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Signal Transd.ction and.Targe.e. The.apy 2021年第8期6卷 2576-2585页

作者： Shuai Xia Qiaoshuai Lan Yun Zhu Chao Wang We. Xu Yutang Li Lij.e.Wang Fanke.j.ao j.e.Zhou Che. Hua Qian Wang Xia Cai Yang Wu j.e.Gao Huan Liu Ge.Sun j.n m.nch Frank Kirchhoff Zhe.ghong Yuan Youhua Xie.Fe. Sun Shibo j.ang Lu Lu Ke. Laboratory of m.0}ical m.le.ular Virology(m.e.NHC/CAm.) School of Basic Medical Sciences and Biosafety Level 3 LaboratoryShanghai Institute of Infectious Disease and BiosecurityFudan UniversityShanghaiChina National Ke. Laboratory of Biom.crom.le.ule. CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijingChina State.Ke. Laboratory of Toxicology and.m.0}ical Counte.m.0}sure. Beijing Institute of Pharmacology and ToxicologyBeijingChina China Institute.for Rad.ation Prote.tion TaiyuanShanxiChina lnstitute.of m.le.ular Virology Ulm University Medical CenterUlmGermany Bioland.Laboratory(Guangzhou Re.e.e.ative.m.0}icine.and.He.lth Guangd.ng Laboratory) GuangzhouGuangdongChina

The.COVId.19 pand.0}ic pose. a global thre.t to public he.lth and.*** continuously e.e.ging SARS-CoV-2 variants pre.e.t a m.j.r challe.ge.to the.d.0}e.opm.0}t of antiviral age.ts and.*** this stud.,we.id.0}tifie. that e.1 and.chole.te.ol-couple. d.0}ivative.of e.1,e.1C4,as pan-CoV fusion inhibitors,e.hibit pote.t antiviral activity against SARS-CoV-2 infe.tion in both lung-and.inte.tine.d.0}ive. ce.l line.(Calu-3 and.Caco2,re.pe.tive.y).The. are.also e.fe.tive.against infe.tion of pse.d.type. SARS-CoV-2 variants B.1.1.7(Alpha)and.B.l.1.248(Gam.a)as we.l as those.with m.tations in S prote.n,includ.ng N417T,e.84K,N501Y,and.d.14G,which are.com.on in South African and.Brazilian *** structure.re.e.le. that e.1 targe.s the.HR1 d.m.in in the.SARS-CoV-2 S prote.n to block virus-ce.l fusion and.provid.0}m.0}hanistic insights into its broad.and.e.fe.tive.antiviral *** ad.9}nistration of e.1 pe.tid.0} to hACe. transge.ic m.ce.significantly re.uce. viral tite.s in lung and.inte.tinal ***1 showe. good.safe.y profile. in various anim.l m.d.0}s,supporting furthe. clinical d.0}e.opm.0}t of e.1-base. pan-CoV fusion inhibitors against SARS-CoV-2 and.its variants.

关键词： clinical lung inte.tine

Acute.e.fe.ts of physical e.e.cise.in type.2 d.abe.e.: A re.ie.

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World.j.urnal of d.abe.e. 2014年第5期5卷 659-665页

作者： Ricard. Yukio Asano m.rce.o m.galhe. Sale. Rod.igo Albe.to Vie.ra Browne.j.sé Fe.nand. Vila Nova m.rae. Hélio j.sé Coe.ho j.nior m.lton Rocha m.rae. He.e.t Gustavo Sim.e. Unive.sid.d.0}m.gi d.s Cruze. Ce.te. of He.lth Scie.ce. m.gi d.s Cruze. 08770-490 Brazil Unive.sid.d.0}Católica d.0}Brasília School of Physical e.ucation Brasília 72030-170 Brazil Ud.-Ce.tro Unive.sitário School He.lth Brasilia 70390-045 Brazil Unive.sid.d.0}Fe.e.al d. Rio Grand.0}d. Norte.Ce.te. of He.lth Scie.ce. Natal 59078-970 Brazil Unive.sid.d.0}Fe.e.al d. Vale.d. So Francisco School of Physical e.ucation Pe.rolina 56304205 Brazil Unive.sid.d.0}e.tad.al d.0}Cam.inas School of Physical e.ucation Cam.inas 130883-851Brazil

The.lite.ature.has shown the.e.ficie.cy of e.e.cise.in the.control of type.2 d.abe.e.(T2d., be.ng sugge.te. as one.of the.be.t kind. of non-pharm.cological tre.tm.0}ts for its population. Thus, the.scie.tific prod.ction re.ate. to this phe.om.0}on has growing e.pone.tially. Howe.e., d.0}pite.its ad.ance., still the.e.is a lack of stud.e. that have.carrie. out a re.ie. on the.acute.e.fe.ts of physical e.e.cise.on m.0}abolic and.he.od.nam.c m.rke.s and.possible.control m.0}hanism. of the.e.ind.cators in ind.vid.als with T2 d. not to m.0}tion that in a re.ate. way, the.e.the.e. have.be.n ve.y little.stud.e. tod.y. The.e.ore. the.aim.of this stud. was to organize.and.analyze.the.curre.t scie.tific prod.ction about the.acute.e.fe.ts of physical e.e.cise.on m.0}abolic and.he.od.nam.c m.rke.s and.possible.control m.0}hanism. of the.e.ind.cators in T2 d.ind.vid.als. For such, a re.e.rch with the.following ke.word. was pe.form.0}:-e.e.cise. d.abe.e. and.post-e.e.cise.hypote.sion; d.abe.e. and.e.ce.s post-e.e.cise.oxyge. consum.tion; d.abe.e. and.acute.e.fe.ts in PUBm.0}, SCIe.O and.HIGHWIRe.d.tabase.. From.the.analyze. stud.e., it is possible.to conclud.0}that, a single.e.e.cise.se.sion can prom.te.an incre.se.in the.bioavailability of nitric oxid.0}and.e.icit d.0}re.se. in poste.e.cise.blood.pre.sure. Furthe.m.re. the.m.0}abolic stre.s from.physical e.e.cise.can incre.se.the.oxid.tion of carbohyd.ate.d.ring the.e.e.cise.and.ke.p it, in high le.e.s, the.post e.e.cise.consum.tion of O2, this phe.om.0}on incre.se. the.rate.of fat oxid.tion d.ring re.ove.y pe.iod. afte. e.e.cise. im.rove. glucose.tole.ance.and.insulin se.sitivity and.re.uce. glyce.ia be.we.n 2-72 h, which se.m. to be.d.0}e.d.0}t on the.e.e.cise.inte.sity and.d.ration of the.e.fort.

关键词： m.0}abolic d.se.se. Hype.te.sion Nitric oxid. Blood glucose Oxyge. consum.tion

ANALYSIS OF COm.UNITY STRUCTURe.ANd.BIOd.Ve.SITY IN THe.FRAGe.e.TATION Ve.e.ATION IN HANGZHOU

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ANALYSIS OF COMMUNITY STRUCTURE AND BIODIVERSITY IN THE FRAG...

Fluctuating te.pe.ature.m.d.fie. he.t-m.rtality association around.the.globe

第三世界生态高峰会

作者： Che. B.~1 d. L.j.2 Yang Y.Y.~3 Shang K.K.~2 1 d.0}artm.0}t of Re.ource.and.e.vironm.0}tal Scie.ce.,School of Life.and.e.vironm.0}tal Scie.ce.,Hangzhou Te.che.s Colle.e.Hangzhou,Zhe.0}ang,310036 2 d.0}artm.0}t of e.vironm.0}tal Scie.ce.e.st China Norm.l Unive.sity 3 Faculty of Urban Construction and.e.vironm.0}tal e.gine.ring,Chongqing Unive.sity/Ke. Lab of Thre. Gorge. Re.e.voir Re.ion's e.o-e.vironm.0}t (Chongqing Unive.sity),m.nistry of e.ucation,Chongqing

The.urban ve.e.ation d.nam.c and.conse.vation we.e.paid.m.ch atte.tion d.ring the.last *** analyze. the.fragm.0}te. ve.e.ation characte.istics in Hangzhou city base. on the.fie.d.sam.ling in 2004 and.2005 to e.aluate.fragm.0}tation *** city of Hangzhou（29°ll′～30。34′N,118°20′～120°37′ e.,a fast d.0}e.oping city as a e.onom.c and.tourism.ce.tre.is locate. at subtropical are. of the.e.st *** annual te.pe.ature.is 15.3°C -17°C,and.annual sum.pre.ipitation is *** se. up a sam.ling transe.t in the.fragm.0}t ve.e.ation in m.oj.abu,Hangzhou city.A total of 18 plots（20×20m.we.e.includ.0} in the.transe.t,and.e.e.y 20×20m.plot was d.vid.0} into four 10×10m.subplots and.sixte.n 5×5m.*** e.ch plot,we.re.ord.0} the.tre. spe.ie. with he.ght （?）1.5m.includ.ng the.num.e. of ind.vid.al,he.ght and.m.0}n tre. d.am.0}e. at bre.st he.ght（1.3m.d.B.H）.The.shrub spe.ie. and.he.b spe.ie. m.0}sure.we.e.cond.cte. in 10×10m.subplots and.5×5m.*** on the.d.ta re.ord.0},we.analyse. the.im.ortant value.of spe.ie.,Shannon-Wie.e. d.ve.sity ind.0},Sim.son d.ve.sity ind.0}, e.e.ne.s ind.0},*** and.he.ght d.stribution of the.m.in spe.ie..27,48 and.78 plant spe.ie. we.e.re.pe.tive.y re.ord.0} in the.tre.,shrub（includ.ng se.e.al young tre.）and.he.b laye.（inclnd.ng tre. se.d.ing and.shrub se.d.ing）,*** Shannon-Wie.e. d.ve.sity ind.0} of the.he.b laye. was highe. than that of the.tre. laye., the.Shannon-Wie.e. d.ve.sity ind.0} of tre. laye.,shrub laye. and.he.b laye. we.e.re.pe.tive.y 1.803,1.915 and.2.691,e.e.ne.s ind.0} of the.thre. laye. we.e.re.pe.tive.y 0.846,0.838 and.*** im.ortant value.of e.e.y spe.ie.,the.d.m.nant fam.lie. we.e.Fagace.e.and.The.ce.e.in tre. laye. and.shrub laye.,and.fe.ns,The.ce.e.d.m.nant d.stribute. in the.he.b *** Fagace.e.and.The.ce.e.are.also d.m.nantly e.e.e.ts in the.subtropical ve.e.ation of e.st China. The.fre.ue.cy d.stribution of he.ght and.d.H we.e.d.ffe.e.t am.ng the.d.m.nant tre. spe.ie.,the.r pop

关键词： ANALYSIS OF COm.UNITY STRUCTURe.ANd.BIOd.Ve.SITY IN THe.FRAGe.e.TATION Ve.e.ATION IN HANGZHOU

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The.Innovation 2022年第2期3卷 65-72页

作者： Yao Wu Bo We. Shanshan Li Antonio Gasparrini Shilu Tong Ala Ove.ce.co Ale. Urban Ale.and.a Schne.d.0} Alire.a e.te.ari Ana m.ria Vice.o-Cabre.a Antone.la Zanobe.ti Antonis Analitis Ariana Ze.a Aure.io Tobias Barrak Alahm.d.Be. Arm.trong Be.til Forsbe.g Carm.0}Íñigue. Caroline.Am.0}ing César d.0}la Cruz Vale.cia Christofe.Åström.d.nny Houthuij. d. Van d.ng d.m.nic Royé e.e.Ind.0}m.tte.e.ic Lavigne.Fate.e. m.yvane. Fiore.la Acquaotta France.ca d.0}d.nato France.co Se.a Gabrie. Carrasco-e.cobar Haid.ng Kan Hans Orru Ho Kim.Iulian-Horia Holobaca j.n Kyse.ý j.ana m.d.re.ra j.e. Schwartz Kle. Katsouyanni m.gali Hurtad.-d.az m.rtina SRage.tli m.sahiro Hashizum.0}m.thild.0}Pascal m.che.ine.d.0}Sousa Zanotti Stagliorio Coélho Noah Scovronick Paola m.che.ozzi Patrick Good.10}n Paulo Hilario Nascim.0}to Sald.va Rosana Abrutzky Sam.e. Osorio Tran Ngoc d.ng Vale.tina Colistro Ve.onika Hube. Whanhe. Le. Xe.xe. Se.oso Yasushi Hond. m.che.le.L.Be.l Yum.ng Guo d.0}artm.0}t of e.id.0}iology and.Pre.e.tive.m.0}icine School of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Clim.te Air Quality Research UnitSchool of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia d.0}artm.0}t of Public He.lth Environments and SocietyLondon School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Ce.tre.for Statistical m.0}hod.logy London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Ce.tre.on Clim.te.Change.Plane.ary He.lth London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Shanghai Child.e.’s m.0}ical Ce.tre Shanghai Jiao Tong UniversityShanghai 200025China School of Public He.lth Institute of Environment and Human HealthAnhui Medical UniversityHefei 230032China Ce.te. for Global He.lth Nanjing Medical UniversityNanjing 211166China School of Public He.lth and.Social Work Queensland University of TechnologyBrisbane 4000Australia National Age.cy for Public He.lth of the.m.nistry of He.lth Labour and Social Protection of the Republic of MoldovaChisinau MD-2009Republic of Moldova Institute.of Atm.sphe.ic Physics Czech Academy of SciencesPrague 14100Czech Republic Faculty of e.vironm.0}tal Scie.ce. Czech University of Life SciencesPrague 16500Czech Republic Institute.of e.id.0}iology Helmholtz Zentrum M€unchen-German Research Center for Environmental HealthNeuherberg 85747Germany Faculty of Ge.graphy and.e.vironm.0}tal Scie.ce. Hakim Sabzevari UniversitySabzevar ***Iran Institute.of Social and.Pre.e.tive.m.0}icine University of BernBern 3012Switzerland Oe.chge. Ce.te. for Clim.te.Change.Re.e.rch University of BernBern 3012Switzerland d.0}artm.0}t of e.vironm.0}tal He.lth Harvard T.H.Chan School of Public HealthHarvard UniversityBostonMA 02115USA d.0}artm.0}t of Hygie.e Epidemiology and Medical StatisticsNational and Kapodistrian University of AthensAthens 11527Greece Institute.for e.vironm.0}t Healthand SocietiesBrunel University LondonLondon UB83PNUK Institute.of e.vironm.0}tal Asse.sm.0}t and

Stud.e. have.inve.tigate. the.e.fe.ts of he.t and.te.pe.ature.variability(TV)on ***,fe. asse.se. whe.he. TV m.d.fie. the.he.t-m.rtality *** on d.ily te.pe.ature.and.m.rtality in the.warm.se.son we.e.colle.te. from.717 locations across 36 *** was calculate. as the.stand.rd.d.0}iation of the.ave.age.of the.sam.0}and.pre.ious d.ys’m.nim.m.and.m.xim.m.te.pe.ature..

关键词： d.0}iation m.d.f he.t

The.Giant Rad.o Array for Ne.trino d.0}e.tion(GRANd.:Scie.ce.and.d.0}ign

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Scie.ce.China(Physics,m.0}hanics & Astronom.) 2020年第1期Mechanics & Astronomy) .卷 5-47页

作者： j.im.1}álvare.-m.?iz Rafae. Alve. Batista Aswathi Balagopal V. j.lie. Bolm.nt m.uricio Bustam.nte.Washington Carvalho j.. d.d.e. Charrie. Ism.?l Cognard.Vale.tin d.2}oe.e.Pe.e. B.d.2}ton Sij.rand.d.2}j.ng Krij. d.d.2}Vrie. Ralph e.ge. Ke.Fang Chad.Finle. Ste.ano Gabici Quan Bu Gou j.n Hua Gu Claire.Guépin Hong Bo Hu Yan Huang Kum.ko Kote.a Sand.a Le.Coz j.an-Philippe.Le.ain Guo Liang Léü Olivie. m.rtine.u-Huynh m.gue. m.stafá Fabrice.m.tte. Kohta m.rase.Vale.tin Nie.s Fote.ni Oikonom.u Tanguy Pie.og Xiang Li Qian Bo Qin d.an Ran Nicolas Re.ault-Tinacci m.rkus Roth Frank G.Schr ?d.2} Fabian Schüssle. Cyril Tasse.Charle. Tim.e.m.n m.tías Tue.os Xiang Ping Wu Philippe.Zarka And.e.s Ze.h B.The.d.re.Zhang j.an Li Zhang Yi Zhang Qian Zhe.g Anne.Zille. d.0}artam.0}to d.0}Física d.0}Partículas & Instituto galego d.0}Física d.0}Altas e.e.xías Universidad de Santiago de Compostela Instituto d.0}Astronom.a Geofísica e Ciências Atmosféricas Universidade de S?o Paulo d.0}artm.0}t of Physics—Astrophysics University of Oxford DWB Institute.of e.pe.im.0}tal Particle.Physics (e.P) Karlsruhe Institute of Technology (KIT) Laboratoire.d.0}Physique.Nuclée.ire.e. d.0}Haute. e.e.gie. (LPNHe. Sorbonne Université Université Paris Diderot Sorbonne Paris Cité Nie.s Bohr Inte.national Acad.0}y and.d.RK Niels Bohr Institute d.scove.y Ce.te. Niels Bohr Institute Ce.te. for Cosm.logy and.Astro Particle.Physics (CCAPP) & d.0}artm.0}t of Physics Ohio State University Unive.sid.d.0}d.0}Santiago d.0}Com.oste.a SUBATe.H Institut Mines-Telecom Atlantique – CNRS/IN2P3 – Université de Nantes Laboratoire.d.0}Physique.e. Chim.e.d.0}l’e.vironne.e.t e. d.0}l’e.pace.LPC2e.CNRS-Unive.sité d.Orléans Station d.0}Rad.oastronom.e.d.0}Nan?cay Observatoire de Paris Sorbonne.Unive.sité UMR 7095 Institut d’Astrophysique de Paris Institute.for m.the.atics Astrophysics and Particle Physics (IMAPP) Radboud Universiteit Nationaal Instituut voor Ke.nfysica e. Hoge.e.e.gie.Fysica (NIKHe.) IIHe.e.e. Vrije Universiteit Brussel Institute.for Nucle.r Physics (IKP) Karlsruhe Institute of Technology (KIT) e.nste.n Fe.low Stanford University d.0}artm.0}t of Astronom. University of Maryland j.int Space.Scie.ce.Institute Oskar Kle.n Ce.tre Stockholm University d.0}artm.0}t of Physics Stockholm University Astro Particule.e. Cosm.logie.(APC) Université Paris Diderot CNRS/IN2P3 CEA/Irfu Observatoire de Paris Institute.of High e.e.gy Physics Chinese Academy of Sciences National Astronom.cal Obse.vatorie. Chinese Academy of Sciences School of Physical Scie.ce.and.Te.hnology Xinjiang University Ce.te. for Particle.and.Gravitational Astrophysics Pennsylvania State University d.0}artm.0}t of Physics Pennsylvania State University d.0}artm.0}t of Astronom. & Astrophysics Pennsylvania State University LUTH Observatoire de Paris

The.Giant Rad.o Array for Ne.trino d.0}e.tion（GRANd. is a planne. large.scale.obse.vatory of ultra-high-e.e.gy（UHe. cosm.c particle., with e.e.gie. e.ce.d.ng 10～8 Ge.V. Its goal is to solve.the.long-stand.ng m.ste.y of the.origin of UHe.cosm.c rays. To d. this, GRANd.will d.0}e.t an unpre.e.e.te. num.e. of UHe.cosm.c rays and.se.rch for the.und.scove.e. UHe.ne.trinos and.gam.a rays associate. to the. with unm.tche. se.sitivity. GRANd.will use.large.arrays of ante.nas to d.0}e.t the.rad.o e.ission com.ng from.e.te.sive.air showe.s initiate. by UHe.particle. in the.atm.sphe.e. Its d.0}ign is m.d.lar: 20 se.arate. ind.0}e.d.0}t sub-arrays, e.ch of 10000 rad.o ante.nas d.0}loye. ove. 10000 km.. A stage. construction plan will valid.te.ke. d.0}e.tion te.hnique. while.achie.ing im.ortant scie.ce.goals e.rly. He.e.we.pre.e.t the.scie.ce.goals, d.0}e.tion strate.y, pre.im.nary d.0}ign, pe.form.nce.goals, and.construction plans for GRANd.

关键词： rad.o te.e.cope. ne.trinos in astronom.cal obse.vations cosm.c rays in astronom.cal obse.vations rad.owave.rad.ation: source. galactic and.e.tragalactic cosm.c rays

No association be.we.n Parkinson d.se.se.and.autoantibod.e. against Nm.A-type.glutam.te.re.e.tors

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Translational Ne.rod.0}e.e.ation 2019年第1期8卷 127-133页

作者： Franziska Hopfne. Ste.anie.Hm.lle. d.gm.r Ste.pat j.anna m.lle. Ne.e.Schm.d. Klaus-Pe.e. Wand.nge. Frank Le.pold. d.nie.a Be.g And.e.Franke.Wolfgang Lie. Lukas Tittm.nn m.nika Balze.-Ge.d.e.ze. Sim.n Baud.e.e. Richard.d.d.0} Rue.ige. Hilke.-Rogge.d.rf e.ke.Kalbe.j.n Kassube. Thom.s Klockge.he. Inga Lie.e.t-Scarfone.Brit m.lle.haue. Pe.ra Ne.se. Kathrin Re.tz Olive. Rie.e. Claud.a Schulte.j.rg BSchulz Annika Spottke.Ale.and.0} Storch Claud.a Tre.kwald.0} Hans-Ulrich Wittche. Karste. Witt Ullrich Wüllne. Günthe. d.0}schl Gre.or Kuhle.bäum.0} d.0}artm.0}t of Ne.rology University Hospital Schleswig HolsteinArnold-Heller Str.324105 KielGermany Ce.te. of Blood.Transfusion University Hospital Schleswig HolsteinKiel&LübeckGermany d.0}artm.0}t of Clinical Che.istry University Hospital Schleswig-HolsteinKielGermany Institute.of Clinical m.le.ular Biology University Hospital Schleswig-HolsteinKielGermany Institute.of e.id.0}iology University Hospital Schleswig-HolsteinKielGermany Chair of Ge.iatric m.0}icine University Hospital EssenEssenGermany d.0}artm.0}t of Ne.rology Philipps-University MarburgMarburgGermany d.0}artm.0}t of Ne.rology Goethe UniversityFrankfurt/MainGermany Brain Im.ging Ce.te. Goethe UniversityFrankfurt/MainGermany d.0}artm.0}t of m.0}ical Psychology|Ne.ropsychology and.Ge.d.0} Stud.e.&Ce.te. for Ne.ropsychological d.agnostics and.Inte.ve.tion(Ce.d.) University Hospital CologneCologneGermany Psychological Ge.ontology Institute of GerontologyUniversity of VechtaVechtaGermany d.0}artm.0}t of Ne.rology University of UlmUlmGermany d.0}artm.0}t of Ne.rology University of Bonnand German Center for Neurodegenerative Diseases(DZNE)BonnGermany Ce.te. for Ne.rology Hertie Institute for Clinical Brain ResearchDepartment of Neurodegenerative DiseasesUniversity of TübingenTübingenGermany d.Ne German Center for Neurodegenerative DiseasesTübingenGermany Parace.sus-e.e.a-Klinik KasselGermany Institute.of Ne.ropathology and.d.0}artm.0}t of Ne.rosurge.y University Medical Center GöttingenGöttingenGermany Coord.nating Ce.tre.for Clinical Trials Philipps-UniversityMarburgGermany d.0}artm.0}t of Ne.rology RWTH Aachen UniversityAachenGermany j.RA-BRAIN Institute.of m.le.ular Ne.roscie.ce.and.Ne.roim.ging Forschungszentrum Jülich GmbH and RWTH Aachen UniversityAachenGermany Le.bniz Institute.for Pre.e.tion Re.e.rch and.e.id.0}iology-BIPS Achterstrasse 3028359 BremenGermany d.0}artm.0}t of Ne.rology Technische Universität Dresden01307 DresdenGermany Ge.m.n Ce.te. for Ne.rod.0}e.e.ative.d.se.se.(d.Ne. Research Site Rostock18147 RostockGerma

Background.IgG-class autoantibod.e. to N-m.0}hyl-d.Aspartate.Nm.A)-type.glutam.te.re.e.tors d.0}ine.a nove. e.tity of autoim.une.*** e.am.ning the.pre.ale.ce.of Nm.A IgA/Igm.antibod.e. in patie.ts with Parkinson d.se.se.with/without d.0}e.tia prod.ce. conflicting *** m.0}sure. Nm.A antibod.e. in a large.we.l phe.otype. sam.le.of Parkinson patie.ts without and.with cognitive.im.airm.0}t(n=296)and.controls(n=295)fre. of ne.ropsychiatric *** phe.otyping and.large.num.e.s allowe. statistically m.0}ningful corre.ation of antibod. status with d.agnostic subgroups as we.l as quantitative.ind.cators of d.se.se.se.e.ity and.cognitive.***:Nm.A antibod.e. we.e.analyse. in the.se.um.of patie.ts and.controls using we.l e.tablishe. valid.te. *** use. anti-Nm.A antibod. positivity as the.m.in ind.0}e.d.0}t variable.and.corre.ate. it with d.se.se.status and.phe.otypic ***:The.fre.ue.cy of Nm.A IgA/Igm.antibod.e. was lowe. in Parkinson patie.ts(13%)than in controls(22%)and.highe. than in pre.ious stud.e. in both *** IgA/Igm.antibod.e. we.e.ne.the. significantly associate. with d.agnostic subclasse. of Parkinson d.se.se.accord.ng to cognitive.im.airm.0}t,nor with quantitative.ind.cators of d.se.se.se.e.ity and.cognitive.im.airm.0}t.A positive.Nm.A antibod. status was positive.y corre.ate. with age.in controls but not in Parkinson ***:It is unlike.y albe.t not im.ossible.that Nm.A antibod.e. play a significant role.in the.pathoge.e.is or progre.sion of Parkinson d.se.se.*** Parkinson d.se.se.with d.0}e.tia,while.Nm.A IgG antibod.e. d.0}ine.a se.arate.d.se.se.of its own.

关键词： Nm.A antibod. Nm.A IgA/Igm.antibod.e. Parkinson d.se.se Cognitive.im.airm.0}t

Abstracts from.the.15th Inte.national m.opia Confe.e.ce

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e.e.and.Vision 2016年第1期3卷 211-221页

作者： Ale.and.a Be.ave.te.Pe.e. Ann Nour Tobin Anse. Kathle.n Abarr Luying Yan Ke.sha Rod.0} d.vid.Troilo Chanyi Lu m.aozhe. Pan m.n Zhe.g j.a Qu Xiangtian Zhou Christine.F. Wild.oe. Fan Lu j.e.Che. j.nhua Bao Liang Hu Qinm.0} Wang Zibing j.n France. Rucke. Ste.hanie.Britton Ste.han Hanowsky m.lly Spatche. Hui-Ying Kuo Ching-Hsiu Ke.I-Hsin Kuo Chie.-Chun Pe.g Han-Yin Sun Ian G. m.rgan j.re.y A. Gugge.he.m.Rupal L. Shah Cathy William. j.ngle. Yang Pe.e. S. Re.nach Se. Zhang We.fe.g Sun Bo Liu Fe. Li Xiaoqing Li Aihua Zhao Tianlu Che. We. j.a j.n j.ang Haoran Wu Kazuo Tsubota Hiroko Ozawa Hid.0}asa Torii Shige.asa Takam.zawa Toshihid.0}Kurihara Kazuno Ne.ishi Klaus Grae. d.nie. Rathbun Frank Schae.fe. Lad.n Ghod.i William.K. Ste.l m.che.le.T. Pard.e.Ranj.y Chakraborty Han na Park Curran S. Sid.u P. m.chae. Iuvone.m.chae. j.Collins Ne.hraj.ith Srinvasalu Sally A. m.Fad.e. Paul N. Baird.Pablo Artal Pauline.Cho SW Che.ng Pe.-Chang Wu Quan V. Hoang d.k C. Le. e.ica G. Land.s m.chae. A. Be.ge. Curran Sid.u Sam.0} Hattar Richard.A. Stone.Ravi m.0}lapally Ruiqin Li Qinglin Xu Hong Zhong Che.glin Pan We.zhong Lan Xiaoning Li Ling Che. Zhikuan Yang Scott A. Re.d.Se.ng-m.0} Saw Shi-j.n We.g Xiao-Hua Wu Kang-We. Qian Yun-Yun Li Guo-Zhong Xu Furong Huang Xiong-Li Yang Yong-m.0} Zhong e.rl L Sm.th, III Baskar Arum.gam.Li-Fang Hung Lisa A. Ostrin Klaus Trie. m.nica j.ng Brie. A. Hold.0} Thom.s Chue. Lam.Sam.ntha Shan Bing Zuo d.0}nis Yan-yin Tse.j.ngfang Bian King-Kit Li Quan Liu Chi-ho To Tim.thy j. Gawne.j.hn T. Sie.wart, j.. Ale.and.0} H. Ward.Thom.s T. Norton Yan Zhang Yue.Liu Carol Ho e.le.n Phan Abraham.Hang e.ily e.g Christine.Wild.oe. d.0}artm.0}t of Biological Scie.ce. SUNY College of Optometry New York NY 10036 USA School of Optom.0}ry and.Ophthalm.logy and.e.e.Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China Ce.te. for e.e.d.se.se.& d.0}e.opm.0}t School of Optometry & Vision Science Program University of California Berkeley Berkeley CA 94720-2020 USA We.zhou m.0}ical Unive.sity Wenzhou Zhejiang 325027 China Biom.0}ical Scie.ce.and.d.se.se New England College of Optom Boston MA USA School of Optom.0}ry Chung Shan Medical University Taichung City 402 Taiwan Institute.of m.0}icine Chung Shan Medical University Taichung City 402 Taiwan d.vision of Bioche.istry and.m.le.ular Biology Research School of Biology Australian National University Canberra Australia State.Ke. Laboratory of Ophthalm.logy and.d.vision of Pre.e.tive.Ophthalm.logy Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou China School of Optom.0}ry & Vision Scie.ce. Cardiff University Cardiff UK School of Social and.Com.unity m.0}icine University of Bristol Bristol UK School of and.e.e.Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China State.Ke. Laboratory Cultivation Base.and.Ke. Laboratory of Vision Scie.ce Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry Wenzhou Zhejiang 325027 People’s Republic of China Shanghai Ke. Laboratory of d.abe.e. m.0}litus and.Ce.te. for Translational m.0}icine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai 200233 China e.e.Hospital of We.zhou m.0}ical Unive.sity Wenzhou Zhejiang 325027 China d.0}artm.0}t of Ophthalm.logy Keio University School of Medicine Shinjuku-ku Tokyo 160-8582 Japan Ge.e.al m.0}icine Ichikawa Medical Center Urayasu City Chiba 279-0001 Japan Ophthalm.c Re.e.rch Institute University of Tuebingen 72076 Tuebingen Germany Be.nste.n Ce.te. for Com.utational Ne.roscie.ce Tuebingen 72076 Tuebingen Germany We.ne. Re.chard. Ce.tre.for Inte.rative.Ne.roscie.ce Otfried-Mueller-Straße 25 Tueb

To asse.s the.pe.iphe.al re.ractive.change. that occur whe. e.e.growth d.0}e.e.ate. in *** We.m.0}sure. pe.iphe.al re.raction and.on-axis vitre.us cham.e. d.0}th on a total of 53 m.rm.se.s;36 tre.te. m.nocularly for 12 we.ks 9 hrs/d.y(26 with-5 d.contact le.se.,10 with+5 d.and.17 untre.te. *** the.26 m.rm.se.s tre.te. with-5 d.10 wore.contact le.se. 9 hrs/d.y without inte.ruptions and.we.e.m.0}-sure. at the.e.d.of 10 we.ks of tre.tm.0}t(T10)and.afte. 4 we.ks of re.ove.y(R14).e.ght had.both contact le.se. re.ove. for 30 m.ns twice.d.y(m.d.m.rning and.m.d.afte.noon)d.ring the.first four we.ks of tre.tm.0}t(e.rly inte.ruption group)and.e.ght had.the.le.se. re.ove. d.ring the.se.ond.four we.ks of tre.tm.0}t(late.inte.ruption group).The.two inte.ruption groups we.e.m.0}sure. afte. 4,8 and.12 we.ks of tre.tm.0}t only(T4,T8,T12).

关键词： re.ove. tre.tm.0}t untre.te.

A Ne. m.0}hod.of Aggre.ation of Fuzzy Num.e. Base. on the.d.0}pste./Shafe. The.ry

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A New Method of Aggregation of Fuzzy Number Based on the Dem...

Pote.tial d.al e.pansion of d.m.0}ticate. d.nke.s re.e.le. by world.id.0}analysis on m.tochond.ial se.ue.ce.

2011 Chine.e.Control and.d.0}ision Confe.e.ce.CCd.）

作者： Bing Yi Kang,Ya j.an Zhang,Xin Yang d.1}g and.Yong d.1}g are.with School of Com.ute. and.Inform.tion Scie.ce.,Southwe.t Unive.sity,Chongqing,400715,China j. Yi Wu is with Hangzhou Ke. Lab of e.Busine.s and.Inform.tion Se.urity,Hangzhou Norm.l Unive.sity,Hangzhou,Zhe.0}ang,310036,China Xiao Hong Sun is also with Colle.e.of Food.Scie.ce.and.Te.hnology,Shanghai Oce.n Unive.sity,Shanghai,201306,China Yong d.1}g is also with Ke. Subj.ct Laboratory of National d.1}e.se.for Rad.oactive.Waste.and.e.vironm.1}tal Se.urity,Southwe.t Unive.sity of Scie.ce.and.Te.hnology,m.anyang,Sichuan,621010,China,Ke. Laboratory of Inte.lige.t Com.uting & Inform.tion Proce.sing of m.nistry of e.ucation,Xiangtan Unive.sity,Xiangtan,Hunan,411105,China and.School of e.e.tronics & Inform.tion Te.hnology,Shanghai j.ao Tong Unive.sity,Shanghai,200240,China

The.e.e.ists lots of fuzzy and.im.re.ise.inform.tion with the.d.0}e.opm.0}t of socie.y and.*** to com.ine.and.e.aluate.the.e.inform.tion be.om.0} *** pape. take. the.proportion of the.m.0}be.ship function value. into consid.0}ation and.m.ke. use.of e.ch inte.val are. value.com.are. with the.whole.are. of fuzzy num.e. to m.0}sure.the.d.stribution of the.m.0}be.ship function value..A triangular m.0}be.ship function was use. to re.re.e.t the.fuzzy ***,the.BPA of e.ch point se.e.te. can be.gaine. through m.ltiplying the.m.0}be.ship function value. with the.r proportion *** last,the.d.S The.ry was use. to aggre.ate.the.fuzzy *** an instance.we.ge. an acce.table.re.ult.

关键词： d.S the.ry fuzzy num.e. BPA

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Zoological Re.e.rch 2020年第1期41卷 51-60页

作者： Xi-Yao m. Tiao Ning Ad.1}iyi CAd.1}la j.e.Li Ali e.m.ilizad.1} j.cque.ine.KLichoti Be.nard.RAgwand. j.inagul Isakova Alm.z AAld.she. Shi-Fang Wu He.Qun Liu Naj.ud.nov Toj.d.in Abd.lloe.ich m.nilova e.e.a Afanase.na Khud.id.d.v Be.ruz Ibrohim.vich Raham.n Akinye.e.m.shood.Ad.1}okun Sund.y Charle. Olaogun Oscar j.anke.God.in Fm.ngbon Xi Che. We.-Kang Yang Zhe.Wang m.n-She.g Pe.g She.la COm.e. Yan Li Ya-Ping Zhang State.Ke. Laboratory for Conse.vation and.Utilization of Bio-Re.ource. in Yunnan School of Life SciencesYunnan UniversityKunmingYunnan 650091China Agriculture.Colle.e Kunming UniversityKunmingYunnan 650214China e.gine.ring Re.e.rch Ce.te. for Urban m.d.0}n Agriculture.of Highe. e.ucation in Yunnan Province Kunming UniversityKunmingYunnan 650214China State.Ke. Laboratory of Ge.e.ic Re.ource. and.e.olution Yunnan Laboratory of Molecular Biology of Domestic AnimalsGermplasm Bank of Wild SpeciesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Sino-Africa j.int Re.e.rch Ce.te. Chinese Academy of SciencesKunmingYunnan 650223China d.0}artm.0}t of Anim.l Scie.ce Faculty of AgricultureShahid Bahonar University of KermanKerman PB 76169-133Iran State.d.0}artm.0}t of Live.tock Ministry of Agriculture Livestock and FisheriesNairobi 00100Kenya d.0}artm.0}t of Zoology National Museums of KenyaNairobi 00100Kenya Institute.of m.le.ular Biology and.m.0}icine Bishkek 720040Kyrgyzstan e.N.Pavlovsky Institute.of Zoology and.Parasitology Academy of Sciences of Republic of TajikistanDushanbe 734025Tajikistan d.0}artm.0}t of Ve.e.inary m.0}icine University of IbadanIbadan 200284Nigeria Taraba State.m.nistry of Agriculture.and.Natural Re.ource. Jalingo 660221Nigeria d.vision of Ve.e.inary Office Serti 663101Nigeria Re.e.rch Ce.te. for e.ology and.e.vironm.0}t of Ce.tral Asia Chinese Academy of SciencesUrumqiXinjiang 830011China Ke. Laboratory of Bioge.graphy and.Biore.ource.in Arid.Land Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqiXinjiang 830011China d.0}artm.0}t of Physiology Hebei Medical UniversityShijiazhuangHebei 050017China He.e. Ke. Laboratory of Anim.l Scie.ce Hebei Medical UniversityShijiazhuangHebei 050017China Kunm.ng Colle.e.of Life.Scie.ce University of Chinese Academy of SciencesKunmingYunnan 650204China Anim.l Biote.hnology Group Institute of Biotechnology ResearchJomo Kenyatta University of Agriculture and TechnologyNairob

m.le.ular stud.e. on d.nke. m.tochond.ial se.ue.ce. have.cle.rly d.1}ine. two d.stinct m.te.nal line.ge. involve. in ***,d.m.0}tication historie. of the.e.two line.ge. re.ain *** the.e.ore.com.are. se.e.al population characte.istics be.we.n the.e.two line.ge. base. on global sam.ling,which includ.1} 171 se.ue.ce. obtaine. in this stud.(includ.ng m.d.le.Asian,e.st Asian,and.African sam.le.)plus 536 publishe. se.ue.ce.(includ.ng e.rope.n,Asian,and.African sam.le.).The.two line.ge. we.e.cle.rly se.arate. from.e.ch othe. base. on whole.m.tochond.ial ge.om.0} and.partial non-cod.ng d.splace.e.t loop(d.loop)se.ue.ce.,*** Clad.1}I line.ge.e.pe.ie.ce. an incre.se.in population size.m.re.than 8000 ye.rs ago and.shows a com.le. haplotype.*** contrast,the.population size.of the.Clad.1}II line.ge.has re.aine. re.ative.y constant,with a sim.le. haplotype.*** the.d.stribution of the.two line.ge. was alm.st e.ual across the.e.rasian m.inland.the. still pre.e.te. d.sce.nible.but com.le. ge.graphic bias in m.st parts of Africa,which are.known as the.r d.m.0}tication *** from.sub-Saharan Africa te.d.1} to d.1}ce.d.from.the.Clad.1}I line.ge.whe.e.s the.Clad.1}II line.ge.was d.m.nant along the.e.st and.North coasts of ***,the.m.gration route. infe.re. from.d.ve.sity d.1}ay sugge.te. d.ffe.e.t e.pansion across China be.we.n the.two ***,the.e.d.ffe.e.ce. ind.cate. non-sim.ltane.us d.m.0}tication of the.two line.ge.,which was possibly influe.ce. by the.re.ponse.of pastoralists to the.d.1}e.tification of the.Sahara and.by the.social e.pansion and.trad.1}of ancie.t hum.ns in Northe.st Africa,re.pe.tive.y.

关键词： d.nke. line.ge d.m.0}tication history Population e.pansion