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j.urnal of Environmental Science and Engineering 2011年第12期5卷 1624-1641页

作者： E. Merem S. Yerramilli C. Richardson j. wesley T. Walker D. Foster j. Williams C. Romamo E Nwagboso Department of Urban and Regional Planning Jackson State University Jackson MS 39211 USA National Center for Biodefense Communications Jackson State Universi~ Jackson MS 39204 USA Department of Epidemiology and Biostatistics Jackson State University Jackson MS 39213 USA Department of Political Science Jackson State University Jackson MS 39217 USA

The proliferation of urban development with concentration in population and human-environment interaction has intensified around urban environments. This has resulted in the degradation of urban environments, overuse of natural resources and widespread pollution of ecosystems, The patterns of design initiatives continue to follow unsustainable path with impacts on stream ecosystems. Accordingly, the paper adopts geospatial information systems and sustainability principles for the identification and sequential mapping of stressors impeding natural systems in Southern Mississippi. The results not only reveal that the study area experienced some significant changes in its watershed environments, but the stream habitat ecosystem remains under stress. The recommendations for mitigating the problems range from policy considerations to the adoption of ecosystem approach.

关键词： Geospatial information systems urbanization ecological design ecosystem approach environmental degradation.

Rescue from complications after pancreaticoduodenectomies at a low-volume Caribbean center:Value of tailored peri-pancreatectomy protocols

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World j.urnal of Gastrointestinal Surgery 2024年第3期16卷 681-688页

作者： Shamir O Cawich Elij.h Dixon Parul j.Shukla Shailesh V Shrikhande Rahul R Deshpande Fawwaz Mohammed Neil W Pearce wesley Francis Shaneeta j.hnson j.hann Buj.awan Department of Surgery University of the West IndiesSt Augustine 000000Trinidad and Tobago Department of Surgery Faculty of MedicineUniversity of CalgaryCalgaryAlberta T2N2T9Canada Department of Surgery Weill Cornell Medical CollegeNew YorkNY 10065United States Department of Surgical Oncology Tata Memorial CenterHomi Bhabha National UniversityMumbai 400012India Department of Surgery Manchester Royal InfirmaryManchester M139WLUnited Kingdom University Surgical Unit Southampton General HospitalSouthampton SO166YDUnited Kingdom Department of Surgery University of the West IndiesNassau N-1184Bahamas Department of Surgery Morehouse School of MedicineAtlantaGA 30310United States Department of Surgery General Hospital in Port of SpainPort of Spain 000000Trinidad and Tobago

BACKGROUND Pancreaticoduodenectomy(PD)is a technically complex operation,with a re-latively high risk for *** ability to rescue patients from post-PD complications is as a recognized quality *** protocols were instituted at our low volume facility in the year *** To document the rate of rescue from post-PD complications with tailored protocols in place as a measure of *** A retrospective audit was performed to collect data from patients who experienced maj.r post-PD complications at a low volume pancreatic surgery unit in Trinidad and Tobago between j.nuary 1,2013 and j.ne 30,***-dardized definitions from the International Study Group of Pancreatic Surgery were used to define post-PD complications,and the modified Clavien-Dindo classification was used to classify post-PD *** Over the study period,113 patients at a mean age of 57.5 years(standard deviation[SD]±9.23;range:30-90;median:56)underwent PDs at this *** complications were recorded in 33(29.2%)patients at a mean age of 53.8 years(SD:±7.9).Twenty-nine(87.9%)patients who experienced maj.r morbidity were salvaged after aggre-ssive treatment of their ***(3.5%)died from bleeding pseudoaneurysm(1),septic shock secondary to a bile leak(1),anastomotic leak(1),and myocardial infarction(1).There was a significantly greater salvage rate in patients with American Society of Anesthesiologists scores≤2(93.3%vs 25%;P=0.0024).CONCLUSION This paper adds to the growing body of evidence that volume alone should not be used as a marker of quality for patients requiring *** low volumes at our facility,we demonstrated that 87.9%of patients were rescued from maj.r *** attributed this to several factors including development of rescue protocols,the competence of the pancreatic surgery teams and continuous,and adaptive learning by the entire institution,cul-minating in the development of tailored peri-pancreatectomy protoc

关键词： Pancreas Complication Rescue Failure Morbidity Mortality Pancreaticoduodenectomy

Statistical Analysis for Engineers and Scientists：A Computer-Based Approach 工程师和科学家实用统计分析——基于计算机的方法

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Effect of 5-FU on modulation of disarrangement of immune-associated cytokines in experimental acute pancreatitis

丛书名：国外大学优秀教材--工业工程系列

2002年

作者： j. wesley Barnes

本书是第一本从现代计算机观点出发的工程统计学教材。通过集成教材中内容宽广的软件程序，结合在工程和科研中的应用，为学生讲授概率和统计学的概念。本书包含独特、全面及用户友好的软件包（用于PC机或苹果机），其特色是以应用为取... 详细信息

ISBN: (纸本)9787900641977

本书是第一本从现代计算机观点出发的工程统计学教材。通过集成教材中内容宽广的软件程序，结合在工程和科研中的应用，为学生讲授概率和统计学的概念。本书包含独特、全面及用户友好的软件包（用于PC机或苹果机），其特色是以应用为取向，而对大多数理论问题的探讨较为直观。通过精心设计的章节式学习方式和各种练习，帮助学生在充分学习使用软件的过程中掌握各章的内容，并对所有出现的假设检验中的有效样本进行了完全和详细的统计处理。本书的主要内容包括：多元回归分析、离散随机变量的卷积和变换、双变量概率分布、假设检验的操作特性曲线、统计过程控制和非参数统计分析等。

关键词： Engineering

来源：畅想之星图书光盘版（南... 评论

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World j.urnal of Gastroenterology 2009年第16期15卷 2032-2037页

作者： Xiao-Li Chen Sang-Zhu Ciren Hui Zhang Li-Geng Duan Alexander j.wesley Department of General Surgery The Huaxi Hospital Medical Center University of Sichuan Chengdu 610041 China Department of Surgery Transplantation Division University of Cincinnati Medical Center Cincinnati OH 45267-0558 United States

AIM： To investigate the effects of 5-Fluorouracil （5-FU） on modulation of pro-inflammatory and anti-inflammatory cytokines in acute pancreatitis and the mechanism of it in the treatment of acute pancreatitis. METHODS： Male Sprague Dawley rats were assigned to 3 Groups： Group A, sham operated rats as controls （n = 7）; Group B, acute pancreatitis induced by ductal inj.ction with 5% sodium cholate at a volume of 1.0 mL/kg without any other treatment; Group C, after the pancreatitis was induced as in Group B, the rats were inj.cted intravenously with 5-FU 40 mg/kg. The animals in Groups B and C were killed at 2, 6 and 24 h after operation （n = 7）, and blood samples were taken for measurement of tumor necrosis factor-α （TNF-α）, interleukin-1 （IL-1）, interleukin-6 （IL-6）（by bioassay）, and interleukin-10 （IL-10）, transforming growth factor-β （TGF-β）（by ELISA）. The wet weight of pancreatic tissue, serum amylase levels and white blood cells were also measured. RESULTS： Four rats in Group B and one in Group C died after pancreatitis was induced. Both pro-inflammatory cytokines （TNF-α, IL-1, IL-6） at the 2 and 6 h period and the anti-inflammatory cytokines （IL-10, TGF-β） at 24 h increased significantly （P 〈 0.05） in rats of Group B. After treatment with 5-FU, TNF-α, IL-1, and IL-6 in serum of rats of Group C were inhibited at 2 and 6 h after operation （P 〈 0.05）, and IL-IO, TGF-13 were inhibited at 24 h compared to Group B （P 〈 0.05）. Obvious improvements in the severity of the acute pancreatitis, including the amylase levels, wet weight of pancreatic tissue and neutrophil counts, were also observed after treatment with 5-FU. CONCLUSION： 5-FU is an anti-metabolic and immunosuppressive agent which can minimize the abnormal immune o/tokine response and relieve the pathophysiological disorders associated with experimental acute pancreatitis.

关键词： Pancreatitis Cytokines Systemic inflammatory response syndrome 5-Fluorouracil

蚁群优化最小二乘支持向量机在测量数据拟合中的应用

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核动力工程 2018年第6期39卷 156-160页

作者：蒋波涛 Hines j.wesley 赵福宇西安工程大学电子信息学院西安710048 田纳西大学核工系诺克斯维尔田纳西37996 西安交通大学核科学与技术学院西安710049

针对传统数据拟合方法存在依赖用户经验,需预先确定估计拟合函数等缺点,提出一种基于蚁群优化最小二乘支持向量回归机(ACO-LSSVR)的数据拟合方法。该方法采用蚁群优化(ACO)对最小二乘支持向量回归机(LSSVR)的参数进行优化,获取最优参数... 详细信息

针对传统数据拟合方法存在依赖用户经验,需预先确定估计拟合函数等缺点,提出一种基于蚁群优化最小二乘支持向量回归机(ACO-LSSVR)的数据拟合方法。该方法采用蚁群优化(ACO)对最小二乘支持向量回归机(LSSVR)的参数进行优化,获取最优参数,从而建立数据拟合模型。将该方法与传统回归拟合方法用于核工程的2个测量数据拟合实例中,得到堆芯功率曲线和熔融液滴在冷却剂中运动特性曲线,将2条曲线的拟合结果进行了比较。结果表明,ACO-LSSVR具有较高的拟合精度且无需对数据分段确定拟合函数。

关键词：数据拟合核工程蚁群优化(ACO) 最小二乘支持向量回归机(LSSVR)

Measurement of the Energy Spectrum of a 6 MV Linear Accelerator Using Compton Scattering Spectroscopy and Monte Carlo-Generated Corrections

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International j.urnal of Medical Physics, Clinical Engineering and Radiation Oncology 2020年第4期9卷 186-200页

作者： Sameer Tanej. Laura j. Bartol wesley Culberson Larry A. De Werd School of Medicine and Public Health University of Wisconsin-Madison Madison USA

Purpose: The energy spectrum of a linear accelerator used for dose calculations is determined during beam commissioning by iteratively adj.sting the spectrum and comparing calculated and measured percent depth-dose curves. Direct measurement of the energy spectrum using pulse mode detectors is particularly challenging because of the high-energy, high fluence nature of these beams and limitations of the detector systems. This work implements a Compton scattering (CS) spectroscopy setup and presents detector corrections and spectral unfolding techniques to measure the spectrum of a 6 MV linear accelerator using a pulse mode detector. Methods: Spectral measurements were performed using a Varian Clinac 21EX linear accelerator and a high-purity germanium (HPGe) detector. To reduce fluence to the detector, a custom-built lead shield and a CS spectrometry setup were used. The detector was placed at CS angles of 46°, 89°, and 125°. At each of these locations, a detector response function was generated to account for photon interactions within the experimental geometry. Gold’s deconvolution algorithm was used to unfold the energy spectrum. The measured spectra were compared to simulated spectra, which were obtained using an experimentally benchmarked model of the Clinac 21EX in MCNP6. Results: Measurements were acquired and detector response corrections were calculated for all three CS angles. A comparison of spectra for all CS angles showed good agreement with one another. The spectra for all three angles were averaged and showed good agreement with the MCNP6 simulated spectrum, with all points above 400 keV falling w

关键词： Linear Accelerator Energy Spectrum Spectrometry High Purity Germanium Detectors Monte Carlo

Tolerance of Corn (<i>Zea mays</i>L.) to Early and Late Glyphosate Applications

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American j.urnal of Plant Sciences 2014年第18期5卷 2748-2754页

作者： Kris j. Mahoney Robert E. Nurse wesley j. Everman Christy L. Sprague Peter H. Sikkema Agriculture and Agri-Food Canada Harrow Canada Michigan State University East Lansing USA North Carolina State University Raleigh USA University of Guelph Ridgetown Campus Ridgetown Canada

Fifteen field experiments were conducted from 2009 to 2012 in Ontario, Canada and Michigan, USA to determine the tolerance of corn (Zea mays L.) to early (spike or 1- to 2-leaf stage) or late (8- or 10-leaf stage) applications of 900, 1800, 3600, or 7200 g·ae·ha-1 of glyphosate. Postemergence applications were evaluated for corn inj.ry, cob length and deformity, crop moisture at harvest, and yield in the absence of weed competition. In the early application experiment, no visible inj.ry was detected with applications of up to 3600 g·ae·ha-1;however, 1.4% inj.ry was observed 4 weeks after treatment (WAT) when 7200 g·ae·ha-1 was applied to 1- to 2-leaf stage corn. Yet by harvest, the observed inj.ry was transient as yields were similar to the untreated control regardless of glyphosate dose or timing. In the late application experiment, visible inj.ry tended to increase with glyphosate dose. In addition, for corn treated with 7200 g·ae·ha-1 at the 10-leaf stage, inj.ry increased over time as 6%, 11%, and 12% inj.ry was observed 1, 2, and 4 WAT, respectively. Similar to the visible inj.ry of vegetative tissue, cob deformity and reductions in yield tended to increase with glyphosate dose, but this response varied and the data were pooled into two environment groups. For example, in one environment group, corn treated with 7200 g·ae·ha-1 at the 8- and 10-leaf stage had a 9.5% and 14.6% reduction in yield, respectively. Whereas in another environment group, corn yields were similar to the untreated control regardless of glyphosate dose or timing. This research demonstrated that commercially available corn hybrids have tolerance to glyphosate at doses greater than what has been previously published or could reasonably be expected during spray overlaps in a field.

关键词： Dose Inj.ry Cob Deformity Yield

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一位谨慎的进步教育家:重新解读巴格莱

当代教育科学 2004年第13期 27-29,64页

作者： j.wesley Null 金传宝 School of Education Department of Curriculum and InstructionBaylor UniversityPOBOX97314WacoTexas76798-7314U.S. 山东师范大学教育科学学院

专业的教育家和教育历史学家对卡潘学会(Kappa DeltaPi)的创建者——威廉·钱德勒·巴格莱的忽视实在是太久了。主要源于对巴格莱主要原始著述的忽视，在很大程度上，巴格莱在许多领域所获得的声望并不都是正面的。这种有疑问的历史观... 详细信息

专业的教育家和教育历史学家对卡潘学会(Kappa DeltaPi)的创建者——威廉·钱德勒·巴格莱的忽视实在是太久了。主要源于对巴格莱主要原始著述的忽视，在很大程度上，巴格莱在许多领域所获得的声望并不都是正面的。这种有疑问的历史观点认为，巴格莱是“反进步论者”，他的著作除了在其漫长的、真实的生涯末期所发表的《要素主义者的纲领》(1938年)

关键词：巴格莱卡潘学会教育家 “要素主义”运动生平经历

高性能夹芯结构的面板与芯材的黏合性能(英文)

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j.urnal of Zhej.ang University-Science A(Applied Physics & Engineering) 2014年第1期15卷 61-67页

作者： Yi-ou SHEN wesley CANTWELL Yan LI School of Aerospace Engineering and Applied Mechanics Tongji University Department of Aerospace Engineering Khalifa University of Science Technology and Research (KUSTAR)

研究目的:通过准静态到动态的加载,研究以不锈钢点阵结构为芯材的夹芯结构的层间断裂韧性。创新要点:制备的夹芯结构不需要黏合剂,但是具有优异的面板-芯材界面性能;证明改良后的三点弯曲实验可用于研究夹芯结构在低速冲击下的界面性能... 详细信息

研究目的:通过准静态到动态的加载,研究以不锈钢点阵结构为芯材的夹芯结构的层间断裂韧性。创新要点:制备的夹芯结构不需要黏合剂,但是具有优异的面板-芯材界面性能;证明改良后的三点弯曲实验可用于研究夹芯结构在低速冲击下的界面性能。研究方法:采用改良后的三点弯曲实验(见图2)测试夹芯结构的面板-芯材断裂韧性;采用低速冲击来测试夹芯结构的抗分层性能(见图5)和吸收能量性能(见图8)。重要结论:1.采用热压法制备的以碳纤维增强环氧树脂预浸料为面板,不锈钢点阵结构为芯材的夹芯结构不需要任何粘合剂;2.所得夹芯结构在受到准静态和动态三点弯曲加载时展现了优异的抗面板-芯材界面分层性能,断裂能达到5500 j.m2;3.改良的三点弯曲实验可以用于测试低速冲击条件下夹芯结构的断裂性能。

关键词：夹芯结构层间断裂韧性弯曲性能

Locomotor analysis identifies early compensatory changes during disease progression and subgroup classification in a mouse model of amyotrophic lateral sclerosis

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Neural Regeneration Research 2017年第10期12卷 1664-1679页

作者： Melissa M.Haulcomb Rena M.Meadows Whitney M.Miller Kathryn P.Mc Millan Me Kenzie j.Hilsmeyer Xuefu Wang wesley T.Beaulieu Stephanie L.Dickinson Todd j.Brown Virginia M.Sanders Kathryn j.j.nes Department of Anatomy and Cell Biology Indiana University School of MedicineIndianapolisINUSA Research and Development Service Roudebush Veterans Administration Medical CenterIndianapolisINUSA Program in Medical Neurosciences Indiana University School of MedicineIndianapolisINUSA Department of Statistics Indiana UniversityBloomingtonINUSA Department of Epidemiology and Biostatistics Indiana UniversityBloomingtonINUSA Department of Cancer Biology and Genetics The Ohio State University Wexner Medical CenterColumbusOHUSA

Amyotrophic lateral sclerosis is a motoneuron degenerative disease that is challenging to diagnose and presents with considerable variability in *** identification and enhanced understanding of symptomatic patterns could aid in diagnosis and provide an avenue for monitoring disease *** of the m SOD1 G93 A mouse model provides control of the confounding environmental factors and genetic heterogeneity seen in amyotrophic lateral sclerosis patients,while investigating underlying disease-induced *** the present study,we performed a longitudinal behavioral assessment paradigm and identified an early hindlimb symptom,resembling the common gait abnormality foot drop,along with an accompanying forelimb compensatory mechanism in the m SOD1 G93 A *** these initial changes,m SOD1 mice displayed a temporary hindlimb compensatory mechanism resembling an exaggerated steppage *** the disease progressed,these compensatory mechanisms were not sufficient to sustain fundamental locomotor parameters and more severe deficits *** next applied these initial findings to investigate the inherent variability in B6 Sj. m SOD1 G93 A *** identified four behavioral variables that,when combined in a cluster analysis,identified two subpopulations with different disease progression rates：a fast progression group and a slow progression *** behavioral assessment paradigm,with its analytical approaches,provides a method for monitoring disease progression and detecting m SOD1 subgroups with different disease *** affords researchers an opportunity to search for genetic modifiers or other factors that likely enhance or slow disease *** factors are possible therapeutic targets with the potential to slow disease progression and provide insight into the underlying pathology and disease mechanisms.

关键词： nerve regeneration amyotrophic lateral sclerosis motoneuron degenerative disease locomotor disease progression disease variability SOD1 mouse neural regeneration