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Optimization of N18 Zirconium Alloy for Fuel Cladding of Water Reactors

j.urnal of Materials Science & Technology 2012年第7期28卷 606-613页

作者： B.X. Zhou M. Y. Yao Z.K. Li X.M. Wang j. zhoua C.S. Long Q. Liu B.F. Luan Laboratory for Mierostructures Shanghai University Shanghai 200444 China Institute of Materials Shanghai University Shaxighai 200072 China Northwest Institute for Non-ferrous Metal Research Xian 721014 China Key Laboratory for Nuclear Fuel and Materials Nuclear Power Institute of China Chengdu 610041 China College of Material Science and Engineering Chongqing University Chongqing 400044 China

In order to optimize the microstructure and composition of N18 zirconium alloy （Zr-1Sn-0.35Nb-0.35Fe-0.1Cr, in mass fraction, %）, which was developed in China in 1990s, the effect of microstructure and composition variation on the corrosion resistance of the N18 alloy has been investigated. The autoclave corrosion tests were carried out in super heated steam at 400 ~C/10.3 MPa, in deionized water or lithiated water with 0.01 mol/L LiOH at 360 ~C/18.6 MPa. The exposure time lasted for 300-550 days according to the test temperature. The results show that the microstructure with a fine and uniform distribution of second phase particles （SPPs）, and the decrease of Sn content from 1% （in mass fraction, the same as follows） to 0.8% are of benefit to improving the corrosion resistance; It is detrimental to the corrosion resistance if no Cr addition. The addition of Nb content with upper limit （0.35%） is beneficial to improving the corrosion resistance. The addition of Cu less than 0.1% shows no remarkable influence upon the corrosion resistance for N18 alloy. Comparing the corrosion resistance of the optimized N18 with other commercial zirconium alloys, such as Zircaloy-4, ZIRLO, E635 and Ell0, the former shows superior corrosion resistance in all autoclave testing conditions mentioned above. Although the data of the corrosion resistance as fuel cladding for high burn-up has not been obtained yet, it is believed that the optimized N18 alloy is promising for the candidate of fuel cladding materials as high burn-up fuel assemblies. Based on the theory that the microstructural evolution of oxide layer during corrosion process will affect the corrosion resistance of zirconium alloys, the improvement of corrosion resistance of the N18 alloy by obtaining the microstructure with nano-size and uniform distribution of SPPs, and by decreasing the content of Sn and maintaining the content of Cr is discussed.

关键词： Zirconium alloys Corrosion resistance Composition variation Microstructure

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The Criterions of Minimum Number of Arrayed Waveguides for the Design of Arrayed Waveguide Gratings

The Criterions of Minimum Number of Arrayed Waveguides for t...

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20th Congress of the International Commission for Optics

作者： j. zhoua Y. K. Zhanga Z. H. j.ab G. L. Dinga H. B. Yaoaa. Department of Optical Engineering School of Mechanical Engineering j.angsu University Zhenj.ang 212013 P. R. China b. School of Information Science & Engineering Xinj.ang University Urumqi 830000 P. R. China

The criterions for determining the minimum number of arrayed waveguides are presented using the design theory of arrayed waveguide gratings (AWGs) and Fraunhofer diffraction principle for the optimal

关键词： Arrayed waveguide gratings Beam propagation method Fraunhofer diffraction

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Enhanced tensile properties in a Mg-6Gd-3Y-0.5Zr alloy due to hot isostatic pressing(HIP)

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j.urnal of Materials Science & Technology 2019年第9期35卷 1860-1868页

作者： B. zhoua D.Wu R.S.Chen En-hou Han The Group of Magnesium Alloys and Their applications Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China

Hot isostatic pressing (HIP) was applied to Mg-6Gd-3Y-0.5Zr (GW63) alloy to reduce shrinkage porosity, thus, to enhance the integrity and reliability of castings. During HIP process, shrinkage porosity was closed by grain compatible deformation and subsequent diffusion across the bonding interface. The amount of initial shrinkage porosity was the key factor for shrinkage porosity closure. HIP was testified to be effective on shrinkage porosity reduction in GW63 alloy due to its relatively narrow solidification range and resultant low content of initial shrinkage porosity in most sections, leading to higher tensile properties both in as-cast and cast-T6 condition. The improvement in tensile properties was mainly because of shrinkage porosity reduction and resultant effective rare-earth (RE) elements homogenization and precipitation strengthening.

关键词： Hot isostatic pressing Mg-Gd-Y-Zr Shrinkage porosity reduction Tensile properties

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Crystal structure of a bacterial homolog to human lysosomal transporter,spinster

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Science Bulletin 2019年第18期64卷 1310-1317页

作者： Fu zhoua Deqiang Yao Bing Rao Li Zhang Wang Nie Yan Zou j.e Zhao Yu Cao CAS Center for Excellence on Molecular Cell Science Institute of Biochemistry and Cell BiologyChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 201210China Institute of Precision Medicine The Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200125China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China Department of Orthopaedics Shanghai Key Laboratory of Orthopaedic ImplantShanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China

Lysosomes break down various biomolecules and spinster is one of the maj.r efflux carriers removing degradation products from lysosomal lumen to keep it in healthy size and proper *** it is well established that a dysfunctional spinster will cause enlarged lysosomes and in turn lead to developmental defects and abnormal behavior in animals,little was known about the transportation mechanism and substrate specificity of ***,we report a crystal structure of spinster homolog from Hyphomonas neptunium,HnSPNS,in its inward-facing conformation with and without substrate *** is crystallized in a monomer and a substrate-binding cavity was formed in the center of its transmembrane helices.A blob of electron density corresponding to its substrate was found in the cavity near a conserved residue,R42,which is locked in position by the interactions with conserved residues E129 and *** results suggest that human spinster serves as a transporter translocating negativelycharged lipophilic small molecules and E129 might serve as a switch to control the conformational change via its protonation-deprotonation cycle.

关键词： Maj.r facilitator superfamily Transporter Spinster Membrane protein

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Effects of support pore size on new Cs_(2.5)H_(0.5)PW_(12)O_(40)/SiO_2 catalysts for the ring-opening polymerization of tetrahydrofuran

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Chinese Chemical Letters 2009年第3期20卷 344-347页

作者： Xue Mei Liao Wei Chu Yang Li FU Dong zhoua Shi Zhong Luo Department of Chemical Engineering Sichuan University Chengdu 610065 China Research Institute of Natural Gas Technology Petrochina Southwest Oil and Gas Field Company Chengdu 610213 China

Mesoporous silica supported Cs2.5H0.5PW12O40 catalysts were prepared by impregnation method, and several silica supports with different pore size were utilized. N2 adsorption, XRD and ICP-AES techniques were utilized to characterize the silica supports and catalysts. XRD results showed that the dispersion of Cs2.5H0.5PW12 was better for the silica support with larger pore size. The catalytic activity results showed that the pore size played important role on the catalyst activity and the molecular weight of PTHF. When Cs2.5H0.5PW12O40 was dispersed on larger pore size silica support, the catalysts showed good performances for the synthesis of PTHE The molecular weight of PTHF product on the sample in which Cs2.5H0.5PW12O40 was dispersed on larger pore support was higher than that on the catalyst with smaller pore support. The leaching amounts of the active components for the supported Cs2.5H0.5PW12O40 catalysts were much lower. After five reaction cycles, there were still good activities and stabilities for the supported Cs2.5H0.5PW12O40 catalysts with larger pore silica supports. These results were much better than those of the supported heteropolyacid H3PW12O40 catalyst.

关键词： PTHF synthesis Cs2.5H0.5PW12O40 catalysts Mesoporous silica Pore size Stability

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Implementing an innovated liver ex-situ machine perfusion technology:The 2018 j.int International Congress of ILTS,ELITA and LICAGE

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Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 283-285页

作者： j.n-j.n j.a j.an-Hui Li Hai-Yang Xie Lin zhoua Shu-Sen Zheng Division of Hepatobiliary Pancreatic Surgery First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Key Laboratory of Combined Multi-Organ Transplantation Ministry of Public HealthFirst Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

The 2018 j.int International Congress of ILTS,ELITA and LICAGE were held in Lisbon,Portugal on May 23–26,*** exciting and innovative program brought together 1144 experts in liver transplantation(LT)such as surgeons,physicians or basic scientists from 61 *** presentations included 110 invited speakers,181 oral presentations,and 545 *** editorial highlights some of the most innovative and impactful presentations in

关键词： NMP WIT DCD Implementing an innovated liver ex-situ machine perfusion technology:The 2018 j.int International Congress of ILTS,ELITA and LICAGE

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Dendritic nanomedicine enhances chemoimmunotherapy by disturbing metabolism of cancer-associated fibroblasts for deep penetration and activating function of immune cells

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3680-3696页

作者： Yunkun Li Xiaoding Shen Haitao Ding Yuxin Zhang Dayi Pan Liping Su Yahui Wu Zaixiang Fang j.e zhoua Qiyong Gong Kui Luo Department of Radiology Huaxi MR Research Center(HMRRC)Frontiers Science Center for Disease-Related Molecular NetworkState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Functional and Molecular Imaging Key Laboratory of Sichuan Province and Research Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu 610041China Department of Radiology West China Xiamen Hospital of Sichuan UniversityXiamen 361021China

Inefficient drug penetration hurdled by the stroma in the tumor tissue leads to a diminished therapeutic effect for drugs and a reduced infiltration level of immune ***,we constructed a PEGylated dendritic epirubicin(Epi)prodrug(Epi-P4D)to regulate the metabolism of cancer-associated fibroblasts(CAFs),thus enhancing Epi penetration into both multicellular tumor spheroids(MTSs)and tumor tissues in mouse colon cancer(CT26),mouse breast cancer(4T1)and human breast cancer(MDA-MB-231)*** cytotoxicity against CT26 MTSs and remarkable antitumor efficacy of Epi-P4D were ascribed to reduced fibronectin,α-SMA,and collagen ***,thinning of the tumor tissue stroma and efficient eradication of tumor cells promoted the immunogenic cell death effect for dendritic cell(DC)maturation and subsequent immune activation,including elevating the CD4^(+)T cell population,reducing CD4^(+)and CD8^(+)T cell hyperactivation and exhaustion,and amplifying the natural killer(NK)cell proportion and effectively activating *** a result,this dendritic nanomedicine thinned the stroma of tumor tissues to enhance drug penetration and facilitate immune cell infiltration for elevated antitumor efficacy.

关键词： Dendritic prodrug Enhanced penetration Metabolic intervention Cancer-associated fibroblasts Immunogenic cell death Chemotherapy Immunotherapy Immune microenvironment reconstitution

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托市政策下我国粮食价格波动成因分析

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华南农业大学学报（社会科学版） 2018年第1期17卷 27-36页

作者：周洲石奇南京财经大学粮食安全与战略研究中心江苏南京210046 南京财经大学经济学院江苏南京210046

基于2003—2014年稻谷、小麦和玉米主产区的面板数据对托市政策下我国粮食价格波动的成因进行了实证分析。研究发现,生产成本、通胀水平以及粮食价格支持政策的实施,对我国粮食价格具有显著的正向影响,且影响程度较大。竞争作物价格对... 详细信息

基于2003—2014年稻谷、小麦和玉米主产区的面板数据对托市政策下我国粮食价格波动的成因进行了实证分析。研究发现,生产成本、通胀水平以及粮食价格支持政策的实施,对我国粮食价格具有显著的正向影响,且影响程度较大。竞争作物价格对粮食价格具有显著的正向影响,但影响程度较小。居民收入对不同粮食品种价格的影响方向存在差异,对小麦和玉米价格具有显著的正向影响,对稻谷价格具有显著的负向影响。进口对稻谷价格具有负向影响,与小麦和玉米价格具有正相关关系。上一期价格对当期稻谷和玉米价格具有显著正向影响。

关键词：粮食价格粮食政策生产成本居民收入

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基于动态Svensson模型的国债利率期限结构实证分析

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统计与信息论坛 2015年第4期30卷 38-43页

作者：陈映洲张健上海财经大学经济学院上海200433 上海财经大学金融学院上海200433

国债利率期限结构的动态演化特征对利率市场化顺利推进和产品定价有积极意义。使用非平滑FamaBliss方法对交易所市场的国债交易数据进行处理,可以获取实证研究的初始数据,然后扩展静态NSS模型为动态Svensson(LSCC)模型,该模型嵌套了动态... 详细信息

国债利率期限结构的动态演化特征对利率市场化顺利推进和产品定价有积极意义。使用非平滑FamaBliss方法对交易所市场的国债交易数据进行处理,可以获取实证研究的初始数据,然后扩展静态NSS模型为动态Svensson(LSCC)模型,该模型嵌套了动态Nelson-Siegel(LSC)模型。在利用状态空间模型与Kalman滤波估计出参数后,比较LSCC模型与LSC模型对利率期限结构的拟合与预测能力。结果表明:动态Svensson(LSCC)模型具有更加显著的拟合能力和预测能力,能够更好地反映国债利率期限结构的动态特征。

关键词：国债利率期限结构动态Svensson模型 Nelson-Siegel模型

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A new geometric approach to blind source separation of bounded sources

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Progress in Natural Science:Materials International 2009年第7期19卷 891-896页

作者： j.nlong Zhang a, Guoxu zhoua, Zuyuan Yang a, Xiaoxin Liao b a School of Electrics & Information Engineering, South China University of Technology, Guangzhou 510641, China b Department of Control Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China School of Electrics & Information Engineering South China University of Technology Guangzhou 510641 China Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China

Based on the minimum-range approach, a new geometric approach is proposed to deal with blind source separation in this paper. The new approach is the batch mode of the original minimum-range approach. Compared with the original approach, the optimization algorithm of the proposed approach needs no parameters and is more efficient and reliable. In addition, the extension of minimum-rangebased approaches is discussed. The simulations show the efficiency of the proposed approach.

关键词： Blind source separation Independent component analysis Minimum-range approach

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