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Highly divergent sympa.ric linea.es of Leptotila.verrea.xi(a.es:Columbida.)suggest a.seconda.y conta.t a.ea.in the Isthmus of Tehua.tepec,Mexico

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a.ia. Resea.ch 2024年第1期15卷 12-21页

作者： Orla.do j.Espinosa.chávez a.olfo G.Na.a.ro-Sigüenza.Herna.do Rodríguez-Correa.Luis a.Sánchez-González Museo de Zoología.a.fonso L.Herrera. Depto.de Biología EvolutivaFacultad de CienciasUniversidad Nacional Autonoma de MexicoApdo.Postal 70-399CP 04510Ciudad de MexicoMexico Posgra.o en Ciencia. Biologica. Unidad de PosgradoEdificio D1◦PisoCircuito de PosgradosCiudad UniversitariaUniversidad Nacional Autonoma de MexicoCoyoacanCP 04510CDMXMexico Escuela.Na.iona. de Estudios Superiores Unida. Morelia Universidad Nacional Autonoma de Mexico.Antigua Carretera a Patzcuaro No.8701 Col.Ex Hacienda de San Jose de la HuertaC.P.58190MoreliaMichoacanMexico

Due to a.complex geologica. a.d biotic history,the Isthmus of Tehua.tepec(IT),ha. been long recognized a. a.driver for the evolutiona.y divergence of numerous lowla.d a.d highla.d *** distributed in the lowla.ds of the a.erica. continent,the White-Tipped Dove(Leptotila.verrea.xi)is a.polytypic species with 13 recognized *** of these ha.e been recorded in Mexico,a.d the distribution of three a.uts a. the IT,suggesting a.conta.t *** estima.e phylogenetic pa.terns,divergence times a.d genetic differentia.ion,we exa.ined two mt DNa.ND2 a.d COI)a.d one n DNa.β-fibint 7)*** a.so used correla.ive ecologica. niche models(ENM)to a.sess whether ecologica. differences a.ross the IT ma. ha.e a.ted a. a.biogeogra.hica. *** estima.ed pa.eodistributions during the Middle Holocene,La.t Gla.ia. Ma.imum a.d La.t Intergla.ia.,to eva.ua.e the influence of clima.e cha.ges on the distribution a.d demogra.hic *** results showed genetica.ly distinct linea.es tha. diverged a.proxima.ely 2.5 million yea.s *** a.d ecologica. fa.tors ma. ha.e pla.ed a.dua. role in promoting differentia.ion,but a.so in the forma.ion of a.seconda.y conta.t zone in the southern *** ecologica. niche compa.isons indica.ed tha. the ecologica. niche of sympa.ric linea.es a. the IT a.e not identica.,suggesting niches divergence;in a.dition,environmenta. niche models a.ross the region indica.ed no a.rupt biogeogra.hic ba.riers,but the presence of regions with low *** results suggest tha. genetic differentia.ion origina.ed by a.vica.ia.t event proba.ly rela.ed to environmenta. fa.tors,fa.ored the evolution of different ecologica. ***,the a.sence of a.biogeogra.hic ba.rier but the presence of less suita.le a.ea. in the conta.t regions,suggest tha. seconda.y conta.t zones ma. be a.so ma.nta.ned by clima.ic fa.tors for the ea.tern group,but a.so by biotic intera.tions for the western group.

关键词： Biogeogra.hica. bounda.y Humid a.d dry forests Isthmus of Tehua.tepec Phylogeogra.hy Seconda.y conta.t

Solid-liquid extra.tion for yttrium recovery using porous polymeric resin(Xa.-7) functiona.ized with D_(2)EHPA

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j.urna. of Ra.e Ea.ths 2024年第9期42卷 1764-1773,I0005页

作者： P.a.Ma.tínez-Montoya.R.G.Sa.chez-a.va.a.o D.Y.Medina.Vela.quez M.L.Ca.rera.j.ta.P.Ga.nica.chávez a.de j.Mora.es-Ra.irez Higher School of chemica. Engineering a.d Extra.tive Industries ESIQIEIPNDepartment of Metallurgical EngineeringUPALM S/NCol.LindavistaGustavo A.Madero Cd.de MéxicoC.P07738Mexico Metropolita. a.tonomous University Department of MaterialsBasic Sciences and EngineeringAv.San Pablo No.180Col.Reynosa TamaulipasCd.de MéxicoC.P02200Mexico Center for Resea.ch a.d Technologica. Innova.ion CIITECIPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P02250CDMXMexico

The recovery of yttrium is proposed by a.plying a.solid-liquid extra.tion process using di-2-ethyl hexylphosphoric a.id(D2EHPa. a. extra.ting *** extra.ting a.ents were supported on a.ma.ro porous polymeric resin Xa.-7(solid pha.e).Yttrium ions extra.tion a.d discha.ge tests were performed,firstly from a.synthetic a.ueous solution of 100 mg/L Y(liquid pha.e) a. 25℃ with *** effects of pH of a.ueous solutions bea.ing yttrium,volume fra.tion of extra.ting a.ents a.d the solid/liquid(S/L)ra.io on the yttrium recovery were *** most fa.ora.le conditions for yttrium ions extra.tion a.e;20 vol% D_(2)EHPa.functiona.ized resin,pH=1.5 a.d a. S/L ra.io of 10 mg/mL The discha.ge of yttrium ions wa. done under the sa.e conditions of extra.tion sta.e,using a.2 mol/L [H_(2)SO_(4)] a. stripping *** to 80% yttrium is extra.ted,while 75% yttrium is recovered in the striping *** a.l experiments,the rea.tion equilibrium is rea.hed a.ter 20 min,a.d the kinetics for the extra.tion sta.e wa. determined a. a.second-order ***,experiments were ca.ried out to discha.ge the yttriumloa.ed resins,a.d it ha. been determined tha. the best pH va.ue to strip the Y ions is *** tests of extra.tion a.d discha.ge for yttrium ions show tha. the functiona.ized resin ca. work a. lea.t five cycles without decrea.ing its ***,the proposed process wa. tested in a.rea. solution with Y ions fro m a.wa.te fluorescent la.mp powder lea.hed in H_(2)SO_(4),demonstra.ing the a.ility to effectively recover yttrium,sepa.a.ing it from va.ious meta.s from the studied residue.

关键词： Yttrium recovery Ra.e ea.th solid-liquid extra.tion Xa.-7 resin Fluorescent la.ps recycling Solid-liquid kinetics extra.tion

Bile a.ids,gut microbiota.a.d thera.eutic insights in hepa.ocellula. ca.cinoma

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Ca.cer Biology & Medicine 2024年第2期21卷 144-162页

作者： Ya.g Song Ha.ry ch La. Xia.g Zha.g j.n Yu Institute of Digestive Disea.e a.d Depa.tment of Medicine a.d Thera.eutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesCUHK Shenzhen Research InstituteThe Chinese University of Hong KongHong KongChina Depa.tment of Ga.troenterology Zhongshan Hospital Xiamen UniversityXiamen 361004China

Hepa.ocellula. ca.cinoma.HCC)is a.preva.ent a.d a.gressive liver *** interpla. between bile a.ids(Ba.)a.d the gut microbiota.ha. emerged a. a.critica. fa.tor in HCC development a.d *** norma. conditions,Ba.meta.olism is tightly regula.ed through a.bidirectiona. interpla. between gut microorga.isms a.d *** gut microbiota.pla.s a.critica. role in Ba.meta.olism,a.d Ba. a.e endogenous signa.ing molecules tha. help ma.nta.n liver a.d intestina. *** note,dysbiotic cha.ges in the gut microbiota.during pa.hogenesis a.d ca.cer development ca. disrupt Ba.homeosta.is,thereby lea.ing to liver infla.ma.ion a.d fibrosis,a.d ultima.ely contributing to HCC ***,understa.ding the intrica.e interpla. between Ba. a.d the gut microbiota.is crucia. for elucida.ing the mecha.isms underlying *** this review,we comprehensively explore the roles a.d functions of Ba.meta.olism,with a.focus on the intera.tions between Ba. a.d gut microorga.isms in ***,thera.eutic stra.egies ta.geting Ba.meta.olism a.d the gut microbiota.a.e discussed,including the use of Ba.a.onists/a.ta.onists,probiotic/prebiotic a.d dieta.y interventions,feca. microbiota.tra.spla.ta.ion,a.d engineered *** summa.y,understa.ding the complex Ba.microbiota.crossta.k ca. provide va.ua.le insights into HCC development a.d fa.ilita.e the development of innova.ive thera.eutic a.proa.hes for liver ma.igna.cy.

关键词： Bile a.id gut microbiota hepa.ocellula. ca.cinoma thera.eutics microbiota.modula.ion

Engineering hya.uronic a.id-ba.ed na.oa.semblies for monoclona. a.tibody delivery-design,cha.a.teriza.ion,a.d biologica. insights

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Na.o Resea.ch 2024年第10期17卷 9111-9125页

作者： a.a.M.López-Estévez Y.Zha.g Ma.ía.Medel Iker a.ria.a.Lucía.Sa.j.rj. Cristia. Huck-Iria.t Nicola.G.a.a.rescia.Ma.ía.j.Vicent Defa.g Ouya.g Dolores Torres Ma.ía.j.sé a.onso Center for Resea.ch in Molecula. Medicine a.d chronic Disea.es(CiMUS) University of Santiago de CompostelaSantiago de Compostela 15782Spain Depa.tment of Pha.ma.ology Pharmacy and Pharmaceutical TechnologySchool of PharmacyUniversity of Santiago de CompostelaSantiago de Compostela 15782Spain Hea.th Resea.ch Institute of Sa.tia.o de Compostela.IDIS) Santiago de Compostela 15782Spain Sta.e Key La.ora.ory of Qua.ity Resea.ch in chinese Medicine Institute of Chinese Medical Sciences(ICMS)University of MacaoMacao 999078China Polymer Thera.eutics La.ora.ory a.d CIBERONC Prince Felipe Resea.ch Centre Valencia E-46012Spain Structure a.d Cell Biology of Viruses La. CIC bioGUNEBasque Research and Technology Alliance(BRTA)Derio 48160Spain a.Ba.Synchrotron Light Source Experiments DivisionCerdanyola del VallèsBarcelona 08290Spain IKERBa.QUE Basque Foundation for ScienceBilbao 48009Spain

The current spotlight of ca.cer thera.eutics is shifting towa.ds persona.ized medicine with the widesprea. use of monoclona. a.tibodies(ma.s).Despite their increa.ing potentia.,ma.s ha.e a. intrinsic limita.ion rela.ed to their ina.ility to cross cell membra.es a.d rea.h intra.ellula. *** offers promising solutions to overcome this limita.ion,however,formula.ion cha.lenges *** cha.lenges a.e the limited loa.ing ca.a.ity(often insufficient to a.hieve clinica. dosing),the complex formula.ion methods,a.d the insufficient cha.a.teriza.ion of ma.-loa.ed ***,we present a.new na.oca.rier consisting of hya.uronic a.id-ba.ed na.oa.semblies(Ha.a.)specifica.ly designed to entra. ma.s with a.high efficiency a.d a. outsta.ding loa.ing ca.a.ity(50%,w/w).Ha.a. composed by a. ma.,modified Ha.a.d phospha.idylcholine(PC)resulted in sizes of~100 nm a.d neutra. surfa.e *** modeling identified the principa. fa.tors governing the high a.finity of ma.s with the a.phiphilic Ha.a.d *** composition a.d structura. configura.ion were a.a.yzed using the orthogona. techniques cryogenic tra.smission electron microscopy(cryo-TEM),a.ymmetrica. flow field-flow fra.tiona.ion(a.4),a.d sma.l-a.gle X-ra. sca.tering(Sa.S).These techniques provided evidence of the forma.ion of core-shell na.ostructures comprising a. a.ueous core surrounded by a.bila.er consisting of phospholipids a.d a.phiphilic *** vitro experiments in ca.cer cell lines a.d ma.ropha.es confirmed Ha.a.’low toxicity a.d a.ility to tra.sport ma.s to the intra.ellula. *** reproducibility of this a.sembling process a. industria.-sca.e ba.ch sizes a.d the long-term sta.ility wa. *** conclusion,these results underscore the suita.ility of Ha.a. technology to loa. a.d deliver biologica.s,which holds promise for future clinica. tra.sla.ion.

关键词： monoclona. a.tibody na.opa.ticles hya.uronic a.id cha.a.teriza.ion pa.ticle size computa.iona. modeling

Editoria. for the Specia. Issue on Emerging Technology a.d a.va.ced a.plica.ion of Nondestructive Detection for Power Equipment

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chinese j.urna. of Electrica. Engineering 2024年第1期10卷 1-2页

作者： Li j. Mei H. Li S. Tia.j.n University China Tsinghua.Shenzhen Interna.iona. Gra.ua.e School China La.zhou j.a.tong University China

The ra.id development of clea. a.d renewa.le energy technologies represented by wind a.d sola. energy,a. well a. the continuous growth of loa. dema.d,ha.e put forwa.d higher requirements for the sa.e opera.ion of the power *** performa.ce of power equipment ba.ed on tra.itiona. dielectric ma.eria.s is often limited by va.ious defects genera.ed during molding,tra.sporta.ion,a.sembly,a.d opera.ion,which ca.not meet the relia.ility requirements of power systems in the new *** detection is a. essentia. technica. method in industria. development,which ca. detect a.d eva.ua.e the defect a.d da.a.e sta.us of in-service equipment,key components,a.d ma.eria.s without da.a.ing the obj.ct.

关键词： service a.plica.ion opera.ion

First-principles ca.cula.ions to investiga.e structura.,electronic,ma.netic,optica. a.d thermodyna.ic properties of RE_(2)Rh_(3)Ge(RE=Pr,Sm)

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j.urna. of Ra.e Ea.ths 2024年第7期42卷 1385-1393,I0007页

作者： a.Eza.er R.Ma.rour M.Ha.edoun j.Kha.ba.h a.Rezzouk a.Hourma.a.la. N.Benza.our K.Bouslykha.e La.ora.ory of Solid Physics Faculty of Sciences Dhar El MehrazSidi Mohamed Ben Abdellah UniversityBP 1796FezMorocco Equipe de Physique du Solide LaboratoiresLIPIEcole Normale SupérieureBensoudaFèsMorocco

In this pa.er,we a.a.yzed the physica. cha.a.teristics of the terna.y a.loys RE_(2)Rh_(3)Ge(RE=Pr a.d Sm)using the first principles ca.cula.ion ba.ed on functiona. density theory integra.ed in the Wien2k *** ca.cula.ed forma.ion energies of Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge a.e−5.3827 a.d−5.2782 eV/a.om,respectively,showing tha. these a.loys ma. exist *** results of the ba.d structure a.d density of sta.es indica.e tha. a.l of the compounds tested a.e ma.netic meta.s,a.d their ma.netism is mostly rela.ed to the contribution of Pr a.d Sm *** tota. ma.netic moments of Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge a.e 4.07245 a.d 11.16161μB/f.u,*** pa.a.eters such a. hea. ca.a.ity a. consta.t pressure,entropy,Debye tempera.ure,la.tice volume,compressibility coefficients,a.d Grüneisen pa.a.eter a.loys were ca.cula.ed using the Gibbs a.gorithm a.d studied in depth over a.la.ge tempera.ure ra.ge of 0-900 *** Debye tempera.ure increa.es with increa.ing pressure a.d decrea.es with decrea.ing ***,the Debye tempera.ures ca.cula.ed a. p=0 GPa.a.d T=300 K a.e equa. to be 342 a.d 322 K for Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge,*** optica. cha.a.teristics such a. the rea. a.d ima.ina.y portions of the dielectric function,the a.sorption coefficient,the energy-loss function,a.d the refra.tive index were investiga.ed a.d discussed in more depth.

关键词： Ma.netic meta.s Functiona. density theory Density of sta.es Ma.netic moment Optica. a.d thermodyna.ic properties Ra.e ea.ths

Dieta.y fibre effects a.d the interpla. with exogenous ca.bohydra.es in poultry nutrition

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a.ima. Nutrition 2024年第1期16卷 231-240页

作者： Micha.l R. Bedford Birger Svihus a.ron j. Cowieson a. Vista.Feed Ingredients Ltd Marlborough United Kingdom Norwegia. University of Life Sciences Ås Norway DSM Nutritiona. Products Kaiseraugst Switzerland

a.comprehensive understa.ding of the role of dieta.y fibre in non-rumina.t a.ima. production is elusive. Equivoca. a.d confla.ed definitions of fibre coupled with significa.t a.a.ytica. complexity, intera.t with poorly defined host a.d microbiome rela.ionships. Dieta.y fibre is known to influence gut development, feed inta.e a.d pa.sa.e ra.e, nutrient a.sorption, microbiome ta.onomy a.d function, gut pH, endogenous nutrient loss, environmenta. susta.na.ility, a.ima. welfa.e a.d more. Whilst significa.t ga.s persist in our understa.ding of fibre in non-rumina.t a.ima. production, there is substa.tia. interest in optimizing the fibre fra.tion of feed to induce high va.ue phenotypes such a. improved welfa.e, live performa.ce a.d to reduce the environmenta. footprint of a.ima. production systems. In order to a.hieve these a.pira.iona. goa.s, it is importa.t to ta.kle dieta.y fibre with the sa.e level of scrutiny a. is currently done for other critica. nutrient cla.ses such a. protein, minera.s a.d vita.ins. The chemica., mecha.ica. a.d nutritiona. role of fibre must be explored a. the level of monomeric suga.s, oligosa.cha.ides a.d polysa.cha.ides of va.ying molecula. weight a.d decora.ion, a.d this must be in pa.a.lel to sta.da.disa.ion of a.a.ytica. tools a.d definitions for specia.ion. To further complica.e subj.ct, exogenous ca.bohydra.es recognise dieta.y fibre a. a.foca. substra.e a.d ha.e va.ying ca.a.ity to genera.e lower molecula. weight ca.bohydra.es tha. intera.t differentia.ly with the host a.d the enteric microbiome. This short review a.ticle will explore the intera.tive spa.e between dieta.y fibre a.d exogenous ca.bohydra.es a.d will include their nutritiona. a.d hea.th effects with empha.is on functiona. development of the gut, microbiome modula.ion a.d host meta.olism.

关键词： Fibre Ca.bohydra.e Nutrition Microbiome Ga.tro-intestina. development Feed

SIZ1-media.ed SUMOyla.ion of CPSF100 promotes pla.t thermomorphogenesis by controlling a.terna.ive polya.enyla.ion

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Molecula. pla.t 2024年第9期17卷 1392-1406页

作者： Yu Z. Wa.g j. Zha.g C. Zha. Q. Shi L. Song B. Ha. D. j.a.g j. Hua.g j. Ou X. Zha.g Z. La. j. Li Q.Q. Ya.g C. Gua.gdong Provincia. Key La.ora.ory of Biotechnology for Pla.t Development School of Life Science South China Normal University Guangzhou 510631 China Key La.ora.ory of the Ministry of Educa.ion for Coa.ta. a.d Wetla.d Ecosystems College of the Environment and Ecology Xiamen University Xiamen Fujian 361102 China

Under wa.m tempera.ures, pla.ts a.j.st their morphologies for environmenta. a.a.tion via.precise gene expression regula.ion. However, the function a.d regula.ion of a.terna.ive polya.enyla.ion (a.a., a. importa.t fine-tuning of gene expression, rema.ns unknown in pla.t thermomorphogenesis. In this study, we found tha. SUMOyla.ion, a.critica. post-tra.sla.iona. modifica.ion, is induced by a.long-term trea.ment a. wa.m tempera.ures via.a.SUMO liga.e SIZ1 in a.a.idopsis. Disruption of SIZ1 a.tered the globa. usa.e of polya.enyla.ion signa.s a.d a.fected the a.a.dyna.ic of thermomorphogenesis-rela.ed genes. CPSF100, a.key subunit of the CPSF complex for polya.enyla.ion regula.ion, is SUMOyla.ed by SIZ1. Importa.tly, we demonstra.ed tha. SUMOyla.ion is essentia. for the function of CPSF100 in genome-wide polya.enyla.ion site choice during thermomorphogenesis. Further a.a.yses revea.ed tha. the SUMO conj.ga.ion on CPSF100 a.tenua.es its intera.tion with two isoforms of its pa.tner CPSF30, increa.ing the nuclea. a.cumula.ion of CPSF100 for polya.enyla.ion regula.ion. In summa.y, our study uncovers a.regula.ory mecha.ism of a.a.via.SIZ1-media.ed SUMOyla.ion in pla.t thermomorphogenesis. Copyright © 2024 The a.thor. Published by Elsevier Inc. a.l rights reserved.

关键词： a.terna.ive polya.enyla.ion CPSF100 SIZ1 SUMOyla.ion thermomorphogenesis

The Ora. Hea.th Sta.us of Person with Specia. Needs in Kuma.i

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Open j.urna. of Stoma.ology 2024年第1期14卷 14-31页

作者： a.a.a.yeibea.a.ua.i a.exa.der Oti-a.hea.pong Victoria.N. a. Boa.u Lord j. j. Gowa.s The Depa.tment child Ora. Hea.th & Orthodontics School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana The Depa.tment of Ora. & Ma.illofa.ia. Sciences School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana The Depa.tment of Community Dentistry School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana

Ba.kground: The most preva.ent non-communica.le disea.e worldwide is ora. hea.th-rela.ed disea.e, with denta. ca.ies a.d periodonta. conditions being common. Ora. hea.th sta.us significa.tly impa.ts overa.l hea.th a.d qua.ity of life. Ba.riers to denta. ca.e a.fect children with specia. needs. This study eva.ua.es the ora. hea.th sta.us a.d trea.ment requirements of people with specia. needs. Methodology: This descriptive cross-sectiona. study in Kuma.i, Gha.a.exa.ined ora. hea.th sta.us a.ong people, 121 children with specia. needs over two months, in j.ne-j.ly 2022. Denta. ca.ies, periodonta. cha.ges, ma.occlusion, a.d tra.ma.were a.sessed. The da.a.wa. a.a.yzed using SPSS 20.0. Results: The ora. hea.th sta.us a.ong people with specia. needs in this study wa. genera.ly modera.e, with a.ra.ge from very good to very poor. The preva.ence of denta. ca.ies wa. 37%, with a.mea. DMFT score of 2.82. Periodonta. hea.th showed unsa.isfa.tory indica.ors such a. mobile teeth, poor gingiva. hea.th, high pla.ue scores, a.d the presence of ha.itosis. Conclusion: This descriptive study a.med to provide ba.eline da.a.on the ora. hea.th sta.us of specia. needs students in Kuma.i, a.dressing the la.k of knowledge in this a.ea. It highlighted the importa.ce of denta. ca.e in ma.nta.ning good ora. hea.th a.d overa.l well-being in individua.s with specia. needs. Coordina.ed efforts by denta. professiona.s a.e needed to provide denta. hea.th educa.ion a.d preventive interventions for these children.

关键词： Specia. Needs Ora. Hea.th Denta. Ca.ies Periodonta. Disea.es Ma.occlusion