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Factors Associated with Non-Compliance among Patients with Chronic Kidney Disease at the Departmental University Hospital of Borgou and Alibori in Parakou (Benin)

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Open Journal of Nephrology 2023年第4期13卷 420-434页

作者： Coovi Nonwanou Ignace Tokpanoude Séraphin Ahoui Damien Barikissou Georgia Elvire S. E. Djossou Sayo Djibo Gottfried Agballa Ireti Nethania Elie Ataigba ismaël landry paraiso Omer Adjibode Benoit S. Agossoukpe Rodrigue S. Kakpo-Zannou Badirou Aguemon Unité de Santé Publique de la Faculté des Sciences de la Santé (FSS) Université d’Abomey-Calavi (UAC) Cotonou Bénin Association des Médecins Communautaires du Bénin (AMCB) Parakou Bénin Service de Néphrologie Centre Hospitalier Universitaire Départemental du Borgou Alibori (CHUD/B-A) Parakou Bénin Faculté de Médecine (FMP) Institut de Formation en Soins Infirmiers et Obstétricaux (IFSIO) Parakou Bénin Service de Psychiatrie Centre Hospitalier Universitaire Départemental du Borgou Alibori (CHUD/B-A) Parakou Bénin

Introduction: Therapeutic compliance in chronic kidney disease (CKD) represents a major challenge for the prevention of this condition, which is both a non-communicable disease (NCD) and a complication of other NCDs. Non-adherence to treatment (NOT) is a factor in the poor prognosis of CKD in developing countries, particularly in Benin. The aim of this study was to evaluate therapeutic compliance (TC) and determine the factors associated with non-compliance in patients with chronic kidney disease undergoing treatment at the Departmental University Hospital of Borgou and Alibori in Parakou (CHUD/B-A). Patients and Methods: This study was carried out in the Nephrology Department of CHUD/B-A. It was a cross-sectional, descriptive study with analytical aims that ran from December 25, 2022 to March 15, 2023 and covered data from 2017 to 2022. It involved 345 patient records meeting the diagnosis of CKD according to the KDIGO 2012 criteria. NOT was defined by a Girerd score evaluation greater than or equal to 3. Data processing and analysis were performed with R software version 4.3.0. Results: The mean age (SD) of patients was 50 years (±14.9). The prevalence of NOT was 57.1%. Potential predictors of non-adherence were: monthly revenue (p = 0.009), mode of admission (p = 0.001), phytotherapy (p = 0.040), traditional treatment (p = 0.049) and quantity of drugs (p = 0.042). Conclusion: Therapeutic compliance among chronic kidney patients still needs to be improved through awareness-raising sessions.

关键词： Chronic Kidney Disease Therapeutic Non-Adherence Girerd Assessment Chronic Renal Failure Benin

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