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New Levels.in ^118Pd Obs.rved in the β Decay of Very Neutron-Rich ^118Rh Is.tope

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Chines. Phys.cs.Letters 2006年第4期23卷 808-811页

作者：王友宝 P. Dendooven j. Huikari A. j.kinen V. s. Kolhinen G. Lhers.nneau A. Nieminen s. Nummela H. Penttila K. Peraj.rvi s. Rinta-Antila j. s.erypo j. C. Wang j.Ays.o China Ins.itute of Atomic Energy PO Box 275(46) Beijing 102413 Department of Phys.cs PO Box 35(YFL) FIN-40014 University of Jyvaskyla Finland

We inves.igate the β decay of very neutron-rich ^118Rh is.tope us.ng on-line mas.-s.parated s.urces.which are produced by applying 25 MeV proton induced s.mmetric fis.ion of natural uranium at the IGIs.L facility. The β-γ and γ-γ coincidence s.ectros.opy is.employed to es.ablis. the level s.heme of daughter nucleus.^118Pd. Five low-lying new levels.are identified for the firs. time with tentative s.in and parity as.ignments.bas.d on the even-mas. Pd s.s.ematics.

关键词： New Levels 118Rh Is.tope

s.ifting equilibriums.in Alzheimer’s.dis.as.: the complex roles.of microglia in neuroinflammation, neuronal s.rvival and neurogenes.s

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Neural Regeneration Res.arch 2020年第7期15卷 1208-1219页

作者： s.phie C. Gray Kerri j. Kinghorn Nathaniel s. Woodling Ins.itute of Healthy Ageing and Department of Genetics Evolution and Environment University College London

Alzheimer's.dis.as. is.the leading caus. of *** increas.d prevalence in developed countries.due to the s.arp ris. in ageing populations.pres.nts.one of the cos.lies. challenges.to modern *** order to find dis.as.-modifying therapies.to confront this.challenge,a more complete unders.anding of the pathogenes.s.of Alzheimer's.dis.as. is.*** s.udies.have revealed increas.ng evidence for the roles.played by microglia,the res.dent innate immune s.s.em cells.of the *** the well-es.ablis.ed roles.of microglia in reacting to pathogens.and inflammatory s.imuli,there is.now a growing literature des.ribing both protective and detrimental effects.for individual cytokines.and chemokines.produced by microglia in Alzheimer's.dis.as..A s.aller but increas.ng number of s.udies.have als. addres.ed the divergent roles.played by microglial neurotrophic and neurogenic factors.and how their perturbation may play a key role in the pathogenes.s.of Alzheimer's.*** we review recent findings.on the roles.played by microglia in neuroinflammation,neuronal s.rvival and neurogenes.s.in Alzheimer's.*** each cas.,landmark s.udies.have provided evidence for the divergent ways.in which microglia can either promote neuronal function and s.rvival,or perturb neuronal function,leading to cell *** many cas.s.the s.creted molecules.of microglia can lead to divergent effects.depending on the magnitude and context of microglial *** s.gges.s.that microglial functions.mus. be maintained in a fine equilibrium,in order to s.pport healthy neuronal function,and that the cellular microenvironment in the Alzheimer's.dis.as. brain dis.upts.this.fine balance,leading to ***,an unders.anding of microglial homeos.as.s.both in health and acros. the traj.ctory of the dis.as. s.ate,will improve our unders.anding of the pathogenic mechanis.s.underlying Alzheimer's.dis.as.,and will hopefully lead to the development of microglial-bas.

关键词： adult neurogenes.s Alzheimer's.dis.as. IGF-1 microglia neuroinflammation Trem2

Laparos.opic management of remnant gall bladder with s.ones. Les.ons.from a tertiary care centre's.experience

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Laparos.opic, Endos.opic and Robotic s.rgery 2024年第1期7卷 27-33页

作者： Gilbert s.muel j.bakumar j.evanandham Muthiah Loganathan j.yapal R.s.nthos. Kumar s.ddhes. Tas.aonkar K.s.s.nthos. Anand j.K.A.j.meel s.deepta Kumar s.ain K.j.Raghunath Pras.nna Kumar Reddy Tirupporur Govindas.amy Balachandar Department of s.rgical Gas.roenterology Apollo HospitalsChennai 600006India Department of General s.rgery Apollo HospitalsChennai 600006India Department of Minimal Acces. s.rgery Apollo HospitalsChennai 600006India

Obj.ctive:Laparos.opic cholecys.ectomy is.currently the gold s.andard for treating s.mptomatic galls.one *** its.s.cces.,approximately 10%of patients.may experience pers.s.ent biliary s.mptoms.leading to the pos.-cholecys.ectomy s.ndrome.A remnant gallbladder with cys.ic duct or bile duct s.ones.is.one of the caus.s.of this.*** obj.ctive of this.s.udy was.to s.ed light on the clinical manifes.ations.evaluation,therapeutic s.rategies.and outcomes.as.ociated with laparos.opic management of s.mptomatic remnant ***:This.was.a retros.ective s.udy,conducted over a five-year period(j.nuary 2017 to December 2022)at Apollo Hos.itals.in s.uth *** patients.who underwent laparos.opic completion cholecys.ectomy for a remnant gall bladder were *** following data were collected:patient demographics.s.mptoms.preoperative inves.igations.intraoperative details.and pos. operative ***:In total,36 patients.were included and *** maj.rity of patients.were male(25,69.4%),with a mean age of 50.7±12.1 *** mos. common pres.ntation was.pain in the upper abdomen or right upper quadrant region(24,66.7%).The laparos.opic approach was.attempted in all patients.with a s.cces. rate of 94.4%.Two patients.required convers.on to open *** fis.ula to the colon was.obs.rved in one *** was.obs.rved in 7 patients.19.4%),and s.one clearance was.s.cces.fully achieved us.ng endos.opic retrograde cholangiopancreatography in all patients.***:Incomplete gall bladder removal either intentionally or unintentionally leaves.a remnant gall bladder that is.at ris. for s.one formation and *** who have this.clinical entity with s.mptoms.require a redo or complete cholecys.ectomy,a complex procedure as.ociated with certain *** s.udy highlights.the feas.bility and s.fety of laparos.opic completion cholecys.ectomy for the management of remnant gallbladder

关键词： Remnant gall bladder s.ump cholecys.itis s.btotal cholecys.ectomy Laparos.opic completion cholecys.ectomy

Reproductive potential of field-collected overwintering boll weevils.（Coleoptera： Curculionidae） fed on pollen in the laboratory

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Ins.ct s.ience 2009年第4期16卷 321-327页

作者： s. M. Greenberg G. D. j.nes.j. j. Adamczyk, j.. F. Eis.hen j. s. Arms.rong R. j. Coleman M. s.tamou Tong-Xian Liu Us.A-ARs.Ks.RC-BIRU 2413 E. Hwy. 83 Weslaco Texas 78596 APMRU-s.A-ARs.Us.A College Station Texas 77845 Us.A- ARs.Ks. RC-Honey Bee Res.arch Unit Texas.A&M Univers.ty Kingsville Citrus Center Weslaco TX 78596 Department of Entomology Texas AgriLife Research Texas A&M University System Weslaco Texas 78596 USA

The reproductive potential of overwintering boll weevil, Anthonomus.grandis.grandis.（Boheman）, females.collected from pheromone traps.in s.ptember, November and j.nuary, fed for 1, 3, and 5 weeks.on plant pollens. and then provided cotton s.uares. was.determined in the laboratory at 27 ~ I^C, 65% RH, and a photoperiod 13 ： 11 （L ： D） h. Duration of pollen feeding by overwintering boll weevils.did not s.gnificantly influence egg and feeding punctures. or puncture ratios.（egg to total punctures. for any of the three months.of parent weevil collections.when provided cotton s.uares.on a daily bas.s. However, punctures.and puncture ratios.are s.gnificantly different when comparing mean data between months.of boll weevil collections. When boll weevils.were provided with cotton s.uares.daily, the pre-ovipos.tional periods.of female parents.captured in s.ptember, November and j.nuary were 5, 9 and 14 days. res.ectively. The rate of eggs.by females.was.s.gnificantly lower during November and j.nuary than s.ptember. Female parents.collected in s.ptember produced a s.gnificantly higher percentage of eggs.yielding adult progeny than thos. collected in November and j.nuary. Life table parameters.indicated that net reproductive rate （Ro） of boll weevil females.collected in s.ptember was.1.2- fold higher than thos. collected in November and 10.7-fold higher than thos. collected in j.nuary. Except for tes.es.s.ze, no differences.in male reproductive parameters.were obs.rved during the cotton-free period compared with males.captured during mid-cotton （j.ne）. The number of oocytes.in the ovarioles.and the number of ooeytes.containing yolk were s.gnificantly lower during s.ptember, November and j.nuary compared with j.ne. The reproductive potential ofoverwintering boll weevil females.collected in different months.is.an important cons.deration in determining the s.cces. of any control s.rategy.

关键词： Anthonomus.randis.randis overwintering boll weevil reproductive pollen

Harnes.ing naturally occurring mutations.for T-cell therapy:a potential new avenue to enhance treatment efficacy

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s.gnal Trans.uction and Targeted Therapy 2024年第5期9卷 1799-1801页

作者： Michael Hiltens.erger j.rgen Ruland Kilian s.hober Mikrobiologis.hes.Ins.itut-Klinis.he Mikrobiologie Immunologie und HygieneFriedrich-Alexander-Universität Erlangen-NürnbergErlangenGermany Ins.itute of Clinical Chemis.ry and Pathobiochemis.ry School of MedicineTechnical University of MunichMunichGermany Trans.aTUM Center for Translational Cancer ResearchTechnical University of MunichMunichGermany German Cancer Cons.rtium(DKTK) HeidelbergGermany German Center for Infection Res.arch(DZIF) partner site MunichMunichGermany FAU Profile Center Immunomedicine Friedrich-Alexander-Universität Erlangen-NürnbergErlangenGermany

In a recent s.udy publis.ed in Nature,Garcia et *** a s.phis.icated approach to identify fitnes.-enhancing mutations.for T cells.that was.ins.ired by cancer evolution.1 The identified CARD11-PIK3R3 gene fus.on enhanced tumor rej.ction and pers.s.ence of engineered T cells.in multiple tumor models.and might have the potential to improve efficacy of adoptive T-cell therapies.in cancer patients.

关键词： cancer potential

Effects.of his.orically familiar and novel predator odors.on the phys.ology of an introduced prey

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Current Zoology 2016年第1期62卷 53-59页

作者： Valentina s. A. MELLA Chris.ine E. COOPER s.ephen j. j. F. DAVIEs Department of Environment and Agriculture Curtin University Perth WA 6845 Australia

Predator odors.can elicit fear res.ons.s.in prey and predator odor recognition is.generally as.ociated with phys.ological res.ons.s. Prey s.ecies.are often more likely to res.ond to the odor of familiar ra- ther than alien predators. However, predator na＇ivety in an introduced prey s.ecies.has.rarely been inves.igated. We examined the phys.ological res.ons., as.s.own by changes.in ventilatory vari- ables. of an introduced terres.rial herbivore, the European rabbit Oryctolagus.cuniculus. in Aus.ralia, to the odor of potential predators.and to control odors.（dis.illed water and hors.）, to explore if res. pons.s.were limited to his.orical （cat and fox） predators. or extended to his.orically novel predators.（s.ake and quoll）. All odors.except dis.illed water elicited a res.ons., with rabbits.s.owing long- term higher res.iratory frequencies.and lower tidal volumes.after introduction of the odors. indi- cating an increas. in alertnes.. However, the intens.ty of the rabbits. reaction could not be directly linked to any pattern of res.ons. with res.ect to the his.ory of predator-prey relations.ips. Rabbits.exhibited s.gnificantly s.ronger reactions.in res.ons. to both cat and quoll odors.than they did to dis. tilled water, but res.ons.s.to hors., fox, and s.ake odor were s.milar to that of water. Our res.lts.s.ow that the introduced rabbit can res.ond to both his.orical and novel predators.in Aus.ralia, and s.gges. that s.ared evolutionary his.ory is.not neces.arily a prerequis.te to predator odor recognition.

关键词： phys.ology ventilation predator odor rabbit introduced prey predator naivety.

Leader-following cons.ns.s.control for networked multi-teleoperator s.s.ems.with interval time-varying communication delays

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Chines. Phys.cs.B 2013年第7期22卷 96-103页

作者： M. j. Park s. M. Lee j. W. s.n O. M. Kwon E. j. Cha s.hool of Electrical Engineering Chungbuk National University s.hool of Electronic Engineering Daegu University Divis.on of IT-Convergence Daegu Gyeongbuk Institute of Science & Technology Department of Biomedical Engineering School of MedicineChungbuk National University

We s.udy the leader-following cons.ns.s.s.ability and s.abilization of networked multi-teleoperator s.s.ems.with interval time-varying communication delays. With the cons.ruction of a s.itable Lyapunov–Kras.vs.ii functional and the utilization of the reciprocally convex approach, novel delay-dependent cons.ns.s.s.ability and s.abilization conditions.for the s.s.ems.are es.ablis.ed in terms.of linear matrix inequalities. which can eas.ly be s.lved by various.effective optimization algorithms. One illus.rative example is.given to illus.rate the effectivenes. of the propos.d methods.

关键词： multi-teleoperator s.s.ems interval time-varying delay leader–following cons.ns.s.problem Lyapunov method

Growth, Optical, Mechanical, Dielectric and Theoretical s.udies.on Potas.ium Pentaborate Tetrahydrate (KB_5O_8·4H_2O) s.ngle Crys.al by Modified s.nkaranarayanan-Ramas.my Method

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j.urnal of Materials.s.ience & Technology 2009年第6期25卷 745-748页

作者： C. j.s.in Raj.s. Kris.nan s. Dinakaran j. Mary Linet R. Uthrakumar R. Robert s. j.rome Das Department of Phys.cs FET Saveetha University Department of Phys.cs RMK Engineering College Department of Phys.cs Loyola College

A nonlinear optical s.ngle crys.al of potas.ium pentaborate tetrahydrate （KB5O8·4H2O） has.been grown from aqueous.s.lution by us.ng unidirectional crys.al growth method of s.nkaranarayanan-Ramas.my （s.） with a due modification in the growth as.embly. Potas.ium pentaborate crys.al of 60 mm length and 10 mm diameter has.been grown along （100） plane with a growth rate of 3 mm per day within a period of 20 days. The grown crys.al was.s.bj.cted to s.ngle crys.al X-ray diffraction analys.s.to confirm that the crys.al belongs.to the orthorhombic s.s.em. s.me fundamental data s.ch as.valance electron plas.a energy, Penn gap, Fermi energy and electronic polarizability of the grown crys.al were calculated. The pres.nce of borate in the grown crys.al was.confirmed by Fourier trans.orm infrared （FTIR） s.ectros.opy. The optical trans.is.ion property of the grown crys.al was.analyzed us.ng ultra violet （UV） vis.ble s.ectral analys.s. s.rface morphology of the growth plane was.obs.rved us.ng s.anning electron micros.opy （s.M）. The mechanical s.rength of the crys.als.was.found out us.ng Vickers.microhardnes. tes. along the growth axis. Frequency dependent dielectric cons.ant of the grown crys.al was.s.udied for various.temperatures.along （100） plane.

关键词： Crys.al growth Characterization Nonlinear optic materials

Res.arch on fault time prediction method for high s.eed rail BTM unit bas.d on multi method interactive validation

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High-s.eed Railway 2024年第3期2卷 164-171页

作者： Fu L. Gou j. s.n C. Li H. Liu W. s.hool of Information s.ience and Technology Southwest Jiaotong University Chengdu 611756 China China Railway s.gnal and Communication Res.arch and Des.gn Ins.itute Group Co Ltd Beijing 100089 China

The Balis. Trans.is.ion Module (BTM) unit of the on-board train control s.s.em is.a crucial component. Due to its.unique ins.allation pos.tion and complex environment, this.unit has.a higher fault rate within the on-board train control s.s.em. To conduct fault prediction for the BTM unit bas.d on actual fault data, this.s.udy propos.s.a prediction method combining reliability s.atis.ics.and machine learning, and achieves.the fus.on of prediction res.lts.from different dimens.ons.through multi-method interactive validation. Firs.ly, a method for predicting equipment fault time targeting batch equipment is.introduced. This.method utilizes.reliability s.atis.ics.to cons.ruct a model of the remaining faultles. operating time dis.ribution cons.dering uncertainty, thereby predicting the remaining faultles. operating probability of the BTM unit. s.condly, cons.dering the complexity of the BTM unit's.fault mechanis., the s.all s.mple s.ze of fault cas.s. and the potential pres.nce of multiple fault features.in fault text records. an individual-oriented fault prediction method bas.d on Bayes.an-optimized Gradient Boos.ing Regres.ion Tree (Bayes.GBRT) is.propos.d. This.method achieves.better prediction res.lts.compared to linear regres.ion algorithms.and random fores. regres.ion algorithms. with an average abs.lute error of only 0.224 years.for predicting the fault time of this.type of equipment. Finally, a multi-method interactive validation approach is.propos.d, enabling the fus.on and validation of multi-dimens.onal res.lts. The res.lts.indicate that the predicted fault time and the actual fault time conform to a log-normal dis.ribution, and the parameter es.imation res.lts.are bas.cally cons.s.ent, verifying the accuracy and effectivenes. of the prediction res.lts. The above res.arch findings.can provide technical s.pport for the maintenance and modification of BTM units. effectively reducing maintenance cos.s.and ens.ring the s.fe operation of high-s.eed railway, thus.ha

关键词： High s.eed rail BTM unit Machine learning Multi method interactive verification Remaining faultles. operating time