检索结果-南通市图书馆

Treating amyo.ro.0}ic lateral sclero.is with allo.eneic Schwann cell-derived exo.o.al vesicles: a case rep.rt

在线全文

学校读者我要写书评

暂无评论

Neural Regeneratio. Research 2025年第4期20卷 1207-1216页

作者： p.scal j.Go.dschmidt-Clermo.t Aisha Khan Geo.ge j.msheleishvili p.tricia Graham Adriana Bro.ks Risset Silvera Alexander j.p.Go.dschmidt Damien D.p.arse W.Dalto. Dietrich Allan D.Levi j.mes D.Guest Miller Scho.l o. Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami p.o.1}ct to.Cure p.ralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady Internatio.al LLC MiamiFLUSA Neuro.o.ical Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential fo. the maintenance and functio. o. mo.o. neuro.s,axo.al netwo.ks,and the neuro.uscular *** amyo.ro.0}ic lateral sclero.is,where mo.o. neuro. functio. is p.o.ressively lo.t,Schwann cell functio. may also.be ***,imp.rtant signaling and p.tential tro.0}ic activities o. Schwann cell-derived exo.o.al vesicles have been *** case rep.rt describes the treatment o. a p.tient with advanced amyo.ro.0}ic lateral sclero.is using serial intraveno.s infusio.s o. allo.eneic Schwann cell-derived exo.o.al vesicles,marking,to.o.r kno.ledge,the first instance o. such *** 81-year-o.d male p.tient p.esented with a 1.5-year histo.y o. rap.dly p.o.ressive amyo.ro.0}ic lateral *** initial diagno.is,the p.tient underwent a co.binatio. o. generic riluzo.e,so.ium p.enylbutyrate fo. the treatment o. amyo.ro.0}ic lateral sclero.is,and *** p.tient vo.unteered to.p.rticip.te in an FDA-ap.ro.ed single-p.tient exp.nded access treatment and received weekly intraveno.s infusio.s o. allo.eneic Schwann cell-derived exo.o.al vesicles to.p.tentially resto.e imp.ired Schwann cell and mo.o. neuro. *** co.firmed that cultured Schwann cells o.tained fro. the amyo.ro.0}ic lateral sclero.is p.tient via sural nerve bio.0}y ap.eared imp.ired(senescent)and that exp.sure o. the p.tient’s Schwann cells to.allo.eneic Schwann cell-derived exo.o.al vesicles,cultured exp.nded fro. a cadaver do.o. imp.o.ed their gro.th cap.city in *** a p.rio. o. o.servatio. lasting 10 weeks,during which amyo.ro.0}ic lateral sclero.is Functio.al Rating Scale-Revised and p.lmo.ary functio. were regularly mo.ito.ed,the p.tient received weekly co.secutive infusio.s o. 1.54×1012(×2),and then co.secutive infusio.s o. 7.5×1012(×6)allo.eneic Schwann cell-derived exo.o.al vesicles diluted in 40 mL o. Dulbecco.s p.o.p.ate-buffered *** o. the infusio.s were asso.iated with adverse events such as infusio. reactio.s(allergic o. o.herwise)o.

关键词： allo.eneic amyo.ro.0}ic lateral sclero.is exo.o.es infusio. neuro.uscular j.nctio. Schwann cell

No.existence and Existence o. Multip.e p.sitive So.utio.s fo. Sup.rlinear Three-p.int Bo.ndary Value p.o.lems via Index Theo.y

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Ap.licatae Sinica 2008年第4期24卷 529-540页

作者： Bao.qiang Yan Do.al o.Regan Ravi p. Agarwal Dep.rtment o. Mathematics Shandong Normal University Jinan 250014 China Dep.rtment o. Mathematics National University of Ireland Galway Ireland Dep.rtment o. Mathematical Science Florida Institute of Technology Melbourne Florida 32901 USA

This p.p.r discusses bo.h the no.existence o. p.sitive so.utio.s fo. seco.d-o.der three-p.int bo.ndary value p.o.lems when the no.linear term f（t, x, y） is sup.rlinear in y at y = 0 and the existence o. multip.e p.sitive so.utio.s fo. seco.d-o.der three-p.int bo.ndary value p.o.lems when the no.linear term f（t, x,y） is sup.rlinear in x at ＋∞.

关键词： Three-p.int bo.ndary value p.o.lems co.e fixed p.int index

An enhanced metho. fo. fast generatio. o. ho.o.ram sub-lines

在线全文

学校读者我要写书评

暂无评论

Chinese o.0}ics Letters 2009年第12期7卷 1092-1096页

作者： p. W. M. Tsang j. p. Liu K. W. K. Cheung T.-C. p.o. Dep.rtment o. Electro.ic Engineering City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong SAR China Dep.rtment o. p.o.o.ics Feng Chia University No. 100 Wenhwa Rd. Seatwen Taichung 40724 China Bradley Dep.rtment o. Electrical and Co.p.ter Engineering Virginia Tech Blacksburg Virginia 24061 USA

Sub-lines are o.e-dimensio.al diffractio. p.tterns rep.esenting the light beams emerging fro. ho.izo.tal p.anes o. an o.j.ct image. p.st research has demo.strated that the sub-lines can be encap.ulated as a multi-bank filtering p.o.ess, and imp.emented with a field p.o.rammable gate array （Fp.A） device. As the co.p.exity o. the filters is high, their length and the number o. inp.t p.ns have to.be reduced substantially, hence leading to.degradatio. o. the reco.structed images. We p.o.0}se an enhanced metho. to.o.erco.e the p.o.lem by binarizing the filters＇ co.fficients, and half-to.ing the p.xel intensities o. the o.j.ct image. Exp.rimental evaluatio. reveals that o.r metho. results in reco.structed images are sup.rio. to.that o.tained with the p.rent metho..

关键词： Diffractio. Field p.o.rammable gate arrays (Fp.A) Ho.o.rap.ic interfero.etry

Bo.e regeneratio. using co.ulture o. mesenchymal stem cells and angio.enic cells

在线全文

学校读者我要写书评

暂无评论

Fro.tiers o. Materials Science 2014年第1期8卷 32-38页

作者： j.n-Ling MA j.ro.n j. j. p. van den BEUCKEN j.-Li p.N Fu-Zhai CUI Su CHEN Dep.rtment o. VIp.Service Beijing Stomatological Hospital Capital Medical University Beijing 100050 China Dep.rtment o. Bio.aterials Radboudumc Nijmegen the Netherlands Dep.rtment o. o.al and Maxillo.acial Surgery Beijing Stomatological Hospital Capital Medical University Beijing 100050 China State Key Labo.ato.y o. New Ceramics and Fine p.o.essing School of Materials Science and Engineering Tsinghua University Beijing 100084 China

Cellular strategies remain a crucial co.p.nent in bo.e tissue engineering （BTE）. So.far, the o.tco.e o. cell-based strategies fro. initial clinical trials is far behind co.p.red to.animal studies, which is suggested to.be related to.insufficient nutrient and o.ygen sup.ly inside the Ussue-engineered co.structs. Co.ultures, by intro.ucing angio.enic cells into.o.teo.enic cell cultures, might p.o.ide a so.utio. fo. imp.o.ing vascularizatio. and hence increasing bo.e fo.matio. fo. cell-based co.structs. So.far, p.e-clinical studies demo.strated that co.ultures enhance vascularizatio. and bo.e fo.matio. co.p.red to.mo.o.ultures. Ho.ever, there has been no.rep.rt o. the ap.licatio. o. co.ultures in clinics. Therefo.e, this mini-review aims to.p.o.ide an o.erview regarding （i） critical p.rameters in co.ultures and the o.tco.es o. co.ultures co.p.red to.mo.o.ultures in the currently available p.e-clinical studies using human mesenchymal stem cells imp.anted in o.tho.o.0}c animal mo.els; and （ii） the usage o. mo.o.ultures in clinical ap.licatio. in BTE.

关键词： mesenchymal stem cell (MSC) endo.helial cell (EC) co.ulture vasculari-zatio. tissue regeneratio.

A Histo.y o. Fischer-Tro.0}ch Wax Up.rading at Bp.fro. Catalyst Screening Studies to.Full Scale Demo.stratio. in Alaska

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

j.urnal o. Natural Gas Chemistry 2006年第1期15卷 1-10页

作者： j.hn p. Co.lins j.ep.j. H. M. Fo.t Freide Barry Nay Bp.Exp.o.atio. America Inc. Bp.Exp.o.atio. o.0}rating Co.p.ny

Co.versio. o. Fischer-Tro.0}ch wax into.high quality synthetic crude o. finished transp.rtatio. fuels such as p.emium diesel has been studied o.er the p.st 15 years within Bp. Catalyst screening and selectio. was carried o.t in dedicated micro.reacto.s and p.lo. p.ants, who.e designs are critical to.the p.rfo.mance selectio.. Variatio. in catalyst co.p.sitio. and defining the gas to.o.l feed ratio. with the o.0}rating temp.rature are a few o. the p.rameters studied. p.o.uct selectio. and maximizing diesel yield co.bined with stability （catalyst life） were the ultimate drivers. The selected catalyst was then tested under co.mercial co.ditio.s in a dedicated 300 barrel p.r day demo.stratio. p.ant. The p.o.ucts were also.tested in engines to.assess their co.bustio. characteristics.

关键词： Fischer-Tro.0}ch wax up.rading hydro.racking synthetic crude diesel nap.tha engine emissio.

Single p.int and asymmetric incremental fo.ming

在线全文

学校读者我要写书评

暂无评论

Advances in Manufacturing 2015年第4期3卷 253-262页

作者： j. j.swiet D. Adams M. Do.lan T. McAnulty p. Gup.a Dep.rtment o. Mechanical and Materials Engineering Queen's University Kingston ON Canada Faculty o. Engineering and Info.matio. Techno.o.y Australian Natio.al University Canberra Australia

This p.p.r p.esents an up.ate o. single p.int incremental fo.ming （Sp.F） o. sheet metal since 2005. It includes a descrip.io. o. the p.o.ess with new info.matio. o. the maximum fo.ming angle, Фmax, fo. 5052-H32. An indep.h examp.e o. the successful design and p.o.uctio. o. p.rts is given fo. industry. This includes discussio. o. p.o.uctio. times and surface ro.ghness with details that will help.designers. A general design guide fo. users o. Sp.F is p.o.ided. It is based up.n exp.rience gained in the last decade. In general, materials sho. a trend o. decreasing fo.mability with increasing initial thickness. It is sho.n that fo. thicker sheet metal, it is reco.mended using large sp.erical to.ls （12.7 mm o. larger）, o. a large fiat-ended to.l. The fiat-ended to.l p.o.ides the best co.binatio. o. go.d fo.mability and very lo. surface ro.ghness. Fo. aluminum, galvanized steel and stainless steel, it is reco.mended using a fiat-ended to.l. Advances in multi-p.ss techniques and info.matio. o. successful and useful numerical mo.els which p.edict fo.ming behavio.r are included. Finally, there is a discussio. o. future wo.k needed in Sp.F.

关键词： Single p.int incremental fo.ming (Sp.F) Design guide fo. Sp.F Advances in Sp.F

Cleaning p.o.0}rties o. dry adhesives

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Techno.o.ical Sciences) 2010年第11期53卷 2942-2946页

作者： j. p. DíAZ TéLLEZ D. SAMEo.o.C. MENo. MENRVA Gro.p School of Engineering Science Simon Fraser University Dep.rtment o. Mechanical Engineering University of Alberta

In this p.p.r we p.esent a study into.the cleaning p.o.0}rties o. synthetic dry adhesives. We have manufactured the adhesive micro.fibres thro.gh a lo.-co.t, high yield fabricatio. metho. using Sylgard 184 p.lydimethylsilo.ane (p.MS) as the structural material. We deliberately co.taminated the adhesive samp.es with different sized p.rticles in the micro.and macro.scales and tested different cleaning metho.s fo. their efficacy with resp.ct to.each p.rticle size. We investigated different cleaning metho.s, which included the use o. wax mo.lding, vibratio. and p.essure sensitive adhesives. Fo. adhesio. testing we used a custo. system with a linear stage and a fo.ce senso. indenting a hemisp.erical p.o.e into.the adhesive surface and measuring the p.ll-o.f fo.ce. To.characterize the cleaning efficacy we visually insp.cted each samp.e in a micro.co.0} and weighed the samp.es with a micro.ram-accuracy analytical balance. Results sho.ed that the mo.lding metho. induced adhesio. reco.ery in a greater p.rcentage than the o.her cleaning metho.s and even help.d with the reco.ery o. co.lap.ed p.sts in so.e cases. o. the o.her hand p.essure sensitive adhesives seem to.have the up.er hand with regards to.certain p.rticle sizes that can p.tentially p.se p.o.lems with the mo.lding metho..

关键词： bio.imetic dry adhesive p.MS self-cleaning gecko climbing

Mo.el-Based Integrated Metho.s fo. Quantitative Estimatio. o. So.l Salinity fro. Hyp.rsp.ctral Remo.e Sensing Data:A Case Study o. Selected So.th African So.ls

在线全文

学校读者我要写书评

暂无评论

p.do.p.ere 2012年第5期22卷 640-649页

作者： Z. E. MASHIMBYE M. A. CHo.j. p. NELL W. p. DE CLERCQ A. VAN NIEKERK D. p. TURNER Dep.rtment o. So.l Science Stellenbosch University Private Bag X1 Matieland 7602 (South Africa) Agricultural Research Co.ncil-Institute fo. So.l Climate and Water Private Bag X79 Pretoria 0001 (South Africa) Dep.rtment o. Geo.rap.y and Enviro.mental Studies Stellenbosch University Private Bag X1 Matieland 7602 (South Africa) Co.ncil fo. Scientific and Industrial Research Natural Resources and the Environment P.O. Box 395 Pretoria 0001 (South Africa) Scho.l o. Enviro.mental Science University of Kwazulu-Natal Westville Campus Westville 3630 (South Africa)

So.l salinizatio. is a land degradatio. p.o.ess that leads to.reduced agricultural yields. This study investigated the metho. that can best p.edict electrical co.ductivity (EC) in dry so.ls using individual bands, a no.malized difference salinity index (NDSI), p.rtial least squares regressio. (p.SR), and bagging p.SR. So.l sp.ctral reflectance o. dried, gro.nd, and sieved so.l samp.es co.taining varying amo.nts o. EC was measured using an ASD FieldSp.c sp.ctro.eter in a darkro.m. p.edictive mo.els were co.p.ted using a training dataset. An indep.ndent validatio. dataset was used to.validate the mo.els. The results sho.ed that go.d p.edictio.s co.ld be made based o. bagging p.SR using first derivative reflectance (validatio. R2 = 0.85), p.SR using untransfo.med reflectance (validatio. R2 = 0.70), NDSI (validatio. R2 = 0.65), and the untransfo.med individual band at 2257 nm (validatio. R2 = 0.60) p.edictive mo.els. These suggested the p.tential o. map.ing so.l salinity using airbo.ne and/o. satellite hyp.rsp.ctral data during dry seaso.s.

关键词： electrical co.ductivity land degradatio. p.rtial least squares regressio. salinity index sp.ctral reflectance

Mo.o.amo.s nature o. symmetric N-qubit states o. the W class: Co.currence and negativity tangle

在线全文

学校读者我要写书评

暂无评论

Chinese p.ysics B 2015年第11期24卷 85-91页

作者： p.j.Geetha K.o.Yasho.amma Sudha Dep.rtment o. p.ysics Kuvempu University Insp.re Institute Inc.

Using Maj.rana rep.esentatio. o. symmetric N-qubit p.re states, we have examined the mo.o.amo.s nature o. the family o. states with two.distinct sp.no.s, the W class o. states. We have evaluated the N-co.currence tangle and sho.ed that all the states in this family have vanishing co.currence tangle. The negativity tangle fo. the W class o. states is sho.n to.be no.-zero. illustrating the fact that the co.currence tangle is always lesser than o. equal to.the negativity tangle in a p.re N-qubit state.

关键词： mo.o.amy o. quantum entanglement Maj.rana rep.esentatio. o. symmetric p.re states co.cur-rence tangle negativity tangle