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Effect of intensity and duration of anthropic noises on European mink locomotor activity and fecal cortisol metabolite levels

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Current Zoology 2022年第6期68卷 688-699页

作者： Lorena ORTIZ-JImENEZ Carlos IGLESIAS-mERCHAN Alba Itzel mARTıNEZ-SALAZAR isabel BARJA Department of Biology Zoology UnitUniversidad Autonoma de MadridMadrid28049Spain Department of Forest and Environmental Engineering and management Universidad Politecnica de MadridMadridSpain Geographic Information Systems Laboratory Institute of BiologyUniversidad Nacional Autonoma de MexicoMexico CityMexico Biodiversity and Global Change Research Centre(CIBC-UAm) Universidad Autonoma de MadridMadridSpain

Human activities involving noise emission can affect wild *** mink was exposed to road noise and human voice playbacks to analyze how sound intensity level and duration of both noises altered the time that individuals were active and if their fecal cortisol metabolite(FCm)levels varied.A Hierarchical Analysis Cluster was performed to establish 2 mink groups with respect to both noise source type:short duration/low intensity(SL)and long duration/high intensity(LH).We performed general linear mixed models to evaluate the variation in locomotor activity duration(s)and FCm(nanogram per gram)levels,*** results showed both road noise and human voices decreased locomotor activity duration in SL more sharply compared with LH,and human voices were the triggers that induced the most pronounced response to both exposure ***(ng/g)levels increased in SL compared with LH during road noise while the opposite happened during human *** based on sex and age of individuals were *** conclusion,noise characteristics given by the sound type determined the variations in locomotor activity duration while noise exposure level determined the variations in FCm(ng/g)*** should be paid to noisy activities(e.g.,recreational activities for visitors in protected natural areas)and loud groups of people to conserve wildlife,especially noise sensitive species.

关键词： anthropic disturbances European mink fecal cortisol metabolites noise exposure locomotor activity behavioral response

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Photosynthetic Behaviour and mineral Nutrition of Tamarix gallica Cultivated Under Aluminum and NaCl Combined Stress

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Phyton-International Journal of Experimental Botany 2019年第3期88卷 239-252页

作者： Dhouha Belhaj Sghaier Insaf Bankaji Sylvia Pedro isabel Caçador Noomene Sleimi LR.RmE-Ressources Matériaux et EcosystèmesFaculty of Sciences of BizerteUniversity of Carthage7021 JarzounaBizerteTunisie mARE-marine and Environmental Sciences Centre Faculty of Sciences of the University of LisbonPortugal

The lack of knowledge of plant tolerance and differential response to aluminum(Al)encouraged many researchers,in the last decade,to elucidate Al toxicity and tolerance *** current study reported the impact of Al,a toxic element with negative effects on plant growth and development,in halophytic plant Tamarix *** were subjected to different Al concentrations(0,200,500 and 800μm)with or without NaCl(200 mm)***,photosynthesis and mineral content were *** stress had a significant decrease on shoots’biomass production between 19 to 41%,and a little variation on chlorophyll content and photosynthetic efficiency(Fo,Fm,Fv fluorescence’s and Fv/Fm).Furthermore,the Al-treatments did not affect significantly the content of potassium,calcium,and magnesium in different plant parts,whereas NaCl addition to the medium induced a decrease in these elements’*** results have shown that *** is able to accumulate the high levels of Al in shoots and roots,6288μg.g^(-1) DW and 7834μg.g^(-1) DW *** is considered as a hyperaccumulator plant of *** addition,Na+contents in shoots and roots exceed 23000μg.g^(-1) ***,*** presents a high tolerance at the same time to Al and NaCl phytotoxicity,so it is interesting to use in phytoremediation programs.

关键词： Halophyte tolerance combined stress photosynthetic pigments chlorophyll fluorescence Al-accumulation nutrients uptake

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Production of Camphene by Isomerization Reaction on Sulfated ZrO_2

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Chinese Journal of Chemical Engineering 2000年第1期8卷 64-67页

作者： Nora Alejandra Comelli Omar masini Alfredo Lzaro Carrascull Esther Natalia Ponzi marta isabel Ponzi INTEQUI(CONICET-UNSL) Facultad de Ingenieriay Ciencias Economico Sociales25 de Mayo 384V.Mercedes (SL)ArgentinaINTEQUI(CONICET-UNSL)Facultad de Ingenieriay Ciencias Economico Sociales25 de Mayo 384V.Mercedes (SL)ArgentinaINTEQUI(CONICET-UNSL)Facultad de Ingenieriay Ciencias Economico Sociales25 de Mayo 384V.Mercedes (SL)ArgentinaINTEQUI(CONICET-UNSL)Facultad de Ingenieriay Ciencias Economico Sociales25 de Mayo 384V.Mercedes (SL)ArgentinaCINDECA(CONICET-UNLP)Calle 47 N°2571900 La PlataArgentina

The kinetics of camphene production in liquid phase from α-pinene was experimentally determined in an isothermal batch reactor. To this end, a sulfated ZrO2 catalyst was used and the reaction studied in the temperature range of 370-403 K. By analyzing the experimental data, second reaction order for α-pinene was found. A kinetic model is presented which includes term for the catalyst load used. The specific rate constant at 393K was 2.19×10^-3 mol·L^-1·min^-1, the activation energy being 93kJ·mo1·^-1. Both values are within the range of literature results.

关键词：生产工艺莰烯异构化反应硫酸盐催化剂 ZrO2 反应动力学 α-蒎烯

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m6A levels and expression of its modification genes show significant differences in breast cancer molecular subtypes

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Genes & Diseases 2023年第5期10卷 1751-1754页

作者： Tamara Kleinbielen Felix Olasagasti Elena Beristain Amparo Viguri-Díaz isabel Guerra-merino Africa García-Orad marian mde Pancorbo BIOmICs Research Group Lascaray Research CenterUniversity of the Basque Country UPV/EHUVitoria-GasteizAraba 01006Spain Bioaraba Health Research Institute Vitoria-GasteizAraba 01009Spain Department of Biochemistry and molecular Biology University of the Basque CountryUPV/EHUVitoria-GasteizAraba 01006Spain molecular Genetics Laboratory Araba University HospitalOsakidetza Basque Health ServiceVitoria-GasteizAraba 01009Spain Pathology Department Araba University HospitalVitoria-GasteizAraba 01009Spain Department of Genetics Physical Anthropology and Animal PhysiologyUniversity of the Basque Country(UPV/EHU)LeioaBizkaia 48940Spain BioCruces Bizkaia Health Research Institute BarakaldoBizkaia 48903Spain Department of Zoology and Animal Biology.University of the Basque Country(UPV/EHU) LeioaBizkaia 48940Spain

N6-methyladenosine(m6A)is the most abundant modification in eukaryotic messenger RNA.1 This modification is dynamic,reversible,and mediated by proteins characterized as methyltransferases and *** investigations have found that aberrant expression of methyltransferases and demethylases results in m6A dysregulation and,in consequence,affects the biological functions in which this modification is ***,m6A dysregulation affects the development and maintenance of various diseases,including cancer.2 For this reason,we explored the potential role that m6A modification has in invasive breast cancer of no special type(IBC-NST)and its molecular subtypes luminal A,luminal B HER2-,luminal B HER2+,HER2+,and triple-negative breast cancer(TNBC)whose degree of global m6A methylation has not yet been studied.

关键词： breast cancer HER2

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Exogenous neural stem cell transplantation for cerebral ischemia

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Neural Regeneration Research 2019年第7期14卷 1129-1137页

作者： Ling-Yi Liao Benson Wui-man Lau Dalinda isabel Sánchez-Vidana Qiang Gao Department of Rehabilitation medicine West China HospitalSichuan University Department of Rehabilitation Sciences The Hong Kong Polytechnic University

Cerebral ischemic injury is the main manifestation of stroke,and its incidence in stroke patients is 70–80%.Although ischemic stroke can be treated with tissue-type plasminogen activator,its time window of effectiveness is ***,the incidence of paralysis,hypoesthesia,aphasia,dysphagia,and cognitive impairment caused by cerebral ischemia is *** tissue regeneration can promote the recovery of the aforementioned *** stem cells can participate in the reconstruction of the damaged nervous system and promote the recovery of nervous function during self-repair of damaged brain *** stem cell transplantation for ischemic stroke has been a hot topic for more than 10 *** review discusses the treatment of ischemic stroke with neural stem cells,as well as the mechanisms of their involvement in stroke treatment.

关键词： nerve regeneration stem cell therapy neural stem cells cell transplantation ischemic stroke cerebral ischemia neuroplasticity functional recovery neural regeneration

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Role of the tissue microenvironment as a therapeutic target in hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第15期20卷 4128-4140页

作者： Bhavna Rani Yuan Cao Andrea malfettone Ciprian Tomuleasa isabel Fabregat Gianluigi Giannelli Department of medical Biosciences and Human Oncology Padiglione Semeiotica Medica70124 BariItaly Bellvitge Biomedical Research Institute (IDIBELL) 08028 BarcelonaSpain Department of Hematology Center for Genomics and Translational MedicineIuliu Hatieganu University of Medicine and Pharmacy400012 Cluj NapocaRomania Department of Physiological Sciences Ⅱ University of Barcelona08028 BarcelonaSpain

Hepatocellular carcinoma is difficult to treat,primarilybecause the underlying molecular mechanisms drivingclinical outcome are still poorly *** suggests that the tissue microenvironmenthas a role in the biological behavior of the *** clinical issue is to identify the best target fortherapeutic ***,we discuss the hypothesis that the entire tissue microenvironment might beconsidered as a biological ***,the tissuemicroenvironment consists of several cellular and biochemical components,each of which displays a distinctbiological *** discuss the major components ofthis environment and consider how they may interactto promote tumor/host crosstalk.

关键词： Tissue microenvironment Hepatocellular carcinoma Transforming growth factor-beta Laminin-5 Cancer stem cells Therapy Target therapy

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Fences and hydropower:Important but overlooked Human Footprint

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Geography and Sustainability 2023年第4期4卷 340-342页

作者： Jian Sun isabel C.Barrio State Key Laboratory of Tibetan Plateau Earth System Resources and EnvironmentInstitute of Tibetan Plateau ResearchChinese Academy of SciencesNo.16 Lincui RoadChaoyang DistrictBeijing 100101China Faculty of Environmental and Forest Sciences Agricultural University of IcelandReykjavík 112Iceland

Human activities have impacted 77%of the terrestrial ecosystems(excluding Antarctica),and the remaining areas are becoming increasingly *** spatiotemporal dynamics of Human Footprint has been used to evaluate the cumulative interference on terrestrial environments ***,fences and hydropower,two widespread and rapidly expanding infrastructures,have not been considered regarding Human Footprint,despite their complicated and extensive effects on ecosystem functioning and species *** work has proved that fences increase habitat fragmentation,disrupt migratory routes,inadvertently trap and kill wildlife,and hinder genetic *** construction also caused habitat loss,fragmentation,and *** impacts have received global concern,but fences around the world are difficult to be detected due to the limitations of current cartographic ***,the effect of hydropower on the terrestrial environment has been underestimated,making the research on this topic at a global scale still in its ***,building an observation network of global fences and hydropower is a necessary step to move forward in the assessment of the impact of human activities on our planet,but also to better provide scientific support for policy-making regarding global biodiversity conservation,the identification of protected areas,and the prioritization of ecological restoration areas.

关键词： Global observation network Spatiotemporal dynamics Fences Hydropower Human Footprint

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What do we know about pseudodementia?

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General Psychiatry 2023年第4期36卷 231-238页

作者： Salomémouta isabel Fonseca Vaz miguel Pires Sara Ramos Diana Figueiredo Departamento de Psiquiatria e Saúde mental Unidade Local de Saude da Guarda EPEGuardaPortugal Departamento de Saúde mental Unidade Local de Saúde de Matosinhos EPEMatosinhosPortugal

Depression and dementia can lead to generalised cognitive and memory ***,differentiating these disorders is important and *** is a term used clinically to describe symptoms that resemble dementia but are caused by other conditions(most frequently depression),rather than being recognised as an official *** is characterised by a cognitive impairment that mimics dementia but which does not have its origin in neurological degeneration,deriving instead from functional psychiatric *** condition is more commonly observed in older adults(particularly those over the age of 50 or 60 years),and its risk factors overlap with those for *** is essentially characterised by deficits in memory,executive function and speech and,therefore,can easily be confused with dementia,although there are aspects that allow its *** pseudodementia can be difficult,especially as there is significant overlap between its symptoms and those of other ***,it is important to recognise characteristic aspects of this disorder,as its correct identification is essential for proper treatment.

关键词： degeneration overlap instead

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Hydroxychloride trace minerals have a positive effect on growth performance,carcass quality and impact ileal and cecal microbiota in broiler chickens

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Journal of Animal Science and Biotechnology 2021年第3期12卷 1112-1124页

作者： Sandra J.A.van Kuijk Yanming Han Ana isabel Garcia-Ruiz Ana Rodiles Trouw Nutrition R&D P.O.Box 2993800AGAmersfoortthe Netherlands Trouw Nutrition R&D 45950 Casarrubios del MonteToledoSpain.

Background:The objective was to study the effect of hydroxychloride trace minerals(HTm)on growth performance,carcass quality and gut microbiota of broiler chickens in comparison to sulphate trace minerals(STm).In total 1440 male Ross 308 day-old chicks were divided into 12 replicate pens with 30 birds each per *** different treatments were tested according to a 2×2 factorial study design,where the animals received a three phase diet containing either inorganic Zn from sulphates or Zn from HTm in high(80 mg/kg Zn)or low Zn dosage(20 mg/kg Zn).In all treatments 15 mg/kg Cu was added from the same mineral source as the *** weight and feed intake were measured on day 0,10,27 and 34,while carcass and breast meat yields were measured at the end of the study(day 34).In addition,high-throughput sequencing analysis was performed in digesta samples from ileum and cecum to study the gut microbiome(day 34).Results:The results showed an improved(Pbroiler chickens fed HTm,regardless of Zn level,on day 27,while on day 34 this effect remained as a tendency(P=0.0542).In the overall study period,birds fed HTm had a higher(Pmpared to birds fed *** mineral source did not affect the carcass characteristics,however,feeding 80 mg/kg Zn resulted in a significantly higher(P=0.0171)breast meat yield,regardless of ***-throughput sequencing analysis of the microbiota revealed a higher microbial diversity in the ileum and cecum of HTm fed birds compared to STm fed *** differences were mainly found in the cecum,specifically between the group fed high and low Zn levels from *** correlated with the mineral contents observed in the cecal *** both groups fed 80 mg/kg Zn,the HTm group had more Streptococcaceae,Streptococcus,Clostridia,Weissella and Leuconostocaceae compared to the STm ***:HTm improved growth performance of broiler chickens;and th

关键词： broiler chickens Growth performance Gut microbiota Hydroxychloride trace minerals

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Using meshes to change the characteristics of simulated rainfall produced by spray nozzles

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International Soil and Water Conservation Research 2014年第2期2卷 67-78页

作者： Sílvia C.P.Carvalho João L.m.P.de Lima m.isabel P.de Lima Department of Civil Engineering Faculty of Science and TechnologyUniversity of CoimbraCoimbraPortugal Department of Civil Engineering Campus II-University of CoimbraRua Luís Reis Santos3030-788 CoimbraPortugal

Rainfall simulators have been used for many years contributing to the understanding of soil and water conservation ***,rainfall simulators’design and operation might be rather demanding for achieving specific rainfall intensity distributions and drop characteristics and are still open for *** study explores the potential of combining spray nozzle simulators with meshes to change rainfall characteristics,namely drop properties(drop diameters and fall speeds).A rainfall simulator laboratory set-up was prepared that enabled the incorporation of different wire meshes beneath the spray *** tests conducted in this exploratory work included different types of spray nozzles,mesh materials(plastic and steel),square apertures and wire thicknesses,and positions of the meshes in relation to the *** intensity and drop size distribution and fall speed were *** showed that the meshes combined with nozzles increased the mean rainfall intensity on the 1 m^(2) control plot below the nozzle and altered the rain drops’properties,by increasing the mass-weighted mean drop diameter,for example.

关键词： Rainfall simulators Spray nozzle meshes Drop characteristics

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