血流分析和最优化MHA及IHA标准的结果创建一个算法,然后将其应用于所有的移植肝脏。结果采用典型标准(RIcm/s及39cm/s。在应用MHA及IHA标准时增加应用PSV阈值会导致总准确率显著下降(IHA:87%∶73%,P<0.001;MHA:82%∶66%,P=0.002)。这种算法的应用反映结合最优MHA及IHA标准和无血流分析结果的算法,可获得96%的敏感度和83%的特异度。结论这种特制的用于评价MHA和IHA乏血流区域分布、拥有定量参数以及波形形态的算法,可提高多普勒超声在检测原位肝移植的高危病人肝动脉并发症的能力。

关键词：原位肝移植 MHA IHA 正位肝移植肝动脉缺血多普勒超声检查肝内病人动脉

Sky location of massive black hole binaries in the foreground of Galactic white dwarf binaries

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science china(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 97-108页

作者： Pan Guo hong-Bo jin cong-Feng Qiao Yue-Liang Wu The International centre for Theoretical Physics Asia-Pacific University of Chinese Academy of Sciences The School of Physical Sciences University of Chinese Academy of Sciences Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University National Astronomical Observatories Chinese Academy of Sciences Institute of Theoretical Physics Chinese Academy of Sciences

For space-based gravitational wave （GW） detection,the main noise source for massive black hole binaries （MBHBs） is attributed to approximately 10～7double white dwarf binaries in the *** a GW source,the amplitude of the detector response,recorded by a space-based gravitational wave detector,exhibits a modulation effect with a year period when observing the source from various orbital *** the adverse conditions mentioned above,where there is a strong foreground noise and annual modulation in the signals,we employed the wavelet transform and the strong-amplitude relevant orbital position search methods,which allows the weak MBHB sources to achieve higher locating *** detail,for two MBHB sources of lower intensity,the precision of luminosity distance,represented by the ratio ?DL/DLat the 95%confidence level,is enhanced by factors of ～*** angular resolutions,denoted by??s,are enhanced by a factor of ～*** improvements increase the number of detectable GW sources,facilitate multi-messenger follow-up observations and provide constraints on the cosmological constant.

关键词： space-based gravitational wave detection gravitational waves massive black hole binaries