检索结果-南通市图书馆

iNVESTiGATiON OF ARCHiTECTURAL STRATEGieS iN RELATiON TO DAYLiGHT AND iNTEGRATED DESiGN-A CASE STUDY OF THREE LiBRARieS iN DENMARK

在线全文

学校读者我要写书评

暂无评论

journal of Green Building 2012年第1期7卷 40-54页

作者： Michael jørgensen Anne iversen lotte Bjerregaard jensen Department of Civil Engineering Technical University of Denmark

This paper investigates the use of daylight in three architecturally successful *** aim is to discuss the challenges and opportunities of architectural daylight strategies in relation to integrated *** these buildings were designed with the focus on a strategy of using daylight to create well-lit,exciting spaces and spatial *** original ideas,thoughts,and decisions behind the designs and daylight strategy are compared with answers in questionnaires from test subjects who have experienced the space and lighting conditions *** results indicate that the architectural daylight strategies formulated by the architects and engineers at the beginning of the design process are actually experienced by the“users”in the existing *** architectural daylight strategy was different in each of the three libraries,and analysis of the results shows that daylight strategies that include spatial considerations received more positive ***,the study showed that designs aimed at achieving an even distribution of daylight with an illuminance target of 200 lx did not result in higher evaluation of the daylight design.

关键词： daylight integrated design work methods

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBi)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBis are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

Effect of Multiple Martensitic Transformations on Structure of Fe-Ni Alloys

在线全文

学校读者我要写书评

暂无评论

journal of Materials Science & Technology 2013年第3期29卷 279-282页

作者： V.Danilchenko ie.Dzevin V.Sagaradze G.V.Kurdyumov institute of Metal Physics NAS of UkraineKievUkraine institute of Metal Physics Ural Division of RASEkaterinburgRussia

Effect of multiple direct and reverse martensitic transformations on fragmentation of austenitic grains in Fe-Ni alloys have been studied by X-ray diffraction and scanning electron microscopy. An ultra-fine structure was formed by fragmentation inside austenitic grains due to progressing misorientation of austenitic sub-grains during multiple γ-α-γ-martensitic phase transitions. An increase in the number of γ-α-γ-transformations increases misorientation angle between austenitic sub-grains and leads to transformation of an austenitic single crystal into a textured polycrystal. it has been shown that multiple γ-α-γ-martensitic phase transitions change the mechanism of internal stress relaxation from dislocation-based to deformation twinning.

关键词： Austenite Crystal lattice Ultra-fine structure Martensitic transformation

Multisensory mechanisms of gait and balance in Parkinson’s disease:an integrative review

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 82-92页

作者： Stiven Roytman Rebecca Paalanen Giulia Carli Uros Marusic Prabesh Kanel Teus van Laar Nico i.Bohnen Department of Radiology University of MichiganAnn ArborMIUSA Department of Neurology University of MichiganAnn ArborMIUSA Morris K.Udall Center of Excellence for Parkinson’s Disease Research University of MichiganAnn ArborMIUSA institute for Kinesiology Research Science and Research Centre KoperKoperSlovenia Department of Health Sciences Alma Mater Europaea–ECMMariborSlovenia Parkinson’s Foundation Research Center of Excellence University of MichiganAnn ArborMIUSA Department of Neurology University of GroningenUniversity Medical Center GroningenGroningenThe Netherlands Neurology Service and GRECC VA Ann Arbor Healthcare SystemAnn ArborMIUSA

Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging *** and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous *** effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory *** mechanisms which underpin the integration of these multisensory signals are the principal topic of the present *** multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older *** emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and *** the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s *** also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older ***,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.

关键词： aging balance encephalography functional magnetic resonance imaging gait multisensory integration Parkinson’s disease positron emission tomography somatosensory vestibular visual

Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.Gunn Laura Bennet Hamid Abbasi Mātai Medical Research institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

Expression and Activity Analysis of Non-Structural Protein 2 (NS2) of Bombyx mori Densovirus Zhenjiang Strain

在线全文

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2010年第12期9卷 1821-1828页

作者： ZHAO Pan TANG Shun-ming LiU Tingx LiU Ting QiN Guang-xing GUO Xi-j ie College of Biotechnology and Environmental Engineering Jiangsu University of Science and Technology Zhenjiang 212003 P.R.China Key Laboratory of Silkworm and Mulberry Genetic improvement Ministry of Agriculture of China/Sericultural Research Institute Chinese Academy of Agricultural Sciences Zhenjiang 212018 P.R.China

The gene of the non-structure protein 2 （NS2） was cloned by PCR from the genome ofBombyx mori densovirus Zhenjiang strain （BmDNV-Z）, inserted into prokaryotic expression vector pET28a to construct recombinant plasmid pET28a-NS2 and then expressed in bacteria Escherichia coli BL21 （DE3）. The expressed recombinant protein was identified by SDS-PAGE and Western blot analysis. Then, the recombinant protein was purified by Ni-NTA column, renatured and tested for enzyme activities. The purified NS2 protein exhibited a helicase activity unwinding double-stranded DNA substrates into single-strand primers, and higher unwinding activity to polarity substrate. Similarly, the purified NS2 protein possessed an ATPase activity and its enzyme activity was 0.276 μmol gg^-1 h^-1 in this study. The results indicated that the non- structure protein which encoded by the gene of BmDNV-Z NS2 possesses the biological activities of helicase and ATPase, and the helicase prefers to polarity substrates. Based on these results, it is speculated that the gene of BmDNV-Z NS2 plays an important role in the viral DNA replication.

关键词： Bombyx mori densovirus non-structure protein expression activity

SUSTAiNABiLiTY CERTiFiCATiON SYSTEMS AS GUiDELiNES FOR EARLY-PHASE URBAN DESiGN PROCESSES

在线全文

学校读者我要写书评

暂无评论

journal of Green Building 2016年第3期11卷 81-94页

作者： lotte B.jensen Lærke Bjerre Lise Mansfeldt Technical University of Denmark Department of Civil Engineering

The German Sustainable Building Council(Deutsche Gesellschaft für Nachhaltiges Bauen or DGNB)has one of the most comprehensive sustainability certification systems for urban districts(UD).Their explicit aim is that the system should impact the very earliest design *** Technical University of Denmark has tested the DGNB-UD system in two experimental design projects for similar locations to find out how it can be used in the early-phase design *** paper describes these two independent design processes,compares them and discusses their general *** found that DGNB-UD addresses a broad sustainable focus and can be used as a tool for setting sustainability goals from the very first design *** system tends to promote multifunctional compromise solutions that meet several criteria at the same *** the DGNB-UD certification system in the early design phases therefore does have some effect on the urban design in terms of a bias towards certain design traits.

关键词： urban design urban design drivers ealiest design phases German Sustainable Building Council

Apolipoprotein A-i binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo Hwang Seunghwan Choi Soo-Ho Choi Keun-Young Kim Yury i.Miller Won-Kyu ju Hamilton Glaucoma Center and Shiley Eye institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

Prognostic impact of inflammatory and nutritional biomarkers in pancreatic cancer

在线全文

学校读者我要写书评

暂无评论

World journal of Clinical Oncology 2025年第1期16卷 5-9页

作者： Macarena Teja María i Garrido Abrahams Ocanto Felipe Counago Department of Radiation Oncology GenesisCare-San Francisco de Asís University HospitalMadrid 28002Spain Department of Radiation Oncology GenesisCare-Vithas La Milagrosa University HospitalMadrid 28010Spain National Director GenesisCare SpainMadrid 28043Spain Department of Medicine School of MedicineHealth and SportEuropean University of MadridMadrid 28670Spain

Pancreatic cancer is usually associated with a poor *** is the main curative treatment but pancreatic operations are aggressive and new tools that help clinicians to predict surgical and prognostic outcomes are *** et al recently published a retrospective,single centre cohort study evaluating the impact of seven nutritional and inflammatory markers in pancreatic cancer surgical patients:The albumin-to-globulin ratio,prognostic nutritional index(PNi),systemic immune-inflammation index(Sii),neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),nutritional risk index,and the geriatric nutritional risk index.A significant correlation was found between the PNi,Sii,NLR,and PLR and a hospital discharge of less than 15 *** a univariable analysis,PNi,Sii,NLR and PLR were significantly related to recurrence-free survival and,in a multivariable analysis PNi was associated with overall *** meta-analyses corroborate the results in terms of prognosis but individual studies are discordant on their ***,the cut-off values for these markers vary significantly between studies and there are no clinical trials comparing them to identify the most relevant *** are limitations when implementing nutritional and inflammatory biomarkers into clinical practice and further studies are needed in order to answer these questions.

关键词： inflammatory biomarkers Nutritional biomarkers Pancreatic cancer Prognosis Surgical complications