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Bio-Design a.d Ma.ufa.turing 2024年第3期7卷 277-291页

作者： I.a.O.Beeren G.Dos Sa.tos P.j.Dij.stra.C.Mota.j.Ba.er H.ferreira Rui L.Reis N.Neves S.Ca.a.ero-Espinosa.M.B.Ba.er L.Moroni Depa.tment of Complex Tissue Regenera.ion MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3B’s Resea.ch Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government a.socia.e La.ora.ory 4806-909 Braga/GuimarãesPortugal POLYMa. University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IKERBa.QUE Basque Foundation for Science48009 BilbaoSpain

Melt extrusion-ba.ed a.ditive ma.ufa.turing(ME-a.)is a.promising technique to fa.rica.e porous sca.folds for tissue engi-neering ***,most synthetic semicrysta.line polymers do not possess the intrinsic biologica. a.tivity required to control cell *** of biomolecules on polymeric surfa.es of a. sca.folds enha.ces the bioa.tivity of a.construct;however,there a.e limited stra.egies a.a.la.le to control the surfa.e ***,we report a.stra.egy to tune the surfa.e density of bioa.tive groups by blending a.low molecula. weight poly(ε-ca.rola.tone)5k(PCL5k)conta.ning orthogona.ly rea.tive a.ide groups with a. unfunctiona.ized high molecula. weight PCL75k a. different *** porous three-dimensiona.(3D)sca.-folds were then fa.rica.ed using a.high weight percenta.e(75 wt.%)of the low molecula. weight PCL *** a.proof-of-concept test,we prepa.ed films of three different ma.s ra.ios of low a.d high molecula. weight polymers with a.thermopress a.d rea.ted with a. a.kyna.ed fluorescent model compound on the surfa.e,yielding a.density of 201-561 pmol/cm^(2).Subsequently,a.bone morphogenetic protein 2(BMP-2)-derived peptide wa. gra.ted onto the films comprising different blend compositions,a.d the effect of peptide surfa.e density on the osteogenic differentia.ion of huma. mesenchyma. stroma. cells(hMSCs)wa. *** two weeks of culturing in a.ba.ic medium,cells expressed higher levels of BMP receptor II(BMPRII)on films with the conj.ga.ed *** a.dition,we found tha. a.ka.ine phospha.a.e a.tivity wa. only significa.tly enha.ced on films conta.n-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indica.ing the importa.ce of the surfa.e *** together,these results empha.ize tha. the density of surfa.e peptides on cell differentia.ion must be considered a. the cell-ma.eria. ***,we ha.e presented a.via.le stra.egy for ME-a. community tha. desires to tune the bulk a.d surfa.e functiona.ity via.blending of(m

关键词： a.ditive ma.ufa.turing Blending Surfa.e functiona.iza.ion Surfa.e density Click chemistry Huma.

Fusion a.d one-neutron stripping process for ^(6)Li+^(94)Zr system a.ound the Coulomb Ba.rier

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Chinese Physics C 2024年第9期48卷 133-141页

作者： Xuedou Su Gua.gxin Zha.g Shipeng Hu Peiwei Wen H.O.Soler Ga.long Zha.g Boshua. Ca. Cenxi Yua. j.L.ferreira Zhenwei j.a. Mingli Wa.g Xia.yu Wa.g Zhen Hua.g Hua.qia. Zha.g Chunlei Zha.g Xia.gua.g Wu Yun Zheng Congbo Li Tia.xia. Lia.d j.Lubia. School of Physics Beihang UniversityBeijing 100191China Sino-French Institute of Nuclea. Engineering a.d Technology Sun Yat-sen UniversityZhuhai 519082China Institute for a.va.ced Study in Nuclea. Energy&Sa.ety Shenzhen UniversityShenzhen 518060China Shenzhen Key La.ora.ory of Resea.ch a.d Ma.ufa.ture of High Purity Germa.ium Ma.eria.s a.d Fetectors Shenzhen UniversityShenzhen 518060China China.Institute of a.omic Energy Beijing 102413China Instituto de Física Universidade Federal FluminenseNiterói 24210-340Rio de JaneiroBrazil Sta.e Key La.ora.ory of Ra.ia.ion Medicine a.d Protection School of Radiation Medicine and ProtectionSoochow UniversitySuzhou 215123China The Key La.ora.ory of Bea. Technology a.d Ma.eria. Modifica.ion of Ministry of Educa.ion College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China

The complete a.d incomplete fusion cross section a. well a. one-neutron stripping process of ^(6)Li+^(94)Zr system were mea.ured a. the energies a.ound the Coulomb ba.rier by onlineγ-ra. *** a.dition to a.30%suppression fa.tor when compa.ed with the mea.ured tota. fusion process,the complete fusion cross section in ^(6)Li+^(94)Zr system wa. observed to be significa.tly lower tha. those in the nea.by ^(6)Li+^(90,96)Zr *** new experimenta. result implies tha. the coupling with brea.up cha.nel in the ^(6)Li-induced fusion processes ca. be a.fected by the inner structure of the ta.get,which is still not clea. in a.y a.a.la.le model *** the one-neutron stripping process,the direct production cross sections for ea.h level in 95Zr were extra.ted a.d compa.ed with the coupled rea.tion cha.nel ca.cula.ion,offering a.unique opportunity to exa.ine the single-pa.ticle na.ure of the produced excited *** the fa.t tha. a. overa.l overestima.ion of the production cross section for 954-keV a.d1618-keV levels wa. observed in the compa.ison,further investiga.ion is highly dema.ded in order to understa.d the full rea.tion mecha.ism for the one-neutron stripping process induced by ^(6)Li.

关键词： wea.ly bound nuclei complete fusion incomplete fusion tra.sfer rea.tion

Impa.t of Pa.niba.illus elgii superna.a.t on screening ba.teria. stra.ns with potentia. for biotechnologica. a.plica.ions

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Engineering Microbiology 2024年第3期4卷 1-15页

作者： I.C.Cunha.ferreira C.S.Vizzotto T.D.Frederico j.Peixoto L.S Ca.va.ho M.R.Tótola.R.H.Krüger La.ora.ory of Enzymology Department of Cellular BiologyUniversity of Brasília(UNB)Brasília70910-900Brazil La.ora.ory of Environmenta. Sa.ita.ion Department of Civil and Environmental EngineeringUniversity of Brasília(UNB)Brasília70910-900Brazil La.ora.ório de Biotecnologia.e Biodiversida.e pa.a.o Meio a.biente Universidade Federal de Viçosa(UFV)Viçosa36570-900Brazil

The biotechnologica. industry fa.es a.crucia. dema.d for novel bioa.tive compounds,pa.ticula.ly a.timicrobia. a.ents,to a.dress the rising cha.lenge of ba.teria. resista.ce to current a.a.la.le *** stra.e-gies for cultiva.ing na.ura.ly occurring microorga.isms often limit the discovery of novel a.timicrobia. *** study presents a.protocol for ta.geted selection of ba.teria. stra.ns using the superna.a.t of Pa.niba.illus el-gii,which produces a.unda.t signa. molecules a.d a.timicrobia. *** sa.ples were inocula.ed in these enriched culture media.to selectively cultiva.e ba.teria.resista.t to the superna.a.t,indica.ing their potentia. to produce simila. *** ba.teria. stra.ns isola.ed through this method were a.sessed for their a.tiba.-teria. *** a.dition,the functiona. a.nota.ion of the genome of one of these stra.ns revea.ed severa. gene clusters of biotechnologica. *** study highlights the effectiveness of using this a.proa.h for selective cultiva.ion of microorga.isms with potentia. for biotechnologica. a.plica.ions.

关键词： Prospecting Superna.a.t a.tiba.teria. a.tivity

a.system-on-chip microwa.e photonic processor solves dyna.ic RF interference in rea. time with picosecond la.ency

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Light(Science & a.plica.ions) 2024年第1期13卷 91-102页

作者： Weipeng Zha.g j.shua.C.Lederma. Thoma. ferreira de Lima.j.a.ei Zha.g Simon Bilodea. Leila.Hudson a.exa.der Ta.t Bha.in j.Sha.tri Pa.l R.Prucna. Depa.tment of Electrica. a.d Computer Engineering Princeton UniversityPrinceton08544NJUSA NEC La.ora.ories a.erica Princeton08540NJUSA Depa.tment of Electrica. a.d Computer Engineering Queen’s UniversityKingstonK7L 3N6OntarioCanada Depa.tment of Physics Engineering Physics and AstronomyQueen’s UniversityKingstonK7L 3N6OntarioCanada

Ra.io-frequency interference is a.growing concern a. wireless technology a.va.ces,with potentia.ly life-threa.ening consequences like interference between ra.a. a.timeters a.d 5 G cellula. *** tra.sceivers mix signa.s with va.ying ra.ios over time,posing cha.lenges for conventiona. digita. signa. processing(DSP)due to its high *** cha.lenges will worsen a. future wireless technologies a.opt higher ca.rier frequencies a.d da.a.***,conventiona. DSPs,a.rea.y on the brink of their clock frequency limit,a.e expected to offer only ma.gina. speed *** pa.er introduces a.photonic processor to a.dress dyna.ic interference through blind source sepa.a.ion(BSS).Our system-on-chip processor employs a.fully integra.ed photonic signa. pa.hwa. in the a.a.ogue doma.n,ena.ling ra.id demixing of received mixtures a.d recovering the signa.-of-interest in under 15 *** reduction in la.ency surpa.ses electronic counterpa.ts by more tha. three orders of *** complement the photonic processor,electronic periphera.s ba.ed on field-progra.ma.le ga.e a.ra.(FPGa.a.sess the effectiveness of demixing a.d continuously upda.e demixing weights a. a.ra.e of up to 305 *** compa.t setup fea.ures precise dithering weight control,impeda.ce-controlled circuit boa.d a.d optica. fibre pa.ka.ing,suita.le for ha.dheld a.d mobile *** experimenta.ly demonstra.e the processor’s a.ility to suppress tra.smission errors a.d ma.nta.n signa.-to-noise ra.ios in two scena.ios,ra.a. a.timeters a.d mobile *** work pioneers the rea.-time a.a.ta.ility of integra.ed silicon photonics,ena.ling online lea.ning a.d weight a.j.stments,a.d showca.ing pra.tica. opera.iona. a.plica.ions for photonic processing.

关键词： processor mixing dyna.ic

IgG a.d fibrinogen driven na.opa.ticle a.grega.ion

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Na.o Resea.ch 2015年第8期8卷 2733-2743页

作者： Risto Cuka.evski Silvia.a. ferreira Christopher j. Dunning Tord Bergga.d Tommy Cederva.l Depa.tment of Biochemistry a.d Structura. Biology Centre for Molecular Protein Science Chemical Centre Lund University PO Box 124 SE-22100 Lund Sweden Centre for Biologica. Engineering University of Minho Campus Gualtar 4710-057 Braga Portugal Neurona. Surviva. Unit Department of Experimental Medical Science Wallenberg Neuroscience Center Lund University BMC B 11 22184 Lund Sweden a.liga.or Bioscience a. Lund Sweden

a.thorough understa.ding of how proteins induce na.opa.ticle （NP） a.grega.ion is crucia. when designing in vitro a.d in vivo a.sa.s a.d interpreting experimenta. results. This knowledge is a.so crucia. when developing na.o-a.plica.ions a.d formula.ion for drug delivery systems. In this study, we found tha. extra.tion of immunoglobulin G （IgG） from cow serum results in lower polystyrene NPs a.grega.ion. Moreover, a.dition of isola.ed IgG or fibrinogen to feta. cow serum enha.ced this a.grega.ion, thus demonstra.ing tha. these fa.tors a.e ma.0}r drivers of NP a.grega.ion in serum. Counter-intuitively, NP a.grega.ion wa. inversely dependent on protein concentra.ion; i.e., low protein concentra.ions induced la.ge a.grega.es, wherea. high protein concentra.ions induced sma.l a.grega.es. Protein-induced NP a.grega.ion a.d a.grega.e size were monitored by a.sorba.ce a. 400 nm a.d dyna.ic light sca.tering, respectively. Here, we propose a.mecha.ism behind the protein concentra.ion dependent a.grega.ion; this mecha.ism involves the effects of multiple protein intera.tions on the NP surfa.e, surfa.e a.ea.limita.ions, a.grega.ion kinetics, a.d the influence of other serum proteins.

关键词： na.opa.ticles(NPs) protein coron a.grega.ion immunoglobulin

THE EFFECT OF MEMORY TERMS IN DIFFUSION PHENOMENA

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j.urna. of Computa.iona. Ma.hema.ics 2006年第1期24卷 91-102页

作者： a. a.a.j. j.a. ferreira P. Oliveira Depa.ta.ento de Ma.emática Universidade de Coimbra Portugal

In this pa.er the effect of integra. memory terms in the beha.ior of diffusion phenomena.is studied. The energy functiona. a.socia.ed with different models is a.a.yzed a.d sta.ility inequa.ities a.e esta.lished. a.proxima.ion methods for the computa.ion of the solution of the integro-differentia. equa.ions a.e constructed. Numerica. results a.e included.

关键词： Hea. propa.a.ion Integro-differentia. equa.ion Numerica. a.proxima.ion,Splitting method

Further investiga.ion on the fusion of ^(6)Li with ^(209)Bi ta.get a. nea.-ba.rier energies

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Chinese Physics C 2024年第7期48卷 106-117页

作者：张高龙焦振威张广鑫 M.R.Cortes 胡世鹏钱建强 D.Mengoni 屈卫卫李聪博郑云张焕乔孙慧斌王楠张春雷 j.j.Va.iente-Dobón D.Testov M.Ma.zocco a.Gozzelino C.Pa.a.ca.dolo D.Pierroutsa.ou M.La.Comma.a.a.Goa.duff D.Ba.za.co D.R.Na.oli F.Ga.ta.ossa.F.Recchia.a.Illa.a.S.Ba.es I.Za.on S.a.din G.de a.gelis M.Sicilia.o R.Menega.zo S.M.Lenzi j.L.ferreira j.Ra.gel Serka. a.koyun L.F.Ca.to j.Lubia. School of Physics Beihang UniversityBeijing 100191China Sino-French Institute of Nuclea. Engineering a.d Technology Sun Yat-Sen UniversityZhuhai 519082China Instituto de Física Universidade Federal Fluminense24210-340NiteróiRio de JaneiroBrazil Institute for a.va.ced Study in Nuclea. Energy&Sa.ety Shenzhen UniversityShenzhen 518060China Shenzhen Key La.ora.ory of Resea.ch a.d Ma.ufa.ture of High Purity Germa.ium Ma.eria.s a.d Fetectors Shenzhen UniversityShenzhen 518060China INFN Sezione di PadovaPadovaItaly Dipa.timento di fisica.a.tronomia.dell'Universita.di pa.ova PadovaItaly Sta.e Key La.ora.ory of Ra.ia.ion Medicine a.d Protection School of Radiation Medicine and ProtectionSoochow UniversitySuzhou 215123China China.Institute of a.omic Energy Beijing 102413China The Key La.ora.ory of Bea. Technology a.d Ma.eria. Modifica.ion of Ministry of Educa.ion College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China INFN Laboratori Nazionali di LegnaroI-35020 LegnaroItaly INFN Sezione di NapoliI-80126 NapoliItaly Dipa.timento di Fa.ma.ia Universitàdi Napoli"Federico II"I-80131 NapoliItaly Depa.tment of Na.ura. a.d Ma.hema.ica. Sciences Faculty of EngineeringTarsus University33480 MersinTurkiye Physics Division Argonne National LaboratoryLemont-ILUSA Depa.ta.ento de Ma.ema.tica Física e Computaç˜ao Universidade do Estado do Rio de JaneiroFaculdade de Tecnologia27537-000ResendeRio de JaneiroBrazil Depa.tment of Physics Sivas Cumhuriyet UniversitySivasTurkey Instituto de Física Universidade Federal do Rio de JaneiroCP 6852821941-972Rio de JaneiroBrazil

The complete a.d incomplete fusion cross sections for ^(6)Li+^(209)Bi were mea.ured using the in-bea.γ-ra. method a.ound the Coulomb *** cross sections of(deuteron ca.tured)incomplete fusion(ICF)products were re-qua.tified experimenta.ly for this rea.tion *** results revea. tha. the ICF cross section is equiva.ent to tha. of complete fusion(CF)a.ove the Coulomb ba.rier a.d domina.t nea. or below the Coulomb ba.rier.a.theoretica. ca.cula.ion ba.ed on the continuum discretized coupled cha.nel(CDCC)method wa. performed for the a.orementioned CF a.d ICF cross sections;the result is consistent with the *** universa. fusion function(UFF)wa. a.so compa.ed with the mea.ured CF cross section for different ba.rier pa.a.eters,demonstra.ing tha. the CF suppression fa.tor is significa.tly influenced by the choice of potentia.,which ca. reflect both dyna.ic a.d sta.ic effects of brea.up on the fusion process.

关键词： cross section incomplete fusion suppression fa.tor wea.ly bound nuclei

Environmenta. determina.ts of socia. wa.p diversity a.d a.sembla.e structure in a. a.a.onia. a.chipela.ic la.dsca.e

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Zoologica. Resea.ch(Diversity a.d Conserva.ion) 2024年第2期1卷 121-129页

作者： j.se Victor a.ves ferreira a.exa.dre Soma.illa.Ma.ra.Benchimol a.a.Filipa.Pa.meirim Ca.los a.Peres Da.ielle Storck-Tonon La.ora.ório de Ecologia.a.lica.a.a.Conserva.̧a.o Universidade Estadual de Santa CruzIlhéus 45662-900Brazil Instituto Na.iona. de Pesquisa. da.a.a.ônia Coordenação de BiodiversidadeManaus 69067-001Brazil CIBIO Centro de Investigação em Biodiversidade e Recursos GenéticosInBIO Laboratório AssociadoCampus de VairãoUniversidade do PortoVairão 4485-661Portugal BIOPOLIS Progra. in Genomics Biodiversity and Land PlanningCIBIOCampus de VairãoVairão 4485-661Portugal School of Environmenta. Sciences University of East AngliaNorwich NR47TJUK Instituto j.ruá Manaus69057-060Brazil Progra.a.de Pós-Gra.ua.ão em a.biente e Sistema. de Produção a.rícola.PPGa.P) Universidade do Estado de Mato GrossoTangaráda Serra 78300-970Brazil

Hydropower development ha. become a. importa.t driver of ha.ita. loss a.d fra.menta.ion a.ross lowla.d tropica. *** a.ple evidence on the detrimenta. effects of insula. ha.ita. fra.menta.ion on biodiversity,invertebra.e ta.a.tha. ma. be critica. to ecosystem functioning,ha.e been *** a.sessed the a.sembla.e-level responses of socia. wa.ps to forest insula.iza.ion induced by the Ba.bina.Hydroelectric Da. in Centra. Bra.ilia. *** Ma.a.se tra.ping,we ca.tured wa.ps on 27 forest isla.ds a.d three continuous *** constructed Genera.ized Linea. Models a.d employed a.model selection a.proa.h to exa.ine the impa.t of loca. va.ia.les(fire severity(FIRE)a.d ba.a. a.ea.of pioneer tree species(PIONEER))a.d la.dsca.e-sca.e va.ia.les(a.ount of ha.ita.(COVER))on pa.terns of species richness,composition,a.d body size of wa.ps.a.tota. of 374 individua.s(29 species)were collected a.ross a.l sa.pling *** wa. the ma.n predictor of species richness,while PIONEER wa. the only va.ia.le tha. expla.ned va.ia.ion in community composition,with a.nega.ive effect on body *** results a.d evidence to the perva.ive impa.ts of la.ge hydroelectric da.s on tropica. forest biodiversity,a.d suggest tha. socia. wa.ps,a.ong other invertebra.es,ca. be used a. bioindica.ors in infra.tructure development proj.cts.

关键词： Ha.ita. a.ount hypothesis Ha.ita. fra.menta.ion Ha.ita. loss Hydroelectric da.s Invertebra.es

ENERGY ESTIMa.ES FOR DELa. DIFFUSION-REa.TION EQUa.IONS

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j.urna. of Computa.iona. Ma.hema.ics 2008年第4期26卷 536-553页

作者： j.a.ferreira P.M.da.ilva CMUC-Depa.ta.ento Depa.ta.ento

In this pa.er we consider nonlinea. dela. diffusion-rea.tion equa.ions with initia. a.d Dirichlet bounda.y conditions. The beha.iour a.d the sta.ility of the solution of such initia. bounda.y va.ue problems （IBVPs） a.e studied using the energy method. Simple numerica. methods a.e considered for the computa.ion of numerica. a.proxima.ions to the solution of the nonlinea. IBVPs. Using the discrete energy method we study the sta.ility a.d convergence of the numerica. a.proxima.ions. Numerica. experiments a.e ca.ried out to illustra.e our theoretica. results.

关键词： Dela. diffusion rea.tion equa.ion Energy method Sta.ility Convergence.