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World journal of Gastroenterology 2008年第13期14卷 1969-1971页

作者： A Mata j llach jM Bordas Digestive Endoscopy Unit Gastroenterology Service Imd Hospital Clinic Barcelona Barcelona 08036 Spain

Wireless capsule endoscopy is a new technique that allows complete exploration of the small bowel without exlemal wires. Its role has been analyzed in many small bowel diseases such as obscure gastrointestinal bleeding, Crohn＇s disease and gastrointestinal polyposis syndromes with promising results. Studies on other pathologies （i.e. small bowel tumour, celiac disease） are under evaluation to define the role of this technique.

关键词： Wireless capsule endoscopy Small bowel Obscure gastrointestinal bleeding Crohn's disease Gastrointestinal polyposis syndrome

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对遗传性胃肠道息肉综合征患者行小肠部位无线胶囊内镜和钡剂造影检查的一项前瞻性研究

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世界核心医学期刊文摘（胃肠病学分册） 2005年第9期1卷 33-34页

作者： Mata A. llach j. Castells A. 徐瑞 Digestive Endoscopy Unit Gastroenterology Department Hospital Clnic Villarroel 170 08036-Barcelona Catalonia Spain Dr.

Background: Capsule endoscopy has demonstrated its clinical utility in the evaluation of the small bowel, and, accordingly, it has been suggested that it could be useful for the identification of small-intestinal polyps in patients with polyposis syndromes. The objective was to establish the effectiveness of wireless capsule endoscopy for detecting small-bowel polyps in patients with hereditary GI polyposis syndromes in comparison with barium contrast series. Methods: Consecutive patients with GI polyposis syndromes were included. Small-bowel follow-through series and capsule endoscopy were performed within 1 week, in a blind fashion. The number and the location of polyps were analyzed. Results: Twenty-four patients with familial adenomatous polyposis (n = 20) or Peutz-jeghers syndrome (n = 4) were included. Capsule endoscopy detected small-bowel polyps in 7 of 24 patients (29%), whereas a barium contrast study identified small-intestinal polyps in only 3 of these 7 patients. In the 4 remaining patients, all of them with familial adenomatous polyposis, polyps detected by the capsule but missed in radiographic series were located at either ileum (2 patients), jejunum (1), or duodenum (1). No procedure-related complication was observed in any patient. Conclusions: Wireless capsule endoscopy is a highly accurate technique for the detection of small-bowel polyps in patients with hereditary GI polyposis syndromes, and it represents a valuable alternative to barium contrast series in the surveillance of patients with Peutz-jeghers syndrome.

关键词：钡剂造影胶囊内镜单盲法性腺瘤队列研究放射影像替代方法临床实用性

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