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journal of Advanced Dielectrics 2021年第3期11卷 8-15页

作者： j.a.cortés j.Camargo M.F.Rachia F.Rubio-Marcos L.Ramajo M.Castro M.A.Ramírez sao Paulo state University—UNEsP Faculty of Engineering of Guaratingueta.Av.Dr.Ariberto Pereira da Cunha 333 Portal das Colinas 12516-410GuaratinguetaSPBrazil Research Institute for Materials science and Technology INTEMA Av.Colon 10850B7608FDQ Mar del PlataArgentina Electroceramics Department Instituto de Cerámica y Vidrio CSICKelsen 528049MadridSpain Escuela Politécnica superior.Universidad Antonio de Nebrija Pirineos 55 28040MadridSpain

The effect of sintering condition on structure,microstructure,and ferroelectric properties of(K_(0.44)Na_(0.52)Li_(0.04))(Nb_(0.86)Ta_(0.10)sb_(0.04))-O_(3)(KNL-NTs)has been *** powders have been synthesized by the solid-state reaction method and sintered at different temperatures(1115℃,1125℃,and 1140℃).Then,samples were characterized by thermogravimetric analysis,X-ray diffraction,scanning electron microscopy,and impedance *** XRD results,the perovskite structure and small peaks corresponding to a secondary phase were *** processed at the highest temperatures showed higher densities and good piezoelectric properties(d_(33),K_(p),and K_(t)),particularly specimens sintered at 1125℃ presented the highest piezoelectric performance.

关键词： KNL-NTs lead-free ferroelectric properties

Efficiency and effectiveness of systems for the treatment of domestic wastewater based on subsurface flow constructed wetlands in jarabacoa, Dominican Republic

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Water science and Engineering 2024年第2期17卷 118-128页

作者： Yvelisse Pérez Enmanuel Vargas Daniel Garcia-cortes William Hernandez Humberto Checo Ulises jauregui-Haza Area de Ciencias Basicas y Ambientales Instituto Tecnologico de Santo Domingo(INTEC)Avenida de Los Proceres 49Los Jardines del NorteSanto Domingo 10602Dominican Republic Ministry of Environment and Natural Resources Calle Cayetano Germosen esq.Ave.LuperonEl PedregalSanto Domingo 11107Dominican Republic Plan Yaque Calle Estela Geraldino 14 AltosJarabacoa 41000Dominican Republic Institute of Technologies and Applied sciences University of HavanaHavana 10400Cuba

Constructed wetlands(CwW)are well known nature-based systems for water *** study evaluated the efficiency and effectiveness of seven domestic wastewater treatment systems based on horizontal flow CWs in jarabacoa,the Dominican *** results showed that the CWs were efficient in reducing the degree of contamination of wastewater to levels below the Dominican wastewater discharge standards for parameters such as the 5-day biochemical oxygen demand(BOD5)and chemical oxygen demand,but not for the removal of phosphorus and fecal *** addition,a horizontal flow subsurface wetland in the peri-urban area El Dorado was evaluated in terms of the performance of wastewater treatment in tropical climatic *** concentrations of heavy metals,such as zinc,copper,chromium,and iron,were found to decrease in the effluent of the wetland,and the concentrations for nickel and manganese tended to *** levels of heavy metals in the effluent were lower than the limit values of the Dominican wastewater discharge *** construction cost of these facilities was around 200 UsD per population equivalent,similar to the cost in other countries in the same *** study suggested some solutions to the improved performance of CWs:selection of a microbial flora that guarantees the reduction of nitrates and nitrites to molecular nitrogen,use of endemic plants that bioaccumulate heavy metals,combination of constructed wetlands with filtration on activated carbon,and inclusion of water purification processes that allow to evaluate the reuse of treated water.

关键词： Domestic wastewater Constructed wetland BOD COD Pathogens Heavy metals

AAsLD practice guidance on drug,herbal,and dietary supplement-induced liver injury:also useful for hepatobiliary surgeons

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Hepatobiliary surgery and Nutrition 2023年第5期12卷 746-751页

作者： jose María Pinazo-Bandera Miren García-cortés Raúl j.Andrade service of Gastroenterology and Hepatology University Hospital Virgen de la VictoriaInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BionandUniversidad de MálagaMálagaSpain Centro de Investigación Biomédico en Red Enfermedades Hepáticas y Digestivas(CIBERehd) MadridSpain

Drug-induced liver injury(DILI)is a term used to describe an unexpected liver reaction to drugs,but also to herbal products and dietary supplements(HDs).In the current therapeutic armamentarium,only a small number of available drugs are still capable of causing liver damage in *** include,in addition to paracetamol-the prototypical example of this group-niacin(now rarely used to treat hypercholesterolaemia),intravenous methotrexate and probably ketamine(an intravenous hypnotic used in critically ill patients for rapid sequence induction)(1).

关键词： Drug-induced liver injury(DILI) hepatotoxicity causality assessment Revised Electronic Causality Assessment Method(RECAM)

Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer

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四川生理科学杂志 2022年第2期44卷 374-374页

作者： javier cortés From the International Breast Cancer Center Quirónsalud Group Barcelona the Scientific Department Medica Scientia Innovation Research Valencia and the Department of Medicine Faculty of Biomedical and Health Sciences Universidad Europea de Madrid Madrid - all in Spain (J. Cortés) Asan Medical Center University of Ulsan College of Medicine Ulsan (S.-B.K.) Seoul National University Hospital Cancer Research Institute (S.-A.I.) and Seoul National University Bundang Hospital (J.H.K.) Seoul National University College of Medicine and Samsung Medical Center (Y.H.P.) Seoul and Severance Hospital Yonsei University Yonsei (M.H.K.) - all in South Korea the Department of Oncology National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan (W.-P.C.) and the Department of Surgery Taipei Veterans General Hospital College of Medicine National Yang-Ming Chiao Tung University (L.-M.T.) Koo Foundation Sun Yat-Sen Cancer Center (C.-F.C.) and National Taiwan University Hospital and National Taiwan University College of Medicine (C.-S.H.) Taipei - all in Taiwan Clínica de Pesquisas e Centro de Estudos em Oncologia Ginecológica e Mamária (R.H.) and Instituto do Câncer do Estado de são Paulo Octavio Frias de Oliveira (V.P.) São Paulo and Hospital Nossa Senhora da Conceição Porto Alegre (J.L.P.) - all in Brazil Aichi Cancer Center Hospital Aichi Japan (H.I.) sarah Cannon Research Institute Tennessee Oncology Nashville (E.H.) the Department of Oncology and Hematology-Oncology University of Milan and the Division of Early Drug Development European Institute of Oncology Istituto di Ricovero e Cura a Carattere Scientifico - both in Milan (G.C.) the Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing (B.X.) the University of Hong Kong Hong Kong (J.W.Y.C.) Daiichi sankyo Basking Ridge NJ (C.L. Y.L. J. Cathcart E.B.) AstraZeneca Gaithersburg MD (S.V.) and the David Geffen school of Medicine and jonsson Comprehensive

Background:Trastuzumab emtansine is the current standard treatment for patients with human epidermal growth factor receptor 2(HER2)-positive metastatic breast cancer whose disease progresses after treatment with a combination of anti-HER2 antibodies and a ***:We conducted a phase 3,multicenter,open-label,randomized trial to compare the efficacy and safety of trastuzumab deruxtecan(a HER2 antibody-drug conjugate)with those of trastuzumab emtansine in patients with HER2-positive metastatic breast cancer previously treated with trastuzumab and a *** primary end point was progression-free survival(as determined by blinded independent central review);secondary end points included overall survival,objective response,and safety.

关键词： Trastuzumab HER2 Breast

Computational algorithms for simulating the grain structure formed on steel billets using cellular automaton and chaos theories

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International journal of Minerals,Metallurgy and Materials 2011年第1期18卷 24-34页

作者： A.Ramírez-López G.soto-cortés j.González-Trejo D.Muoz-Negrón Department of Materials Metropolitan Autonomous University Institute Polytechnic National Institute Technologic Autonomous of Mexico

The development of some computational algorithms based on cellular automaton was described to simulate the structures formed during the solidification of steel *** algorithms described take results from the steel thermal behavior and heat removal previously calculated using a simulator developed by present authors in a previous *** time is used for displaying the steel transition from liquid to mushy and *** it is also used to command computational subroutines that reproduce nucleation and grain *** routines are logically programmed using the programming language C＋＋ and are based on a simultaneous solution of numerical methods （stochastic and deterministic） to create a graphical representation of different grain structures *** grain structure obtained is displayed on the computer screen using a graphical user interface （GUI）.The chaos theory and random generation numbers are included in the algorithms to simulate the heterogeneity of grain sizes and morphologies.

关键词： continuous casting solidification grain growth algorithms computer simulation

On the Origin of the Common Bean (<i>Phaseolus vulgaris</i>L.)

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American journal of Plant sciences 2013年第10期4卷 1998-2000页

作者： Andrés j. cortés Departamento de Biologia Universidad de los Andes Bogotá Colombia

Phylogeographic methods provide the tools to accurately access the geographic origin and diversification of crop species. In the present commentary, I urge the common bean community to face those methods and a tree-thinking mentality with regards to the long standing debate of the origin of common bean. such efforts will ultimately bring back interest into wild bean studies and reinforce the uniqueness of this species as a system to study diversification, domestication and adaptive processes across the two most diverse hotspots in the world.

关键词： Phylogeography Domestication Bottlenecks Outgroups Andes Mesoamerica

MEAN AND RANGE OF THE AMBULATORY PREssUREIN NORMOTENsIVE sUBjECTs

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中华医学杂志(英文版) 1992年第4期105卷 328-333页

作者： j staessen C Guo P De cort R Fagard P Lijnen L Thijs R Van Hoof A Amery Hypertension and Cardiovascular Rehabilitation Unit Department of Pathophysiology University of Leuven Belgium

To perform a meta-analysis of published reportsin an attempt to determine the mean and range ofnormal ambulatory blood pressure(BP),23 studies in-cluding a total of 3 476 normal subjects *** studies were compatible with a mean24-h BP in the range of 115-120/70-75mmHg,amean day time BP of 120-125/75-80mmHg,and amean night time BP of 105 to 110/60 to 65 *** weighting for the number of subjects included inthe individual studies,the 24-h BP averaged 118/72mmHg,the day time BP 123/76 mmHg,and thenight time BP 106/64 *** night/day pres-sure ratio averaged 0.87 for systolic and 0.83 fordiastolic BP,with ranges across the individual studiesfrom 0.79 to 0.92 and from 0.75 to 0.90,*** the mean ± 2 standard deviation interval in the va-rious studies was considered normal,the range ofnormality was on average 97 to 139/57 to 87 mmHgfor the 24-h BP,101 to 146/61 to 91 mmHg for theday time BP,and 86 to 127/48 to 79 mmHg for thenight time *** the results of prospective studieson the relation between the ambulatory BP and the in-cidence of cardiovascular morbidity and mortality be-come available,the aforementioned intervals,whichsummarize the experience of 23 investigators,couldserve as a temporary reference for clinical practice.

关键词： BLOOD-PREssURE HYPERTENsION VALUEs AGE

Numerical Integration of Forced and Damped Oscillators through a New Multistep Method

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journal of Applied Mathematics and Physics 2019年第10期7卷 2440-2458页

作者： M. cortés-Molina F. García-Alonso j. A. Reyes Department of Applied Mathematics Escuela Politécnica Superior University of Alicante Alicante Spain

Forced and damped oscillators appear in the mathematical modelling of many problems in pure and applied sciences such as physics, engineering and celestial mechanics among others. Although the accuracy of the T-functions series method is high, the calculus of their coefficients needs specific recurrences in each case. To avoid this inconvenience, the T-functions series method is transformed into a multistep method whose coefficients are calculated using recurrence procedures. These methods are convergent and have the same properties to the T-functions series method. Numerical examples already used by other authors are presented, such as a stiff problem, a Duffing oscillator and an equatorial satellite problem when the perturbation comes from zonal harmonics j2.

关键词： Numerical solutions of ODE’s Perturbed and Damped Oscillators Initial Value Problems (IVP) Multistep Methods

Flexible, diamond-based microelectrodes fabricated using the diamond growth side for neural sensing

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Microsystems & Nanoengineering 2020年第1期6卷 742-753页

作者： Bin Fan Cory A.Rusinek cort H.Thompson Monica setien Yue Guo Robert Rechenberg Yan Gong Arthur j.Weber Michael F.Becker Erin Purcell Wen Li Department of Electrical and Computer Engineering Michigan State UniversityEast LansingMIUSA Fraunhofer UsA Center for Coatings and Diamond Technologies East LansingMIUSA Department of Biomedical Engineering Michigan State UniversityEast LansingMIUSA Department of Physiology Michigan State UniversityEast LansingMIUSA

Diamond possesses many favorable properties for biochemical sensors,including biocompatibility,chemical inertness,resistance to biofouling,an extremely wide potential window,and low double-layer *** hardness of diamond,however,has hindered its applications in neural implants due to the mechanical property mismatch between diamond and soft nervous ***,we present a flexible,diamond-based microelectrode probe consisting of multichannel boron-doped polycrystalline diamond(BDD)microelectrodes on a soft Parylene C *** developed and optimized a wafer-scale fabrication approach that allows the use of the growth side of the BDD thin film as the sensing *** to the nucleation surface,the BDD growth side exhibited a rougher morphology,a higher sp^(3) content,a wider water potential window,and a lower background *** dopamine(DA)sensing capability of the BDD growth surface electrodes was validated in a 1.0 mM DA solution,which shows better sensitivity and stability than the BDD nucleation surface *** results of these comparative studies suggest that using the BDD growth surface for making implantable microelectrodes has significant advantages in terms of the sensitivity,selectivity,and stability of a neural ***,we validated the functionality of the BDD growth side electrodes for neural recordings both in vitro and in *** biocompatibility of the microcrystalline diamond film was also assessed in vitro using rat cortical neuron cultures.

关键词： neural film diamond

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气候干湿指数的改进

干旱区地理 1993年第3期16卷 90-92页

作者： cort Willmott johannes j. Feddema 艾东特拉华大学加利福尼亚大学

作者探讨了***等人曾普遍使用的气候干湿指数(Im),认为该指数存在着任意范围[—100≤Im≤100(∞—1)]及其无量纲性的缺陷。并提出了该指数的改进形式。改进形式虽然也是无量纲的,但范围改成—1≤Im≤1。湿润气候Im为正值,干燥气候Im为负... 详细信息

作者探讨了***等人曾普遍使用的气候干湿指数(Im),认为该指数存在着任意范围[—100≤Im≤100(∞—1)]及其无量纲性的缺陷。并提出了该指数的改进形式。改进形式虽然也是无量纲的,但范围改成—1≤Im≤1。湿润气候Im为正值,干燥气候Im为负值,并以零为对称中心。文章描述了修改后的世界各大陆年平均干湿指数的空间分布状况。

关键词：气候干湿指数