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Dietary supplementation of sulfur amino acids improves intestinal immunity to Eimeria in broilers treated with anti-interleukin-10 antibody

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Animal Nutrition 2022年第3期10卷 382-389页

作者： Zhouzheng Ren jiakun Yan Rose Whelan Xujie Liao Daniel E.bütz Maria K.Arendt Mark E.Cook Xiaojun Yang Thomas D.Crenshaw College of Animal Science and Technology Northwest A&F UniversityYanglingShaanxiChina Department of Animal Sciences University of WisconsinMadisonWIUSA Evonik Operations GmbH Hanau-WolfgangGermany

Oral antibody to interleukin-10(anti-IL-10)enhances the intestinal immune defense against *** sulfur amino acids methionine and cysteine(MtC)play essential roles in inducing and maintaining protective immune responses during intestinal ***,increased dietary MtC may support the anti-IL-10-induced intestinal immunity to ***(n=640)were arranged in a 2×2×2 factorial design with 2 levels of each of the 3 main factors:dietary standardized ileal digestible(SID)MtC levels(0.6%or 0.8%),dietary anti-IL-10 supplementation(with or without),and coccidiosis challenge(control or challenge).briefly,the broilers were supplied with either 0.6%or 0.8%SID MtC,each with or without anti-IL-10(300 mg/kg),from d 10 to *** d 14,broilers from each diet were gavaged with either PbS or *** resulting Eimeria infection induced fecal oocyst shedding and intestinal *** fed 0.8%SID MtC(main effects,P≤0.05)had decreased feed-to-gain ratio,increased duodenum and cecum luminal anti-Eimeria IgA titers,and decreased fecal oocyst counts,when compared to 0.6%SID *** supplementation of anti-IL-10(main effects,P≤0.05)increased cecum luminal total IgA concentration and decreased cecum ***(P≤0.05)were detected for growth performance and cecum luminal IFN-γ.briefly,the highest body weight gain and feed intake were reached in PbS-gavaged broilers fed 0.8%SID MtC with no anti-IL-10 and in Eimeria-challenged broilers fed 0.8%SID MtC with *** Eimeria-infected broilers,anti-IL-10 increased intestinal luminal IFN-γ and body weight gain only at 0.8%SID ***,anti-IL-10 increased intestinal luminal IFN-γ levels,decreased cecum lesions and restored growth only when fed with adequate amounts of sulfur amino *** findings underscore the importance of providing sufficient essential nutrients to support the anti-IL-10 induced immunity against coccidiosis.

关键词： Chicken Coccidiosis Egg yolk antibody Interleukin-10 Sulfur amino acid

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Alpha Defensins Genes and Vulvovaginal Candidiasis:A Study of Cases

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Open journal of Obstetrics and Gynecology 2015年第9期5卷 487-493页

作者： Humberto F boatto Elaine C.Francisco joao P.Kleine Ismael D.Silva Manoel j.b.C.Girao Alexandre P.Machado Olga Fischman Medical Clinic Department Medical FacultyUniversity of Mogi das CruzesMogi das CruzesBrazil Mycology Laboratory MicrobiolologyImmunology and Parasitology DepartmentFederal University of Sao PauloSao PauloBrazil Gynecology Department Federal University of Sao PauloSao PauloBrazil Molecular Oncology Research Center Barretos Cancer HospitalPio XII FoundationBarretosBrazil Microbiology Laboratory of Health basic Sciences Department Medical FacultyFederal University of Mato GrossoCuiabáBrazil

Objective: To evaluate the alpha-defensin (α-DF) genes polymorphism in women with vulvovaginal candidiasis and recurrence. Methods: This observational study included clinical vaginal secretion samples collected over four years from 88 women, ranging in age from 18 to 65 years, from medical centers of Sao Paulo and Mogi das Cruzes, brazil. Thirty-six of these women were asymptomatic (control group) and 52 presented clinical condition compatible with vulvovaginitis (38 primary or episodic as non-recurrent forms, and 14 recurrent vulvovaginal candidiasis). A portion of each sample was plated on Sabouraud dextrose agar with chloramphenicol and grown on CHROMagar Candida for presumptive characterization. The identification of the species was obtained by sequencing of the ITS1 region of rDNA. α-DF genes were amplified for subsequent evaluation of polymorphisms by endonuclease restriction assay. Results: From 88 samples were isolated 60 Candida albicans and 28 non-albicans Candida spp. Resistant C. albicans strains and non-albicans Candida spp. were more prevalent in recurrence. In all groups, the number of resistant non-albicans Candida spp. was most high than susceptible strains. α-DF1, α-DF3 and α-DF1/α-DF3 genotypes were found in 32 (36.4%), 17 (19.3%), 6 (6.8%) vaginal samples, respectively. About 33 samples were not amplified. Recurrence and severe disease were more observed in homozygous population. Conclusions: Non-albicans Candida spp. and homozygotic α-DF genotipes (α-DF1 and α-DF3) were more related with severe clinical signs and recurrence. Further studies about vulvovaginal candidiasis and α-DF genes are necessary to access the more comprehensive role of defensins in clinical manifestations.

关键词： Alpha-Defensin Genes Candida albicans Non-Albicans Candida Vulvovaginal Candidiasis Recurrent Vulvovaginal Candidiasis

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细针穿刺检测CA-15-3和癌胚抗原浓度对乳腺癌腋窝淋巴结转移的术前评估研究

2018年

作者： b+A编辑部

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国际医学放射学杂志 2010年第3期 266-266页

作者：张丽娜 M.j. Kim b.W. Park j.b. Lim H.S. Kim j.Y. Kwak S.j.Kim Department of Radiology Yonsei University Heath System250 Seongsan-no

摘要目的评价细针穿刺检测乳腺癌肿瘤标记物CA-15-3和癌胚抗原(CEA)的浓度在良恶性淋巴结中的差异是否有助于提高乳腺癌腋窝

关键词：淋巴结淋巴组织乳腺癌乳腺肿瘤腋窝细针穿刺癌胚抗原

Preparation of Ga_2O_3 thin film solar-blind photodetectors based on mixed-phase structure by pulsed laser deposition

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Chinese Physics b 2019年第1期28卷 171-177页

作者： Y M Lu C Li X H Chen S Han P j Cao F jia Y X Zeng X K Liu W Y Xu W j Liu D L Zhu College of Materials Science and Engineering Shenzhen Key Laboratory of Special Functional MaterialsShenzhen Engineering Laboratory for Advanced Technology of CeramicsGuangdong Research Center for Interfacial Engineering of Functional MaterialsShenzhen UniversityShenzhen 518060China

Gallium oxide(Ga_2O_3) thin films were deposited on a-Al2O3(1120) substrates by pulsed laser deposition(PLD) with different oxygen pressures at 650?C. by reducing the oxygen pressure, mixed-phase Ga_2O_3 films with α and β phases can be obtained, and on the basis of this, mixed-phase Ga_2O_3 thin film solar-blind photodetectors(SbPDs) were *** the responsivities of the mixed-phase Ga_2O_3 SbPDs and the single β-Ga_2O_3 SbPDs at a bias voltage of 25 V,it is found that the former has a maximum responsivity of approximately 12 A/W, which is approximately two orders of magnitude larger than that of the latter. This result shows that the mixed-phase structure of Ga_2O_3 thin films can be used to prepare high-responsivity SbPDs. Moreover, the cause of this phenomenon was investigated, which will provide a feasible way to improve the responsivity of Ga_2O_3 thin film SbPDs.

关键词： Ga2O3 mixed-phase solar-blind photodetector pulsed laser deposition

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自动化工具QyScore?快速测量脑萎缩和白质高信号的验证研究

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国际医学放射学杂志 2022年第4期 487-488页

作者： E.Cavedo P.Tran U.Thoprakarn j.b.Martini A.Movschin C.Delmaire 张晓涵

摘要目的 Qy Score R是一种在欧洲（CE认证）和美国（FDA批准）获得认证的影像分析工具，可自动测量灰质（GM）和白质（WM）、海马（HP）、杏仁核（AM）、WM高信号

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ie Condensation Characterization of SiGe-On-Insulator Structure fabricated by Separation of Oxygen Implantation

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ie Condensation Characterization of SiGe-On-Insulator Struct...

Cellular Auxin Homeostasis： Gatekeeping Is Housekeeping

2004 7th International Conference on Solid-State and Integrated Circuits Technology（ICSICT 2004）

作者： Z.j.Chen~3 F.Zhang ~(a b) Z.X Zhang~a j.b.~a X Wang ~(a b) S.C.Zou~a a The Research Center Of Semiconductor Functional Film Engineering Technology Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Shanghai 200050 China b Shanghai SIMGUI Technology Co. LTD 200 Puhui Road jiading Shanghai 201821 China

＜正＞In this paper we present a virtual strained silicon substrate,full relaxed SiGe-on-insulator （SGOI）（Ge%=15%）structure with stepwise buffer layers and high quality box layer,fabricated by separation by implantation of oxygen（SIMOX）*** condensation effect of the top SiGe layer is found and its dependence on the SIMOX parameters was also *** result can propose an unique way to get high Ge content of SGOI /Si heterostructures.

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Molecular Plant 2012年第4期5卷 772-786页

作者： Michel Ruiz Rosquete Department of Applied Genetics and Cell biology University of Applied Life Sciences and Natural Resources (BOKU) 1190 Vienna Austria Department of Plant Systems biology VIB and Department of Plant Biotechnology and Bioinformatics Ghent University 9052 Gent Belgium

The phytohormone auxin is essential for plant development and contributes to nearly every aspect of the plant life cycle. The spatio-temporal distribution of auxin depends on a complex interplay between auxin metabolism and cell-to-cell auxin transport. Auxin metabolism and transport are both crucial for plant development; however, it largely remains to be seen how these processes are integrated to ensure defined cellular auxin levels or even gradients within tissues or organs. In this review, we provide a glance at very diverse topics of auxin biology, such as biosynthesis, conjugation, oxidation, and transport of auxin. This broad, but certainly superficial, overview highlights the mutual importance of auxin metabolism and transport. Moreover, it allows pinpointing how auxin metabolism and transport get integrated to jointly regulate cellular auxin homeostasis. Even though these processes have been so far only separately studied, we assume that the phytohormonal crosstalk integrates and coordinates auxin metabolism and transport. besides the integrative power of the global hormone signaling, we additionally introduce the hypothetical concept considering auxin transport components as gatekeepers for auxin responses.

关键词： auxin conjugation auxin homeostasis auxin metabolism auxin transport.

Mapping Short Affinity Tags on bacterial S-Layer Nanoarrays with Molecule Recognition Imaging

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Mapping Short Affinity Tags on Bacterial S-Layer Nanoarrays ...