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journal of Environmental Sciences 2008年第7期20卷 878-884页

作者： M A Mottaleb j h zimmerman T W Moy Department of Chemistry and Biochemistry Baylor UniversityP.O.Box 97348WacoTX 76798USA. U.S.Environmental Protection Agency National Exposure Research LaboratoryEnvironmental Sciences Division944 East Harmon AveLas VegasNV 89119USA

Low levels (ng/g) of musk ketone (MK),used as a fragrance additive in the formulation of personal care products,are frequently detected in the water and other ***,aquatic organisms can be continuously exposed to *** this study,kinetics and dose-response assessments of 2-amino-MK (AMK) metabolite,bound to cysteine-hemoglobin (hb) in rainbow trout,formed by enzymatic nitro-reduction of MK have been *** were exposed to a single exposure of 0.010,0.030,0.10,and 0.30 mg MK/g ***...

关键词： biotransformation kinetics hemoglobin adducts dose-response nitro musks biomarker fish

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肝脏疾病时血清酶类的状况

生理科学进展 1960年第2期 176-188页

作者： M.West h.j.zimmerman 李增烈

目前已經設計出的肝功能检查已超过100种,但其中还沒有一种单独使用能可靠地鑑别肝細胞性黃疸与梗阻性黄疸,或区分肝脏与非肝脏疾病。要达到此目的,許多学者都着重指出:須要用数个实驗室測定肝功能状态的方法。新增加的診断肝脏疾病的... 详细信息

目前已經設計出的肝功能检查已超过100种,但其中还沒有一种单独使用能可靠地鑑别肝細胞性黃疸与梗阻性黄疸,或区分肝脏与非肝脏疾病。要达到此目的,許多学者都着重指出:須要用数个实驗室測定肝功能状态的方法。新增加的診断肝脏疾病的方法当然要引起我們的兴趣。近来对于轉氨酶与其它血清酶类的研究指出:在肝脏病人中这些酶有特征性的异常水平。在人与动物血清中已証明有許多种酶存在(表1),淀粉酶、脂酶、硷性与酸性磷酸酶及胆硷脂酶很久以来就被临床医师們所研究。过去的十

关键词：肝脏疾病酶类梗阻性黄疽 GOT 血清酶硷性磷酸酶

Trafficking of Vietnamese women and girls for marriage in China

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Global health Research and Policy 2017年第1期2卷 55-63页

作者： heidi Stöckl Ligia Kiss jobst Koehler Dung Thuy Dong Cathy zimmerman Gender Violence and health Centre Department of Global Health and DevelopmentFaculty of Public Health and PolicyLondon School of Hygiene and Tropical Medicine15-17 Tavistock PlaceLondon WC1H 9SEUK IOM Vietnam Ho Chi MinhVietnam

Background:Bride-trafficking has been a growing phenomenon in Southeast Asia,particularly in China,where one-child policies have resulted in demographic imbalances favoring ***,empirical evidence about women and girls sold into marriage in China remains ***:This study describes the experiences of 51 Vietnamese women and girls as young as 14 in post-trafficking services who were sold into marriage in China.A consecutive sample of individuals from five services in Vietnam were invited to be interviewed within the first 2 weeks of *** is part of a wider dataset for research on the health of men,women,and children in post-trafficking services in Cambodia,Thailand,and Vietnam,the largest study to date on human trafficking and *** calculated proportions for all variables and conducted bivariate analyses using Fisher Exact Tests for their associations with mental health disorders ***:Before leaving home,31%(n=15)participants were *** reported high levels of sexual violence(n=43;86%)while trafficked and59%(n=30)spent time in detention before returning to *** in post-trafficking care 52.9%(n=27)reported probable depression,anxiety or post-traumatic stress disorders(PTSD),two women(4%)attempted suicide in the past month and 38(75%)remained afraid of their ***(22%)became pregnant while trafficked,and seven(16%)were pregnant at the ***:The cross-border bride trade between Vietnam and China raises complex policy issues,including questions about detention and immigration rights and strategies for supported return processes,including maternal and child health *** the repercussions of China’s absent female population will persist,Vietnam and China must grapple with the political and social conditions to implement prevention strategies,and resources for women who fall prey to this cross-border bride trade.

关键词： human trafficking Vietnam China Forced marriage Mental health and violence against women

Donor preoperative oxygen delivery and post-extubation hypoxia impact donation after circulatory death hypoxic cholangiopathy

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World journal of Gastroenterology 2016年第12期22卷 3392-3403页

作者： Thomas j Chirichella C Michael Dunham Michael A zimmerman Elise M Phelan M Susan Mandell Kendra D Conzen Stephen E Kelley Trevor L Nydam Thomas E Bak Igal Kam Michael E Wachs Department of Surgery Division of Transplant Surgery University of Colorado Aurora CO 80045 United States Trauma/Critical Care Services St. Elizabeth Health Center Youngstown OH 44501 United States Department of Transplant Surgery Medical College of Wisconsin Milwaukee WI 53226 United States Department of Anesthesiology University of Colorado Aurora CO 80045 United States Donor Alliance Organ Procurement Organization Denver CO 80045 United States Department of Transplant Surgery Children's Hospital Colorado Aurora CO 80045 United States

AIM: To evaluate donation after circulatory death (DCD) orthotopic liver transplant outcomes [hypoxic cholangiopathy (hC) and patient/graft survival] and donor ***: From 2003-2013, 45 DCD donor transplants were performed. Predonation physiologic data from UNOS DonorNet included preoperative systolic and diastolic blood pressure, heart rate, ph, SpO2, PaO2, FiO2, and hemoglobin. Mean arterial blood pressure was computed from the systolic and diastolic blood pressures. Donor preoperative arterial O2 content was computed as [hemoglobin (gm/dL) × 1.37 (mL O2/gm) × SpO2%) + (0.003 × PaO2)]. The amount of preoperative donor red blood cell transfusions given and vasopressor use during the intensive care unit stay were documented. Donors who were transfused ≥ 1 unit of red-cells or received ≥ 2 vasopressors in the preoperative period were categorized as the red-cell/multi-pressor group. Following withdrawal of life support, donor ischemia time was computed as the number-of-minutes from onset of diastolic blood pressure hg until aortic cross clamping. Donor hypoxemia time was the number-of-minutes from onset of pulse oximetry hypoxia score was (ischemia time + hypoxemia time) ÷ donor preoperative ***: The 1, 3, and 5 year graft and patient survival rates were 83%, 77%, 60%; and 92%, 84%, and 72%, respectively. hC occurred in 49% with 16% requiring retransplant. hC occurred in donors with increased age (33.0 ± 10.6 years vs 25.6 ± 8.4 years, P = 0.014), less preoperative multiple vasopressors or red-cell transfusion (9.5% vs 54.6%, P = 0.002), lower preoperative hemoglobin (10.7 ± 2.2 gm/dL vs 12.3 ± 2.1 gm/dL, P = 0.017), lower preoperative arterial oxygen content (14.8 ± 2.8 mL O2/100 mL blood vs 16.8 ± 3.3 m

关键词： Orthotopic liver transplantation Ischemic cholangiopathy hypoxic cholangiopathy Donation after circulatory death Biliary complications Reperfusion injury

Enhanced Mass Transfer in Microbubble Driven Airlift Bioreactor for Microalgal Culture

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Engineering（科研） 2013年第9期5卷 735-743页

作者： Kezhen Ying Mahmood K. h. Al-Mashhadani james O. hanotu Daniel j. Gilmour William B. zimmerman Department of Chemical and Biological Engineering University of Sheffield Sheffield UK Department of Molecular Biology and Biotechnology University of Sheffield Sheffield UK

In this study, the effect of microfluidic microbubbles on overall gas-liquid mass transfer (CO2 dissolution and O2 removal) was investigated under five different flow rates. The effect of different liquid substrate on CO2 mass transfer properties was also tested. The results showed that the KLa can be enhanced by either increasing the dosing flowrate or reducing the bubble size;however, increasing the flow rate to achieve a higher KLa would ultimately lower the CO2 capture efficiency. In order to achieve both higher CO2 mass transfer rate and capture efficiency, reducing bubble size (e.g. using microbubbles) has been proved more promising than increasing flow rate. Microbubble dosing with 5% CO2 gas showed improved KLa by 30% -?100% across different flow rates, compared to fine-bubble dosing. In the real algal culture medium, there appears to be two distinct stages in terms of KLa, divided by the ph of 8.4.

关键词： Microbubbles KLa CO2 Capture Algal Culture

Occupational,physical,sexual and mental health and violence among migrant and trafficked commercial fishers and seafarers from the Greater Mekong Subregion(GMS):systematic review

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Global health Research and Policy 2018年第1期3卷 89-101页

作者： Nicola S.Pocock Long hoang Nguyen Don Eliseo Lucero-Prisno III Cathy zimmerman SiânOram Department of Global health and Development Faculty of Public Health and Policy15-17 Tavistock PlaceLondon WC1H 9SHUK United Nations University International Institute of Global health UKM Medical CentreJalan Yaacob LatifBandar Tun Razak56000 CherasKuala LumpurMalaysia School of Medicine and Pharmacy Vietnam National UniversityNo.144 Xuan Thuy StreetCau Giay districtHanoiVietnam Department of Public health Emerging and Interdisciplinary Sciences Building(ES)South CampusXi′an Jiaotong-Liverpool University111 Ren′ai RoadSuzhou Dushu Lake Science and Education Innovation DistrictSuzhou Industrial ParkSuzhou 215123People’s Republic of China Section of Women’s Mental health Institute of PsychiatryPsychology and Neuroscience16 De Crespigny ParkKings College LondonLondon SE58AFUK

Background:Little is known about the health of GMS commercial fishers and seafarers,many of whom are migrants and some *** systematic review summarizes evidence on occupational,physical,sexual and mental health and violence among GMS commercial fishers/***:We searched 5 electronic databases and purposively searched grey *** or qualitative studies reporting prevalence or risk of relevant outcomes were *** reviewers independently screened *** were extracted on nationality and long/short-haul fishing where ***:We identified 33 eligible papers from 27 *** fishers/seafarers were included in n=12/13 grey literature and n=1/20 peer-reviewed *** peer-reviewed papers:11 focused on hIV/AIDS/sexual health;nine on occupational/physical health;one study included mental health of trafficked *** was quantitatively measured in eight papers with prevalence of:11-26%in port convenience samples;68-100%in post-trafficking service *** fishers/seafarers whether trafficked or not worked extremely long hours;trafficked long-haul fishers had very limited access to care following injuries or ***-known risks reported among fishers included penile oil injections and *** found just one work safety intervention study and inconclusive evidence for differences in the outcomes by *** are limited by methodological weaknesses of primary ***:Results show an absence of high-quality epidemiological studies beyond sexual *** and pilot intervention research on occupational,physical and mental health among GMS commercial fishers and seafarers is *** studies should include questions about violence and *** and reporting standards of grey literature should be improved.

关键词： Migrant fishermen human trafficking Seafarers Migrant workers

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组培繁殖方法在木本植物中的应用(续)

林业科技通讯 1986年第12期 29-30+28页

作者： Richard h.zimmerman ,成小飞

木本植物组织培养所面临的问题Navatel将大规模应用组织培养生产所面临的问题分为两类:经济问题和技术问题。经济问题劳动成本:进一步地利用离体繁殖最大的阻碍是所需劳动量极大,无论是木本植物还是草本植物,劳动成本都占组培繁殖总成本... 详细信息

木本植物组织培养所面临的问题Navatel将大规模应用组织培养生产所面临的问题分为两类:经济问题和技术问题。经济问题劳动成本:进一步地利用离体繁殖最大的阻碍是所需劳动量极大,无论是木本植物还是草本植物,劳动成本都占组培繁殖总成本的60—80%。因此,必需降低繁殖植株各阶段的劳动消耗量。

关键词：木本植物组培繁殖

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组培繁殖方法在木本植物中的应用

林业科技通讯 1986年第11期 32-33+5页

作者： Richard h.zimmerman ,成小飞

在过去十年中,木本植物组培的商业性生产,已由一种可能性发展成迅速普及的现实。无论从生产的数量,还是从繁殖的种和品种数来看,这种变化确实具有重大的意义。关于这方面的进展,在大量的科技文献或科普文献中都有详细的报道,然而也有许... 详细信息

在过去十年中,木本植物组培的商业性生产,已由一种可能性发展成迅速普及的现实。无论从生产的数量,还是从繁殖的种和品种数来看,这种变化确实具有重大的意义。关于这方面的进展,在大量的科技文献或科普文献中都有详细的报道,然而也有许多要从其它途径才能得到。若以头两次专题讨论会会议文集所报道的

关键词：组培繁殖苹果砧木木本植物

巴尔兹维尔果树实验室和北美果树植物的显微繁殖

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国外农学(果树) 1983年第2期 19-22页

作者： zimmerman R.h. 黄贞光

在美国,有关组织培养研究没有形成中心,而是由某些机构的若干小组从事这项研究。这些机构包括大学、政府机构和私人实验室。公办和私立大学都设有实验室从事于植物组织培养的研究。另外,在每个州的农业大学的附属农业试验站,有大批科学... 详细信息

在美国,有关组织培养研究没有形成中心,而是由某些机构的若干小组从事这项研究。这些机构包括大学、政府机构和私人实验室。公办和私立大学都设有实验室从事于植物组织培养的研究。另外,在每个州的农业大学的附属农业试验站,有大批科学家从事于植物组织培养方面的基础研究和应用研究。像美国农业部这类政府机构,不但有自己的实验室开展此项研究,而且也资助农业试验站和大学的有关研究。此外,一些私人机构和公司,例如帕勃化学研究所和卫尔赫塞公司也积极制订有关的研究计划,从事于某一特殊作物或品种的研究。

关键词：果树弥雾巴尔兹农药施用创伤组织愈伤组织植物组培植物组织培养继代培养繁殖系数不定芽实验室株系琼脂培养基增殖培养基农业试验站营养液液体培养基维尔

Comparison of Renal hemodynamic Effect of Ramiprilat to Captopril: Possible Role of Kinins

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中华高血压杂志(中英文) 1994年第2期 108-113页

作者： Ke Chen zimmerman BG(Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455 )

The purpose of this study was to compare the angiotensin converting enzyme (ACE ) inhibitor ramiprilat to captopril with respect to its efficacy in decreasing blood pressure (BP) and increasing renal blood flow (RBF),when administered intravenously (i. v. ),or as in a separate group of experiments when given intrarenally (i. a ). Thirty-four anesthetized rabbits were employed in 3 groups of experiments in which BP and RBF were the measured parameters. In Group I,ramiprilat (1 mg/kg and 0. 5 mg/kg· h-1 i. v. )decreased BP from 107 ± 5 to 83± 8 mmhg and increased RBF from 33± 3 ml/min to 44± 7 ml/min. Captopril (2 mg/kg and 1 mg/kg· h-1 i. v. ) decreased BP from 99 ± 6 to 77 ± 8 mmhg and increased RBF from 30±1 to 42± 3 ml/min. Both ramiprilat and captopril abolished the pressor effect and greatly attenuated the renal vasoconstrictor response to injected angiotensin I. When the ACE inhibitors were administered in graded doses i. a. (Group Ⅱ ), they caused a similar increase in RBF , but a lesser decrease in BP compared to those when given i. v. Ramiprilat was more potent than captopril by either route of administration. In the presence of hK2 kinin receptor blockade by hOE 140 (Group Ⅲ ), the effect of ramiprilat and captopril on BP and RBF did not differ from that in Group Ⅱ. In conclusion, ramiprilat and captopril cause a similar renal hemodynamic effect and decrease in BP,and there is no difference in their efficacy either in the presence or absence of BK antagonism.

关键词： angiotensin converting enzyme captopril renal blood flow