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Buechel Pappas Resurf.cing Shoulder Replacement: Evolution and over 40 Years of.Clinical Experience

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Open j.urnal of.Orthopedics 2024年第5期14卷 218-228页

作者： f.ederick f. Buechel Michael j. Pappas Rutgers Nj.Medical School Newark NJ USA South Mountain Orthopaedic Associates South Orange NJ USA New j.rsey Institute of.Technology Newark NJ USA

Background: Early exploration of.the semi constrained “f.oating-Socket” total shoulder replacement (TSR) in 1974 led to a prolif.ration of.various unconstrained designs that allowed resection or retention of.the humeral head, depending upon the pathological process involved. Degenerative glenohumeral arthritis with mild to moderate involvement of.subchondral bone allowed f.r a resurf.cing option, while severe humeral head involvement required a partial or f.ll humeral head replacement attached to an intramedullary stem f.r f.xation. All components evolved f.om cemented to cementless application by 1982. The purpose of.this paper is to describe the progression of.Buechel-Pappas (B-P) shoulder replacement development f.om the early 1970’s in both cemented and cement less applications. Methods: Clinical evaluations of.“f.oating-Socket” TSR, f.llowed by B-P stem-type, resurf.cing types, bipolar-type and revision components, all of.which comprise the B-P Shoulder Replacement System, were perf.rmed over a 49-year period. Results: “f.oating-Socket” implants improved the results of.simple, constrained ball-in-socket designs, but generally f.iled by glenoid component loosening in both chimpanzee and human applications. Unconstrained resurf.cing-type components, both anatomical humeral head and f.ll proximal humeral components, were quite successf.l, with minimal f.ilures observed in long-term studies. Bipolar salvage implants, used f.r severe proximal def.ciencies, revisions and massive rotator cuf. arthropathy, were also very successf.l;providing overhead range of.motion in many patients. Conclusions: Resurf.cing hemiarthroplasty, in patients with intact or repairable rotator cuf. mechanisms, gave the most satisf.ctory results and were the least technically complicated to perf.rm, requiring minimal instrumentation. Resurf.cing of.f.ll proximal humeral def.ciencies, using f.moral resurf.cing components, gave similar clinical results to more complex semi-constrained devices,

关键词： Total Shoulder Replacement Resurf.cing Shoulder Replacement

Seroprevalence and Molecular Biodiverisity of.Hepatitis C Inf.ction in Congolese Diabetics

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Open j.urnal of.Gastroenterology 2019年第1期9卷 22-27页

作者： A. Mongo-Onkouo M. G. Ibobi Gassaye Deby E. Bouenizabila C. P. Ahoui Apendi N. Andzouana Mbamognoua j. f. mimiesse monamou A. Boumba N. A. Itoua-Ngaporo B. I. Atipoibara H. G. Monabeka j.-R. Ibara Department of.Gastroenterology and Internal Medicine Brazzaville University Hospital Center Brazzaville Congo f.culty of.Health Sciences Ngouabi Marien University Brazzaville Congo Department of.Metabolic Diseases of.Brazzaville University Hospital Center Brazzaville Congo Laboratory Service Hospital General of.Louandj.li Pointe- Noire Congo

Summary: There is no evidence f.r comorbidity diabetes and hepatitis C virus inf.ction in the Congo. The aim of.this work was to determine the seroprevalence and molecular biodiversity of.HCV in order to contribute to improving the management of.Congolese diabetics. Patients and methods: It was a cross-sectional study that took place f.om 1 f.bruary to 30 September 2018 at the Brazzaville University Hospital, the Diabcare Health Center and the Adolphe Cissé Hospital in Pointe-Noire. It concerned diabetic patients f.llowed in Brazzaville and Pointe-Noire agreeing to the study, af.er obtaining the opinion of.the ethics committee of.the research in health science. All samples collected were screened f.r the presence of.anti HCV Ab using a rapid ALERE HCV test and the Monolisa HCV Ag-Ab ultra test f.r conf.rmation in Congo. Detection of.the viral RNA was done by PCR retrotranscription and genotyping was perf.rmed according to the reverse hybridization technique in f.ance. Data analysis was done with EpiInf. 6.0 sof.ware (2016);the proportions were compared using the Chi-square test or the f.sher test at the signif.cance level of.5%. Results: Of.447 patients with diabetes mellitus, 49 had HCV positive serology and the sex ratio was 0.63. Seroprevalence of.AC anti HCV was 11% (49/447);HCV RNA was detectable in 71.4% (n = 35) patients. The average age of.the population was 62 ± 10 years with extremes ranging f.om 26 to 82 years. The circulating genotypes were 4 (97.1%) and 1 (2.8%). Subtyping was def.ned in 17.64% (n = 6) of.genotype 4 patients;undef.ned in 82.36% (n = 28) of.Genotype 4 patients, and in one of.genotype 1 patients. The subtypes identif.ed were subtype 4e (60%), subtype 4e (8.8%), subtype 4a/4c/4d (5.8%), and subtype 4h (2.9%). Conclusion: The prevalence of.HCV is high in our study. These are important data f.r the improvement of.the management of.diabetics.

关键词： Hepatitis C Diabete Congo

Seroprevalence and Molecular Biodiversity of.Hepatitis B and Delta Virus Inf.ctions in the Republic of.Congo

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Open j.urnal of.Gastroenterology 2018年第12期8卷 448-454页

作者： A. Mongo-Onkouo R. Itoko Okombi A. Boumba f. R. Niama C. P. Ahoui-Apendi j. f. mimiesse monamou N. A. Itoua-Ngaporo L. C. Atipo-Ibara Ollandzobo Ikobo Deby Gassaye M. Ngalessami Mouakosso C. S. Adoua B. I. Atipo-Ibara j.-R. Ibara Gastro-Enterology and Internal Medicine CHU of Brazzaville Brazzaville Congo f.culty of.Health Sciences Ngouabi Marien University Brazzaville Congo Laboratory Service Hospital General of.Louandj.li Pointe-Noire Congo National Public Health Laboratory Brazzaville Congo Inf.nt Pediatric Service CHU of Brazzaville Brazzaville Congo

Hepatitis B virus (HBV) inf.ction is a maj.r public health problem in the world. In Congo, studies on the prevalence of.HBV inf.ction are common but HDV inf.ction is rare. Obj.ctive: Contribute to improve the management and prevention of.HBV and HDV inf.ctions. Patients and Methods: This was a descriptive and cross-sectional study conducted f.om j.nuary to August 2016 in the health services of.the various departments of.Congo and at the national public health laboratory in Brazzaville. All patients with HBsAg surf.ce antigen who were at least 18 years old and who consented to the study were included. The HBs antigen was f.rst tested by a rapid test then conf.rmed by ELISA. All HBsAg positive patients were subsequently subj.cted to a second ELISA test f.r Delta antibody. The techniques of.extraction and conventional and specif.c gene amplif.cation were carried out on plasma f.r the identif.cation of.the genotypes of.the two viruses. The data analysis was done with EpiInf. V7 sof.ware. The proportions were compared using the Chi-square test or the f.sher test at the signif.cance level of.5%. Results: 1618 subj.cts were included, of.whom 180 were positive f.r HBsAg, a f.equency of.11.12%. The sex ratio (M/f. was 0.77%, the mean age was 40.2 ± 15.6 years with extremes ranging f.om 18 to 88 years. Of.the 180 HBsAg positive, 22 were anti-VHD positive, a f.equency of.12.22%. HBV DNA was amplif.ed in 83.8% (151/180), HDV RNA in 63.6% (14/22). f.r HBV, three genotypes were identif.ed: E (46.9%), A (43.7%) and D (9.4%), however f.r VHD three genotypes D1, D5, D8 were identif.ed. Conclusion: Co-inf.ction of.hepatitis B and Delta viruses is common in Congo. The management and prevention of.hepatitis B must take into account the reality of.this co-inf.ction.

关键词： Seroprevalence Molecular Biodiversity Hepatitis B Virus and Delta Congo

miniSCIDOM: a scintillator-based tomograph f.r volumetric dose reconstruction of.single laser-driven proton bunches

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High Power Laser Science and Engineering 2024年第2期12卷 41-50页

作者： A.Corvino M.Reimold E.Beyreuther f.-E.Brack f.Kroll j.Pawelke j.D.Schilz M.Schneider U.Schramm M.E.P.Umlandt K.Zeil T.Ziegler j.Metzkes-Ng Helmholtz-Zentrum Dresden–Rossendorf DresdenGermany Technische Universität Dresden DresdenGermany OncoRay–National Center f.r Radiation Research in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Current af.iliation:Institut Curie UniversitéPSLCNRS UMR3347OrsayFrance Current af.iliation:Universitätsklinikum f.eiburg FreiburgGermany

Laser plasma accelerators(LPAs)enable the generation of.intense and short proton bunches on a micrometre scale,thus of.ering new experimental capabilities to research f.elds such as ultra-high dose rate radiobiology or material *** spectrally broadband,laser-accelerated proton bunches allow f.r tailored volumetric dose deposition in a sample via single bunches to excite or probe specif.c sample *** rising number of.such experiments indicates a need f.r diagnostics providing spatially resolved characterization of.dose distributions with volumes of.approximately 1 cm^(3) f.r single proton bunches to allow f.r f.st online *** we present the scintillator-based miniSCIDOM detector f.r online single-bunch tomographic reconstruction of.dose distributions in volumes of.up to approximately 1 cm^(3).The detector achieves a spatial resolution below 500μm and a sensitivity of.100 *** detector perf.rmance is tested at a proton therapy cyclotron and an LPA proton *** experiments’primary f.cus is the characterization of.the scintillator’s ionization quenching behaviour.

关键词： beam monitoring detectors laser-driven proton beams scintillator-based diagnostics ultra-high dose rate

Thermo-kinetic characteristics on stabilizing hetero-phase interf.ce of.metal matrix composites by crystal plasticity f.nite element method

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j.urnal of.Materials Science & Technology 2024年第2期169卷 53-67页

作者： Y.B.Zhang S.j.Song f.Liu State Key Laboratory of.Solidif.cation Processing Northwestern Polytechnical UniversityXi’an 710072China Analytical&Testing Center Northwestern Polytechnical UniversityXi’an 710072China

Using dislocation-based constitutive modeling in three-dimension crystal plasticity f.nite element(3D CPf.)simulations,co-def.rmation and instability of.hetero-phase interf.ce in dif.erent material systems were herein studied f.r polycrystalline metal matrix composites(MMCs).Local stress and strain f.elds in two types of.3layer MMCs such as f.c/f.c Cu-Ag and f.c/bcc Cu-Nb have been predicted under simple compressive ***,more severe strain-induced interf.ce instability can be observed in the f.c/bcc systems than in the f.c/f.c systems upon ref.ning to metallic nanolayered composites(MNCs).By detailed analysis of.stress and strain localization,it has been demonstrated that the interf.ce instability is always accompanied by high-stress concentration,i.e.,thermodynamic characteristics,or high strain prevention i.e.,kinetic characteristics,at the hetero-phase *** then f.llows that the thermodynamic driving f.rceG and the kinetic energy barrier Q during dislocation and shear banding can be adopted to classif. the def.rmation modes,f.llowing the so-called thermo-kinetic *** by inserting a high density of.high-energy interf.ces into the Cu-Nb composites,such thermo-kinetic integration at the hetero-phase interf.ce allows a successf.l establishment of.MMCs with the high△G-high Q def.rmation mode,which ensures high hardening and unif.rm strain distri-bution,thus ef.iciently suppressing the shear band,stabilizing the hetero-phase interf.ce,and obtaining an exceptional combination in strength and *** hetero-phase interf.ce chosen by a couple of.thermodynamics and kinetics can be def.ned as breaking the thermo-kinetic correlation and has been proposed f.r artif.cially designing MNCs.

关键词： Thermodynamics and kinetics Physics-based constitutive modeling Hetero-phase interf.ce Crystal plasticity f.nite element

Synthesis of.Silver Nanoparticles f.om Honeybees and Its Antibacterial Potential

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Open j.urnal of.Medical Microbiology 2024年第1期14卷 77-92页

作者： Akamu j. Ewunkem Niore’s j.hnson A’lyiha f. Beard Ilunga Tshimanga Brittany j.stice j.f.ery Meixner Department of.Biological Sciences Winston Salem State University Winston Salem NC USA Department of.Clinical Science and Laboratory Science Winston Salem State University Winston Salem NC USA

Honeybees (Apis mellif.ra) are important pollinators of.f.owering plants and agricultural crops contributing annually to billions of.dollars in revenues to crop production. Honeybees have an average lif.span between 8 weeks to 5 years. Dead honeybees are abundantly available in beehives and can be utilized as an alternative source to synthesize nanoparticles. In recent years, biologically synthesized nanoparticles have been pref.rred over their chemical counterparts. However, honeybee-based-green synthesis of.nanoparticles has not been explored yet. Herein, we report the biosynthesis of.silver nanoparticles f.om honeybees and its antibacterial activity. The synthesis of.silver nanoparticles was monitored visually through a gradual change in color. f.rthermore, the biosynthesized nanoparticles were conf.rmed and characterized by UV-visible spectroscopy. Scanning Electron Microscope was utilized to analyze the average size and morphologies of.the biosynthesized nanoparticles. Subsequently, the antibacterial potential of.the biosynthesized silver nanoparticles was tested against selected Gram-positive and Gram-negative bacterial strains. It was f.und that a distinct color change f.om yellow to brown in the reaction solution suggested the f.rmation of.silver nanoparticles. The biosynthesized nanoparticles exhibited absorption maxima at 430 nm. The SEM analysis conf.rmed the spherical and cuboidal shape of.the biosynthesized silver nanoparticles with a size range between 10 - 40 nm. f.rthermore, the biosynthesized silver nanoparticles exhibited strong antimicrobial potential against tested Gram-positive and Gram-negative bacteria strains by aggregating on the cell surf.ce. This study showcases the biomedical and agricultural applications of.biosynthesized silver nanoparticles f.om honeybee wings. .

关键词： Honeybee Bacteria Green Synthesis Nanoparticles Antimicrobial

Collisionless shock acceleration of.protons in a plasma slab produced in a gas j.t by the collision of.two laser-driven hydrodynamic shockwaves

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Matter and Radiation at Extremes 2024年第2期9卷 12-25页

作者： j.-R.Marquès L.Lancia P.Loiseau P.f.restier-Colleoni M.Tarisien E.Atukpor V.Bagnoud C.Brabetz f.Consoli j.Domange f.Hannachi P.Nicolaï M.Salvadori B.Zielbauer LULI CNRSÉcole PolytechniqueCEASorbonne UniversitéInstitut Polytechnique de Paris91128 Palaiseau CedexFrance CEA DAMDIF91297 Arpajon CedexFrance UniversitéParis-Saclay CEALMCE91680 Bruyères-le-ChatelFrance CENBG CNRS-IN2P3Universitéde Bordeaux33175 Gradignan CedexFrance GSI Helmholtzzentrum f.r Schwerionenf.rschung GmbH Planckstraße 164291 DarmstadtGermany University of.Darmstadt Schloßgartenstr.764289 DarmstadtGermany ENEA f.sion and Technologies f.r Nuclear Saf.ty Department C.R.FrascatiVia Enrico Fermi 45FrascatiRomeItaly CELIA Universitéde Bordeaux–CNRS–CEA33405 TalenceFrance UniversitéParis-Saclay CEALIDYL91191 Gif-sur-YvetteFrance

We have recently proposed a new technique of.plasma tailoring by laser-driven hydrodynamic shockwaves generated on both sides of.a gas j.t[Marquès et al.,*** 28,023103(2021)].In a continuation of.this numerical work,we study experimentally the inf.uence of.the tailoring on proton acceleration driven by a high-intensity picosecond laser in three cases:without tailoring,by tailoring only the entrance side of.the picosecond laser,and by tailoring both sides of.the gas *** tailoring,the acceleration is transverse to the laser axis,with a low-energy exponential spectrum,produced by Coulomb *** the f.ont side of.the gas j.t is tailored,a f.rward acceleration appears,which is signif.cantly enhanced when both the f.ont and back sides of.the plasma are *** f.rward acceleration produces higher-energy protons,with a peaked spectrum,and is in good agreement with the mechanism of.collisionless shock acceleration(CSA).The spatiotemporal evolution of.the plasma prof.le is characterized by optical shadowgraphy of.a probe *** ref.action and absorption of.this beam are simulated by post-processing 3D hydrodynamic simulations of.the plasma *** with the experimental results allows estimation of.the thickness and near-critical density of.the plasma slab produced by tailoring both sides of.the gas *** parameters are in good agreement with those required f.r CSA.

关键词： acceleration hydrodynamic collision

覆盖UVA1的新型防晒剂MCE对色素和老化体征的影响:一项在两个不同遗传背景的人群进行的为期8周、随机、自身对照、前瞻性户外研究

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中华皮肤科杂志 2024年第6期57卷 579-580页

作者： f. f.ament D. G. Mercurio B. Muller j. Li C. Tricaud f. Bernerd A. Roudot D. Candau T. Passeron L'Oréal Research and Innovation Clichy France L'Oréal Research and Innovation Rio de Janeiro Brazil L'Oréal Research and Innovation Shanghai China L'Oréal Research and Innovation Aulnay-sous-Bois France L'Oréal Research and Innovation Chevilly-Larue France CHU Nice Department of Dermatology Université Côte d'Azur Nice France Université Côte d'Azur INSERM U1065 C3M Nice France

一、引言在不同的紫外线(UV)波段中,长波UVA(UVA1,340~400nm)具有更高的皮肤穿透力,并且受气象条件和臭氧层厚度等环境参数的影响较小,因此更容易到达皮肤深部的真皮层,对细胞成分(如DNA、脂质和蛋白质)造成氧化损伤。UVA1已经越来越多... 详细信息

一、引言在不同的紫外线(UV)波段中,长波UVA(UVA1,340~400nm)具有更高的皮肤穿透力,并且受气象条件和臭氧层厚度等环境参数的影响较小,因此更容易到达皮肤深部的真皮层,对细胞成分(如DNA、脂质和蛋白质)造成氧化损伤。UVA1已经越来越多地被发现与衰老、致癌作用、多种皮肤疾病和色素问题相关。

关键词： UVA1 真皮层自身对照致癌作用皮肤疾病防晒剂遗传背景氧化损伤

Thermoluminescence characterization of.natural and synthetic irradiated Ce-monazites

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j.urnal of.Rare Earths 2024年第4期42卷 643-650页

作者： V.Correcher C.Boronat j.Garcia-Guinea j.f.Benavente T.Rivera-Montalvo CIEMAT Av.Complutense 4028040MadridSpain MNCN-CSIC J.Gutierrez Abascal 228006MadridSpain Instituto Politécnico Nacional CICATA-IPNAv.Legaria 694Mexico City11500Mexico

The thermoluminescence(TL)emission of.synthetic and natural Ce-monazites was characterized here to determine the potential application in the identif.cation of.microscopic def.cts f.om a qualitative point of.view trying to link each TL peak to a chemical-physical *** kinetic parameters that lead the luminescence processes were calculated by means of.variable heating rate and computing glow curve deconvolution methods and allow identif.ing three groups of.components at~90,130 and 290℃(f.r the mineral sample)and~90,170,220,270 and 320℃(f.r the synthetic CePO_(4):Nd_(0.20),La_(0.25)).The main dif.erences appreciated in these complex TL curves are mainly due to(i)the content of.impurities(natural sample contains lanthanides as well as U 0.60%and Th 5.22%)and(ii)the degree of.crystallinity of.the samples which is directly related to the type of.impurities(synthetic monazite relies only on Nd and La).The behavior of.the dose response in the range of.1-8 Gy is similar f.r both samples;the TL intensity increases linearly as the dose increases without changes in the position of.the maxima,denoting f.rst-order kinetic luminescence *** peak could be mostly associated with structural def.cts(i.e.,phase transitions),chemical reactions(i.e.,Ce3+?Ce4+redox reaction,dehydration or dehydroxylation processes)or intrinsic def.cts(i.e.,f.enkel def.cts,ODCs or NBOHCs).

关键词： Thermoluminescence Kineticparameters Phosphate Ce-monazite Def.cts Rare earths