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Extracorporeal membrane oxygenation in lung transplantation:Indications,techniques and results

World Journal of Transplantation 2021年第7期11卷 290-302页

作者： Eleonora Faccioli Stefano Terzi Alessandro Pangoni ivan lomangino Sara Rossi Andrea Lloret Giorgio Cannone Carlotta Marino Chiara Catelli Andrea Dell'Amore Thoracic Surgery Unit Department of Cardiothoracic and Vascular SciencesUniversity of PadovaPadova 35128Italy

The use of extracorporeal membrane oxygenation(ECMO)in the field of lung transplantation has rapidly expanded over the past 30 *** has become an important tool in an increasing number of specialized centers as a bridge to transplantation and in the intra-operative and/or post-operative *** is an extremely versatile tool in the field of lung transplantation as it can be used and adapted in different configurations with several potential cannulation sites according to the specific need of the *** example,patients who need to be bridged to lung transplantation often have hypercapnic respiratory failure that may preferably benefit from veno-venous(VV)ECMO or peripheral veno-arterial(VA)ECMO in the case of hemodynamic ***,in an intraoperative setting,VV ECMO can be maintained or switched to a VA *** routine use of intra-operative ECMO and its eventual prolongation in the postoperative period has been widely investigated in recent years by several important lung transplantation centers in order to assess the graft function and its potential protective role on primary graft dysfunction and on ischemia-reperfusion *** review will assess the current evidence on the role of ECMO in the different phases of lung transplantation,while analyzing different studies on pre,intra-and post-operative utilization of this extracorporeal support.

关键词： Lung transplantation Extracorporeal membrane oxygenation Bridge to transplantation Support Primary graft dysfunction Ischemia-reperfusion injury

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