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The nature of the companion of PSR j.719-1438: a white dwarf or an exotic obj.ct?

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Research in Astronomy and Astrophysics 2012年第7期12卷 813-816页

作者： j. E. Horvath Instituto de Astronomia Geofísica e Ciências Atmosfricas - Universidade de So Paulo

We raise the possibility that the very dense, compact companion of PSR j.719-1438, which has a j.piter-like mass, is an exotic quark obj.ct rather than a light helium or carbon white dwarf. The exotic hypothesis naturally explains some of the observed features, and provides quite strong predictions for this system, to be confirmed or refuted in feasible future studies.

关键词： binary pulsars -- exotic matter-- pulsars: individual (PSR j.719-1438)

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA j.mes L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain inj.ry(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

Formation of High-quality Advanced High-k Oxide Layers at Low Temperature by Excimer UV Lamp-assisted Photo-CVD and Sol-gel Processing

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Chemical Research in Chinese Universities 2004年第4期20卷 396-402页

作者： YU j. j. Electronic & Electrical Engineering University College London

We have successfully demonstrated that high quality and high dielectric constant layers can be fabricated by low temperature photo-induced or -assisted processing. Ta_2O_5 and ZrO_2 have been deposited at t<400 ℃ by means of a UV photo-CVD technique and HfO_2 by photo-assisted sol-gel processing with the aid of excimer lamps. The UV annealing of as-grown layers was found to significantly improve their electrical properties. Low leakage current densities on the order of 10 -8 A/cm 2 at 1 MV/cm for deposited ultrathin Ta_2O_5 films and ca.10 -6 A/cm 2 for the photo-CVD ZrO_2 layers and photo-irradiated sol-gel HfO_2 layers have been readily achieved. The improvement in the leakage properties of these layers is attributed to the UV-generated active oxygen species O( 1D) which strongly oxidize any suboxides to form more stoichiometric oxides on removing certain defects, oxygen vacancies and impurities present in the as-prepared layers. The photo-CVD Ta_2O_5 films deposited across 10.16-cm Si wafers exhibit a high thickness uniformity with a variation of less than \{±2.0%\} being obtained for ultrathin ca.10 nm thick films. The lamp technology can in principle be extended to larger area wafers, providing a promising low temperature route to the fabrication of a range of high quality thin films for future ULSI technology.

关键词： Excimer lamp High-kdielectrics Thin film Chemical vapour deposition(CVD) Sol-gel processing

Temporal dynamics of neonatal hypoxic-ischemic encephalopathy inj.ries on magnetic resonance imaging

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Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.Gunn Laura Bennet Hamid Abbasi Mātai Medical Research Institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical Imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering Institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy inj.ries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain inj.ry may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

j.ffery-Hamel flow of non-Newtonian fluid with nonlinear viscosity and wall friction

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Applied Mathematics and Mechanics(English Edition) 2017年第6期38卷 815-830页

作者： j. NAGLER Department of Fluid Mechanics and Heat Transfer Faculty of Engineering Tel-Aviv University Ramat-Aviv 69978 Israel

A j.ffery-Hamel （j.H） flow model of the non-Newtonian fluid type inside a convergent wedge （inclined walls） with a wall friction is derived by a nonlinear ordinary differential equation with appropriate boundary conditions based on similarity relationships. Unlike the usual power law model, this paper develops nonlinear viscosity based only on a tangential coordinate function due to the radial geometry shape. Two kinds of solutions are developed, i.e., analytical and semi-analytical （numerical） solutions with suitable assumptions. As a result of the parametric examination, it has been found that the Newtonian normalized velocity gradually decreases with the tangential direction progress. Also, an increase in the friction coefficient leads to a decrease in the normalized Newtonian velocity profile values. However, an increase in the Reynolds number causes an increase in the normalized velocity function values. Additionally, for the small values of wedge semi-angle, the present solutions are in good agreement with the previous results in the literature.

关键词： j.ffery-Hamel (j.H) flow slip condition non-Newtonian fluid friction,nonlinear viscosity analytical solution numerical solution approximate solution

Segmentations of foreland belts and their tectonic mechanism in the Southwest Tarim Basin

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Science China Earth Sciences 2005年第10期48卷 1585-1598页

作者： j. Canerot j. Deramond Lab. de Bassin Dynamique Sedimentaire Universite Paul Sabatier Toulouse III 39 Allee Jules-Guesde 31062 Toulouse FranceLab. de Bassin Dynamique Sedimentaire Universite Paul Sabatier Toulouse III 39 Allee Jules-Guesde 31062 Toulouse France

Based on lots of field investigations and comprehensive interpretations of seismic profiles with outcrop cross-sections, this paper shows that the foreland belts surrounding the Southwest Tarim Foreland Basin have the regularity of segmentation along the strike of foreland belts. There are many thin-skinned thrusting systems thrusting from mountains to the basin and the arcuate back-thrusting systems to the mountains distributed at intervals in the front of West Kunlun-Pamir and Southern Tianshan. Between thrusting and back-thrusting systems, the strike-slip faults developed. The northeast uplifts and depressions of Southwest Tarim Basin correspond with the segmentation of foreland basin. The thin-skinned thrusting system is formed in the case that the thickness of sedimentary covers is less than 10 km in depth where the basement is an uplift belt in general. The back-thrusting systems and triangle zones are formed in the case that the thickness of sedimentary covers is larger than 8 km in depth where the basement is a depression zone. The main mechanics of segmentation of foreland basin are the difference of mountain uplift and deformation rate along the longitude of the mountains, the huge sedimentary rocks in different depression centers, the uplift belts and depression zones in the basement rocks, and multi-displaced weak layers in the foreland basin. The segmentation of Southwest Tarim Foreland Basin is due to the intra-plate deformation of re-orogenies of West Kunlun-Pamir and Southwest Tianshan and the co-related deformation between mountains and basement of basin since Neocene.

关键词： Southwest Tarim Basin, foreland basin,West Kunlun-Pamir and Tianshan, tectonic segmentation,structure of basement.

Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations

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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon j.Brown Rafael j.Yáñez-Muñoz Heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

A structural topological optimization method for multi-displacement constraints and any initial topology configuration

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Acta Mechanica Sinica 2010年第5期26卷 735-744页

作者： j. H. Rong j. H. Yi School of Automotive and Mechanical Engineering Changsha University of Science and TechnologyChangsha 410076 China

In density-based topological design, one expects that the final result consists of elements either black （solid material） or white （void）, without any grey areas. Moreover, one also expects that the optimal topology can be obtained by starting from any initial topology configuration. An improved structural topological optimization method for multidisplacement constraints is proposed in this paper. In the proposed method, the whole optimization process is divided into two optimization adj.stment phases and a phase transferring step. Firstly, an optimization model is built to deal with the varied displacement limits, design space adj.stments, and reasonable relations between the element stiffness matrix and mass and its element topology variable. Secondly, a procedure is proposed to solve the optimization problem formulated in the first optimization adj.stment phase, by starting with a small design space and advancing to a larger deign space. The design space adj.stments are automatic when the design domain needs expansions, in which the convergence of the proposed method will not be affected. The final topology obtained by the proposed procedure in the first optimization phase, can approach to the vicinity of the optimum topology. Then, a heuristic algorithm is given to improve the efficiency and make the designed structural topology black/white in both the phase transferring step and the second optimization adj.stment phase. And the optimum topology can finally be obtained by the second phase optimization adj.stments. Two examples are presented to show that the topologies obtained by the proposed method are of very good 0/1 design distribution property, and the computational efficiency is enhanced by reducing the element number of the design structural finite model during two optimization adj.stment phases. And the examples also show that this method is robust and practicable.

关键词： Topological optimization Displacement constraint Continuum structure Design space adj.stment Rational approximation material model

Unimodal Sequences of Gorenstein Ideals of Codimension 4

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Acta Mathematica Sinica,English Series 1998年第4期14卷 563-568页

作者： Hyoung j. Ko Department of Mathematics. Yonsei University 134 Shinchon-dong Seodaemun-gu. Seoul Korea 120-749

We present Gorenstein ideals of condimension 4 which have unimodal Hilbert functions.

关键词： k-configuration Hilbert function Minimal free resolution Gorenstein ideal of codimension 4