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HIV Prevalence amongst Pregnant Women Clients Attending Antenatal Clinic at the Faith Alive Foundation and PMTCT Centre, Jos Plateau State

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World Journal of AIDS 2016年第2期6卷 59-64页

作者： Anyaka Charles Oyebode Tinuade Musa Jonah isichei mercy Anyaka Ifechi isichei Christian Department of Obstetrics and Gynaecology University of Jos/Jos University Teaching Hospital Jos Nigeria Faith Alive Foundation and Hospital Jos Nigeria Department of Surgery University of Jos/Jos University Teaching Hospital Jos Nigeria Our Lady of Apostles Hospital Jos Nigeria Department of Chemical Pathology University of Jos/Jos University Teaching Hospital Jos Nigeria

Introduction: HIV infection and AIDS is a public health problem worldwide, particularly affecting the populace in resource challenged setting like sub-saharan Africa. Women of reproductive age are mostly affected and infected with the HIV disease. Methodology: A cross-sectional study of 216 randomly selected women that booked for antenatal care at the Faith Alive Foundation and PMTCT centre Jos between 1st July to 31st December, 2014 was carried out. Information regarding age, parity, gestational age at booking, educational status and HIV sero-status of the clients was analysed. Screening test was conducted in a serial two step approval using determine and UNIGOLD as the confirmatory test, while STAT-PAK was the tie-beaker with discordant result as per the national algorithm. Positive samples were confirmed by western blot method. Result: A total of 18 women out of the 216 women studied were positive giving a sero-prevalence rate of 8.3%. The highest sero-prevalent rate was amongst 25 - 29 years age group (31.5%). Women of parity 1 - 4 constituted the highest group of 62.9%. Majority of the women 65.7% booked in the second trimester while 26.9% booked in the 3rd trimester. Most of the women 47.2% had secondary school education while only 5.6% of them had no form of education. Conclusion: HIV infection prevalence rate among antenatal attendants at Faith Alive Foundation and PMTCT centre Jos is still high. Multisectorial approach and intervention strategies should be further scaled up for the prevention of vertical transmission of the virus. However, it is worth noting that it is mainly an HIV/AIDS hospital which should have affected the outcome.

关键词： HIV Prevalence Antenatal Clinic Faith Alive Foundation and PMTCT Centre Jos Plateau State

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The general surgeon in inter-disciplinary gynaecological cancer care

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World Journal of Obstetrics and Gynecology 2013年第3期2卷 37-41页

作者： mercy Wakili isichei Bashiru Omeiza Ismaila Department of Surgery University of Jos and Jos University Teaching Hospital930001 Plateau State Nigeria

Gynaecological cancers pose a significant cancer burden globally. In 2008 cancers of the cervix, uterus and ovaries accounted for 529000(4.2%), 287000(2.3%) and 225000(1.8%) cancers, respectively, and together were responsible for 486400 deaths. Inter-disciplinary gynaecological care is an emerging concept aimed at providing more effective care by integrating different disciplines into a team working together to perform the various aspects of management at one time. This model has both advantages and potential shortcomings. In advanced healthcare systems there appears to be little role for the general surgeon. However in developing world, the general surgeon has a valuable, but complementary role in inter-disciplinary gynaecological cancer care. This role depends on the available workforce and includes, but is not limited to, the establishment of a diagnosis and treatment, including the management of complications. There is however little evidence-based research to provide guidance on the general surgeon's role in inter-disciplinary gynecologic cancer care and more research is needed.

关键词： General surgeon Inter disciplinary Diagno-sis Treatment Gynaecological Cancer

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Factors Associated with Delay in Presentation of Symptomatic Cancers among HIV Infected Persons in Plateau State, Nigeria

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World Journal of AIDS 2017年第3期7卷 157-165页

作者： mercy Wakili isichei Ayedima Michea Misauno Femi Alexander Ale isichei Christian Ogoegbunem Aisha Abubakar Kabiru Sabitu Patrick Nguku Prince Anyawu Jos University Teaching Hospital Jos Nigeria Faith Alive Foundation Jos Nigeria Ahmadu Bello University Zaria Nigeria Nigeria Field Epidemiology and Laboratory Training Program Abuja Nigeria Excellence Community Education Welfare Scheme Abuja Nigeria

There is increased incidence of cancer worldwide but much of the burden of morbidity and mortality will occur in the developing world because of cancer associated infectious diseases of which HIV infection carries a large proportion. Site-based studies show that proportion of late stage cancer presentation range between 60% - 92% in the last 10 years. There is paucity of information on reasons for the late presentation. This study is aimed to find out the factors associated with delay in presentation of symptomatic cancers among HIV infected persons in Plateau State, Nigeria. A mixed method study consists of quantitative and qualitative component. Participants were sampled from HIV infected persons diagnosed with cancer and referred to the Oncology unit. Variables on Patient and health service factors associated with late presentation of cancers were collected. Quantitative data was analyzed using Epi info version 3.5.3 and Microsoft Excel while thematic analysis was done for qualitative data. There were 503 respondents and the mean age was 48.7 ± 13.5 years. Male sex OR 2.5, (P = 0.002);Farming occupation OR 1.7, (P = 0.0005) and Primary education OR 2.0, (P = 0.0005) were associated with delay. Majority of respondents 349(69%) presented more than six months after onset of symptom. Common symptoms were pain 462(45.70%), swelling 237(23.44%) and skin discoloration 210(20.77). Their Initial reaction was mainly the use of alternative remedies 234(46.5) CI 42.1 - 51.0. Up to 274(54.47%) of participants obtained diagnosis 3 months after presenting to a health facility. Laboratory related issues 199(39.56%) and long booking time 163(32.40%) were the most common reasons for delay. Delay was found to be both patient and services related. The study also suggests that cancer symptom awareness is poor among the participants. There is no tangible cancer prevention program in the HIV/AIDs treatment program. A more in-depth knowledge of cancer is required for both the sufferer a

关键词： Delay Cancer Presentation HIV/AIDS Factors

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Unpowered Scooter-Related Injuries among Adolescents and Adults in the United States 2007-2017

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Open Journal of Emergency Medicine 2020年第1期8卷 13-20页

作者： mercy Wakili isichei Alexander Femi Ale Michael Ayedima Misauno Pamela Brown Nicholas Dean Soulakis Department of Surgery Jos University Teaching Hospital Plateau State Nigeria 727 Tulane Drive NE Albuquerque NM USA Division of Health and Biomedical Informatics Department of Preventive Medicine Northwestern University Chicago IL USA

United States Consumer Product Safety Commission (CPSC) reported a 700% increase in Emergency Department (ED) visits for injuries attributed to unpowered scooter use from January through October 2000. Our objective is to investigate injuries associated with the use of unpowered scooters among adolescents from the age of >9 years to 20 years in the National Electronic Injury Surveillance Study (NEISS) data set from 2007-2017. We analyzed unpowered scooter-related injuries in the NEISS data set using variables: SCOOTER, INJURED, AFTER, OFF, AT and IN;the product code for injuries related to unpowered scooters is 1329, and age ≥9 years and 9 - 19 - <99 years. Distribution by race: White 39.65%, Not Specified (NS) 38.94%, Black/African American 13.98% and Others (Asian, American Indians, Alaskan natives, Native Hawaiians, and Pacific Islanders) 7.43%. Body parts injured: head 16.19%, followed by face 8.49%, finger 8.30%, lower trunk 8.30%, ankle 5.60%, upper trunk 5.35%, internal injuries 0.99% and others 14.28%. Most of the injuries were mild: Treated and Discharged 89.80%, Hospitalized 7.68%, and Death in ED 0.05%. The locations of injuries were: Occurred at Home 43.47%, UNK 29.78%, Sports 12.63%, Public 6.49%, School 5.35%, and Street 2.22%. Injury trend: a rise until 2010, a decline until 2015 and, then a sharp rise through 2017. Injuries from the use of unpowered scooters are a rising threat that should be given attention. Outcome: Most of the injuries 69.80% were mild treated and discharged, 7.68% were hospitalized, while death in ED was 0.05%. Whereas: Transfer to referral hospital was about the same as in adults. Although most of these injuries were minor, head injuries could lead to more serious problems, and severe injuries could be life-threatening.

关键词： Unpowered Scooter Injuries Adolescents Adults

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Screen-and-Treat Approach in Secondary Prevention of Cervical Cancer among HIV-Infected Women in Faith Alive Hospital, Jos Nigeria

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Open Journal of Obstetrics and Gynecology 2023年第4期13卷 792-801页

作者： John Onyeji mercy W. isichei Charles U. Anyaka Emmanuel Osayi Olabanjo O. Ogunsola Oluwatomiini Ademuyiwa Abeeblahi Olafare Oluseye Ajayi Christian O. isichei Solomon A. Sagay Perpetual C. Christopher Department of Obstetrics and Gynaecology Bingham University Teaching Hospital Jos Nigeria Faith Alive Foundation Hospital Jos Nigeria Department of Surgery Jos University Teaching Hospital Jos Nigeria Department of Obstetrics and Gynaecology Jos University Teaching Hospital Jos Nigeria APIN Public Health Initiatves Abuja Nigeria Department of Chemical Pathology Jos University Teaching Hospital Jos Nigeria

Background: Cervical cancer is the fourth most common cancer among women globally, the second most common cancer in Nigeria and the most common cause of cancer-related death in Africa. In 2020, World Health Organization in its updated guidelines recommended cervical cancer screening using HPV DNA, HPV mRNA tests and subsequent treatment as appropriate. However, in resource-poor settings, Visual Inspections with Acetic Acid (VIA), Lugol’s Iodine (VILI) and subsequent treatment of precancerous lesions with thermal ablation remain the practical approaches. Objectives: To determine the prevalence of precancerous cervical lesions and associated risk factors among Women Living with HIV (WLHIV). Methods: A retrospective study on sexually active WLHIV aged 16 - 55 years screened for cervical cancer using VIA and VILI within 16 months period in Faith Alive Hospital Jos. Data were analyzed using IBM-SPSS 26. Sociodemographic characteristics of the study participants and the screening results were presented in frequency tables, and logistic regression was performed to determine risk factors of pre-cancerous lesions. Results: 1113 women were screened for cervical cancer using VIA/VILI. 994 (89.3%) were negative, 101 (9.1%) were positive for precancerous lesions, and 18 (1.6%) were suspicious of cervical cancer. The mean age of clients with pre-cancerous lesions was 41.32 ± 9.89 years. A higher positivity yield (69.4%) was found in ages between 36 and ≥55 years while a less positivity yield (30.6%) was found in age’s ≤ 35 years. History of STI had 1.64 fold risk association with precancerous lesions. Conclusion: Our study demonstrated a high prevalence of precancerous cervical lesions among WLHIV;bimodal age distribution for cancer-suspicious lesions and risk associated with STI. Thus, a “screen-and-treat” approach to cervical cancer prevention by VIA and thermal ablation in resource-poor settings should be undertaken until widespread HPV testing to triage clients is feasible.

关键词： Faith Alive Women Living with HIV VIA Screen-and-Treat

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Presentation of Undescended Testis to a Paediatric Referal Centre in Jos

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Open Journal of Pediatrics 2020年第3期10卷 438-446页

作者： Andrew Haruna Shitta Solomon Danjuma Peter Ezekiel Dido Dung Danaan Joseph Shilong Alexander Femi Ale mercy Wakili isichei Emmanuel Olorundare Ojo Michael Ayedima Misauno Lohfa Bali Chirdan Department of Surgery Jos University Teaching Hospital Jos Nigeria

Background: Undescended testis is the commonest disorder affecting the male urogenital tract. Late presentation has significant socio-medical impact on the individual’s quality of life. Aim: To evaluate the presentation of undescended testis and age at surgery in our centre. Methods: A 9-year retrospective analysis of the clinical records of patients Results: A total of 73 records were analysed, 58 (79.5%) presented > 1 year. Median age at presentation was 4 years, range 1 day - 16 years. Males 73 (100%), only 17 (23.3%) were referred by health personnel, while 56 (76.7%) self-referred. Commonest site involved was the left 33 (45.2%), 29 (39.7%) right and 11 (15.1%) bilateral. There were 13 (17.4%) who had associated congenital malformations. Hypospadias 7 (53.8%), isolated micropenis 4 (30.8%) and 1 each (7.7%) had myelomeningocele and hernia. Median age at presentation for bilateral involvement was 30 days, with associated hypospadias was 12 days, while those with isolated micropenis was 7.5 years. Median age at surgery for bilateral involvement was 2 years, overall median age at surgery was 4 years. Surgery Findings: Supra-scrotal testis 47, canalicular 25 (34.2%), and bilateral abdominal 1 (1.4%). Outcome: Wound infections 4 (5.5%), scrotal wound breakdown 1, Recurrence 3 and testicular atrophy 1. <

关键词： Undescended Testis Age at Presentation Orchidopexy

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Baseline Laboratory Profile of HIV Positive Patients on Antiretroviral Therapy in Jos North Central Nigeria: Implications for Pre-vention, Treatment, Care and Support

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World Journal of AIDS 2015年第4期5卷 328-334页

作者： Christian Ogoegbunem isichei mercy Wakili isichei Jean Emile Njab Johnson Ibidun Rotimi Tinuade Abimbola Oyebode Charles Ujunwa Anyaka Kenneth Emeka Enwerem Ayuba Ishiaku Affi Lucius Chidiebere Imoh Alexander Ogielu Abu Solomon Abiola Asorose Noel Omuya Amadu Propser Ihenacho Okonkwo Ngozi Ijeoma Okoro Department of Chemical Pathology Faculty of Medical Sciences University of Jos Jos University Teaching Hospital Jos Nigeria Faith Alive Foundation Jos Nigeria Department of Surgery Faculty of Medical Sciences University of Jos Jos University Teaching Hospital Jos Nigeria Department of Chemical Pathology Bingham University Jos Campus Jos Nigeria Department of Obstetrics and Gynaecology Faculty of Medical Sciences University of Jos Jos Nigeria AIDS Prevention Initiative in Nigeria (APIN) Abuja Nigeria

Background: We characterized baseline laboratory data of patients to identify priority treatment areas, most affected populations, anticipated clinical complications and assessed the potential burden of retention in care in Jos, Plateau State—North Central Nigeria. Methods: This study was a cross-sectional design from January 2004 to December 2005 at Faith Alive Foundation (FAF). All participants were HIV-positive and underwent pre-antiretroviral therapy counseling based on the national antiretroviral therapy (ART) guidelines and baseline laboratory testing. Data were captured on Microsoft Excel, validated on Epi Info and analyzed on SPSS version 21 at P < .05 level of significance. Results: Total of 1499 (463 men and 1036 women) participants were evaluated in this study. The age and sex related distribution of participants showed that majority (80.3% for males and 92.5% for females) were 16 - 45 years old. Amylase and creatinine were significantly higher in males than females (P = .02). Anaemia was the most common baseline abnormality (63% for females and 58% for males), while baseline CD4 count was significantly lower in males than females (P < .02) and at one-third had elevated liver enzymes (AST and ALT). Conclusion: The baseline laboratory profile of most HIV positive patients in Jos and environs of North Central–Nigeria was characterized by anaemia, elevated creatinine, and abnormal liver transaminase levels (AST and ALT). This pre-ART laboratory result suggests that HIV-positive individuals have multiple clinical abnormalities which may require more extensive care than just treating the HIV disease.

关键词： Baseline Laboratory Profile HIV-Positive Patients PEPFAR HTC Nigeria

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Screen-and-Treat Approach in Secondary Prevention of Cervical Cancer among HIV-Infected Women in Faith Alive Hospital, Jos Nigeria

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Open Journal of Obstetrics and Gynecology（妇产科期刊） 2023年第4期

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