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Em.rging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William.j.Flerlage m.rk L.Dell’Acqua Brian m.Cox Fereshteh S.Nugent Uniform.d Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Departm.nt of Pharm.cology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a m.j.r contributor to neural circuit and network disruption underlying em.tional and m.od dysregulation in psychiatric disorders(Sim.ons et al.,2024).Diverse sets of distinct m.lecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through com.lex interactions organized by num.rous m.ltivalent protein scaffolds,including the fam.ly of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

A New Arrangem.nt with Nonlinear Sidewalls for Tanker Ship Storage Panels

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j.urnal of Ocean University of China 2013年第1期12卷 23-31页

作者： m. j. Ketabdari H. Saghi Faculty of m.rine Technology Amirkabir University of Technology Departm.nt of Civil Engineering Ferdowsi University

Sloshing phenom.non in a m.ving container is a com.licated free surface flow problem. It has a wide range of engineering applications, especially in tanker ships and Liquefied Natural Gas (LNG) carriers. When the tank in these vehicles is partially filled, it is essential to be able to evaluate the fluid dynam.c loads on tank perim.ter. Different geom.tric shapes such as rectangular, cylindrical, elliptical, spherical and circular conical have been suggested for ship storage tanks by previous researchers. In this paper a num.rical m.del is developed based on incom.ressible and inviscid fluid m.tion for the liquid sloshing phenom.non. The coupled BEm.FEm.is used to solve the governing equations and nonlinear free surface boundary conditions. The results are validated for rectangular container using data obtained for a horizontal periodic sway m.tion. Using the results of this m.del a new arrangem.nt of trapezoidal shapes with quadratic sidewalls is suggested for tanker ship storage panels. The suggested geom.tric shape not only has a m.xim.m.surrounded tank volum. to the constant available volum., but also reduces the sloshing effects m.re efficiently than the existing geom.tric shapes.

关键词： tanker ships storage panels sloshing phenom.non quadratic sidewalls

On the Structure of Graded Leibniz Algebras

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Algebra Colloquium 2015年第1期22卷 83-96页

作者： Antonio j. Calderon m.rtin j.se m. Sfinchez Delgado Departam.nto de m.tem.ticas Universidad de Cadiz 11510 Puerto Real Cadiz Spain

We study the structure of graded Leibniz algebras with arbitrary dim.nsion and over an arbitrary base field K. We show that any of such algebras ￡ with a sym.etric G-support is of the form.￡ = U-∑j.j.with U a subspace of ￡1, the hom.geneous com.onent associated to the unit elem.nt 1 in G, and any Ij.a well described graded ideal of ￡, satisfying [Ij. Ik]= 0 if j. k. In the case of ￡ being of m.xim.l length, we characterize the gr-sim.licity of the algebra in term. of connections in the support of the grading.

关键词： graded Leibniz algebra infinite dim.nsional Leibniz algebra structure theory

Potential gains from.spatially-explicit coordinated planning between two large public ownerships in m.nnesota

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Forest Ecosystem. 2019年第2期6卷 102-118页

作者： j.shua j. Bixby Howard m. Hoganson Yu Wei Geospatial System. Engineer USDA Forest Service Chief’s Information Office Duluth MN USA Departm.nt of Forest Resources and North Central Research and Outreach Center University of MN Grand Rapids MN USA Departm.nt of Forest and Rangeland Stewardship Colorado State University Fort Collins CO USA

Background: m.ny forested landscapes throughout the world involve a m.x of public forest ownerships. This study explores how coordinated planning between two large public ownerships in m.nnesota im.act landscape-level trade-offs between tim.er production and production of core area of older forest (COF) for the region. COF is an im.ortant m.tric for wildlife habitat. Em.hasis is on better understanding potential gains from.both coordinated planning at the site-level where ownerships share stand boundaries and from.coordinated planning at a broader policy level involving assum.d values of COF by the public. The study area involves over 300,000 ha, 150,000 analysis units and a 100-year planning horizon. m.thods: The concept of influence zones in m.deling spatial interdependencies is described and im.lem.nted. The estim.ted total area of COF is assum.d an im.ortant landscape m.tric for forest wildlife habitat condition for each forest planning period. COF has a surrounding buffer protecting it from.edge effects. Differences are recognized between COF condition requirem.nts and condition requirem.nts for its surrounding buffer. A spatially-explicit harvest scheduling m.del is applied in conj.nction with m.ving-windows techniques of GIS to find near-optim.l m.nagem.nt schedules for the large landscape. m.ltiple m.del runs are exam.ned to help better understand both potential gains from.coordinated planning and the tradeoffs between tim.er and COF production. Results: Results dem.nstrate the ability to incorporate detailed site-level COF production into m.nagem.nt scheduling m.dels for broad, landscape-level planning. For the study area and the assum.d COF definitions, substantially larger gains are possible by coordinating COF value assum.tions across ownerships, as com.ared to possible gains from.coordinating on-the-ground m.nagem.nt activities in areas involving shared stand boundaries. Although a general m.p of the study area shows a definite intertwining m.saic of ow

关键词： Core area Interior space Trade-off analysis m.ltiple obj.ctive planning Landscape planning Harvest scheduling Patch size Production possibilities frontier

Inform.tion Transm.ssion in Phase Synchronous Chaotic Arrays

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Chinese Physics Letters 2006年第3期23卷 560-563页

作者： m. S. Baptista C. Zhou j. Kurths Universitat Potsdam Institut for Physik Am Neuen Palais 10 D-14469 Potsdam Deutschland

We show m.ny versatile phase synchronous configurations that em.rge in an array of coupled chaotic elem.nts due to the presence of a periodic stim.lus. Then, we explain the relevance of these configurations to the understanding of how inform.tion about such a stim.lus is transm.tted from.one side to the other in this array. The stim.lus actively creates the ways to be transm.tted, by m.king the chaotic elem.nts to phase synchronize.

关键词： NEURAL SPIKE TRAINS SYNCHRONIZATION

Phosphorus export by runoff from.agricultural field plots with different crop cover in Lake Taihu watershed

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j.urnal of Environm.ntal Sciences 2001年第4期13卷 502-507页

作者： Yan, W.-j. Huang, m.-x. Zhang, S. Tang, Y.-j. Dept. of Envrn. Biogeochem.stry Inst.Geographic Sci./Nat. Rsrc. Res. Chinese Academy of Sciences Beijing 100101 China

Runoff and soil losses from.agricultural fields are investigated as m.j.r nonpoint sources of phosphorus (P) entering lakes of Eastern China. There is relatively little inform.tion on P transport from.ricefield and cropland of Lake Taihu watershed in Eastern China. Soil and P in surface runoff from.a series of plots in the watershed were evaluated under sim.lated rainfall conditions. The obj.ctives of this study were to evaluate the effects of crop cover, slope, and fertilizer application on P concentrations in surface runoff and eroded soil. Accum.lated sedim.nt yields varied from.7.1 to 300 g/m. for croplands, depending on m.nagem.nt practices. For all experim.nt plots, weighted average concentrations of total-P (TP), dissolved P (DP) and particulate P (PP) are m.ch higher than 0.02 m./L, the lim.ting concentration for lake water. This result showed the potential contam.nation of lake water from.agricultural surface runoff. Accum.lated TP losses were 3.8 and 18.8 m./m. for ricefield and cropland, respectively. The estim.ted annual loss of TP was 0.74 kg/(hm. &m.ddot a) for cropland. m.st of P loss is in the PP form. which accounts for m.re than 90% of TP loss for cropland.

关键词： Concentration (process) Crops Lakes Phosphorus Sedim.nts Soils Watersheds

Processing and m.chanical properties of porous 316L stainless steel for biom.dical applications

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中国有色金属学会会刊：英文版 2007年第3期17卷 468-473页

作者： m.ntasser m. DEWIDAR Khalil A. KHALIL j. K. LIm Departm.nt of m.chanical Design and m.terials High Institute of Energy South Valley University Aswan Egypt Material and Fracture Laboratory Department of Mechanical Design Chonbuk National University Duckjin 1-664-14 Jeonju JB561-756 South Korea Departm.nt of m.chanical Design and m.terials High Institute of Energy South Valley University Aswan Egypt Autom.bile Hi-Technology Research Institute Faculty of Mechanical and Aerospace System Engineering Chonbuk National University Duckjin 1-6 64-14 Jeonju JB 561-756 South Korea

Highly porous 316L stainless steel parts were produced by using a powder m.tallurgy process, which includes the selective laser sintering(SLS) and traditional sintering. Porous 316L stainless steel suitable for m.dical applications was successfully fabricated in the porosity range of 40%-50% (volum. fraction) by controlling the SLS param.ters and sintering behaviour. The porosity of the sintered com.acts was investigated as a function of the SLS param.ters and the furnace cycle. Com.ressive stress and elastic m.dulus of the 316L stainless steel m.terial were determ.ned. The com.ressive strength was found to be ranging from.21 to 32 m.a and corresponding elastic m.dulus ranging from.26 to 43 GPa. The present parts are prom.sing for biom.dical applications since the optim.l porosity of im.lant m.terials for ingrowths of new-bone tissues is in the range of 20%-59% (volum. fraction) and m.chanical properties are m.tching with hum.n bone.

关键词：不锈钢激光烧结处理方法金属

Effect of Laser Inj.ction Seeder on Rotationally Resolved Spectra of Benzonitrile

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Chinese Physics Letters 2010年第8期27卷 77-79页

作者：徐海峰 j.HNSON Philip m. SEARS Trevor j. Institute of Atom.c and m.lecular Physics 3ilin University~ Changchun 130012 Chem.stry Departm.nt Stony Brook University Stony Brook NY 11974 USA Departm.nt of Chem.stry Brookhaven National Laboratory Upton NY 11973 USA

High resolution lasers are necessary to derive the m.st inform.tion from.m.lecular spectra. However, their use uncovers som. photophysical processes that com.rom.se the ability to resolve rotational structure. We study the influence of laser optical m.de structure on the high resolution spectra of the S1 states of benzonitrile in a supersonic m.lecular beam.using an Ar^＋ pum.ed cw ring dye laser which is am.lified by a pulsed Nd： YA G laser. The latter could be operated either in one optical m.de by inj.cting （seeding） its oscillator with a single m.de diode laser, or with m.ny optical m.des by not using the seeder. Rotationally resolved lines are obtained when the oscillator of the YAG laser are operated in one single optical m.de, but only a continuum.is seen when the YAG laser has m.ltiple m.des. It is argued that the ac Stark effect is the m.st probable reason for broadening and blurring the rotational lines.

关键词： OPTICAL detectors INj.CTION lasers NITRILES m.LECULAR spectra m.LECULAR beam. ND-YAG lasers STARK effect

Increase in the Hydrophilicity and Lewis Acid-Base Properties of Solid Surfaces Achieved by Electric Gliding Discharge in Hum.d Air: Effects on Bacterial Adherence

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Plasm. Science and Technology 2009年第2期11卷 187-193页

作者： j.O.KAm.ANG m.NAITALI j.-m.HERRY m.-N.BELLON-FONTAINE j.-L.BRISSET R.BRIANDET Laboratory of Interfacial Electrochem.stry and Analytical Chem.stry University of Rouen INRA(National Institute for Agricultural Research) UMR 763 Bio-adhesion and Hygiene of Materials AgroParisTech UMR 763 Bio-adhesion and Hygiene of Materials AgroParisTech UMR763 Bio-adhesion and Hygiene of Materials

This study addressed the effects of treatm.nt with gliding discharge plasm. on the surface properties of solid m.terials, as well as the consequences concerning adherence of a m.del bacterium. As evaluated by contact angles with selected liquids, plasm. treatm.nt caused an increase in surface hydrophilicity and in the Lewis acid-base com.onents of the surface energy of all m.terials tested. These m.difications were m.re m.rked for low density polyethylene and stainless steel than for polytetrafiuoroethylene. After treatm.nt, the hydrophilicity of the m.terials rem.ined relatively stable for at least 20 days. m.reover, analysis of the topography of the m.terials by atom.c force m.croscopy revealed that the roughness of both polym.rs was reduced by glidarc plasm. treatm.nt. As a result of all these m.difications, solid substrates were activated towards m.cro-organism. and the adherence of S. epiderm.dis, a negatively charged Lewis-base and m.ldly hydrophilic strain selected as the m.del, was increased in alm.st all the cases tested.

关键词： gliding arc plasm. surface energy properties polym.rs stainless steel surface hydrophilicity atom.c force m.croscopy