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国际医学放射学杂志 2019年第6期 738-739页

作者： A.Li Y.Wu B.Pulli G.R.Wojtkiewicz Y.iwamoto C.Wang 曹雄锋 Department of Radiology Huashan Hospital Fudan University

摘要目的为了确定髓过氧化物酶(MPO)分子MRI可否评估针对淋巴样和髓样炎症的联合治疗,可否在改善自身免疫性神经炎症上优于单独用药,即使是次优剂量下其优势

关键词： MRI 联合治疗神经炎症髓过氧化物酶实验性自身免疫性神经炎

SMA粒子和短纤维填充的复合材料的力学特性

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钢结构 2008年第2期23卷 78-79页

作者： Run-xin Zhang, Qing-Qing Ni, Toshiaki Natsuki and Masaharu iwamoto

形状记忆合金(SMAs)由于其可塑的记忆效果,短期弹性、高阻抗容量和其他特性,因而具有感知和激励的功能。利用SMAs独一无二的特性,结合其他材料可用来制造出智能化或灵敏的合成材料。研究利用镍钛合金短纤维和颗粒制造的环氧合成材料的... 详细信息

形状记忆合金(SMAs)由于其可塑的记忆效果,短期弹性、高阻抗容量和其他特性,因而具有感知和激励的功能。利用SMAs独一无二的特性,结合其他材料可用来制造出智能化或灵敏的合成材料。研究利用镍钛合金短纤维和颗粒制造的环氧合成材料的力学性能。由于加入了SMA,SMA/环氧合成材料具有更强的抗弯抗剪能力。特别在高温下,存储系数随着SMA显著增加。试验结果表明,SMA每增加3.5%,存储系数将有显著的增加,影响量级为环氧的6倍。当SMA相变接近120°时,存储系数增大到了最大值。SMA/ER3合成材料的损失因素随着SMA的增加而增加。基于Halpin-Tsai理论,具有SMA的薄层可以代表整个材料动力性能。相对于其他试验材料,在现有模型上得到的结论可以合理地预测这些动力响应。

关键词：形状记忆合金复合物力学特性动力响应

CT-guided radiofrequency ablation of osteoid osteoma in the long bones of the lower extremity

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World Journal of Radiology 2012年第6期4卷 278-282页

作者： Yoshiki Asayama Akihiro Nishie Kousei Ishigami Daisuke Kakihara Yasuhiro Ushijima Yukihisa Takayama Nobuhiro Fujita Tsuyoshi Tajima Kengo Yoshimitsu Shuichi Matsuda Yukihide iwamoto Hiroshi Honda Department of Clinical Radiology Graduate School of Medical SciencesKyushu University3-1-1 MaidashiHigashikuFukuoka 812-8582Japan Department of Molecular Imaging and Diagnosis Kyushu University3-1-1 MaidashiHigashi-kuFukuoka 812-8582Japan Department of Diagnostic Imaging and Nuclear Medicine Tokyo Women’s Medical University8-1 KawadachoShinjuku-kuTokyo 162-8666Japan Department of Radiology Fukuoka University7-45-1 NanakumaJonan-kuFukuoka 814-0180Japan Department of Orthopaedic Surgery Kyushu University3-1-1 MaidashiHigashi-kuFukuoka 812-8582Japan

AIM:To present our initial experience with computed tomography guided radiofrequency ablation(RFA) of osteoid osteoma(OO) in our ***:RFA was performed on eight patients(5 males and 3 females) with clinically and radiologically diagnosed OO(femoral neck,n = 4;femoral diaphysis,n = 2;tibial diaphysis,n = 1;fibular diaphysis,n = 1).Ablation was performed using an electrode with a 10-mm exposed tip for a total of 4-6 min at a targeted temperature of 90 degrees *** cooling system was *** intervention was accepted as technically successful if the tip of the electrode could be placed within the center of the *** defined clinical success as a disappearance within 2 wk after treatment of symptoms that had manifested at ***:All procedures were technically *** major or immediate complications were *** success was achieved in six of eight patients in the first procedure.A second procedure was performed for two patients who had recurrent or continued pain,and one of these cases was successfully *** overall rate of success was 87.5%(7/8).No complication was ***:Our preliminary results indicate a favorable success rate and no complications and are compatible with the previous reports of RFA of OO.

关键词： Ablation Osteoid osteoma Computed tomography

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肝细胞肝癌射频消融后的并发症

肝细胞肝癌射频消融后的并发症

Clipping Method. a Modified Procedure of Transanal Endoscopic Microsurgery （TEM）

第八届全国肿瘤介入诊疗学术大会、第一届中国抗癌协会肿瘤介入学护理专业学组会议暨国家级介入诊疗继续教育学习班、肿瘤介入治疗新进展研讨会

作者：佐藤守男 Takuya iwamoto Nobuyuki Kawai 汤超和歌山医科大学和歌山医科大学和歌山医科大学

射频消融术(RFA)自从2001在日本法定认可后,已经广泛应用于治疗肝细胞肝癌 (HCC)．针对 HCC 的治疗,RFA 用于肿瘤直径小于3cm 的多发肿瘤或者肿瘤直径小于5cm 的单发肿瘤情况下．RFA 治疗仪可分为 expansive needle 和 cool-tip 两型,... 详细信息

射频消融术(RFA)自从2001在日本法定认可后,已经广泛应用于治疗肝细胞肝癌 (HCC)．针对 HCC 的治疗,RFA 用于肿瘤直径小于3cm 的多发肿瘤或者肿瘤直径小于5cm 的单发肿瘤情况下．RFA 治疗仪可分为 expansive needle 和 cool-tip 两型,后者因为其穿刺孔直径较小而在日本更为人们接受．RFA 治疗后, 射频区域外多于5mm 的范围肿瘤可以得到局部控制．近期随访 HCC 肿瘤直径≦3cm 和＞ 3cm 在进行 RFA 后的复发率分别为6-21%和 8-40%．远期随访三年肝内治疗后远处转移率为33-85%．还有一些文献报道描述到了 RFA 的并发症问题和技术问题．本篇主要介绍 RFA 的并发症问题．

关键词：肝细胞肝癌 RFA HCC 射频消融

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Clipping Method. a Modified Procedure of Transanal Endoscopi...

甲钴胺对卒中患者未累及四肢的亚临床腕管综合征的改善作用

第六次全国大肠癌会议暨中日韩大肠癌会议

作者： Kazuto Sasaya Takenori Hada Toshio lino Michiaki Watanabe Masaichi Ogawa Yasushi Kaneko Eiichiro Miura Kenji lkeuchi Masakazu iwamoto Sadao Anazawa Yoji Yamazaki Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine Department of surgery. Daisan hospital the Jikei university school of medicine

＜正＞Transanal Endoscopic Microsurgery（TEM） has been reported to be a better operating method for resecting a rectal mucosal lesion than any other conventional transanal or transsacral procedure. One of the greatest advantage of TEM is en bloc resection with safety margin even of large sized lesion. Nevertheless. according to our clinical experiences, an enough safety margin could not be secured in more than 30％ of cases in our series, including cases in which local recurrence occurred, requiring additional surgery. To perform en bloc resection completely with a safety margin, we modified TEM by using hemoclips and proved to be useful clinical practice.

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世界核心医学期刊文摘（神经病学分册） 2005年第8期1卷 45-46页

作者： Sato Y. Honda Y. iwamoto J. 张玉龙 Departmentof Neurology Mitate Hospital 3237 Yugeta Tagawa 826-0041 Japan

Our previous study showed that overuse of the nonparetichand and wrist of the nonparetic side following stroke result in significantly more abnormal on the no nparetic side than on the hemiparetic side in terms of electrophysiologic indice s of median nerve function. The purpose of this study was to evaluate the effect s of the orally administered mecobalamin, an analogue of vitamin B12, for carpal tunnel syndrome (CTS) in the nonparetic side in patients following stroke. In a randomized open label and prospective study of stroke patients, 67 received of 1500 μg mecobalamin daily for 2 years, and the remaining 68 (untreated group) d id not. At baseline, sensory nerve conduction velocity,motor nerve conduction ve locity, sensory nerve action potentials (SNAP) at the wrist, palm-to-wrist dis tal sensory latency, palm-to-wrist SNAP, motor nerve conduction velocity compo und motor action potentials, and distal motor latency of median nerve were signi ficantly more abnormal on the nonparetic side than on the hemiparetic side or in *** the treatment 21 patients (31%) of untreated and 20 patients ( 30%) of treated group met electrophysiologic criteriafor CTS. Sensory impairmen t of the nonparetic side had lessened in the treated group. After 2 years, all e lectrophysiologic indices of nonparetic side were significantly improved in the treated group compared w ith those in the untreated group. The improvement from baseline of electrophysio logic parameters in sensory nerve in the treated group was greater than the impr ovement measured in motor nerve. There were no side effects. Oral mecobalamin tr eatment is a safe and potentially beneficial therapy for CTS in stroke patients.

关键词：腕管综合征亚临床甲钴胺感觉障碍电生理正中神经复合运动动作电位类似物随机开放

叶酸和甲钴胺治疗卒中患者髋关节骨折的随机对照试验

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世界核心医学期刊文摘（神经病学分册） 2005年第7期1卷 6-7页

作者： Sato Y. Honda Y. iwamoto J. 黄卫东 Departmentof Neurology Mitate Hospital 3237 YugetaTagawa 826-0041 Japan Dr.

Context: Stroke increases the risk of subsequent hip fracture by 2 to 4 times. Hyperhomocysteinemia is a risk factor for both ischemic stroke and osteoporotic fractures in elderly men and women. Treatment with folate and mecobalamin (vita min B12) may improve ***: To investigate whether trea tment with folate and vitamin B12 reduces the incidence of hip fractures in pati ents with hemiplegia following ***, Setting, and Patients: A double-b lind, randomized controlled study of 628 consecutive patients aged 65 years or o lder with residual hemiplegia at least 1 year following first ischemic stroke, w ho were recruited from a single Japanese hospital from April 1, 2000, to May 31, 2001. Patients were assigned to daily oral treatment with 5 mg of folate and 15 00 μg of mecobalamin,or double placebo; 559 completed the 2-year *** in Outcome Measure: Incidence of hip fractures in the 2 patient groups during th e 2-year follow-up. Results:At baseline, patients in both groups had high leve ls of plasma homocysteine and low levels of serum cobalamin and serum folate. Af ter 2 years, plasma homocysteine levels decreased by 38%in the treatment group and increased by 31%in the placebo group (P < .001). The number of hip fracture s per 1000 patient-years was 10 and 43 for the treatment and placebo groups, re spectively(P < .001). The adjusted relative risk, absolute risk reduction,and th e number needed to treat for hip fractures in the treatment vs placebo groups we re 0.20 (95%confidence interval [CI], 0.08-0.50), 7.1%(95%CI, 3.6%-10.8%) , and 14 (95%CI, 9-28), respectively. No significant adverse effects were repo rted. Conclusion: In this Japanese population with a high baseline fracture risk , combined treatment with folate and vitamin B12 is safe and effective in reduci ng the risk of a hip fracture in elderly patients following stroke.

关键词：髋关节骨折甲钴胺随机对照试验骨折发生率 Japanese 缺血性卒中骨质疏松 placebo 安慰剂 folate

Literature review of the energy sources for performing laparoscopic colorectal surgery

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World Journal of Gastrointestinal Surgery 2012年第1期4卷 1-8页

作者： Tsukasa Hotta Katsunari Takifuji Shozo Yokoyama Kenji Matsuda Takashi Higashiguchi Toshiji Tominaga Yoshimasa Oku Takashi Watanabe Toru Nasu Tadamichi Hashimoto Koichi Tamura Junji Ieda Naoyuki Yamamoto Hiromitsu iwamoto Hiroki Yamaue Second Department of Surgery Wakayama Medical UniversitySchool of Medicine

Laparoscopic surgery for colorectal disease has become widespread as a minimally invasive *** is important because the increasing availability of new devices allows us to perform procedures with a reduced length of surgery and decreased blood *** herein report the results of a literature review of energy sources for laparoscopic colorectal surgery,focused especially on 6 studies comparing ultrasonic coagulating shears(UCS) and other *** also describe our laparoscopic dissection techniques using UCS for colorectal *** short-term outcomes of surgeries using UCS and Ligasure for laparoscopiccolorectal surgery were superior to conventional *** authors have reported that the length of surgery or blood loss when Ligasure was used for laparoscopic colorectal surgery is less than when UCS was *** the other hand,a recent study demonstrated that there were no significant differences between the short-term outcomes of UCS and Ligasure for laparoscopic colorectal *** is therefore suggested that the choice of technique used should be made according to the surgeon’s *** also describe our laparoscopic dissection techniques using UCS(Harmonic ACE) for colorectal cancer with regard to the retroperitoneum dissection,dissection technique,dissection technique around the feeding artery,and various other dissection *** therefore review the outcomes of using various energy sources for laparoscopic colorectal surgery and describe our laparoscopic dissection techniques with UCS(Harmonic ACE) for colorectal cancer.

关键词： Laparoscopic surgery Ultrasonic coagulating shears Harmonic Scalpel Ligasure Colon and rectum Dissection technique

神经氨酸酶在人类免疫缺陷病毒-1分离中的应用(英文)

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神经氨酸酶在人类免疫缺陷病毒-1分离中的应用(英文)

“科技增强国力，青年开创未来——携手走向辉煌的新世纪”中国科协第三届青年学术年会

作者：辛小蜜 Tatsuo Shioda Masao Fukushima Shinichi Oka Aikichi iwamoto Yoshiyuki Nagai 东京大学医学系

我们以前报道了人类免疫缺损病毒-1型(HIV-1)的感染活性能够被神经氨酸酶(NA)介导的病毒粒子表面的去唾液酸化而激活。本文进而对神经氨酸酶用于体外HIV-1病毒分离的意义进行了探讨。在对28位HIV-1感染进行的41次病毒分离中,在HIV-1感... 详细信息

我们以前报道了人类免疫缺损病毒-1型(HIV-1)的感染活性能够被神经氨酸酶(NA)介导的病毒粒子表面的去唾液酸化而激活。本文进而对神经氨酸酶用于体外HIV-1病毒分离的意义进行了探讨。在对28位HIV-1感染进行的41次病毒分离中,在HIV-1感染者的外周血单核细胞(PBMC)或CD细胞与未感染者的PBMC或CD细胞的混合培养液中使用神经氨酸酶显著进提高了病毒分离率。与常规的方法相比,病毒分离所需要的最短时间和病毒达到最高效价的时间都明显地提前了。而且,使用神经氨酸酶后分离到的HIV-1的外膜糖蛋白gp120的V和V区域的氨基酸序列基本没有改变,这表明使用神经氨酸酶后分离到的病毒与常规方法的基本相似。因此,使用神经氨酸酶改善了体外HIV-1的病毒分离,尤其为用常规方法困难的病毒分离又提供了一个新途径。

关键词：神经氨酸酶 HIV-1 病毒分离

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纳米HS型沸石合成及长大机制的研究

无机材料学报 2000年第6期15卷 1073-1076页

作者：杜高辉卫英慧窦涛岩本知広市野濑英喜许并社太原理工大学材料科学与工程学院太原030024 日本东京大学新领域创成科学研究科物质系

通过清夜合成法成功地合成了纳米ＨＳ沸石，通过Ｘ射线粉末衍射法和高分辨率透射电镜对产物进行了表征，并对其长大机制进行了分析．结果表明，纳米颗粒包含若干个尺寸大致相同而晶体学位向不同的亚晶，其长大机制为聚集增长机制．

关键词：沸石 HRTEM 纳米HS型清液合成法长大机制