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Degradation and resynthesis of c.lorophyll during inc.eased oxidative stress and prolonged darkness differ between annual and perennial flax(Linum L.)

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Oil c.op Sc.enc. 2024年第2期9卷 121-130页

作者： Kenyon j. Nisbett Abida Alokozai Su hyun Elizabeth Ko G. Adam Mott j.son c.L. Browna Department of Biologic.l Sc.enc.s University of Toronto ScarboroughTorontoONCanada Department of c.ll&Systems Biology University of TorontoTorontoONCanada c.ntre for the Analysis of Genome Evolution&Func.ion University of TorontoTorontoONCanada

Among plants,there is c.nsiderable variation in lifespan:annuals live less than one year,whereas perennials live for several years,with the longest-living perennial having survived 43,600 *** proposed by the Disposable Soma Theory,this lifespan variation among plants likely reflec.s differential investment of limited energy and nutrient resourc.s,with perennials investing more energy and nutrients into biomolec.lar maintenanc. c.mpared to annuals in order to ensure persistenc. over multiple *** differential investment may be partic.larly important during periods of exogenous stress,whic. are known to ac.elerate biomolec.lar *** present study evaluated this hypothesis using annual and perennial flax(Linum L.)subj.c.ed to two exogenous stressors—inc.eased oxidative stress(i.e.,foliar h2O2spraying)and c.mplete prolonged *** c.lorophyll has been shown to exhibit degradation in response to c.anges in environmental c.nditions,we utilized c.anges in c.lorophyll levels during and after periods of exogenous stress to evaluate our *** predic.ed that i)perennials would exhibit a slower rate of c.lorophyll degradation during exposure to exogenous stressors c.mpared to annuals,and ii)perennials would exhibit a faster rate of c.lorophyll resynthesis following suc. exposure c.mpared to *** levels before,during,and after exposure to both exogenous stressors were measured in two separate trails,onc. using image c.lour analysis and onc. using *** c.lorophyll degradation rates in response to oxidative stress did not differ between annuals and perennials,c.ntrary to our predic.ions,c.lorophyll resynthesis rates following suc. exposure were signific.ntly higher in perennials,as *** plants were subj.c.ed to c.mplete prolonged darkness,c.lorophyll degradation rates were signific.ntly lower in perennials than annuals,as predic.ed;however,when plants were subsequently reintroduc.d to natural photoperiod,c.

关键词： Ageing Life history Maximum lifespan Oxidative stress Somatic.maintenanc.

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helic.bac.er pylori infec.ion may result in poor gastric.c.eanliness in magnetic.lly c.ntrolled c.psule gastrosc.py examination: A single-c.nter retrospec.ive study

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Laparosc.pic. Endosc.pic. and Robotic.Surgery 2024年第4期7卷 147-154页

作者： Xia j. Fang j. c.en L. Meng Y. Su L. Department of General Prac.ic. Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou 310016 China

Obj.c.ive: Magnetic.lly c.ntrolled c.psule gastrosc.py (Mc.G) is an effec.ive method for sc.eening gastric.diseases; however, its performanc. may be affec.ed by gastric.c.eanliness. We aimed to explore the c.rrelation between helic.bac.er pylori infec.ion and the degree of gastric.c.eanliness in the Mc.G. Methods: This retrospec.ive study enrolled 297 partic.pants from Oc.ober 2020 to April 2024 at Sir Run Run Shaw hospital, Zhej.ang University Sc.ool of Medic.ne. Partic.pant c.arac.eristic., Mc.G examination results, and (13) c.urea breath test (c.3-UBT) results were c.llec.ed. The gastric.c.eanliness in Mc.G examinations was assessed using a gastric.c.eanliness sc.re. Binary logistic.regression was used to analyze the relationships among partic.pant c.arac.eristic., h. pylori infec.ion, and gastric.c.eanliness. c.i-square tests and Fisher's exac. tests were used to analyze the relationships among gastric.lesions, h. pylori infec.ion, and gastric.c.eanliness. Results: Among the partic.pants, 24.2% had h. pylori infec.ion, and 17.5% had poor gastric.c.eanliness. hypertension (odds ratio [OR]: 2.63; 95% c.nfidenc. interval [c.]: 1.36–5.09; p = 0.004) was assoc.ated with a greater likelihood of h. pylori infec.ion. h. pylori infec.ion (OR: 3.76; 95% c.: 1.99–7.09; p c.or for poor gastric.c.eanliness in the Mc.G. A signific.nt disparity was noted in the prevalenc. of foc.l erosions (p c.ulc.rs (p = 0.001), and positive gastric.lesions (p = 0.027) between the 2 groups with and without h. pylori infec.ion. The proportion of positive gastric.lesions was not signific.ntly different between the good gastric.c.eanliness group and the poor gastric.c.eanliness group (25.7% vs. 21.2%; p = 0.490). c.nc.usion: The findings of this study revealed that h. pylori infec.ion was assoc.ated with hypertension. h. pylori infec.ion may lead to poor gastric.c.eanliness. Institutions are advised to perform c.3-UBT before Mc.G, and partic.pa

关键词： c.urea breath test Gastric.c.eanliness helic.bac.er pylori hypertension Magnetic.lly c.ntrolled c.psule gastrosc.py

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c.nstruc.ion of 2D/2D Ti_(3)c.(2)T_(x)MXene/c.S heteroj.nc.ion with photothermal effec. for effic.ent photoc.talytic.hydrogen produc.ion

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j.urnal of Materials Sc.enc. & Tec.nology 2024年第4期171卷 1-9页

作者： T.Y.h.ang Z.Yang S.Y.Yang Z.h.Dai Y.j.Liu j.h.Liao G.Y.Zhong Z.j.Xie Y.P.Fang S.S.Zhang Key Laboratory for Biobased Materials and Energy of Ministry of Educ.tion Guangdong Laboratory for Lingnan Modern AgricultureCollege of Materials and EnergySouth China Agricultural UniversityGuangzhou 510643China Sc.ool of Physic. and Optoelec.ronic. South China University of TechnologyGuangzhou 510640China Sc.ool of c.emic.l Engineering and Energy Tec.nology Guangdong Provincial Key Laboratory of Distributed Energy SystemsDongguan University of TechnologyDongguan 523808China

The insensitivity of semic.nduc.ors to visible and infrared light is a key c.nstraint on the utilization of light energy in photoc.talytic.*** photoc.talysts with full-spec.rum absorption through surfac. engineering is an effec.ive approac. to fully harnessing light energy in semic.nduc.or ***,a novel stable Ti_(3)c.(2)T_(x)MXene/c.S heteroj.nc.ion c.talyst is obtained by in-situ epitaxial growth of two-dimensional(2D)c.S nanosheets on 2D MXene interfac. via a solvothermal *** exc.ptional light absorption properties of MXene c.nfer outstanding full-spec.rum driven photoc.t-alytic.hydrogen evolution c.pability upon the heterogeneous *** unique 2D/2D struc.ure effec.ively mitigated the rec.mbination of photogenerated c.rriers,enhanc.ng the photoc.talytic.performanc. of the ***,the c.mposite c.talyst exhibits a signific.ntly higher surfac. temperature of 80.4℃under visible light irradiation at an intensity of 0.1 W/c.^(2),whic. is 1.84 times higher than that of *** irradiation of visible and near infrared light,the c.mposite c.talyst with photothermal ef-fec. demonstrates a remarkable hydrogen evolution rate of 65.4 mmol g^(-1)h^(-1),whic. is 7.2 times higher than that of c.S *** study introduc.s a novel approac. for c.nstruc.ing full-spec.rum absorption c.talysts and expands the applic.tion of the photothermal effec. in photoc.talytic.hydrogen evolution researc..

关键词： Two-dimensional struc.ure heterostruc.ure Photothermal effec. Photoc.talyst hydrogen evolution

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Molec.lar properties of dissolved organic.matter ac.oss Earth systems: A meta-analysis

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j.urnal of Earth Sc.enc. 2024年

作者： Lei han ang hu hellen Luc.s Mzuka Xingting c.en j. Shen j.anj.n Wang Key Laboratory of Lake and Watershed Sc.enc. for Water Sec.rity， Nanj.ng Institute of Geography and Limnology， c.inese Ac.demy of Sc.enc.s Sc.ool of Geography and Oc.an Sc.enc.， Nanj.ng University

Dissolved organic.matter （DOM） represents the largest pool of reac.ive c.rbon on the Earth and plays a c.uc.al role in various biogeoc.emic.l proc.sses and ec.system func.ions. however， it is understudied for a global understanding of DOM molec.lar properties suc. as molec.lar weight， stoic.iometry， and oxidation state， and the linkages among them ac.oss Earth systems. here， a meta-analysis of 2，707 sites in 204 literatures was c.nduc.ed by synthesizing four representative molec.lar properties of DOM， i.e.， mass， double bond equivalent （DBE）， modified aromatic.ty index (AImod)， and nominal oxidation state of c.rbon （NOSc.. By exploring h/c.and O/c.ratios， we examined the relationships among these DOM properties ac.oss waters and land systems， and their geographic.l patterns and environmental drivers. We found that， c.mpared to land system， the mass， DBE， and AImodwere all signific.ntly higher in water systems， with river sediments exhibiting the highest values. DOM oxidation state indic.ted by NOSc.was greater on average in wastewater （NOSc.= 0.226 ± 0.06） and marine water （NOSc.= 0.133 ± 0.06） than in other habitats. c.mpared to waters， the mass in land system showed more strongly positive c.rrelations with oxidation states suc. as NOSc.and O/c. and the NOSc.showed stronger relations to bioavailability properties suc. as DBE， AImod， and h/c. Among all the properties， h/c.and AImodc.ntributed to the most variations in global DOM properties. In waters， NOSc.monotonic.lly inc.eased towards high latitudes， while DBE and AImodshowed signific.nt hump-shaped patterns indic.ting peaked unsaturation and aromatic.ty at mid-latitudes of approximately absolute 30°-50°. The variations in DOM properties were signific.ntly c.rrelated with environmental fac.ors suc. as annual mean temperature and ph. c.llec.ively， we revealed the spatial distribution and environmental drivers of DOM molec.lar properties ac.oss Earth ec.systems， whic. c.uld shed light on our c.mprehensive understan

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c.4^(+)T c.lls produc. IFN-I to lic.nse c.c.s for induc.ion of c.totoxic.T-c.ll ac.ivity in human tumors

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c.llular & Molec.lar Immunology 2024年第4期21卷 374-392页

作者： Xin Lei Daniël c.de Groot Marij.j.P.Welters Tom de Wit Ellen Sc.rama hans van Eenennaam Saskia j.Santegoets Timo Oosenbrug Annemarthe van der Veen j.ris L.Vos c.arlotte L.Zuur Noel F.c.c.de Miranda heinz j.c.bs Sj.erd h.van der Burg j.nnie Borst Yanling Xiao Department of Immunology Leiden University Medical CenterLeidenThe Netherlands Onc.de Institute Leiden University Medical CenterLeidenThe Netherlands Department of Tumor Biology and Immunology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Medic.l Onc.logy Oncode InstituteLeiden University Medical CenterLeidenThe Netherlands IMMIOS B.V. OssThe Netherlands Division of Medic.l Onc.logy The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Otorhinolaryngology Leiden University Medic.l c.nter LeidenThe Netherlands Department of Pathology Leiden University Medical CenterLeidenThe Netherlands

c.4^(+)T c.lls c.n"help"or"lic.nse" c.nventional type 1 dendritic.c.lls(c.c.s)to induc. c.8^(+)c.totoxic.T lymphoc.te(c.L)antic.nc.r responses,as proven in mouse *** rec.ntly identified c.c.s with a transc.iptomic.imprint of c.4^(+)T-c.ll help,spec.fic.lly in T-c.ll-infiltrated human c.nc.rs,and these c.lls were assoc.ated with a good prognosis and response to PD-1-targeting ***,we delineate the mec.anism of c.c. lic.nsing by c.4^(+)T c.lls in *** c.4^(+)T c.lls produc. IFNβvia the STING pathway,whic. promotes Mhc.I antigen(c.oss-)presentation by c.c.s and thereby improves their ability to induc. c.L antic.nc.r *** c.operation with c.40 ligand(L),IFNβalso optimizes the c.stimulatory and other func.ions of c.c.s required for c.L response ***-I-produc.ng c.4^(+)T c.lls are present in diverse T-c.ll-infiltrated c.nc.rs and likely deliver“help”signals to c.Ls loc.lly,ac.ording to their transc.iptomic.profile and c.loc.lization with“helped/lic.nsed”c.c. and tumor-reac.ive c.8^(+)T *** agreement with this sc.nario,the presenc. of IFN-I-produc.ng c.4^(+)T c.lls in the TME is assoc.ated with overall survival and the response to PD-1 c.ec.point bloc.ade in c.nc.r patients.

关键词： c.4^(+)T-c.ll help c.c. lic.nsing IFN-I signaling c.40 c.stimulation (c.oss-)presentation c.L priming Tumor c.ntrol

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Resilienc., the 6th Vital Sign: c.nc.ptualizing, c.ntextualizing, and Operationalizing All Six Vital Signs

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health 2024年第7期16卷 657-673页

作者： Rose E. c.nstantino Betty j. Braxter c.i c.ing Vivian hui Larissa c. Allen Lillian j. Wolfe Katherine h. Endres j.zyl c.mpron c.tamora Laurenc. L. Garc.a Daisy R. Palompon Kathleen Thimsen Brayden N. Kameg Margarete L. Zalon Department of health and c.mmunity Systems School of Nursing University of Pittsburgh Pittsburgh PA USA Undergraduate Affairs School of Nursing University of Pittsburgh Pittsburgh PA USA The hong Kong Polytec.nic.University Hong Kong China Sc.ool of Nursing Adjunct Faculty at the University of Pittsburgh Pittsburgh PA USA Sc.ool of Nursing University of Pittsburgh Pittsburgh PA USA Department of health Promotion and Development School of Nursing University of Pittsburgh Pittsburgh PA USA c.llege of Nursing Cebu Normal University Cebu City Philippines Sc.ool of Nursing University of Nevada Las Vegas USA Department of health and c.mmunity Systems University of Pittsburgh PA USA Department of Nursing University of Scranton Scranton PA USA

There are five vital signs that healthc.re providers assess: temperature, pulse, respiration, blood pressure, and pain. Normal levels for the five vital signs are published by the Americ.n heart Assoc.ation, and other spec.alty organizations, however, the sixth vital sign (resilienc.) whic. adopts the measure of immune resilienc. is suggested in this paper. Resilienc. is the ability of the immune system to respond to attac.s and defend effec.ively against infec.ions and inflammatory stressors, and psyc.ologic.l resilienc. is the c.pac.ty to resist, adapt, rec.ver, thrive, and grow from a c.allenge or a stressor. Individuals with better optimal immune resilienc. had better health outc.mes than those with minimal immune resilienc.. The purpose of this paper is to c.nc.ptualize, c.ntextualize, and operationalize all six vital signs. We suggest measuring resilienc. subj.c.ively and obj.c.ively. Subj.c.ively, use a 5-item guided interview revised from the c.nnor-Davidson Resilienc. Sc.le (c.Rc., a sc.le of 10 items. The revised c.Rc.sc.le is a 5-item sc.le. The sc.le is rated on a 5-point Likert sc.le from 0 (not true) to 4 (true all the time). The total sc.re ranges from 0 to 20, with higher total sc.res indic.ting greater resilienc.. The sc.le demonstrated good c.nstruc. validity and internal c.nsistenc. (α = 0.85) during the development of the sc.le. The c.-RISc.had a good c.onbac.’s alpha level of 0.85. The Revised c.-RISc.c.n be c.mpleted in 2 - 4 minutes. To measure resilienc. obj.c.ively, we suggest using Immune Resilienc. (IR) levels, the level of resilienc. to preserve and/or rapidly restore immune resilienc. func.ions that promote disease resistanc. and c.ntrol inflammation and other inflammatory stress. IR levels are gauged with two peripheral blood metric. that quantify the balanc. between c.8 and c.4 T-c.ll levels and gene expression signatures trac.ing longevity-assoc.ated immunoc.mpetenc. and mortality- or entropy-assoc.ated inflammation. IR deregulation i

关键词： c.nc.ptualization c.ntextualization Operationalization Body Temperature Pulse Respiration Blood Pressure Pain Resilienc.

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STc. c.nc.ptual design report (Volume 1): Physic. & detec.or

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Frontiers of physic. 2024年第1期19卷 1-154页

作者： M.Ac.asov X.c.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.h.Bu F.M.c.i h.c.i j.j.c.o Q.h.c.o X.c.o Z.c.o Q.c.ang K.T.c.ao D.Y.c.en h.c.en h.X.c.en j.F.c.en K.c.en L.L.c.en P.c.en S.L.c.en S.M.c.en S.c.en S.P.c.en W.c.en X.c.en X.F.c.en X.R.c.en Y.c.en Y.Q.c.en h.Y.c.eng j.c.eng S.c.eng T.G.c.eng j.P.Dai L.Y.Dai X.c.Dai D.Dedovic. A.Denig I.Denisenko j.M.Dias D.Z.Ding L.Y.Dong W.h.Dong V.Druzhinin D.S.Du Y.j.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.j.Fang G.Fedotovic. c.Q.Feng X.Feng Y.T.Feng j.L.Fu j.Gao Y.N.Gao P.S.Ge c.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl j.L.Gu A.Guevara L.c.Gui A.Q.Guo F.K.Guo j.c.Guo j.Guo Y.P.Guo Z.h.Guo A.Guskov K.L.han L.han M.han X.Q.hao j.B.he S.Q.he X.G.he Y.L.he Z.B.he Z.X.heng B.L.hou T.j.hou Y.R.hou c.Y.hu h.M.hu K.hu R.j.hu W.h.hu X.h.hu Y.c.hu j.hua G.S.h.ang j.S.h.ang M.h.ang Q.Y.h.ang W.Q.h.ang X.T.h.ang X.j.h.ang Y.B.h.ang Y.S.h.ang N.hüsken V.Ivanov Q.P.j. j.j.j.a S.j.a Z.K.j.a h.B.j.ang j.j.ang S.Z.j.ang j.B.j.ao Z.j.ao h.j.j.ng X.L.Kang X.S.Kang B.c.Ke M.Kenzie A.Khoukaz I.Koop E.Kravc.enko A.Kuzmin Y.Lei E.Levic.ev c.h.Li c.Li D.Y.Li F.Li G.Li G.Li h.B.Li h.Li h.N.Li h.j.Li h.L.Li j.M.Li j.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.h.Li S.Li T.Li W.j.Li X.Li X.h.Li X.Q.Li X.h.Li Y.Li Y.Y.Li Z.j.Li h.Liang j.h.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao c.X.Lin D.X.Lin X.S.Lin B.j.Liu c.W.Liu D.Liu F.Liu G.M.Liu h.B.Liu j.Liu j.j.Liu j.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long c.G.Lu j.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.j.Luo T.Luo X.F.Luo Y.h.Luo h.j.Lyu X.R.Lyu j.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitc.ell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei h.P.Peng L.Peng X.Y.Peng X.j.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian c.F.Qiao j.j.Qin j.j.Qin L.Q.Qin X.S.Qin T.L.Qiu j.Rademac.er c.F.Redmer h.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuc.ear Physic. Novosibirsk 630090Russia c.S Key Laboratory of Theoretic.l Physic. Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China c.vendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom c.ntral c.ina Normal University Wuhan 430079China c.ntral South University Changsha 410083China c.ina University of Geosc.enc.s Wuhan 430074China c.ina University of Mining and Tec.nology Xuzhou 221116China Éc.le Polytec.nique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China hangzhou Institute for Advanc.d Study UCASHangzhou 310024China hebei Normal University Shijiazhuang 050024China hebei University Baoding 071002China hefei University of Tec.nology Hefei 230601China helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China high Energy Physic. c.nter Chung-Ang UniversitySeoul 06974Korea higher Sc.ool of Ec.nomy 11 Pokrovsky Bulvar Moscow 109028Russia h.angshan University Huangshan 245000China hubei University of Automotive Tec.nology Shiyan 442002China hunan Normal University Changsha 410081China hunan University of Sc.enc. and Tec.nology Xiangtan 411201China hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanc.d Sc.enc. Fac.lities Shenzhen 518107China Institute of high Energy Physic. Chinese Academy of SciencesBeijing 100049China Institute of Modern Physic. Chinese Academy of SciencesLanzhou 730000China Institute of Physic. Academia SinicaTaipeiTaiwan 11529China Institute of Theoretic.l Physic. Chinese Academy of SciencesBeijing 100190China j.lin University Changch

The superτ-c.arm fac.lity(STc.)is an elec.ron–positron c.llider proposed by the c.inese partic.e physic. *** is designed to operate in a c.nter-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) c.^(–2)·s^(–1) or *** STc. will produc. a data sample about a fac.or of 100 larger than that of the presentτ-c.arm fac.ory—the BEPc.I,providing a unique platform for exploring the asymmetry of matter-antimatter(c.arge-parity violation),in-depth studies of the internal struc.ure of hadrons and the nature of non-perturbative strong interac.ions,as well as searc.ing for exotic.hadrons and physic. beyond the Standard *** STc. proj.c. in c.ina is under development with an extensive R&D *** doc.ment presents the physic. opportunities at the STc.,desc.ibes c.nc.ptual designs of the STc. detec.or system,and disc.sses future plans for detec.or R&D and physic. c.se studies.

关键词： elec.ron–positron c.llider tau-c.arm region high luminosity STc. detec.or c.nc.ptual design

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Morphologic.l disruption and visual tuning alterations in the primary visual c.rtex in glauc.ma(DBA/2j.mic.

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Neural Regeneration Researc. 2024年第1期19卷 220-225页

作者： Yin Yang Zhaoxi Yang Maoxia Lv ang j.a j.nj.n Li Baitao Liao j.ng’an c.en Zhengzheng Wu Yi Shi Yang Xia Dezhong Yao Ke c.en Department of Ophthalmology Sichuan Provincial People’s HospitalMedical SchoolUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina The c.inic.l hospital of c.engdu Brain Sc.enc. Institute MOE Key Lab for NeuroInformationSchool of Life Science and TechnologyUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Researc. Unit of NeuroInformation Chinese Academy of Medical SciencesChengduSichuan ProvinceChina Institute of Basic.Medic.l Sc.enc.s c.inese Ac.demy of Medic.l Sc.enc.s School of Basic Medicine Peking Union Medical CollegeBeijingChina health Management c.nter Sichuan Provincial Key Laboratory for Human Disease Gene StudySichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Researc. Unit for Blindness Prevention of c.inese Ac.demy of Medic.l Sc.enc.s(2019RU026) Sichuan Academy of Medical SciencesChengduSichuan ProvinceChina Sc.ool of Elec.ric.l Engineering Zhengzhou UniversityZhengzhouHenan ProvinceChina

Glauc.ma is a leading c.use of irreve rsible blindness wo rldwide,and previous studies have shown that,in addition to affec.ing the eyes,it also c.uses abnormalities in the ***,it is not yet c.ear how the primary visual c.rtex(V1)is altered in *** study used DBA/2j.mic. as a model for spontaneous sec.ndary *** aim of the study was to c.mpare the elec.rophysiologic.l and histomorphologic.l c.ara c.eristic. of neurons in the V1between 9-month-old DBA/2j.mic. and age-matc.ed c.7BL/6j.*** c.nduc.ed single-unit rec.rdings in the V1 of light-anesthetized mic. to measure the visually induc.d responses,inc.uding single-unit spiking and gamma band *** morphology of layerⅡ/Ⅲneurons was determined by neuronal nuc.ear antigen staining and Nissl staining of brain tissue ***-seven neurons from eight DBA/2j.mic. and eighty-one neurons from eight c.7BL/6j.mic. were *** with the c.7BL/6j.group,V1 neurons in the DBA/2j.group exhibited weaker visual tuning and impaired spatial *** r,fewer neuro ns were observed in the V1 of DBA/2j.mic. c.mpared with c.7BL/6j.*** findings suggest that DBA/2j.mic. have fewer neurons in the VI c.mpared with c.7BL/6j.mic.,and that these neurons have impaired visual *** findings provide a better understanding of the pathologic.l c.anges that oc.ur in V1 neuron func.ion and morphology in the DBA/2j.mouse *** study might offer some innovative perspec.ives regarding the treatment of glauc.ma.

关键词： DBA/2j degeneration gamma band osc.llations glauc.ma primary visual c.rtex(V1) retina single-unit rec.rding tuning c.rve

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Sync.ronized off-harmonic.probe laser with highly variable pulse duration for laser-plasma interac.ion experiments

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high Power Laser Sc.enc. and Engineering 2024年第1期12卷 99-107页

作者： j.hornung Y.Zobus h.Lorenté c.Brabetz B.Zielbauer V.Bagnoud GSI helmholtzzentrum für Sc.werionenforsc.ung Gmbh DarmstadtGermany Institut d’Optique UniversitéParis-SaclayPalaiseauFrance Institut für angewandte Physik Technische Universität DarmstadtDarmstadtGermany

This paper presents the development and experimental utilization of a sync.ronized off-harmonic.laser system designed as a probe for ultra-intense laser±plasma interac.ion experiments. The system exhibits a novel seed-generation design,allowing for a variable pulse duration spanning over more than three orders of magnitude, from 3.45 pic.sec.nds to 10 nanosec.nds. This makes it suitable for various plasma diagnostic. and visualization tec.niques. In a side-view c.nfiguration, the laser was employed for interferometry and streaked shadowgraphy of a laser-induc.d plasma while suc.essfully suppressing the self-emission bac.ground of the laser±plasma interac.ion, resulting in a signal-to-self-emission ratio of 110 for this setup. These properties enable the probe to yield valuable insights into the plasma dynamic. and interac.ions at the PhELIX fac.lity and to be deployed at various laser fac.lities due to its easy-to-implement design.

关键词： interferometry laser-plasma interac.ion off-harmonic.probe laser streaked shadowgraphy

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c.mparisons of oxbow lake fish assemblages in relation to bigheaded c.rp establishment in the lower White River, Arkansas

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Ec.logic.l Proc.sses 2024年第1期13卷 188-205页

作者： Mic.ael A.Eggleton c.dy j.Salzmann j.seph E.Kaiser Shannon c.F.Smith Department of Aquac.lture and Fisheries University of Arkansas at Pine Bluff Arkansas Game and Fish c.mmission Virginia Institute of Marine Sc.enc.

Bac.ground Sinc. the late 1990s, bigheaded c.rps(largely silver c.rp [hypophthalmic.thys molitrix] but also bighead c.rp [h. nobilis]) have established throughout the lower Mississippi River basin. Using previously studied oxbow lakes in the lower White River basin, Arkansas, we c.mpared c.rrent(2017, “post-c.rp” establishment) fish assemblages to historic.l(2002, “pre-c.rp” establishment) fish assemblages. Fish assemblages were c.mprehensively assessed using multiple gears, inc.uding boat elec.rofishing, mini-fyke nets, and experimental small-mesh gill *** T-tests suggested that fish assemblage indic.s of ric.ness, diversity, evenness, and dominanc. were often greater(P he post-c.rp period as reflec.ed by boat elec.rofishing and experimental gill nets. however, all indic.s were generally similar(P > 0.05) between the pre-c.rp and post-c.rp period with fish assemblages depic.ed using mini-fyke nets. Nonmetric.multidimensional sc.ling analyses indic.ted that fish assemblages differed struc.urally between pre-c.rp and post-c.rp periods. Assemblage differenc.s were linked to both small and large abundanc. c.anges for more than 20 spec.es. Abundanc.s of gizzard shad(Dorosoma c.pedianum), emerald shiner(Notropis atherinoides), pugnose minnow(Opsopoeodus emiliae), c.appies(Pomoxis spp.), bluegill(Lepomis mac.oc.irus), orangespotted sunfish(L. humilis), and yellow bass(Morone mississippiensis) dec.ined between the pre-c.rp and postc.rp periods. c.nversely, abundanc.s of weed shiner(N. texanus), pallid shiner(hybopsis amnis), longear sunfish(L. megalotis), buffalofishes(Ic.iobus spp.), and gars(Lepisosteus spp.) generally inc.eased during the same *** Although not possible to c.nc.ude assemblage shifts were entirely related to bigheaded c.rps due to the absenc. of an appropriate referenc. system where c.rps did not establish, the wide establishment of these c.rps is one of the most pervasive c.anges to have oc.urred in the lower White

关键词： Bigheaded c.rp Silver c.rp Aquatic.nuisanc. spec.es Fish assemblage Oxbow lake Large river

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