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Artificial intelligence for characterization of diminutive colorectal polyps:A feasibility study comparing two computer-aided diagnosis systems

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Artificial Intelligence in Gastrointestinal Endoscopy 2024年第1期5卷 11-22页

作者： Quirine Eunice Wennie van der Zander ramon M Schreuder Ayla Thijssen Carolus H j Kusters nikoo Dehghani Thom Scheeve Bjorn Winkens Mirjam C M van der Ende-van Loon Peter H n de With Fons van der Sommen Ad A M Masclee Erik j Schoon Department of Gastroenterology and Hepatology Maastricht University Medical CenterMaastricht 6202 AZNetherlands GrOW School for Oncology and ReproductionMaastricht UniversityMaastricht 6200 MDNetherlands Division of Gastroenterology and Hepatology Catharina Hospital EindhovenEindhoven 5602 ZANetherlands Department of Electrical Engineering Eindhoven University of TechnologyEindhoven 5600 MBNetherlands Department of Methodology and Statistics Maastricht UniversityPostbus 6166200 MD MaastrichtNetherlands School for Public Health and Primary Care Maastricht UniversityMaastricht 6200 MDNetherlands

BACKGrOUnD Artificial intelligence(AI)has potential in the optical diagnosis of colorectal *** To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for Colorectal Polyps(AI4CrP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,japan).CADx influence on the optical diagnosis of an expert endoscopist was also *** AI4CrP was developed in-house and CAD EYE was proprietary software provided by *** CADxsystems exploit convolutional neural *** polyps were characterized as benign or premalignant and histopathology was used as gold ***4CrP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with valuesndicating benign and values≥0.6 indicating premalignant colorectal *** confidence characterizations were defined as values 40%around the cut-off value of 0.6(nd>0.76).Self-critical AI4CrP’s diagnostic performances excluded low confidence *** AI4CrP use was feasible and performed on 30 patients with 51 colorectal ***-critical AI4CrP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to *** EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%*** performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CrP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed *** real-time use of AI4CrP was *** confidence values provided by a CADx is novel and self-critical AI4CrP sho

关键词： Artificial intelligence Colorectal polyp characterization Computer aided diagnosis Diminutive colorectal polyps Optical diagnosis Self-critical artificial intelligence

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美国对领海以外水下文化遗产的保护：问题和前景

水下考古

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水下考古 2024年第00期 183-199页

作者：里卡多·j·埃里亚付琴雯波士顿大学考古系美国考古学会湖北警官学院

本文根据海洋法原则和联合国教科文组织《保护水下文化遗产公约》草案，分析美国目前对领海以外水下文化遗产的处置方式。

关键词：水下文化遗产文物打捞

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neuroprotective therapy for retinal neurodegenerative diseases by stem cell secretome

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neural regeneration research 2021年第1期16卷 117-118页

作者： ricardo Usategui-Martín Ivan Fernandez-Bueno Instituto Universitario de Oftalmobiología Aplicada(IOBA) Retina GroupUniversidad de ValladolidValladolidSpain Centro en red de Medicina regenerativa y Terapia Celular de Castilla y León Red Temática de Investigación Cooperativa en SaludOftaredInstituto de Salud Carlos IIIValladolidSpain

retinal neurodegenerative diseases like agerelated macular degeneration,glaucoma,diabetic retinopathy or retinitis pigmentosa are the most frequent causes of incurable low vision and blindness *** had been estimated that the prevalence of these diseases varies between 1/750 and 1/5000 depending on the region,the level of consanguinity or ethnicity(na et al.,2017).The functional and structural complexity of the retina makes it susceptible to multiple types of pathogenic damage.

关键词： diseases protective degenerative

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Are we ready for telemonitoring inflammatory bowel disease?A review of advances,enablers,and barriers

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World journal of Gastroenterology 2023年第7期29卷 1139-1156页

作者： javier Del Hoyo Mónica Millán Alejandro Garrido-Marín Mariam Aguas Department of Gastroenterology La Fe University and Polytechnic HospitalValencia 46026Spain Department of Surgery La Fe University and Polytechnic HospitalValencia 46026Spain Health research Institute La Fe La Fe University and Polytechnic HospitalValencia 46026Spain

This review summarizes the evidence about telemonitoring in patients with inflammatory bowel disease(IBD). To give an overview of the advances performed, as well as the enablers and barriers which favoured/hindered telemonitoring implementation. We performed a literature search in Pub Med, EMBASE, MEDLInE, Cochrane Database, Web of Science and Conference Proceedings. Titles and abstracts published up to September 2022 were screened for a set of inclusion criteria: telemonitoring intervention, IBD as the main disease, and a primary study performed. ninety-seven reports were selected for full review. Finally, 20 were included for data extraction and critical appraisal. Most studies used telemonitoring combined with tele-education, and programs evolved from home telemanagement systems towards web portals through m Health applications. Web systems demonstrated patients’ acceptance, improvement in quality of life, disease activity and knowledge, with a good cost-effectiveness profile in the short-term. Initially, telemonitoring was almost restricted to ulcerative colitis, but new patient reported outcome measures, home-based tests and mobile devices favoured its expansion to different patients’ categories. However, technological and knowledge advances led to legal, ethical, economical and logistic issues. Standardization of remote healthcare is necessary, to improve the interoperability of systems as well as to address liability concerns and users’ preferences. Telemonitoring IBD is well accepted and improves clinical outcomes at a lower cost in the short-term. Funders, policymakers, providers, and patients need to align their interests to overcome the emerging barriers for its full implementation.

关键词： Inflammatory bowel disease Telemedicine Telemonitoring Information and communication technology Crohn´s disease Ulcerative colitis

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Predicting elastic properties of hard-coating alloys using ab-initio and machine learning methods

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npj Computational Materials 2022年第1期8卷 139-148页

作者： H.Levämäki F.Tasnádi D.G.Sangiovanni L.j.S.johnson r.Armiento I.A.Abrikosov Department of Physics Chemistry and BiologyLinköping UniversitySE-58183LinköpingSweden Sandvik Coromant S-12680StockholmSweden Materials Modeling and Development Laboratory National University of Science and Technology‘MISIS’119049MoscowRussia

Accelerated design of hard-coating materials requires state-of-the-art computational tools,which include data-driven techniques,building databases,and training machine learning *** develop a heavily automated high-throughput workflow to build a database of industrially relevant hard-coating materials,such as binary and ternary *** use the high-throughput toolkit to automate the density functional theory calculation *** present results,including elastic constants that are a key parameter determining mechanical properties of hard-coatings,for X_(1−x)Y_(x)n ternary nitrides,where X,Y∈{Al,Ti,Zr,Hf}and fraction x=0,1/4,1/2,3/4,*** also explore ways for machine learning to support and complement the designed *** find that the crystal graph convolutional neural network trained on ordered lattices has sufficient accuracy for the disordered nitrides,suggesting that existing databases provide important data for predicting mechanical properties of qualitatively different types of materials,in our case disordered hard-coating alloys.

关键词： coating alloys ternary

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“反介入”战役及制胜要素——《反介入战争》第三章(上)

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兵器 2024年第9期 50-57页

作者： [美]萨姆·j·坦格里迪吴志丹(译) 不详

概念并非都能成为战略。概念只是一种粗略分析,是对观念或现象的界定方法。关于“战略”的界定很多,但也许最简洁的是美国海军少将j·威利提出的:“战略是一种为了达成某些目标的行动计划;是一种意图以及为实现该意图的措施体系。”

关键词：威利措施体系界定方法粗略分析行动计划第三章战略介入

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Slope Instability on Pyroclastic Deposits: Landslide Distribution and risk Mapping in Zacapoaxtla, Sierra norte De Puebla, Mexico

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journal of Mountain Science 2006年第1期3卷 1-19页

作者： Borja-Baeza r.C. Esteban-Chávez O Marcos-López j. Pea-Garnica r.j. Alcántara-Ayala I. Institute of Geography UnAM Circuito Exterior C.U. Coyoacan 04510 Mexico D.F. Institute of Geography UNAM Circuito Exterior C.U. Coyoacan 04510 Mexico D.F.Institute of Geography UNAM Circuito Exterior C.U. Coyoacan 04510 Mexico D.F.Institute of Geography UNAM Circuito Exterior C.U. Coyoacan 04510 Mexico D.F.Institute of Geography UNAM Circuito Exterior C.U. Coyoacan 04510 Mexico D.F.

In October 1999, rainfall induced landslides devastated different communities of the Sierra norte, Puebla, causing more than 250 victims and economic losses greater than $ 450 million. The town of Zacapoaxtla was one of the sectors most affected by slope instability due to the existing geological features and geomorphic characters determined by material properties, landforms and processes. Extensive areas formed by pyroclastic piedmonts developed on the Quaternary volcanic ignimbrite deposits highly dissected by marginal gully erosion combined with an extreme rainfall event played a significant role as an ideal scenario for the occurrence of landsliding. Distribution of landslides triggered by rainfall within the main sector of the Zacapoaxtla municipality was analyzed by using IKOnOS images in terms of exploring the likely relationship between mass movement incidence and levels of vegetation density. The later was undertaken by means of producing an nDVI and applying a fragmentation algorithm. Finally, a map of potential areas of mass movements risk was produced based on the combination of a socio-economic vulnerability index, geologic and geomorphological maps and the spatial landslide distribution.

关键词： rainfall landslides IKOnOS vegetation density risk Mexico

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两场战争的故事--《反介入战争》第一章(上)

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兵器 2024年第4期 68-75页

作者： [美]萨姆·j.坦格里迪吴志丹(译) 不详

本书以两场战争的故事开头,一场发生在公元前480年,另一场发生在1991年。第一场战争开创了“反介入”战略运用的先河,并留有大量历史记录。第二场是运用“反介入”和“区域拒止”的现代战争,运用者通常以美国及其盟友作为可能的假想敌。

关键词：区域拒止战略运用假想敌历史记录现代战争故事介入

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Effect of induced shielding current transmission in longitudinal direction on levitation force of melt grown single-domain YBa_2Cu_3O_(7-x) cylindrical superconductor

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Science China(Physics,Mechanics & Astronomy) 2004年第2期47卷 146-153页

作者： r. nicolsky r. de Andrade jr LASUP-DEE UFRJ Ilha do Fundao Cx.P.68515 21945-970 Rio de Janeiro RJ Brasil Correspondence should be addressed to Yang Wanmin LASUP-DEE UFRJ Ilha do Fundao Cx.P.68515 21945-970 Rio de Janeiro RJ Brasil Correspondence should be addressed to Yang Wanmin

A novel layer deletion method is used to experimentally investigate the effect of induced shielding current transmission (ISCT) in the longitudinal direction on the levitation force of a single-domain YBa2Cu3O7?x (YBCO) cylindrical superconductor (?30×7 mm). In the experiment the sample was gradually sliced into two equal sheets, at the middle height along a diameter with 5 mm every step. The experimental results show that the levitation force is closely related with the ISCT in the longitudinal direction. Any layer deletion, even a small piece of layer deletion can reduce the levitation force of the sample. After the whole layer was deleted the levitation force can diminish about 50%. It is also found that the levitation force is directly proportional to the effective factor of surface area, which is equal to the top surface area divided by the total surface area parallel to the top surface of the sample.

关键词： melt growth, single domain YBCO, levitation force, induced current distribution.

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Linear and nonlinear torsional free vibration of functionally graded micro/nano-tubes based on modified couple stress theory

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Applied Mathematics and Mechanics(English Edition) 2016年第6期37卷 725-740页

作者： A.r.SETOODEH M.rEZAEI M.r.ZEnDEHDEL SHAHrI Faculty of Mechanical and Aerospace Engineering Shiraz University of Technology

The linear and nonlinear torsional free vibration analyses of functionMly graded micro/nuno-tubes （FGMTs） are analytically investigated based on the couple stress theory. The employed non-classical continuum theory contains one material length scale parameter, which can capture the small scale effect. The FGMT model accounts for the through-radius power-law variation of a two-constituent material. Hamilton＇s principle is used to develop the non-classical nonlinear governing equation. To study the effect of the boundary conditions, two types of end conditions, i.e., fixed-fixed and fixed-free, are considered. The derived boundary value governing equation is of the fourthorder, and is solved by the homotopy analysis method （HAM）. This method is based on the Taylor series with an embedded parameter and is capable of providing very good approximations by means of only a few terms, if the initial guess and the auxiliary linear operator are properly selected. The analytical expressions are developed for the linear and nonlinear natural frequencies, which can be conveniently used to investigate the effects of the dimensionless length scale parameter, the material gradient index, and the vibration amplitude on the natural frequencies of FGMTs.

关键词： torsional vibration nonlinear vibration micro/nano-tube functionallygraded material (FGM) couple stress theory size effect

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