检索结果-南通市图书馆

海洋地质 2013年第1期29卷 31-32页

作者： George j. mORIDIS j.hoon KIm Craig m. FREEmAN

本文通过数值模拟分析了页岩和致密砂岩这两种类型的裂缝型致密气藏的流一固耦合机制和过程。数学模型包括基于达西定律的多相流方程和有关储层流体热物理性质的准确描述。

关键词：致密气藏耦合机制裂缝型页岩数值模拟分析热物理性质致密砂岩储层流体

口服凝血酶抑制剂预防脑卒中试验(SPORTIF)中非瓣膜性心房颤动女性患者的抗凝治疗

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（心脏病学分册） 2007年第1期3卷 52-53页

作者： Gomberg-maitland m. Feyzi j. 吴晓燕 Department of medicine University of Chicago Hospitals University of Chicago 5841 SMaryland Avenue Chicago IL 60637 United States

目的:女性心房颤动(AF)患者脑卒中的风险高于男性。华法林可预防脑卒中,但是由治疗引起的出血在女性中比男性中更多见。方法与结果:SPORTIF III试验(公开标记,n=3410)和SPORTIF V试验(双盲,n=3922)共纳入2257例伴有至少一个脑卒中危险... 详细信息

目的:女性心房颤动(AF)患者脑卒中的风险高于男性。华法林可预防脑卒中,但是由治疗引起的出血在女性中比男性中更多见。方法与结果:SPORTIF III试验(公开标记,n=3410)和SPORTIF V试验(双盲,n=3922)共纳入2257例伴有至少一个脑卒中危险因素的女性AF患者,受试者被随机分配到华法林治疗组[目标国际标准化比值(INR)2.0～3.0]或希美加群组(36m g,2次/d)。主要终点事件为所有脑卒中(包括缺血性和出血性)和全身性栓塞事件。女性患者的平均年龄较男性大(73.4±8.0岁vs69.8±9.0岁,P<0.0001)。

关键词：预防脑卒中 SPORTIF 脑卒中危险因素凝血酶抑制剂全身性栓塞国际标准化比值心房颤动加群

Necklaces of PT-symmetric dimers

在线全文

学校读者我要写书评

暂无评论

Photonics Research 2018年第5期6卷 I0012-I0018页

作者： D.j.NODAL STEVENS BENj.mIN j.RAmILLO AVILA B.m.RODRIGUEZ-LARA Tecnologico de monterrey Escuela de Ingenieria y CienciasAve.Eugenio Garza Sada 2501MonterreyN.L.64849Mexico CONACYT-Instituto Nacional de Astroffsica Optica y ElectronicaCalle Luis Enrique Erro No.1Sta.Ma.TonantzintlaPue.CP 72840Mexico Instituto Nacional de Astroffsica Optica y ElectronicaCalle Luis Enrique Erro No.1Sta.Ma.TonantzintlaPue.CP 72840Mexico

We study light propagation through cyclic arrays, composed by copies of a given PT-symmetric dimer, using a group theoretical approach and finite dement modeling. The theoretical mode-coupling analysis suggests the use of these devices as output port replicators where the dynamics is controlled by the impinging light field. This is confirmed in good agreement with finite element propagation in an experimentally feasible necklace of passive PT-symmetric dimers constructed from lossy and lossless waveguides.

关键词： Necklaces PT-symmetric dimers

在线全文

学校读者我要写书评

暂无评论

妄想和幻觉与阿尔茨海默病的不良预后相关

世界核心医学期刊文摘(神经病学分册) 2006年第2期 16-17页

作者： Scarmeas N. Brandt j. Albert m. 郭俊 Columbia University medical Center Presbyterian Hospital 622 W 168th St New York NY 10032 United States.Dr

Background: Delusions and hallucinations are common in Alzheimer disease (AD) and there are conflicting reports regarding their ability to predict cognitive decline, functional decline, and institutionalization. According to all previous literature, they are not associated with mortality. Obj.ctive: To examine whethe r the presence of delusions or hallucinations has predictive value for important outcomes in AD. Design, Setting, and Participants: A total of 456 patients with AD at early stages (mean Folstein mini-mental State Examination [mmSE] score of 21 of 30 at entry) were recruited and followed up semiannually for up to 14 years (mean, 4.5 years) in 5 university-based AD centers in the United States and Europe. Using the Columbia University Scale for Psychopathology in AD (administered every 6 months, for a total of 3266 visit-assessments, average of 7.2 per patient), the presence of delusions and hallucinations was extracted and examined as time-dependent predictors in Cox models. The models controlled for cohort effect, recruitment center, informant status, sex, age, education, a comorbidity index, baseline cognitive and baseline functional performance, behavioral sympt oms, and use of neuroleptics and cholinesterase inhibitors. main Outcome measure s: Cognitive (Columbia mmSE score of ≤20/57 [approximate Folstein mmSE score o f ≤10/30]), functional (Blessed Dementia Rating Scale [parts I and II] score of ≥10), institutionalization equivalent index, and death. Results: During the full course of follow-up, 38%of patients reached the cognitive, 41%the functiona l, 54%the institutionalization, and 49%the mortality end point. Delusions were noted for 34%of patients at baseline and 70%at any evaluation. Their presence was associated with increased risk for cognitive (risk ratio [RR], 1.50; 95%confidence interval [CI], 1.07-2.08) and functional decline (RR, 1.41; 95%CI, 1.02-1.94). Hallucinations were present in 7%of patients at initial visit and in 33%at any visit

关键词：阿尔茨海默病习惯化患者 AD 认知功能机能衰退幻觉感觉障碍

超声内镜检查与螺旋CT用于胃癌局部区域分期的对比研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2005年第1期1卷 23-24页

作者： Polkowski m. Palucki j. Wronska E. 李康 Department of Gastroenterology Med.Center for Postgrad.EducationInstitute of OncologyRoentgena 502-781 WarsawPoland

Background and Study Aims: Endosonography(EUS) has been shown to be more accurate than incremental computed tomography(CT) in the local (T) and regional (N) staging of gastric carcinoma; however, EUS has never been compared with helical CT (HCT). The fifth edition of the TNm classification changed the guidelines for N-staging of gastric carcinoma. The accuracy of imaging methods in this new system remains *** and methods: Staging accuracy of EUS and HCT were compared prospectively with pathological or intraoperative findings in 88 gastric carcinoma patients. Staging was done according to the fourth and fifth editions of the TNm classification. EUS was done with a radial echo endoscope,and HCT with a scanner with two rows of detectors (two-phase contrast-enhanced scanning of a water-filled stomach). Results:The T-staging accuracy of EUS (63% ,CI 52-73% )was superior to the accuracy of HCT(44% , CI 34-55% ;P=0.021). N-staging accuracy of both methods was similar when the fourth edition of the TNm classification was used (EUS 47% , CI 34-60% ; HCT 52% , CI 38-65% ). However, HCT was more accurate than EUS when the fifth edition of the classification was applied(EUS 30% , CI 18-43% , HCT 47% , CI 34-60% ; P = 0.044).The accuracy of detection of lymph node metastases was similar for both methods (EUS 67 % , CI 54-78% ; HCT 77% , CI 64-86% ). Conclusions: EUS is more accurate than HCT in the T-staging of gastric carcinoma. Both methods are comparable for N-staging, when this is done according to the older, fourth edition of the TNm classification. If the fifth edition is used,EUS is less accurate than HCT.

关键词：超声内镜检查扇形扫描淋巴结转移增强扫描

Natatanuran frogs used the Indian Plate to step-stone disperse and radiate across the Indian Ocean

在线全文

学校读者我要写书评

暂无评论

National Science Review 2019年第1期6卷 10-14页

作者： Zhi-Yong Yuan Bao-Lin Zhang Christopher j.Raxworthy David W.Weisrock Paul m.Hime j.e-Qiong j.n Emily m.Lemmon Alan R.Lemmon Sean D.Holland michelle L.Kortyna Wei-Wei Zhou min-Sheng Peng j.ng Che Elizabeth Prendini State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Key Laboratory for Forest Resources Conservation and Utilization in the Southwest mountains of China Ministry of Education Southwest Forestry University Kunming College of Life Science University of Chinese Academy of Sciences Department of Herpetology American Museum of Natural History Department of Biology University of Kentucky Biodiversity Institute University of Kansas Southeast Asia Biodiversity Research Institute Chinese Academy of Sciences Department of Biological Science Florida State University Department of Scientific Computing Florida State University Sino-Africa j.int Research Center Chinese Academy of Sciences Center for Excellence in Animal Evolution andGenetics Chinese Academy of Sciences

Investigating the evolutionary history of widespread higher taxa, subj.cted to multiple tectonic events, can provide evidence for or against various palaeogeographical models of early Earth history [1,2]. Contemporary biotic distributions have been strongly influenced by events associated with the breakup of Gondwana into present-day Africa,Antarctica, Australia, South America,madagascar and India, during the Late mesozoic and Early Palaeogene [2]. The fragmentation of Gondwana and subsequent tectonic drift ultimately allowed biotic exchanges between Laurasia and Gondwana [2,3], influencing the global distributions of many taxa.

关键词： In Natatanuran frogs used the Indian Plate to step-stone disperse and radiate across the Indian Ocean

The Effects of Sample matrices on Immunoassays to Detect microcystin-LR in Water

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

j.urnal of Environmental Protection 2012年第10期3卷 1275-1285页

作者： Armah A. de la Cruz Trevor j. Lynch Dionysios D. Dionysiou Office of Research and Development The US Environmental Protection Agency Cincinnati USA School of Energy Environmental Biological and Medical Engineering University of Cincinnati Cincinnati USA

Immunoassays are widely used biochemical techniques to detect microcystins in environmental samples. The use of immunoassays for the detection of microcystins is vulnerable to matrix components and other interferents. This study is an evaluation of the effects of interfering substances commonly found in drinking and ambient water samples using commercially-available immunoassay kits for microcystin toxins. The microplate and strip test immunoassay formats were tested in the study. For the microplate ELISA, the following were found to inhibit microcystin-LR (mC-LR) detection: 250 μg/mL Ca2+ or mg2+, 0.01% ascorbic acid, 0.1% EDTA chelating agent, 0.05 m glycine-HCl, pH 3. The following exhibited no effect: sodium chloride (NaCl, 1% to 4%) and sodium thiosulfate (0.001% and 0.01%), 0.01 to 0.1 m phosphate buffers (PB), pH 7 and 0.067 m PB at pH 5, 6, 7 and 8. Overall, up to 50 μg/mL of standard and reference natural organic matter (NOm) from various sources did not interfere in the assay system (without mC-LR) but diminished the detection of mC-LR at varying degrees. This is the first study evaluating standard and reference humic and fulvic acids from various sources in immunoassays for microcystins. The strip test also showed variable effects on mC-LR detection in the presence of NOm. This assay format was also sensitive to varying pHs and ionic strengths. mC-LR binding was inhibited at low pH (0.05 m glycine-HCl, pH 3), whereas, 0.067 m PB with pH 6, 7 and 8 can yield false positive results. Lower ionic strength of 0.01 m PB, pH 7 showed no interference in mC-LR binding whereas higher ionic strengths can interfere with mC-LR detection. NaCl at 3% and 4% can interfere with the analysis giving false positive results. mg2+ at 50 and 250 μg/mL showed no effect on the analysis while the same concentration of Ca2+ can yield false positive results. The performance in marine, brackish and hard waters should be tested given the potential sensitivity to salinity. Results of t

关键词： microcystin Immunoassay Sample matrix Natural Organic matter

应用图像卷积神经网络预测大脑年龄诠释早产儿神经发育轨迹

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2024年第4期 500-500页

作者： m.T.Liu m.H.Lu S.Y.Kim H.j.Lee B.A.Duffy S.Y.Yuan 杨程

摘要目的婴儿大脑在妊娠晚期会发生显著的形态变化。探讨应用图像卷积网络（GCN）根据孕晚期胎儿皮质形态预测的大脑年龄（PBA）与产后异常和神经发育结局是否存

关键词：

苏格兰皮肤黑色素瘤家族的CDKN2A突变:32个新发现家族的研究结果

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（皮肤病学分册） 2006年第3期2卷 36-37页

作者： Lang j. Boxerm. macKie R.m. 焦婷 Duncan Guthrie Institute of medical Genetics Royal Hospital for Sick Children University of Glasgow Glasgow United Kingdom

Background: Up to 5% of patientswith melanoma have a family history of a first-degree relative also being affected. Obj.ctives: To study such families for germline mutations, to help clarify the gene-environment interaction in melanoma aetiology. methods: Thirty-two families in Scotland with melanoma in two or more first-degree relatives are reported for the first time. Peripheral blood DNA was extracted, and denaturing high-performance liquid chromatography analysis performed on exons 1 α and 2 of the CDKN2A gene and their splice j.nctions. The coding sequences and splice j.nctions of these exons were sequenced in all samples as confirmation of the chromatographic pattern observed. Results: Seven of the 32 melanoma families (22% ) have CDKN2A mutations. One mutation, H83N, which has not previously been described in melanoma families, was found in one family. In addition, two families have R112G mutations, one family has a G67R mutation, one has an exon 1 α 24-bp duplication where bases 9- 32 are duplicated between bases 32 and 33, and two families have m53I mutations, bringing the total of known Scottish families with the m53I mutation to six. Conclusions: This study brings the total of Scottish families investigated for germlinemutations to 48, and strongly suggests that the m53I mutation originated in Scotland.

关键词： CDKN2A基因皮肤黑色素瘤种系突变家族史苏格兰变性高效液相色谱法新发外周血DNA 一级亲属基因-环境

On the Late Hydrothermal Tungsten Deposits of Haiyangshan mountain, Kuangsi

在线全文

学校读者我要写书评

暂无评论

地质学报 1949年第Z1期 135-144页

作者： C. K.KUNG and j. H. CHANG (Geological Survey of China)

INTRODUCTIONThe Haiyangshan mountain trending in the NNE-SSW direction is situated between the Hsiangan and Kuanyang cites in NE Kuangsi. The principal mines are located on the E slope at about 200 m above Sanyutsun, a village nearly 25 km NW of Kuanyang. The tungsten mineralization in the region is confined chiefly to the quartz veins which were formed by the ore-bearing solutions along the fractures in the granodiorite shortly after its consolidation.

关键词： Kuangsi On the Late Hydrothermal Tungsten Deposits of Haiyangshan mountain