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Females Had a Worse T-Score at Lumbar Region and Males Had a Worse T-Score at Femoral Region among Chronic Kidney Disease

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Open Journal of Nephrology 2022年第1期12卷 60-74页

作者： Hilal al Kalbani issa al salmi Fatma al Rahbi Sumaiya al Siyabi Suad Hannawi Rheumatology Department The Royal Hospital Muscat Oman The Renal Medicine Department The Royal Hospital Muscat Oman Department of Nuclear Medicine The Royal Hospital Muscat Oman Department of Medicine Ministry of Health and Prevention Dubai UAE

Background: To evaluate bone-mineral-density-BMD determined by dual-energy X-ray absorptiometry-DEXA and bone turnover markers in chronic-kidney-disease-CKD patients. Method: An observational-clinical study of all patients who were scanned by DEXA-scan in 2018. all patients with low-bone-density or osteoporosis-based on World-Health-Organization-WHO definition were included. Results: 505 patients with abnormal-BMD, 87.3% were in early-stage CKD-stage I - II, 8.5% were in CKD-stage III - V and 4.2% did not have renal tests. 95 (18.8%) were male with a mean age of 57.0 years and 410 (81.2%) were females with a mean age of 55.8 years. Patients of ≥65 years had lower T-score than those who were younger than 65 years-old. Among CKD patients, those with late-CKD (stage III - V) had less BMD-measurements and lower T-score than those with early-CKD (stage I - II). A significant positive correlation exists between parathyroid hormone-PTH-level and the lower T-score. Female had a worse T-score at the lumbar-region whereas male had a worse T-score at the femoral-region. There was no significant difference between males and females for the T-score at hip-region. Conclusion: We observed a distribution of abnormal BMD among different age, sex and CKD groups. Measurements of BMD by DEXA might be a useful test to diagnose osteoporosis in CKD patients. Femoral and total hip areas were more affected, however DEXA might not be able to detect osteoporosis in the lumbar area of CKD patients. T-scores are lower in patients with more severe CKD and lower in elderly patients. PTH level is associated proportionally to the degree of bone loss. Early intervention and proper management must be implemented early among CKD patients with multidisciplinary team approach strategy. More studies are needed to determine if DEXA techniques are enough to distinguish the quantity of bone loss between different stages of CKD.

关键词： Bone-Mineral-Density-BMD Dual-Energy X-Ray Absorptiometry-DEXA Chronic-Kidney-Disease-CKD T-Score Lumbar Region Femoral Region Gender

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Renal allograft Thrombosis in the Early Post Transplant Period

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Open Journal of Nephrology 2013年第3期3卷 148-151页

作者： M. Budruddin issa al salmi R. Shilpa Nephrology Department Royal Hospital Muscat Oman Nephrology Department Tawam Hospital Al Ain UAE

Renal allograft thrombosis involving either the renal artery or the veins is a well known entity in clinical practice. This complication of the renal transplant surgery is more common in the early part of the post transplant period and it is usually associated with acute antibody mediated rejection. This more commonly occurs in the paediatric renal transplant and also seems to have some relation to the duration of peritoneal dialysis pretransplant. However, the occurrence of graft thrombosis in isolation without clinical or histological graft rejection is not rare. We encountered a patient in whom the renal allograft thrombosis occurred after 6 weeks of commercial renal transplantation without any histological evidence of rejection.

关键词： allograft Thrombosis Immunosuppression Cyclosporine OKT3 Hemodialysis Renogram Rejection and Pyelonephritis

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alarming Presentation of a Seemingly Common Condition in a Patient with Renal Impairment

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Open Journal of Nephrology 2013年第4期3卷 181-183页

作者： Mohammad Budruddin Muhammad Yasir Khalil issa al salmi Ramaiah Shilpa Nephrology Department Royal Hospital Muscat Oman Nephrology Department Tawam Hospital Al Ain UAE

We received a 23-year-old male, working in the Army for 18 months, with advanced renal impairment, haemoptysis and hyperkalemia. An impression of the pulmonary renal syndrome was made and he was managed aggressively with haemodialysis, plasma exchange and pulsing with methyl prednisolone. His condition improved, but the renal functions did not. The vasculitic workup including Extractable Nuclear Antigen (ENA) and Anti-Neutrophil Cytoplasmic Antibody (ANCA) which were sent on admission came out to be negative. As he apparently responded to the initial management protocol, he was subjected to renal biopsy which did not reveal any vasculitis but was consistent for end-stage renal disease. Subsequently he was subjected to lung biopsy which also was not supportive for vasculitis. However, we concluded that the initial pointers for Wegener’s granulomatosis were misleading. The haemoptysis entirely subsided as the congestion improved. He was maintained on Haemodialysis three times per week schedule and discharged to the peripheral health care facility.

关键词： Haemoptysis Renal Impairment Pulmonary Renal Syndrome Haemodialysis ENA ANCA Vasculitis Pulmonary Oedema

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Interdialytic Weight Gain in Hemodialysis Patients: Worse Hospital Admissions and Intradialytic Hypotension

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Open Journal of Nephrology 2021年第2期11卷 156-170页

作者： Yaqoob al Maimani Fady Elias issa al salmi Abdullah Aboshakra Mohamed Awad alla Suad Hannawi The Renal Medicine Department The Royal Hospital Muscat Oman Oman Medical Specialty Board Azzibah Muscat Oman The Medicine Department MOHAP Dubai UAE

Introduction: Interdialytic weight-gain (IDWG) has been linked to various complications in hemodialysis (HD) patients. Method: Prospective clinical-observational study to evaluate the effect of IDWG in HD patients on the rate of hospital admissions over a 12-month period, and the impact of high IDWG on the frequency of IDH. Results: Of the 240 patients, those who had IDWG ≥ 4%, 81% had at least one hospital admission due to volume-overload or the need for extra HD-session(s). On the other hand, only 19% of those having IDWG alyzing those who had at least one IDH episode/week;72.9% of them had IDWG ≥ 4%, while only 27.1% had IDWG Conclusion: In HD patients, the frequency of hospital admission due to volume-overload and the need for extra HD-sessions is strongly related to the amount of IDWG (>4% in our patients), the same stands for the frequency of IDH. Thus, control of IDWG in HD patients is of great importance, keeping in mind the importance of the nutrition status of HD patients that may also impact IDWG.

关键词： Interdialytic Weight-Gain Hemodialysis Hospital Admissions Intradialytic Hypotension

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Non-Diabetic Kidney Disease in Type 2 Diabetes Mellitus: A Study of 82 Patients and Review of the Literatures

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Open Journal of Nephrology 2022年第1期12卷 169-186页

作者： Ehab Mohammed issa al salmi Dawood al Riyami Saif Khan Marwa al Riyami Fatma al Rahbi Suad Hannawi The Renal Medicine Department The Royal Hospital Muscat Oman The Medicine Department Oman Medical Specialty Board Muscat Oman The Renal Medicine Department SQUH Muscat Oman The Pathology Department SQUH Muscat Oman The Medicine Department MOHAP Dubai UAE

Background: Worldwide, diabetic nephropathy-DN is the leading cause of end-stage kidney disease-ESKD, DN is a common cause of renal failure with a reported frequency of 10% - 15% in type-2-diabetes-mellitus-T2DM patients, however there is a great discrepancy between countries. The aim of the pre-sent study is to evaluate the findings of kidney biopsies performed on diabetic patients. Materials and Methods: We studied native kidney histopathological findings in the period from January 2016 till end of December 2018 done for patients with T2DM with chronic kidney diseases-CKD. Results: A total of 82 DM-patients, 50 males (61%) and 32 females (39%) with age mean (95% CI) of 50.8 (47.1 - 55.2) years for all patients, ranged between 15 to 65 years. Histological findings showed that 57.3% of patients had DN. While focal-segmental-glomerulosclerosis-FSGS was present in 20.7%—primary in 8.6% and secondary in 12.1%. IgA represented 4.9%, while Lupus nephritis, Membranous and drug induced interstitial nephritis were each present in 3.7%. MCD was present in 2.4%. Lastly diffuse proliferative GN, ANCA associated glomerulonephritis, and hypertensive nephrosclerosis accounted for 1.2%. Conclusion: The prevalence of NDKD is remarkably frequent in DM patients who underwent kidney biopsy and FSGS was the most frequent diagnosis. To get a proper histopathological diagnosis, an adequate tissue biopsy is needed with an adequate number of glomeruli. There is a great need for more consideration to biopsy diabetic patients, as the finding of NDKD requires a different therapeutic approach. This, hopefully, will help to manage these patients better and therefore, ameliorate the progression to ESKD over time and therefore delay the need for RRT.

关键词： Diabetic Nephropathy Diabetic Kidney Disease Histopathology Light Microscopy Electron Microscopy Immunofluorescence Non-Diabetic Kidney Diseases Renal Replacement Therapy (RRT)

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AMachine Learning Approach to Cyberbullying Detection in Arabic Tweets

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Computers, Materials & Continua 2024年第7期80卷 1033-1054页

作者： Dhiaa Musleh Atta Rahman Mohammed Abbas alkherallah Menhal Kamel al-Bohassan Mustafa Mohammed alawami Hayder ali alsebaa Jawad ali alnemer Ghazi Fayez al-Mutairi May issa aldossary Dalal A.aldowaihi Fahd alhaidari Department of Computer Science College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Department of Computer Information Systems College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Department of Networks and Communications College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia

With the rapid growth of internet usage,a new situation has been created that enables practicing *** has increased over the past decade,and it has the same adverse effects as face-to-face bullying,like anger,sadness,anxiety,and *** the anonymity people get on the internet,they tend to bemore aggressive and express their emotions freely without considering the effects,which can be a reason for the increase in cyberbullying and it is the main motive behind the current *** study presents a thorough background of cyberbullying and the techniques used to collect,preprocess,and analyze the ***,a comprehensive review of the literature has been conducted to figure out research gaps and effective techniques and practices in cyberbullying detection in various languages,and it was deduced that there is significant room for improvement in the Arabic *** a result,the current study focuses on the investigation of shortlisted machine learning algorithms in natural language processing(NLP)for the classification of Arabic datasets duly collected from Twitter(also known as X).In this regard,support vector machine(SVM),Naive Bayes(NB),Random Forest(RF),Logistic regression(LR),Bootstrap aggregating(Bagging),Gradient Boosting(GBoost),Light Gradient Boosting Machine(LightGBM),Adaptive Boosting(AdaBoost),and eXtreme Gradient Boosting(XGBoost)were shortlisted and investigated due to their effectiveness in the similar ***,the scheme was evaluated by well-known performance measures like accuracy,precision,Recall,and ***,XGBoost exhibited the best performance with 89.95%accuracy,which is promising compared to the state-of-the-art.

关键词： Supervised machine learning ensemble learning cyberbullying Arabic tweets NLP

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Climate change vulnerability assessment in the new urban planning process in Tanzania

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Regional Sustainability 2024年第3期5卷 1-11页

作者： issa NYASHILU Robert KIUNSI alphonce KYESSI Vice President’s Office Government CityDodoma2502Tanzania Department of Environmental Engineering and Technology Ardhi UniversityDar es Salaam35176Tanzania Institute of Human Settlements Studies Ardhi UniversityDar es Salaam35176Tanzania

Climate change vulnerability assessment is an essential tool for identifying regions that are most susceptible to the impacts of climate change and designing effective adaptation actions that can reduce vulnerability and enhance long-term resilience of these *** study explored a framework for climate change vulnerability assessment in the new urban planning process in Jangwani Ward,***,taking flood as an example,this study highlighted the steps and methods for climate change vulnerability assessment in the new urban planning *** the study area,95 households were selected and interviewed through purposeful ***,10 respondents(4 females and 6 males)were interviewed for Focus Group Discussion(FGD),and 3 respondents(1 female and 2 males)were selected for Key Informant Interviews(KII)at the Ministry of Lands,Housing and Human Settlements *** study indicated that climate change vulnerability assessment framework involves the assessment of climatic hazards,risk elements,and adaptive capacity,and the determination of vulnerability *** average hazard risk rating of flood was *** and livelihood activities and physical infrastructures both had the average risk element rating of 3.0,and ecosystems had the average risk element rating of *** capacity ratings of knowledge,technology,economy or finance,and institution were 1.6,1.9,1.4,and 2.2,*** vulnerability levels of socioeconomic and livelihood activities and physical infrastructure were very high(4.0).Ecosystems had a high vulnerability level(3.8)to *** very high vulnerability level of socioeconomic and livelihood activities was driven by high exposure and sensitivity to risk elements and low adaptive *** study recommends adoption of the new urban planning process including preparation,planning,implementation,and monitoring-evaluation-review phases that integrates climate change vulnerability assessment in

关键词： Climate change Vulnerability level Climatic hazard Risk elements Adaptive capacity New urban planning process

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Can we triumph over locally advanced cervical cancer with colossal para-aortic lymph nodes? A case report

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World Journal of Clinical Cases 2024年第10期12卷 1851-1856页

作者： Abdulla alzibdeh issa Mohamad Lina Wahbeh Ramiz Abuhijlih Fawzi Abuhijla Department of Radiation Oncology King Hussein Cancer CenterAmman 11941Jordan

BACKGROUND Para-aortic lymph nodes(PalNs)are common sites for the regional spread of cervical squamous cell carcinoma(SCC).CASE SUMMARY We report the case of a 36-year-old woman who presented with cervical SCC with multiple bulky PalNs,largest measured 4.5 cm×5 cm×10 *** patient was treated with radical intent with definitive chemoradiation using sequential doseescalated adaptive radiotherapy,followed by maintenance *** patient achieved a complete response;she has been doing well since the completion of treatment with no evidence of the disease for 2 *** Regardless of the size of PalN metastases of cervical carcinoma origin,it is still treatable(with radical intent)via concurrent *** radiotherapy allows dose escalation with minimal toxicity.

关键词： Cervical cancer Bulky Lymph node Radiotherapy Para-aortic Case report

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Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

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BIOCELL 2024年第4期48卷 559-569页

作者： YARA alZGHOUL HalA J.BANI issa AHMAD K.SANAJLEH TAQWA alABDUH FATIMAH RABABAH MAHA al-SHDAIFAT EJLal ABU-EL-RUB FATIMAH alMAHASNEH RAMADA R.KHASAWNEH AYMAN alZU’BI HUTHAIFA MAGABLEH Department of Basic Medical Sciences Faculty of MedicineYarmouk UniversityIrbidJordan

Mesenchymalstemcells(MSCs)*** the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities,which are essential to restore heart *** can be easily isolated from different sources,including bone marrow,adipose tissues,umbilical cord,and dental *** from various sources differ in their regenerative and therapeutic abilities for cardiovascular *** this review,we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function.

关键词： Bone marrow mesenchymal stem cells Adipose tissue mesenchymal stem cells Dental pulp stem cells Umbilical cord mesenchymal stem cells Cardiomyocytes Regeneration Myocardial infarction Mesenchymal stem cells Differentiation Immunomodulation

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Characteristics and trends of pediatric firepit burns: insights for prevention and safety

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World Journal of Pediatric Surgery 2024年第1期7卷 54-58页

作者： Maria Fazal Charbel Chidiac Raheel Ahmad Oussama issa Erica Hodgman alejandro V Garcia Johns Hopkins School of Medicine BaltimoreMarylandUSA Department of Surgery Division of Pediatric SurgeryJohns Hopkins School of MedicineBaltimoreMarylandUSA Division of the Biological Sciences University of ChicagoChicagoIllinoisUSA School of Medicine American University of BeirutBeirutLebanon

Introduction As fire pits grow in popularity,so do the associated burn *** study examines pediatric fire pit burns characteristics to raise awareness and promote safety *** We conducted a retrospective review of pediatric patients(al from 2016 to *** Eighty-four patients were identified,of whom 70.2%were male,with a median age of 62 *** median percent total body surface area burned was 2%(interquartile range(IQR)=1-4).Thirty-five(41.7%)patients were admitted and 7(8.3%)underwent *** and trunk burns had the highest grafting rates(66%and 33%,respectively).The hands(41.7%)and the lower extremities(27.4%)were the most frequently burned body *** leading causes of burns were ashes/hot coals(34.5%),flames(31.0%),and direct contact(25.0%),often resulting from falling into the fire(59.5%)or running or playing in activities near it(26.2%).Thirty-five(41.7%)were admitted for inpatient management,while 49(58.3%)were treated as ***(13.2%)underwent at least one reconstructive surgery,7(8.4%)had at least one rehabilitation visit,and 65(77.4%)had follow-up clinic *** median length of stay was 2 days(IQR=1.0-3.5).The peak months for burns were from August through October(n=40,46.0%),with an increase observed from 10 cases in 2016to 20 cases in *** Given the significant proportion of firepit burns resulting from unsafe fire behaviors,it is crucial that caretakers are aware of proper firepit safety *** ofevidence Il.

关键词： burns admitted prevention

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